Liverpool Skylilne

Faculty of Science

Dr Nicola Dempster

Dr Nicola Dempster

Telephone: 0151 231 2323

Publications

Journal article

Brandt SD, Kavanagh PV, Westphal F, Stratford A, Odland AU, Klein AK, Dowling G, Dempster NM, Wallach J, Passie T, Halberstadt AL. 2020. Return of the lysergamides. Part VI: Analytical and behavioural characterization of 1-cyclopropanoyl-d-lysergic acid diethylamide (1CP-LSD) Drug Testing and Analysis, DOI Author Url Public Url

Al Groshi A, Jasim HA, Evans AR, Ismail FMD, Dempster NM, Nahar L, Sarker SD. 2019. Growth inhibitory activity of biflavonoids and diterpenoids from the leaves of the Libyan Juniperus phoenicea against human cancer cells Phytotherapy Research, 33 :2075-2080 DOI Author Url Publisher Url Public Url

Sadique M, Al-Nageim H, Atherton W, Seton L, Dempster N. 2019. Analytical investigation of hydration mechanism of a non-Portland binder with waste paper sludge ash Construction and Building Materials, 211 :80-87 DOI Author Url Publisher Url Public Url

Guetchueng ST, Nahar L, Ritchie KJ, Ismail FMD, Evans A, Sarker SD. 2019. Four new neo-clerodane diterpenes from the stem bark of Croton oligandrus. Natural Product Research, DOI Author Url Publisher Url Public Url

Ehtezazi T, Algellay M, Islam Y, Roberts M, Dempster NM, Sarker SD. 2018. The Application of 3D Printing in the Formulation of Multilayered Fast Dissolving Oral Films Journal of Pharmaceutical Sciences, 107 :1076-1085 DOI Author Url Publisher Url Public Url

Khan KM, Nahar L, Mannan A, Arfan M, Khan G, Al Groshi A, Evans A, Dempster NM, Ismail F, Sarker SD. 2018. Liquid chromatography mass spectrometry analysis and cytotoxicity of Asparagus adscendens roots against human cancer cell lines Pharmacognosy Magazine, 13 :890-894 DOI Author Url Publisher Url Public Url

Uddin S, Alnsour L, Segun P, Servi H, Celik S, Gokturk S, Al-Groshi A, Al-Majmaie S, Guetchueng ST, Nahar L, Dempster N, Ismail FMD, Ritchie KJ, Sarker SD. 2017. Flavonoids from two Turkish Centaurea species and their chemotaxonomic implications Trends in Phytochemical Research (TPR), 1 :243-248 Public Url

Hutcheon G, Dempster NM, Roberts M, Gaskell EE, Kianfar F. 2017. Lyophilised Biopolymer-Clay Hydrogels for Drug Delivery Journal of Novel Drug Research, 1 DOI Public Url

Fielding AJ, Evans PG, Alizadeh S, Bisby R, Drew MGB, Del Casino A, Dunn JF, Randle LE, Dempster NM, Nahar L, Sarker SD, Cantú Reinhard FG, de Visser SP, Dascombe MJ, Ismail FMD. 2017. Modulation of Antimalarial Activity at a Putative Bisquinoline Receptor in vivo Using Fluorinated Bisquinolines Chemistry - A European Journal, DOI Author Url Public Url

Yates S, Dempster N, Murphy M, Moore SA. 2017. Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography tandem mass spectrometry Rapid Communications in Mass Spectrometry, 31 :762-770 DOI Author Url Public Url

Khan KM, Nahar L, Al-Groshi A, Zavoianu AG, Evans A, Dempster NM, Wansi JD, Ismail FMD, Mannan A, Sarker SD. 2016. Cytotoxicity of the Roots of Trillium govanianum Against Breast (MCF7), Liver (HepG2), Lung (A549) and Urinary Bladder (EJ138) Carcinoma Cells Phytotherapy Research, 30 :1716-1720 DOI Author Url Public Url

Khan KM, Nahar L, Evans A, Ismail FMD, Dempster N, Al-Groshi A, Zazoianu AG, Wansi JD, Sarker SD. 2016. Evaluation of cytotoxicity of Trillium govanianum (Melanthiaceae) Phytotherapy Research, Public Url

Lambert DJ, Parikh N, Messham SJ, Edwards G, Hieu VT, Dempster NM, Drew MGB, Nahar L, Sarker SD, Ismail FMD. 2015. One-pot synthesis and negative ion mass spectrometric investigation of a densely functionalized cinnoline TETRAHEDRON LETTERS, 56 :6980-6983 DOI Author Url

Wallach J, Colestock T, Cicali B, Elliott SP, Kavanagh PV, Adejare A, Dempster NM, Brandt SD. 2015. Syntheses and analytical characterizations of N-alkyl-arylcyclohexylamines Drug Testing and Analysis, DOI Author Url Publisher Url Public Url

Wallach J , Kavanagh PV , McLaughlin G , Morris N , Power JD , Elliott SP , Mercier MS , Lodge D , Morris H , Dempster NM , Brandt SD . 2015. Preparation and characterization of the ‘research chemical’ diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers Drug Testing and Analysis, 7 :358-367 DOI Author Url Publisher Url

Wallach J, Kavanagh PV, Mclaughlin G, Morris N, Power JD, Elliott SP, Mercier MS, Lodge D, Morris H, Dempster NM, Brandt SD. 2015. Preparation and characterization of the 'research chemical' diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers Drug Testing and Analysis, 7 :358-367 DOI Public Url

Brandt SD, Elliott SP, Kavanagh PV, Dempster NM, Meyer MR, Maurer HH, Nichols DE. 2015. Analytical characterization of bioactive N-benzyl-substituted phenethylamines and 5-methoxytryptamines Rapid Communications in Mass Spectrometry, 29 :573-584 DOI Author Url Publisher Url Public Url

Bobrovs R, Seton L, Dempster N. 2015. The reluctant polymorph: investigation into the effect of self-association on the solvent mediated phase transformation and nucleation of theophylline CrystEngComm, 17 :5237-5251 DOI Author Url Publisher Url Public Url

Ehtezazi T, Dempster NM, Martin GD, Hoath SD, Hutchings IM. 2014. Development of High-Throughput Glass Inkjet Devices for Pharmaceutical Applications JOURNAL OF PHARMACEUTICAL SCIENCES, 103 :3733-3742 DOI Author Url Public Url

Ehtezazi T, Dempster NM, Martin GD, Hoath SD, Hutchings IM. 2014. Development of high-throughput glass inkjet devices for pharmaceutical applications Journal of Pharmaceutical Sciences, 103 :3733-3742 DOI

Brandt SD, Dempster NM, Baumann MH, Partilla JS, Kavanagh PV, Power JD, Talbot B, Twamley B, O'Brien J, Mahony O, Elliott SP, Archer RP, Patrick J, Singh K, Cosbey SH. 2014. Characterization of a novel and potentially lethal designer drug (±)-cis-para-methyl-4-methylaminorex (4,4'-DMAR, or 'Serotoni') Drug Testing and Analysis, 6 :684-695 DOI Author Url Publisher Url

Gaujac A, Ford JL, Dempster NM, de Andrade JB, Brandt SD. 2013. Investigations into the polymorphic properties of N,N-dimethyltryptamine by X-ray diffraction and differential scanning calorimetry Microchemical Journal, 110 :146-157 DOI Author Url

Sadique M, Al-Nageim H, Atherton W, Seton L, Dempster N. 2013. Mechano-chemical activation of high-Ca fly ash by cement free blending and gypsum aided grinding Construction and Building Materials, 43 :480-489 DOI Author Url

Al-Nageim H, Sadique M, Atherton W, Seton L, Dempster N. 2013. Strength development of optimised cementitious materials containing fly ashes and silica fume ADVANCES IN CEMENT RESEARCH, 25 :90-97 DOI Author Url

Sadique M, Al-Nageim H, Atherton W, Seton L, Dempster N. 2012. A laboratory study for full cement replacement by fly ash and silica fume MAGAZINE OF CONCRETE RESEARCH, 64 :1135-1142 DOI Author Url

Al-Busaltan S, Al Nageim H, Atherton W, Sharples G, Seton L, Dempster N. 2012. Use of sem and XRD for characterisation the improvement in CMEM'S engineering properties 34th International Conference on Cement Microscopy 2012, :11-22

Sadique M, Al-Nageim H, Atherton W, Seton L, Dempster N. 2012. Identification of mineralogical changes towards advanced reactivity of fly ashes for mechanical activation 34th International Conference on Cement Microscopy 2012, :336-349

Sadique M, Al Nageim H, Atherton W, Seton L, Dempster N. 2012. A new composite cementitious material for construction CONSTRUCTION AND BUILDING MATERIALS, 35 :846-855 DOI Author Url

Brandt SD, Tirunarayanapuram SS, Freeman S, Dempster N, Barker SA, Daley PF, Cozzi NV, Martins CPB. 2008. Microwave-accelerated synthesis of psychoactive deuterated N,N-dialkylated-[alpha,alpha,beta,beta-d(4)]-tryptamines JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 51 :423-429 DOI Author Url

Brandt SD, Martins CPB, Freeman S, Dempster N, Riby PG, Gartz J, Alder JF. 2008. Halogenated solvent interactions with N,N-dimethyltryptamine: formation of quaternary ammonium salts and their artificially induced rearrangements during analysis. Forensic Sci Int, 178 :162-170 DOI Author Url

Brandt SD, Martins CPB, Freeman S, Dempster N, Wainwright M, Riby PG, Alder JF. 2008. N,N-Dimethyltryptamine and dichloromethane: rearrangement of quaternary ammonium salt product during GC-EI and CI-MS-MS analysis. J Pharm Biomed Anal, 47 :207-212 DOI Author Url

Gaujac A, Dempster N, Navickiene S, Brandt SD, de Andrade JB. Determination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometry. Talanta, 106 :394-398 DOI Author Url Publisher Url

Brandt SD, Tearavarich R, Dempster N, Cozzi NV, Daley PF. Synthesis and characterization of 5-methoxy-2-methyl-N,N-dialkylated tryptamines. Drug Test Anal, 4 :24-32 DOI Author Url

Wainwright M, Shah A, Meegan K, Loughran C, Smith A, Valli N, Dempster N. Phenothiazinium-fluoroquinolone drug conjugates. Int J Antimicrob Agents, 35 :405-409 DOI Author Url

lambert D, Parikh N, Messham SJ, Edwards G, Truong HV, Dempster NM, Drew MGB, Nahar L, Sarker SD, Ismail FMD. One-pot synthesis and negative ion mass spectrometric investigation of a densely functionalized cinnoline, 3-amino-5,7,8-trichloro-6-hydroxycinnoline-4-carbonitrile tetrahedron Letters, Public Url

Guetchueng ST, Nahar L, Ritchie KJ, Ismail FMD, Dempster NM, Sarker SD. Justicialosides A and B, two new flavone glycosides from the leaves of Ruspolia hypocrateriformis (Vahl) Milne-Redh. (Acanthaceae) Phytochemistry Letters, 31 :101-103 DOI Author Url Publisher Url Public Url

Al Nageim H, Al-Khuzai A, Draker J, Linda S, Dempster N. XRDF, SEM and Compressive Strength Properties of a New Alkali Activated Fly Ash Concrete Mortar Seton L. Advances and Challenges in Structural Engineering, :370-380 DOI

Guetchueng ST, Nahar L, Ritchie KJ, Ismail FMD, Dempster NM, Nnanga EN, Sarker S. Phenolic compounds from the leaves and stem bark of Pseudospondias microcarpa (A. Rich.) Engl. (Anacardiaceae) Biochemical Systematics and Ecology, DOI Author Url Public Url

Conference publication

Al Groshi A, Evans A, Jasim H, Ismail F, Dempster N, Nahar L, Sarker S. 2020. In vitro cytotoxicity of Arbutus pavarii against human cancer cell lines T20 PSE Conference :53-53

Al Groshi A, Evans A, Jasim HA, Ismail FMD, Dempster NM, Nahar L, Sarker SD. 2019. In vitro cytotoxicity of Asphodelus aestivus against human cancer cell lines PSE-YSM

Al Nageim H, Al-Khuzai A, Draker J, Croft J, Seton L, Dempster N. 2018. XRDF, SEM and Compressive Strength Properties of a New Alkali Activated Fly Ash Concrete Mortar Advances and Challenges in Structural Engineering, International Congress and Exhibition on Sustainable Civil Infrastructures: Innovative Infrastructure Geotechnology, GeoMEast 2018 :370-380 DOI

Al Groshi A, Evans AR, Ismail FMD, Dempster NM, Nahar L, Sarker SD. 2018. In vitro cytotoxicity of Ruta chalepensis against human cancer cell lines PSE-YSM2018 Liverpool Conference abstract,

Al-Groshi A, Evans AR, Ismail FMD, Dempster NM, Nahar L, Sarker SD. 2018. In vitro cytotoxicity of Ruta chalepensis against human cancer cell lines PSE-YSM

Al-Groshi A, Evans AR, Ismail F, Jasim HA, Dempster N, Nahar L, Sarker S. 2018. Bioassay-guided isolation of cytotoxic compounds from the Libyan plant Juniperus Phoenicea Phytopharm 22nd International Congress

Mehan A, Migaz N, Parikh N, Truong HV, Lambert DJ, Messham SJ, McKay J, Mahamed N, Brooks S, Lloyd M, Morris H, Dempster NM, Randle LE, Burrell HE, Sarker SD, Nahar L, Evans PG, Dascombe MJ, Strasnov N, Edwards G, Drew MGB, Barran P, Ismail FMD. 2015. Purpurogallin-A heme binding component of oak galls BMSS Annual Meeting: Birmingham Publisher Url Public Url

Yaqoob N, Dempster N, Reed CJ, Lock EA. 2009. Sex differences in formic aciduria in Fischer 344 (F-344) rats and dose response in male F-344 rats exposed orally to trichloroethylene TOXICOLOGY, Annual Congress of the British-Toxicological-Society 262 :24-25 DOI Author Url

Ismail FMD, Dempster NM, Ford JL. 2009. Rapid and efficient isolation of cryptolepine from Cryptolepis sanguinolenta using focused microwave extraction methods: a haem-binding antimalarial JOURNAL OF PHARMACY AND PHARMACOLOGY, 61 :A9-A10 Author Url

Ismail FMD, Cox AH, Dempster NM, Ford JL, Dascombe JL, Drew MGB. LC-MS & DFT Investigations of Cryptolepis Sanginolenta Root Extracts Journal of Pharmacy and Pharmacology, UK-PharmSci 2010, The Science of Medicines 62 :1489-1490 Author Url Publisher Url

Other

Horgan MJ, Leanca MA, Hill CE, Guetchueng ST, Drew MGB, Dempster NM, Nahar L, Sarker SD, Reinhard FGC, de Visser SP, Dascombe MJ, Fielding AJ, Ismail FMD. 2018. Black pepper as a source for new antimalarials

Al-Majmaie S, Nahar L, Sharples GP, Ismail FMD, Dempster NM, Sarker SD. 2018. In vitro antimicrobial activity of Ruta chalepensis growing in Iraq PSE-YSM2018 Liverpool Conference Abstract,