Journal article

Barrett JS, Strauss JA, Chow LS, Shepherd SO, Wagenmakers AJM, Wang Y. 2024. GLUT4 localisation with the plasma membrane is unaffected by an increase in plasma free fatty acid availability Lipids in Health and Disease, 23 :1-13 DOI Author Url Publisher Url Public Url

Srisawat K, Stead CA, Hesketh K, Pogson MA, Strauss JA, Cocks MS, Siekmann I, Phillips SM, Lisboa PJ, Shepherd SO, Burniston JG. 2023. People with obesity exhibit losses in muscle proteostasis that are partly improved by exercise training Proteomics, :1-14 DOI Author Url Publisher Url Public Url

McHaffie SJ, Langan-Evans C, Strauss JA, Areta JL, Rosimus C, Evans M, Waghorn R, Morton JP. 2023. Under-Fuelling for the Work Required? Assessment of Dietary Practices and Physical Loading of Adolescent Female Soccer Players during an Intensive International Training and Game Schedule Nutrients, 15 :1-15 DOI Author Url Publisher Url Public Url

McLaughlin M, Hesketh KL, Horgan SL, Florida-James G, Cocks M, Strauss JA, Ross M. 2023. Ex Vivo treatment of coronary artery endothelial cells with serum post-exercise training offers limited protection against in vitro exposure to FEC-T chemotherapy Frontiers in Physiology, 14 DOI Author Url Publisher Url Public Url

McHaffie SJ, Langan-Evans C, Morehen JC, Strauss JA, Areta JL, Rosimus C, Evans M, Elliott-Sale KJ, Cronin CJ, Morton JP. 2022. Normalising the conversation: a qualitative analysis of player and stakeholder perceptions of menstrual health support within elite female soccer Science and Medicine in Football, 6 :633-642 DOI Author Url Publisher Url Public Url

Oosthuyse T, Strauss JA, Hackney AC. 2022. Understanding the female athlete: molecular mechanisms underpinning menstrual phase differences in exercise metabolism European Journal of Applied Physiology, DOI Author Url Publisher Url Public Url

McHaffie SJ, Langan-Evans C, Morehen JC, Strauss JA, Areta JL, Rosimus C, Evans M, Elliott-Sale KJ, Cronin CJ, Morton JP. 2022. Carbohydrate fear, skinfold targets and body image issues: A qualitative analysis of player and stakeholder perceptions of the nutrition culture within elite female soccer. Science and Medicine in Football, DOI Author Url Publisher Url Public Url

Baumert P, Cocks MS, Strauss JA, Shepherd SO, Drust B, Lake MJ, Stewart CE, Erskine RM. 2022. Polygenic Mechanisms Underpinning the Response to Exercise-Induced Muscle Damage in Humans: in vivo and in vitro Evidence Journal of Cellular Physiology, DOI Author Url Publisher Url Public Url

Barrett J, Whytock KL, Strauss JA, Wagenmakers AJM, Shepherd SO. 2022. High intramuscular triglyceride turnover rates and the link to insulin sensitivity: Influence of obesity, type 2 diabetes and physical activity. Applied Physiology, Nutrition, and Metabolism, DOI Author Url Publisher Url Public Url

Hesketh KL, Jones H, Kinnafick F, Shepherd SO, Wagenmakers AJM, Strauss JA, Cocks MS. 2021. Home-Based HIIT and Traditional MICT Prescriptions Improve Cardiorespiratory Fitness to a Similar Extent Within an Exercise Referral Scheme for At-Risk Individuals Frontiers in Physiology, 12 DOI Author Url Publisher Url Public Url

Hesketh KL, Church H, Kinnafick F, Shepherd SO, Wagenmakers AJM, Cocks MS, Strauss JA. 2021. Evidence-based vs. social media based high-intensity interval training protocols: Physiological and perceptual responses. PLoS One, 16 DOI Author Url Publisher Url Public Url

Fell JM, Hearris MA, Ellis DG, Moran JEP, Jevons EFP, Owens DJ, Strauss JA, Cocks MS, Louis JB, Shepherd SO, Morton JP. 2021. Carbohydrate improves exercise capacity but does not affect subcellular lipid droplet morphology, AMPK and p53 signalling in human skeletal muscle The Journal of Physiology, DOI Author Url Publisher Url Public Url

Baumert P, Temple S, Stanley JM, Cocks MS, Strauss JA, Shepherd SO, Drust B, Lake MJ, Stewart CE, Erskine RM. 2021. Neuromuscular fatigue and recovery after strenuous exercise depends on skeletal muscle size and stem cell characteristics. Scientific Reports, 11 DOI Author Url Publisher Url Public Url

Maasar M-F, Turner DC, Gorski PP, Seaborne RA, Strauss JA, Shepherd SO, Cocks MS, Pillon NJ, Zierath JR, Hulton AT, Drust B, Sharples AP. 2021. The Comparative Methylome and Transcriptome After Change of Direction Compared to Straight Line Running Exercise in Human Skeletal Muscle. Frontiers in Physiology, 12 DOI Author Url Publisher Url Public Url

Hearris MA, Owens DJ, Strauss JA, Shepherd SO, Sharples AP, Morton JP, Louis JB. 2020. Graded reductions in pre-exercise glycogen concentration do not augment exercise-induced nuclear AMPK and PGC-1α protein content in human muscle. Experimental Physiology, 105 :1882-1894 DOI Author Url Publisher Url Public Url

Whytock KL, Shepherd SO, Cocks MS, Wagenmakers AJM, Strauss JA. 2020. Young, healthy males and females present cardiometabolic protection against the detrimental effects of a 7-day high-fat high-calorie diet European Journal of Nutrition, DOI Author Url Publisher Url Public Url

Nolan A, Brett R, Strauss JA, Stewart CE, Shepherd SO. 2020. Short-term, but not acute, intake of New Zealand blackcurrant extract improves insulin sensitivity and free-living postprandial glucose excursions in individuals with overweight or obesity European Journal of Nutrition, DOI Author Url Publisher Url Public Url

Strauss JA, Shepherd DA, Macey M, Jevons EFP, Shepherd SO. 2020. Divergence exists in the subcellular distribution of intramuscular triglyceride in human skeletal muscle dependent on the choice of lipid dye. Histochemistry and Cell Biology, DOI Author Url Publisher Url Public Url

Strauss JA, Ranasinghe C, Cowley E, Schwingshackl L, Shepherd SO, Chaplin M, Garner P. 2020. High-intensity interval training for reducing cardiometabolic syndrome in healthy but sedentary populations Cochrane Database of Systematic Reviews, 2020 DOI Publisher Url

Impey SG, Jevons EFP, Mees G, Cocks MS, Strauss JA, Chester N, Laurie I, Target D, Hodgson A, Shepherd SO, Morton JP. 2020. Glycogen Utilization during Running: Intensity, Sex, and Muscle-specific Responses. Medicine and Science in Sports and Exercise, DOI Author Url Publisher Url Public Url

Jevons EFP, Gejl KD, Strauss JA, Ørtenblad N, Shepherd SO. 2020. Skeletal muscle lipid droplets are resynthesized before being coated with perilipin proteins following prolonged exercise in elite male triathletes. American Journal of Physiology Endocrinology and Metabolism, 318 :E357-E370 DOI Author Url Publisher Url Public Url

Whytock KL, Parry SA, Turner MC, Woods RM, James LJ, Ferguson RA, Ståhlman M, Borén J, Strauss JA, Cocks MS, Wagenmakers AJM, Hulston CJ, Shepherd SO. 2020. A 7-day high-fat, high-calorie diet induces fibre-specific increases in intramuscular triglyceride and perilipin protein expression in human skeletal muscle Journal of Physiology, 598 :1151-1167 DOI Author Url Publisher Url Public Url

Roerink SHPP, Cocks MS, Wagenmakers MAEM, Rodighiero RP, Strauss JA, Shepherd SO, Plantinga TS, Thijssen DHJ, Hopman MTE, Pereira AM, Smit JW, Wagenmakers AJM, Netea-Maier RT, Hermus ARMM. 2019. Decreased Aerobic Exercise Capacity After Long-Term Remission From Cushing Syndrome: Exploration of Mechanisms. Journal of Clinical Endocrinology and Metabolism, 105 DOI Author Url Publisher Url Public Url

Srisawat K, Hesketh KL, Cocks MS, Strauss JA, Edwards BJ, Lisboa PJ, Shepherd SO, Burniston JG. 2019. Reliability of Protein Abundance and Synthesis Measurements in Human Skeletal Muscle. Proteomics, 20 DOI Author Url Publisher Url Public Url

Scott SN, Shepherd SO, Strauss JA, Wagenmakers AJM, Cocks MS. 2019. Home-based high-intensity interval training reduces barriers to exercise in people with type 1 diabetes Experimental Physiology, DOI Author Url Publisher Url Public Url

Parry SA, Turner MC, Woods RM, James LJ, Ferguson RA, Cocks M, Whytock KL, Strauss JA, Shepherd SO, Wagenmakers AJM, van Hall G, Hulston CJ. 2019. High-fat overfeeding impairs peripheral glucose metabolism and muscle microvascular eNOS Ser1177 phosphorylation. Journal of Clinical Endocrinology and Metabolism, 105 DOI Author Url Publisher Url Public Url

Hammond KM, Sale C, Fraser W, Tang J, Shepherd SO, Strauss JA, Close GL, Cocks MS, Louis J, Pugh JN, Stewart CE, Sharples AP, Morton JP. 2019. Post-exercise carbohydrate and energy availability induce independent effects on skeletal muscle cell signalling and bone turnover: implications for training adaptation The Journal of Physiology, 597 :4779-4796 DOI Author Url Publisher Url Public Url

Scott SN, Shepherd SO, Hopkins ND, Dawson EA, Strauss JA, Wright DJ, Cooper RG, Kumar P, Wagenmakers AJM, Cocks MS. 2019. Home-HIT improves muscle capillarisation and eNOS/NAD(P)Hoxidase protein ratio in obese individuals with elevated cardiovascular disease risk. Journal of Physiology, DOI Author Url Publisher Url Public Url

Hesketh K, Shepherd SO, Strauss JA, Low DA, Cooper RG, Wagenmakers AJM, Cocks MS. 2019. Passive Heat Therapy in Sedentary Humans Increases Skeletal Muscle Capillarisation and eNOS Content but Not Mitochondrial Density or GLUT4 Content. AJP - Heart and Circulatory Physiology, 317 :H114-H123 DOI Author Url Publisher Url Public Url

Seaborne RA, Strauss JA, Cocks MS, Shepherd SO, O'Brien TD, van Someren KA, Bell PG, Murgatroyd C, Morton JP, Stewart CE, Mein CA, Sharples AP. 2018. Methylome of human skeletal muscle after acute & chronic resistance exercise training, detraining & retraining Scientific Data, 5 DOI Author Url Publisher Url Public Url

Strauss JA, Willems MET, Shepherd SO. 2018. New Zealand blackcurrant extract enhances fat oxidation during prolonged cycling in endurance-trained females. European Journal of Applied Physiology, DOI Author Url Publisher Url Public Url

Whytock KL, Shepherd SO, Wagenmakers AJM, Strauss JA. 2018. Hormone sensitive lipase preferentially redistributes to perilipin-5 lipid droplets in human skeletal muscle during moderate-intensity exercise. Journal of Physiology, DOI Author Url Publisher Url Public Url

Seaborne RA, Strauss JA, Cocks MS, Shepherd SO, O'Brien TD, van Someren KA, Bell PG, Murgatroyd C, Morton JP, Stewart CE, Sharples AP. 2018. Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy Scientific Reports, 8 DOI Author Url Publisher Url Public Url

Whytock KL, Jevons EFP, Strauss JA, Shepherd SO. 2017. Under the microscope: insights into limb-specific lipid droplet metabolism. J Physiol, DOI Author Url Publisher Url

Shepherd SO, Strauss JA, Wang Q, Dube JJ, Goodpaster B, Mashek DG, Chow LS. 2017. Training alters the distribution of perilipin proteins in muscle following acute free fatty acid exposure. Journal of Physiology, DOI Author Url Publisher Url Public Url

Strauss JA, Shaw CS, Bradley H, Wilson OJ, Dorval T, Pilling J, Wagenmakers AJM. 2016. Immunofluorescence microscopy of SNAP23 in human skeletal muscle reveals colocalization with plasma membrane, lipid droplets, and mitochondria. Physiological Reports, 4 DOI Author Url Publisher Url Public Url

Bradley H, Shaw CS, Bendtsen C, Worthington PL, Wilson OJ, Strauss JA, Wallis GA, Turner AM, Wagenmakers AJM. 2015. Visualization and quantitation of GLUT4 translocation in human skeletal muscle following glucose ingestion and exercise. Physiological Reports, 3 :1-11 DOI Author Url Publisher Url Public Url

Wagenmakers AJM, Strauss JA, Shepherd SO, Keske MA, Cocks M. 2015. Increased muscle blood supply and transendothelial nutrient and insulin transport induced by food intake and exercise: effect of obesity and ageing. Journal of Physiology, :1-16 DOI Author Url Publisher Url Public Url

Shaw CS, Clark JA, Shepherd SO. 2013. HSL and ATGL: The movers and shakers of muscle lipolysis Journal of Physiology, 591 :6137-6138 DOI Author Url Publisher Url

Shaw CS, Clark J, Wagenmakers AJM. 2010. The effect of exercise and nutrition on intramuscular fat metabolism and insulin sensitivity Annual Review of Nutrition, 30 :13-34 DOI Author Url Publisher Url

Jeukendrup AE, Currell K, Clarke J, Cole J, Blannin AK. 2009. Effect of beverage glucose and sodium content on fluid delivery. Nutr Metab (Lond), 6 :9 DOI Author Url Publisher Url

preprint

Srisawat K, Stead C, Hesketh K, Pogson M, Strauss J, Cocks M, Siekmann I, Phillips S, Lisboa P, Shepherd S, Burniston J. 2023. Muscle of obese insulin-resistant humans exhibits losses in proteostasis and attenuated proteome dynamics that are improved by exercise training bioRxiv DOI Publisher Url

Maasar MF, Turner D, Gorski P, Seaborne R, Strauss J, Shepherd S, Cocks M, Pillon N, Zierath J, Hulton A, Drust B, Sharples A. 2020. The methylome and comparative transcriptome after high intensity sprint exercise in human skeletal muscle bioRxiv DOI Publisher Url

Baumert P, Temple S, Stanley JM, Cocks M, Strauss JA, Shepherd SO, Drust B, Lake MJ, Stewart CE, Erskine RM. 2019. Neuromuscular fatigue and recovery after strenuous exercise depends on skeletal muscle size and stem cell characteristics DOI Publisher Url

Conference publication

Strauss JA, Shepherd DA, Jevons EFP, Macey M, Shepherd SO. 2019. Bodipy Is Superior To Oil-red-O For Detecting And Quantifying Intramuscular Triglyceride In Human Skeletal Muscle MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, Annual Meeting of the American-College-of-Sports-Medicine (ACSM) 51 :719-719 DOI Author Url Publisher Url

Shepherd S, Jevons EFP, Strauss JA, Gejl KD, Jensen K, Hvid LG, Frandsen U, Sahlin K, Ortenblad N. 2019. Acute Carbohydrate Restriction During Recovery From Prolonged Exercise Enhances Intramuscular Triglyceride Resynthesis MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, Annual Meeting of the American-College-of-Sports-Medicine (ACSM) 51 :382-382 DOI Author Url Publisher Url

Wagenmakers AJM, Hesketh K, Shepherd SO, Strauss JA, Low DA, Cooper RJ, Cocks M. 2019. Passive Heat Therapy in Sedentary Humans Improves Aerobic Capacity and Insulin Sensitivity via Increases in Skeletal Muscle Capillarisation and eNOS FASEB JOURNAL, Experimental Biology Meeting (EB) 33 Author Url

Macey M, Strauss JA, Shepherd SO. 2019. Fibre and region-specific differences in the subcellular distribution and morphology of lipid droplets in the skeletal muscle of trained, sedentary, obese males with Type 2 diabetes DIABETIC MEDICINE, 36 :49-49 Author Url

Strauss JA, Shaw CS, Davis ET, Pilling J, Wagenmakers AJM. 2015. The association of SNAP23 with the mitochondrial network is reduced in skeletal muscle of obese sedentary females 20th Annual Congress of European College of Sport Science

Shepherd S, Wilson O, Bradley H, Clark J, Cocks M, Thogersen-Ntoumani C, Taylor A, Anton W, Shaw C. 2013. Group-based High Intensity Interval Training Improves Adherence and Reduces Cardio-metabolic Risk Factors in Sedentary Individuals MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 60th Annual Meeting of the American-College-of-Sports-Medicine 45 :509-509 Author Url

Clark JA, Shaw CS, Davis E, Pilling J, Wagenmakers AJM. 2013. The association of SNAP23 with the mitochondrial network is reduced in skeletal muscle of obese sedentary females Obesity Facts: the European journal of obesity, European Congress on Obesity 6 :35

Clark JA, Shaw CS, Bradley H, Wilson OJ, Wagenmakers AJM. Visualising the subcellular distribution of SNAP23 in human skeletal muscle 15th International Biochemistry of Exercise Congress

Research Grants Awarded:

Society for Endocrinology Early Career Researcher Grant, Discovery of new members of the lipid droplet-protein interactome in human skeletal muscle and their role in the development of insulin resistance, Grant value (£): 9,993, Duration of research project: 1 year. 2017

Society for Endocrinology Summer Studentship, Is there a gender paradox in skeletal muscle lipid storage?, Grant value (£): 1,000, Duration of research project: 10 weeks. 2017

Society for Endocrinology, Discovery of new members of the lipid droplet-protein interactome in human skeletal muscle and their role in the development of insulin resistance, Grant value (£): 9993, Duration of research project: 1 year. 2017

LJMU PhD Scholarship Scheme, High intensity interval training: moving away from the laboratory and towards community interventions and public health recommendations, Matthew Cocks, LJMU; Anton JM Wagenmakers, LJMU, Grant value (£): 58,206, Duration of research project: 3. 2016

LJMU PhD Scholarship Scheme, Why are women at lower risk of obesity-induced insulin resistance and type 2 diabetes than men?, Sam O Shepherd, LJMU; Matthew S Cocks, LJMU; Anton JM Wagenmakers, LJMU, Grant value (£): 58,206, Duration of research project: 3 years. 2015

Diabetes Research Wellness Foundation, Is high intensity interval training an efficient and effective form of exercise for people with type 1 diabetes?, Dr Sam Shepherd (PI), Co-investigators: Dr Matthew Cocks, Professor Anton Wagenmakers, Dr Rob Andrews (University of Bristol), Dr Parth Narendran (University of Birmingham)., Grant value (£): 19811. 2014

Conference presentation:

Hormone-sensitive lipase preferentially translocates to perilipin-5 associated lipid droplets during prolonged moderate intensity exercise in human skeletal muscle., FASEB: Lipid Droplets: Dynamic Organelles in Metabolism and Beyond, Denver, Colorado, Oral presentation. 2016

The association of SNAP23 with the mitochondrial network is reduced in skeletal muscle of obese sedentary females, 20th Annual Congress of the European College of Sport Science, Malmo, Sweden, Oral presentation. 2015

BODIPY reveals greater colocalisation of perilipin 2 and lipid droplets compared to oil red O, 19th Annual Congress of the European College of Sport Science, Amsterdam, Netherlands, Oral presentation. 2014

The association of SNAP23 with the mitochondrial network is reduced in the skeletal muscle of obese females, British Association for Research on Ageing Annual Conference, Liverpool, UK, Poster presentation. 2014

Association of SNAP23 with the mitochondrial network is reduced in skeletal muscle of obese females., European College of Sport Science, Bruges, Oral presentation. 2012

Visualising the subcellular distribution of SNAP23 in human skeletal muscle., International Biochemistry of Exercise Conference, Stockholm, Poster presentation. 2012

The association of SNAP23 with the mitochondrial network is reduced in the skeletal muscle of obese females’, International Symposium on Advances in Human Metabolism Research, Warwick, UK, Poster presentation. 2011

Visualisation of adipose triglyceride lipase and its activator CGI-58 in human skeletal muscle, 16th Annual Congress of the European College of Sport Science, Liverpool, UK, Oral presentation. 2011

Colocalisation of SNAP23 with mitochondria in skeletal muscle of physically active men, 15th Annual Congress of the European College of Sport Science, Antalya, Turkey, Oral presentation. 2010

The enzymes of intramuscular triglyceride synthesis exhibit fibre type specificity, Ageing, Sarcopenia and Exercise: From cell to whole body symposium, Birmingham, UK, Poster presentation. 2010

SNAP23 colocalises with mitochondria and not with lipid droplets in human skeletal muscle, UK Adipose Tissue Discussion Group, Alderley Park, UK, Poster presentation. 2009

The enzymes of intramuscular triglyceride synthesis exhibit fibre type specificity, 14th Annual Congress of the European College of Sport Science, Oslo, Norway, Poster presentation. 2009

Mitochondrial glycerol-3-phosphate acyltransferase and diacylglycerol acyltransferase distribution in human skeletal muscle, UK Adipose Tissue Discussion Group, Warwick, UK, Poster presentation. 2008

Teaching qualification:

PG Cert Learning and Teaching in Higher Education. 2015

Award:

British Society for Research in Ageing (BSRA) Poster Award for poster entitled ‘The association of SNAP23 with the mitochondrial network is reduced in the skeletal muscle of obese females’ at the BSRA Annual Meeting, Liverpool, UK. 2014

Young Investigator Award (Oral Presentation), Annual Congress of the European College of Sport Science, Bruges, Belgium, July 2012.. 2012

Young Investigator Award (Poster Presentation), Annual Congress of the European College of Sport Science, Oslo, Norway. 2009

Best Clinical Research Award, UK Adipose Tissue Discussion Group, sponsored by The Endocrinology Society. 2008