Liverpool Skylilne

Natural Sciences and Psychology

Dr Davide Bruno

Dr Davide Bruno

Telephone: 0151 904 6320

website
ORCID

Biography

I was born in Italy and graduated in Psychology from the University of Parma, then obtained a PhD from Keele University (2007). After positions at the University of Southampton, the University of Massachusetts, Amherst, the Nathan Kline Institute, New York University, and Liverpool Hope University, I joined Liverpool John Moores University as a Senior Lecturer.

My interests are, broadly, memory, ageing and dementia.

You can also find me at: http://dbrunolab.wordpress.com/

Publications

Highlighted publications

Bruno D, Grothe MJ, Nierenberg J, Zetterberg H, Blennow K, Teipel SJ, Pomara N. 2015. A study on the specificity of the association between hippocampal volume and delayed primacy performance in cognitively intact elderly individuals NEUROPSYCHOLOGIA, 69 :1-8 DOI Author Url Public Url

Bruno D, Grothe MJ, Nierenberg J, Sidtis JJ, Teipel SJ, Pomara N. Output order and variability in free recall are linked to cognitive ability and hippocampal volume in elderly individuals. Neuropsychologia, 80 :126-132 DOI Author Url Public Url

Journal article

Talamonti D, Koscik R, Johnson S, Bruno D. 2019. Predicting Early Mild Cognitive Impairment With Free Recall: The Primacy of Primacy. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, DOI Author Url Public Url

Bruno D, Gleason C, Koscik R, Pomara N, Zetterberg H, Blennow K, Johnson S. 2019. The recency ratio is related to CSF Amyloid Beta 1-42 levels in MCI-AD International Journal of Geriatric Psychiatry, 34 :415-419 DOI Author Url Public Url

Bruno D, Koscik R, Woodard J, Pomara N, Johnson S. 2018. The recency ratio as predictor of early MCI International Psychogeriatrics, 30 :1883-1888 DOI Author Url Public Url

Couth S, Stringer G, Leroi I, Sutcliffe A, Gledson A, Bruno D, McDonald K, Montaldi D, Poliakoff E, Rust J, Thompson J, Brown L. 2017. Which computer-use behaviours are most indicative of cognitive decline? Insights from an expert reference group Health Informatics Journal, DOI Author Url Publisher Url Public Url

Clark DPA, Bruno D. 2016. Fit to last: Exploring the longevity of the survival processing effect QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY, 69 :1164-1178 DOI Author Url Public Url

Bruno D, Grothe MJ, Nierenberg J, Zetterberg H, Blennow K, Teipel SJ, Pomara N. 2015. A study on the specificity of the association between hippocampal volume and delayed primacy performance in cognitively intact elderly individuals NEUROPSYCHOLOGIA, 69 :1-8 DOI Author Url Public Url

Pomara N, Lee SH, Bruno D, Silber T, Greenblatt DJ, Petkova E, Sidtis JJ. 2015. Adverse performance effects of acute lorazepam administration in elderly long-term users: Pharmacokinetic and clinical predictors PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 56 :129-135 DOI Author Url Public Url

Bruno D, Grothe MJ, Nierenberg J, Teipel SJ, Zetterberg H, Blennow K, Pomara N. 2015. The relationship between cerebrospinal fluid tau markers, hippocampal volume, and delayed primacy performance in cognitively intact elderly individuals Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 1 :81-86 DOI Author Url Public Url

Young JJ, Bruno D, Pomara N. 2014. A review of the relationship between proinflammatory cytokines and major depressive disorder JOURNAL OF AFFECTIVE DISORDERS, 169 :15-20 DOI Author Url Public Url

Bruno D, Brown AD, Kapucu A, Marmar CR, Pomara N. 2014. Cognitive Reserve and Emotional Stimuli in Older Individuals: Level of Education Moderates the Age-Related Positivity Effect EXPERIMENTAL AGING RESEARCH, 40 :208-223 DOI Author Url Public Url

Lyons M, Lynch A, Brewer G, Bruno D. 2014. Detection of Sexual Orientation ("Gaydar") by Homosexual and Heterosexual Women ARCHIVES OF SEXUAL BEHAVIOR, 43 :345-352 DOI Author Url

Bruno D, Lyons M, Brewer G. 2014. Response to Bayesian Advice for Gaydar-Based Picking Up: Commentary on Lyons, Lynch, Brewer, and Bruno (2013) by Ploderl ARCHIVES OF SEXUAL BEHAVIOR, 43 :11-12 DOI Author Url

Lyons M, Healy N, Bruno D. 2013. It takes one to know one: Relationship between lie detection and psychopathy PERSONALITY AND INDIVIDUAL DIFFERENCES, 55 :676-679 DOI Author Url Public Url

Bruno D, Reiss PT, Petkova E, Sidtis JJ, Pomara N. 2013. Decreased Recall of Primacy Words Predicts Cognitive Decline ARCHIVES OF CLINICAL NEUROPSYCHOLOGY, 28 :95-103 DOI Author Url Public Url

Pillai A, Bruno D, Sarreal AS, Hernando RT, Saint-Louis LA, Nierenberg J, Ginsberg SD, Pomara N, Mehta PD, Zetterberg H, Blennow K, Buckley PF. 2012. Plasma BDNF Levels Vary in Relation to Body Weight in Females PLOS ONE, 7 DOI Author Url Public Url

Bruno D, Pomara N, Nierenberg J, Ritchie JC, Lutz MW, Zetterberg H, Blennow K. 2012. Levels of cerebrospinal fluid neurofilament light protein in healthy elderly vary as a function of TOMM40 variants EXPERIMENTAL GERONTOLOGY, 47 :347-352 DOI Author Url

Bruno D, Nierenberg JJ, Ritchie JC, Lutz MW, Pomara N. 2012. Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants PSYCHONEUROENDOCRINOLOGY, 37 :366-371 DOI Author Url

Bruno D. 2012. Predictions in the Brain: Using our Past to Generate a Future MEMORY STUDIES, 5 :96-97 DOI Author Url

Pomara N, Bruno D. 2011. Potential effects of the APOE e2 allele and of family history of Alzheimer's disease on brain amyloid-beta in normal elderly PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108 :E1007-E1007 DOI Author Url

Pomara N, Bruno D, Sidtis JJ, Lutz MW, Greenblatt DJ, Saunders AM, Roses AD. 2011. Translocase of Outer Mitochondrial Membrane 40 Homolog (TOMM40) Poly-T Length Modulates Lorazepam-Related Cognitive Toxicity in Healthy APOE epsilon 4-Negative Elderly JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 31 :544-546 DOI Author Url

Pomara N, Bruno D, Nierenberg JJ, Sidtis JJ, Martiniuk FT, Mehta PD, Zetterberg H, Blennow K. 2011. TOMM40 poly-T Variants and Cerebrospinal Fluid Amyloid Beta Levels in the Elderly NEUROCHEMICAL RESEARCH, 36 :1124-1128 DOI Author Url

Pomara N, Bruno D. 2011. Lower plasma β-amyloid levels are associated with moderately greater rate of cognitive decline among older people without dementia Evidence-Based Mental Health, 14 :41 DOI Author Url

Pomara N, Bruno D, Sidtis JJ. 2011. Plasma beta-Amyloid Level, Cognitive Reserve, and Cognitive Decline JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 305 :1655-1655 DOI Author Url

Okereke OI, Selkoe DJ, Grodstein F. 2011. Plasma beta-Amyloid Level, Cognitive Reserve, and Cognitive Decline JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 305 :1655-1655 DOI Author Url

Bruno D, Rutherford A. 2010. How many response options? A study of remember-know testing procedures ACTA PSYCHOLOGICA, 134 :125-129 DOI Author Url

Higham PA, Bruno D, Perfect TJ. 2010. Effects of study list composition on the word frequency effect and metacognitive attributions in recognition memory MEMORY, 18 :883-899 DOI Author Url

Bruno D, Grothe MJ, Nierenberg J, Sidtis JJ, Teipel SJ, Pomara N. Output order and variability in free recall are linked to cognitive ability and hippocampal volume in elderly individuals. Neuropsychologia, 80 :126-132 DOI Author Url Public Url

White C, Kapucu A, Bruno D, Rotello C, Ratcliff R. Memory bias for negative emotional words in recognition memory is driven by effects of category membership Cognition and Emotion, 28 :867-880 DOI Author Url Public Url

Pomara N, Bruno D, Sarreal A, Hernando R, Nierenberg J, Petkova E, Sidtis J, Wisniewski T, Mehta P, Pratico D, Zetterberg H, Blennow K. Lower CSF Amyloid Beta Peptides and Higher F2-Isoprostanes in Cognitively Intact Elderly Individuals With Major Depressive Disorder American Journal of Psychiatry, 169 :523-530 DOI Author Url

Bruno D, Higham PA, Perfect TJ. Global subjective memorability and the strength-based mirror effect in recognition memory Memory and Cognition, 37 :807-818 DOI Author Url

Higham PA, Perfect T, Bruno D. Investigating strength and frequency effects in recognition memory using type-2 signal detection theory Journal of Experimental Psychology: Learning, Memory, and Cognition, 35 :57-80 DOI Author Url

Teipel S, Bruno D, Grothe M, Nierenberg J, Pomara N. Hippocampus and basal forebrain volumes modulate effects of anticholinergic treatment on delayed recall in healthy older adults Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 1 :216-219 DOI Author Url Public Url

Hashimoto K, Bruno D, Pomara N, Nierenberg J, Marmar C, Zetterberg H, Blennow K. Abnormality in glutamine-glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study Translational Psychiatry, DOI Author Url Public Url

Kasper E, Brueggen K, Grothe M, Bruno D, Pomara N, Unterauer E, Duering M, Ewers M, Teipel S, Buerger K. Neuronal correlates of serial position performance in amnestic MCI Neuropsychology, DOI Author Url Public Url

Young J, Silber T, Bruno D, Galatzer-Levy I, Pomara N, Marmar C. Is there Progress? An Overview of Select Biomarker Candidates for Major Depressive Disorder Frontiers in Psychiatry, DOI Author Url Public Url

Bruno D, Reichert, C , Pomara, N . The recency ratio as an index of cognitive performance and decline in elderly individuals Journal of Clinical and Experimental Neuropsychology, DOI Author Url Public Url

Bruno D, Ciarleglio A, Grothe M, Nierenberg J, Bachman A, Teipel S, Petkova E, Ardekani B, Pomara N. Hippocampal volume and integrity as predictors of cognitive decline in intact elderly Neuroreport, DOI Author Url Public Url

Pomara N, Bruno D, Osorio R, Reichert C, Nierenberg J, Sarreal A, Hernando R, Marmar C, Wisniewski T, Zetterberg H, Blennow K. State-dependent alterations in CSF Abeta42 levels in cognitively intact elderly with late life major depression Neuroreport, DOI Author Url Public Url

Brueggen K, Kasper E, Dyrba M, Bruno D, Pomara N, Ewers M, Duering M, Buerger K, Teipel S. The Primacy Effect in Amnestic Mild Cognitive Impairment: Associations with Hippocampal Functional Connectivity Frontiers in Aging Neuroscience, DOI Author Url Public Url

Bruno D, Nierenberg J, Cooper T, Marmar C, Zetterberg H, Blennow K, Hashimoto K, Pomara N. The recency ratio is associated with reduced CSF glutamate in late-life depression Neurobiology of Learning and Memory, DOI Author Url Public Url

Gollan JK, Dong H, Bruno D, Nierenberg J, Nobrega JN, Grothe MJ, Pollock BG, Marmar CR, Teipel S, Csernansky JG, Pomara N. Basal Forebrain Mediated Increase in Brain CRF is Associated with Increased Cholinergic Tone and Depression 'Psychiatry Research: Neuroimaging, DOI Author Url Public Url

Hashimoto K, Ishima T, Sato Y, Bruno D, Nierenberg J, Marmar CR, Zetterberg H, Blennow K, Pomara N. Increased levels of ascorbic acid in the cerebrospinal fluid of cognitively intact patients with major depression: a preliminary study Scientific Reports, DOI Author Url Publisher Url Public Url

Pomara N, Bruno D. Pathological increases in neuronal hyperactivity in selective cholinergic and noradrenergic pathways may limit the efficacy of Aβ-based interventions in MCI and Alzheimer’s disease JAD Reports, DOI Author Url Public Url

Pillai A, Bruno D, Nierenberg J, Pandya C, Feng T, Reichert C, Ramos-Cejudo J, Osorio R, Zetterberg H, Blennow K, Pomara N. Complement component 3 levels in the cerebrospinal fluid of Cognitively Intact Elderly Individuals with Major Depressive Disorder Biomarkers in Neuropsychiatry, :100007-100007 DOI Public Url

Conference publication

Pomara N, Bruno D, Nierenberg J, Reichert C, Fu M, Zetterberg H, Blennow K. 2019. CSF butyrylcholinesterase and acetyl-cholinesterase activity and their relationship to pro-inflammatory cytokines in late-life major depression EUROPEAN NEUROPSYCHOPHARMACOLOGY, 31st Congress of the European-College-of-Neuropsychopharmacology (ECNP) 29 :S79-S80 DOI Author Url

Pomara N, Bruno D, Nierenberg J, Zetterberg H, Blennow K, Heslegrave A, Foiani M. 2017. Reduction in CSF sTREM2, a Biomarker of Microglia Activation, in Elderly Depressives NEUROPSYCHOPHARMACOLOGY, 56th Annual Meeting of the American-College-of-Neuropsychopharmacology (ACNP) and Cognitive-Neuroscience-Society 42 :S409-S409 Author Url

Pomara N, Nierenberg J, Bruno D, Reichert C, Osorio R, Sarreal A, Hernando R, Marmar C, Wisniewski T, Zetterberg H, Blennow K. 2016. Selective and State-Dependent Changes in CSF Abeta42 Levels in Cognitively-Intact Elderly With Late Life Major Depression NEUROPSYCHOPHARMACOLOGY, 41 :S544-S544 Author Url

Pomara N, Bruno D, Ciarleglio A, Constantine A, Reichert C, Petkova E, Zetterberg H, Blennow K. 2015. Biomarkers of Cognitive Decline in Elderly Depressives NEUROPSYCHOPHARMACOLOGY, 54th Annual Meeting of the American-College-of-Neuropsychopharmacology (ACNP) 40 :S327-S327 Author Url

Pomara N, Bruno D, Reichert C, Nierenberg J, Sidtis JJ, Martiniuk FT, Zetterberg H, Blennow K. 2013. Chemokine-specific Relationships to AD Biomarkers in CSF in Healthy Older Adults NEUROPSYCHOPHARMACOLOGY, 38 :S164-S164 Author Url

Editorial/letter to the editor

Rutherford A, Stewart W, Bruno D. 2017. Heading for trouble: is dementia a game changer for football? British Journal of Sports Medicine, 53 DOI Author Url Public Url

Tawfik H, Bruno D. 2016. Editorial International Journal of Medical Informatics, 91 DOI

Tawfik H, Bruno D. Editorial International Journal of Medical Informatics, 91 :74-74 DOI

Pomara N, Bruno D. Major depression may lead to elevations in potentially neurotoxic amyloid beta species independently of Alzheimer’s disease American Journal of Geriatric Psychiatry, DOI Author Url

Pomara N, Bruno D. Basal Forebrain Resting Functional Activity Associated with Brain Amyloid-β Burden in ε4 Carriers and Older Women: Possible Implications for Baseline Cognition and Response to Amyloid-β-based Preventive Trials Radiology, DOI Author Url

Bruno D, Busse' C, Cagnin A. Effective discrimination with the recency ratio between Alzheimer’s disease and dementia with Lewy bodies Journal of Alzheimer's Disease,

Book

Bruno D. 2015. The preservation of memory :1-231 9781138840188 DOI

Chapters

Bruno D, Rutherford A. The effects of normal and pathological aging on memory The Preservation of Memory: Theory and Practice for Clinical and Non-Clinical Populations DOI

Bruno D, Renner D, Barrett-Baxendale M, Reid D, Tawfik H. Augmenting familiar appliances to assist people living with dementia The Preservation of Memory: Theory and Practice for Clinical and Non-Clinical Populations DOI

Bruno D, Rutherford A, Markopoulos G, Van Den Bos M. Long-term memory: encoding to retrieval Cognitive Psychology

Engagement & Impact

Other invited event:

What does the serial position curve tell us about dementia risk?, Liverpool Hope University, Nov 2018, External Speaker: What does the serial position curve tell us about dementia risk? Department of Psychology, Liverpool Hope University, England, UK.. 2018

BPS Cognitive Conference, Liverpool, Proponent and Chair of Symposium on Cognitive Ageing.. 2018

6th International Conference on Memory, Budapest, Hungary, Symposium on “Memory Preservation and Decline”. 2016

BPS General Conference, Nottingham, UK, Invited to speak at Symposium. Talk title: "A longitudinal study of plasma Amyloid-β levels in late-life major depression". 2016

Ageing and memory: Tracking change to predict decline, Keele University, Invited talk. 2014

Award:

Developing and validating a survey method for determining amount of football heading done over a football career Grant – Co-Investigator: 2018 - ¥997,001, The Univers Foundation (Japan). 2018

Best Poster: Second Prize at the 2nd Annual NYU Center of Excellence on Brain Aging Research Day. 2011

Experimental Psychological Society: Grindley Grant. 2006

Public engagement:

Salford University, North West Dementia ARUK Public Engagement, Talk and organisation committee, General public, experts in dementia, researcehrs, people with dementia, Representative for LJMU. 2017

Blacon, Cheshire, Dementia talks/meetings at Vintage Blacon (Community Group), Blacon, Chester, Public talks, General public, stakeholders, charities, community support, Speaker. 2013

Teaching qualification:

Higher Education Associate Teacher Certificate. 2004

Media Coverage:

http://blogs.bmj.com/bjsm/2017/02/15/heading-trouble-dementia-game-changer-football/, Editorial on British Medical Journal Blogs - British Journal of Sport Medicine blog. Title: Heading for trouble: is dementia a game changer for football?.

http://www.livescience.com/27735-words-list-mental-decline.html, Forgetting first words on a list may signal mental decline, written by Rachael Rettner. Based on Bruno et al. (2013). Archives of Clinical Neuropsychology. Published on Fox News and other outlets..

http://www.medscape.com/viewarticle/761557, Alzheimer’s biomarkers linked to major depression, written by Deborah Brauser. Based on Pomara, Bruno et al. (2012). American Journal of Psychiatry. Published on Medscape Today News.

https://www.psychologytoday.com/blog/strictly-casual/201403/are-lesbians-less-casual-sex-hetero-women, Are lesbians less into casual sex than hetero women?, written by Zhana Vrangalova. Based on Lyons, …, Bruno (2014). Archives of Sexual Behavior. Published on Psychology Today..

Fellowships:

Fellow of the Higher Education Academy, Higher Education Academy.

Editorial boards:

Journal of Neuropsychology, Associated Editor.

External collaboration:

Keele University, Dr Andrew Rutherford.

Nathan Kline Institute and New York University, Dr Nunzio Pomara.

University of Gothenburg, Dr henrik Zetterberg & Dr Kaj Blennow.

University of Manchester, Dr Iracema Leroy.

University of Padova, Annachiara Cagnin.

University of Rostock, Dr Stefan Teipel.

University of Wisconsin, Madison, Dr Rebecca Koscik & Dr Sterling Johnson (5)..

Conference organisation:

Symposium on “Health Informatics for Active Ageing and People with Dementia”. Liverpool Hope University, July 2014.