Dr Kehinde Ross
Lecturer in Biochemistry/Cell Biology - School of Pharmacy and Biomolecular Sciences
Tel: 0151 231 2567
Email: o.k.ross@ljmu.ac.uk
Dr Kehinde Ross is now a lecturer within the School of Biomolecular Sciences, specialising in Biochemistry/Cell Biology. Kehinde's background is in cytokine and calcium signalling mechanisms, and he has a strong interest in multidisciplinary research. He is also investigating the role and regulation of microRNAs in physiological processes and in disease and has an ongoing interest in investigative Dermatology. Previous awards won by him include:
- National Endowment for Science, Technology and Arts (NESTA) Crucible Award 2007. http://www.nesta.org.uk/crucible/
- MRC Discipline Hopping Award 2006.
- British Society for Investigative Dermatology Travel Award 2005.
- Newcastle University/Wellcome Trust ‘Value in People’ Award 2004
He is a member of the Biochemical Society and the Physiological Society and is a reviewer for the British Journal of Dermatology.
Research in his laboratory is funded by the British Skin Foundation.
Research Grants
British Skin Foundation, December 2008: Does interleukin-22-dependent upregulation of microRNA contribute to the psoriatic phenotype? £69,700. (PI).
The North East Skin Research Fund, February 2008: Regulation of keratinocyte microRNA by S100 proteins. £3,820. (PI).
MRC Discipline Hopping Award, April 2006: Computational reconstruction of a TGFb-Smad network. £84,487. (PI).
The Physiological Society Vacation Studentship, June 2006: Analysis of iPLA2 mobility in keratinocytes. £1200. (PI).
Stiefel Laboratories, October 2005: Intracellular calcium signalling in normal and psoriatic keratinocytes and regulation by anti-psoriatic drugs. £239,360. (Co-I).
Newcastle Healthcare Charity Award, March 2005. Regulation of Calcium-sensing Receptor Expression in Keratinocytes and Psoriasis. £39,692. (Co-I).
Schools outreach and public engagement with science
- Mentor on the Aimhigher Greater Merseyside's REACHing High, which aims to motivate Black boys to pursue university and higher education.
- Nuffield Bursary Scheme: microRNA function in mammalian cells (two year 12 students on a 4-week laboratory placement) - July 2009
- DNA technology in the 21st century: one day master class on plasmids, plasmid extraction, agarose gel electrophoresis for DNA visualization, and personalized medicine - July 2009
Students from King David, St Edwards, Bellerive, Fazakerley High and Christ the King.
To view a pdf copy of the presentation please click here
- Aimhigher Greater Merseyside, http://www.ahgtm.ac.uk/. Three-day workshop for year 10 (key stage 4) students. April 2009
Cell Biology: mammalian cell culture and trypsinization
Fluorescence Microscopy: visualization of mammalian cell nuclei
DNA purification: plasmid DNA extraction from Lactobacillus casei (Yakult)
Students from Archbishop Blanch, Fazakerley High, Pensby Girls, Chesterfield High,The Bankfield.
- Researchers in Residence placement, Thomas Rotherham College, Rotherham. December 2007 and June 2008 (three workshops).
Talks: Stems Cells – The Promise and the Problems; The Rise of the Cybrids; MC1R – The Red Connection.
Activities: Introduction to Cell Culture. SNP analysis.
- Centre for Life/North East England Stem Cell Institute (NESCI): Introducing Stem Cells Weekend.March 2008, Millennium Square, Durham.
- Contributor to the Sense About Science publication There Goes the Science Bit.... (2007) which can be downloaded from http://www.senseaboutscience.org.uk/voys/theregoesthesciencebit.pdf
K. Ross, G. Parker, M. Whitaker and N.J. Reynolds (2008). Inhibition of calcium-independent phospholipase A impairs agonist-induced calcium entry in keratinocytes.British Journal of Dermatology 158:31-7.
Kehinde Ross, Michael Whitaker and Nick J Reynolds (2007). Agonist-induced Calcium Entry correlates with STIM1 translocation. Journal of Cellular Physiology 211:569-576. Rapid Communication.
P. Hampton, K.Ross, N.J. Reynolds (2007). Increased nuclear beta-catenin in suprabasal involved psoriatic epidermis.British Journal of Dermatology 157:1168-1177.
M.J. Hoogduijn, E. Cemeli, K. Ross, D. Anderson, A.J. Thody and J.M. Wood (2004). Melanin Protects Melanocytes and Keratinocytes Against H2O2-induced DNA Strand Breaks Through its Ability to Bind Ca2+. Experimental Cell Research 294:60-67.Lin Yang, Kehinde Ross, and Eva E. Qwarnstrom (2003). RelA Control Of IkBa Phosphorylation: A Positive Feedback Loop For High Affinity NF-kB Complexes. Journal of Biological Chemistry 278: 30881 - 30888.
Kehinde Ross, Lin Yang, Steve Dower, Filippo Volpe and François Guesdon (2002). Identification of Threonine 66 as a Functionally Critical Residue of the Interleukin-1 Receptor-associated Kinase (IRAK). Journal of Biological Chemistry 277: 37414-37421.
Published Abstracts
S. Milner, K. Ross, T. Thody and N.J. Reynolds (2008). The anti-psoriatic drug dithranol inhibits agonist-induced calcium flux and the translocation of stromal-interacting molecule 1. British Journal of Dermatology 158:899.
R. Jans, S. Sikkink, R. Flockhart, W. al-Daraji, A.M. Brown, K. Ross and N.J. Reynolds (2008). NFAT2 – a novel regulator of both keratinocyte proliferation and differentiation. British Journal of Dermatology 158:905.
P. Fearon, A.A. Lonsdale-Eccles, K. Ross, C. Todd, A. Allain, N.J. Reynolds (2007). Secretion of chemotactic cyclophilin B by keratinocytes is regulated through its cyclosporin binding site. Journal of Investigative Dermatology (2007) 127:S39.
A.A. Lonsdale-Eccles, P. Fearon, K. Ross, F. Allain and N.J. Reynolds (2007). Location, mobility and secretion of cyclophilin B in keratinocytes is regulated through its ciclosporin A binding site. British Journal of Dermatology 156: 1097.
P.J. Hampton, K. Ross and N.J. Reynolds (2007). Lithium inhibits the transcriptional activation, mRNA and protein expression of transglutaminase 1 in keratinocytes. British Journal of Dermatology 156:1106.
K. Ross and N.J. Reynolds (2006). Regulation of calcium entry in Keratinocytes by calcium-independent PLA2 and STIM1. Journal of Investigative Dermatology 126: S94
K. Ross and N. J. Reynolds (2005). Inhibition of calcium-independent phospholipase A impairs lysophosphatidic acid-induced calcium entry in keratinocytes. British Journal of Dermatology 152: 836.
K. Ross and N. J. Reynolds (2004). Agonist Induced Ca2+ oscillations and Ca2+ entry in Keratinocytes. Journal of Investigative Dermatology 123:A60.
K.Ross, M.J.Whitaker and N.J. Reynolds (2004). Differential intracellular calcium responses to proliferative signals in keratinocytes. British Journal of Dermatology 150: 185.
