Liverpool Skylilne

Natural Sciences and Psychology

Dr Fatima Perez De Heredia Benedicte

Dr Fatima Perez De Heredia Benedicte

Telephone: 0151 231 2003

ORCID

Biography

My research interests are human nutrition, adipose tissue physiology and obesity, and in particular the study of the relationships between obesity, nutritional status, inflammation and immunity.

One of my main lines of research, human nutrition, has allowed me to participate in different population-based studies, in order to assess the nutritional status of subjects and to analyse and identify the relationships between nutritional habits, lifestyle patterns and a wide battery of health indicators, including genetic, inflammatory and immune biomarkers. I have also been involved in the PRONAOS Project, an initiative that brought together scientific research and industry for developing food products for weight control and obesity prevention (www.proyectopronaos.es).

My other main line of work is the biology of adipose tissue, and how certain stimuli (e.g., high-fat diets, hypoxia, hormones) can affect adipose tissue physiology and adipocyte function, and thus contribute to the development of certain conditions, such as inflammation or insulin resistance.

Languages

Spanish; Castilian
English
German
French

Degrees

2000, University of Murcia, Spain, BSc Biological Sciences

Postgraduate training

Postgraduate Certificate in Higher Education, United Kingdom, Liverpool John Moores University, ? - 2017
PhD Biology, Spain, University of Murcia, ? - 2007
Post-graduate Certificate in Education, Spain, University of Murcia, ? - 2003
Suficiencia Investigadora (MPhil/MSc equivalent) Biomedical Experimental Sciences, Spain, University of Murcia, ? - 2002

Publications

Highlighted publications

Gheorghe A, Pérez de Heredia F, Hunsche C, Redondo N, Díaz LE, Hernández O, Marcos A, De la Fuente M. 2017. Oxidative stress and immunosenescence in spleen of obese mice can be reversed by 2-hydroxyoleic acid. Exp Physiol, DOI Author Url Public Url

Perez-de-Heredia F, Gomez-Martinez S, Diaz L-E, Veses AM, Nova E, Warnberg J, Huybrechts I, Vyncke K, Androutsos O, Ferrari M, Palacios G, Wastlund A, Kovacs E, Gottrand F, Gonzalez-Gross M, Castillo MJ, Sjostrom M, Manios Y, Kafatos A, Molnar D, Widhalm K, Moreno LA, Marcos A. 2015. Influence of sex, age, pubertal maturation and body mass index on circulating white blood cell counts in healthy European adolescents-the HELENA study EUROPEAN JOURNAL OF PEDIATRICS, 174 :999-1014 DOI Author Url Public Url

de Heredia FP, Gómez-Martínez S, Marcos A. Obesity, inflammation and the immune system. Proc Nutr Soc, 71 :332-338 DOI Author Url

Perez De Heredia Benedicte F, Garaulet M, Gómez-Martínez S, Díaz LE, Wärnberg J, Androutsos O, Michels N, Breidenassel C, Cuenca-García M, Huybrechts I, Gottrand F, Ferrari M, Santaliestra-Pasías AM, Kafatos A, Molnár D, Sjöstrom M, Widhalm K, Moreno LA, Marcos A, HELENA Study Group . Self-reported sleep duration, white blood cell counts and cytokine profiles in European adolescents. The HELENA Study Sleep Medicine, DOI Author Url

Warburton J, Perez De Heredia Benedicte F. The role of immune cells in adipose tissue Calder P, Kulkarni A. Nutrition, Immunity and Infection :43-56 Taylor & Francis 9781482253979 DOI

Nova E, Perez De Heredia Benedicte F, Gómez-Martínez S, Marcos A. The role of probiotics on the microbiota: effect on obesity NUTRITION IN CLINICAL PRACTICE, 31 :387-400 DOI Author Url

Perez De Heredia Benedicte F, Redondo N, Gheorghe A, Diaz LE, Baccan GC, de la Fuente M, Marcos A. 2-OHOA supplementation reduced adiposity and improved cardiometabolic risk to a greater extent than n-3 PUFA in obese mice Obesity Research and Clinical Practice, Public Url

Conference publication

Perez-Heredia F. 2018. Adipose Tissue as an Inflammatory Focus ANNALS OF NUTRITION AND METABOLISM, 73 :193-194 Author Url

Warburton J, Perez De Heredia Benedicte F, George K, Marcos A, Gomez S, Zapatera B. 2015. Comparison of three commonly used indicators of abdominal obesity in estimating prevalence and metabolic risk ANNALS OF NUTRITION AND METABOLISM, 12th European Nutrition Conference 67 :260-260 Author Url

Vyncke K, Dumont J, Dallongeville J, Meirhaeghe A, Huybrechts I, Van Winckel M, Gonzalez-Gross M, Cuenca-Garcia M, de Heredia FP, Stehle P, Libuda L, Moreno L, Manios Y, Widhalm K, Kafatos A, Molnar D, de Henauw S. 2013. DIET AND PHYSICAL ACTIVITY INTERACT WITH THE 514C/T POLYMORPHISM IN HEPATIC LIPASE GENE ON SERUM LIPID AND FATTY ACID CONCENTRATIONS ANNALS OF NUTRITION AND METABOLISM, 63 :349-349 Author Url

Veses AM, Gomez-Martinez S, Perez De Heredia F, Zapatera B, Veiga OL, Marcos A. 2013. Differences on lymphocyte subset counts according to the degree of overweight-obesity in adolescents from Madrid. The AFINOS Study PROCEEDINGS OF THE NUTRITION SOCIETY, 72 :E68-E68 DOI Author Url

Perez de Heredia F, Gomez-Martinez S, Diaz LE, Veses AM, Androutsos O, Dallongeville J, De Henauw S, Censi L, Moreno LA, Palacios G, Marcos A. 2013. Lymphocyte subsets, anthropometric measurements and body composition in European adolescents. The HELENA Study PROCEEDINGS OF THE NUTRITION SOCIETY, 72 :E19-E19 DOI Author Url

Perez de Heredia F, Diaz LE, Gomez-Martinez S, Androutsos O, Dallongeville J, DeHenauw S, Ferrari M, Moreno LA, Palacios G, Marcos A. 2013. White blood cell count is associated with features of the metabolic syndrome in European adolescents. The HELENA Study PROCEEDINGS OF THE NUTRITION SOCIETY, 72 :E17-E17 DOI Author Url

Perez de Heredia F, Garaulet M, Gomez-Martinez S, Diaz LE, Veses AM, Breidenassel C, Ferrari M, Gottrand F, Kafatos A, Manios Y, Molnar D, Moreno LA, Sjostrom M, Widhalm K, Marcos A. 2013. Sleep duration and lymphocyte subsets profile in European adolescents. The HELENA Study PROCEEDINGS OF THE NUTRITION SOCIETY, 72 :E18-E18 DOI Author Url

Hernandez A, Pozo-Rubio T, Gheorghe A, Diaz LE, Perez de Heredia F, De Miguel P, Gonzalez E, Aguilera CM, Rangel OD, Gil-Campos M, Flores K, Maldonado J, Hoyos R, Gil A, Moreno L, Marcos A. 2013. Immunological biomarkers in childhood and adolescence obesity PROCEEDINGS OF THE NUTRITION SOCIETY, 72 :E91-E91 DOI Author Url

Baccan GC, Diaz LE, Hernandez O, Gheorghe A, Perez de Heredia F, Mujico J, De La Fuente M, Marcos A. 2013. Obesity induction during adolescence in ICR-CD1 mice causes CVD risk in the adulthood PROCEEDINGS OF THE NUTRITION SOCIETY, 72 :E13-E13 DOI Author Url

Gheorghe A, Diaz LE, Perez De Heredia Benedicte F, Gomez-Martinez S, Zapatera B, Veiga OL, Garagorri J, Marti A, Campoy C, Morande G, Marcos A. 2011. Changes in homocysteine, lipids and apolipoprotein levels in overweight and obese Spanish adolescents. Preliminary results of the EVASYON Study Obesity Reviews, 18th European Congress on Obesity 12 :118-119

Gheorghe A, Andres P, Perez de Heredia F, Gomez-Martinez S, Veses A, Nova E, Morande G, Graell M, Marcos A. 2011. Changes in peripheral white cell profile and lymphocyte subsets in early onset of anorexia nervosa. The ANABEL Study PROCEEDINGS OF THE NUTRITION SOCIETY, 70 :E34-E34 DOI Author Url

Wood IS, Perez De Heredia Benedicte F, Stezhka T, Trayhurn P. 2010. Hypoxia increases lactate release and monocarboxylate transporter (MCT1, MCT4) expression in human adipocytes Obesity Reviews, XI International Congress on Obesity 11 :118-118

Perez De Heredia Benedicte F, Wood IS, Trayhurn P. 2010. Lactate enhances the inflammatory response in human preadipocytes in vitro Obesity Reviews, XI International Congress on Obesity 11 :122-122

Trayhurn P, de Heredia FP, Wang B, Wood IS. 2010. The Role of Hypoxia in Adipocyte Function and Dysfunction Clement K, Spiegelman BM, Christen Y. NOVEL INSIGHTS INTO ADIPOSE CELL FUNCTIONS, 9th Symposium on Endocrine Research and Medicine Interactions :45-60 DOI Author Url

Perez De Heredia Benedicte F, Wood IS, Trayhurn P. 2009. Acute and chronic hypoxia selectively modulates the expression of glucose transporters (GLUTs) in human adipocytes Obesity Facts, 17th European Congress on Obesity 2 :39-39

Perez De Heredia Benedicte F, Wood IS, Trayhurn P. 2009. Hypoxia modulates monocarboxylate transporter (MCT) expression in human adipocytes Proceedings of the Nutrition Society, The Nutrition Society Scottish Section Meeting 'Frontiers in Adipose Tissue Biology' 68 :E91-E91

Perez De Heredia Benedicte F, Larqué E, Portillo MP, Canteras M, Zamora S, Garaulet M. 2008. Cambios con la edad en la composición en ácidos grasos del tejido adiposo y el suero en ratas, y su relación con la adiposidad y la función insulínica Nutricion Hospitalaria, X Meeting of the Spanish Nutrition Society (SEN) 1 :104-104

Gomez S, Linde J, Nova E, Díaz LE, Wärnberg J, Romeo J, Mesana MI, Mesa JL, de Rufino Rivas P, Perez De Heredia Benedicte F, Marcos A, AVENA Group . 2006. Consumo de lácteos por los adolescentes españoles. Estudio AVENA Nutricion Hospitalaria, XI Meeting of the Spanish Nutrition Society (SEN) 21 :411-411

Perez De Heredia Benedicte F, Macarulla MT, Portillo MP, Zamora S, Garaulet M. 2006. Efecto de la dehidroepiandrosterona en la lipolisis del tejido adiposo visceral y subcutáneo de ratas Nutricion Hospitalaria, XI Meeting of the Spanish Nutrition Society (SEN) 21 :420-420

Perez De Heredia Benedicte F, Hernández-Morante JJ, Garaulet M, Zamora S. 2006. Relación entre DHEA y distribución del tejido adiposo. Un estudio multienfoque Nutricion Hospitalaria, XI Meeting of the Spanish Nutrition Society (SEN) 21 :404-404

Mendez M, Moreno LA, Mesana MI, Ortega F, Perez De Heredia Benedicte F, de Rufino P, Wärnberg J, Marcos A, Bueno M. 2004. Adjusting for timing of menarche affects estimates of overweight prevalence in Spanish adolescent girls. The AVENA Study International Journal of Obesity, 13th European Congress on Obesity 28 :S64-S64

Tomás C, Moreno LA, Mesana MI, Ortega F, Perez De Heredia Benedicte F, de Rufino P, Marcos A, Bueno M. 2004. Environmental determinants of overweight and obesity in Spanish adolescents. The AVENA Study International Journal of Obesity, 13th European Congress on Obesity 28 :S66-S66

Wärnberg J, Medina S, Moreno LA, Mesana MI, González-Gross M, Ruiz J, González-Lamuño D, Perez De Heredia Benedicte F, Marcos A, AVENA Group . 2004. Overweight and obesity in adolescents is associated with inflammation. The AVENA Study International Journal of Obesity, 13th European Congress on Obesity 28 :S74-S74 Author Url

Zamora S, Perez-Llamas F, Garaulet M, Perez De Heredia Benedicte F, AVENA Group . 2003. Dietary intake and habits in Spanish adolescents. Comparison with the Mediterranean diet Nutrition, IX Meeting of the Spanish Society of Nutrition (SEN) 19 :1032-1032

Martinez-Maluendas L, Perez De Heredia Benedicte F, Barea N, Gonzalez-Gross M, Romeo J, Torralba C, Mesana I, Ortega F, de Rufino-Rivas P, Marcos A, AVENA Group . 2003. Energy and selected nutrient intake in adolescents from Madrid. The AVENA Study Nutrition, IX Meeting of the Spanish Society of Nutrition (SEN) 19 :1047-1047

Warnberg J, Medina S, Gonzalez-Gross M, Diaz LE, Moreno LA, Ruiz J, Gonzalez-Lamuno D, Perez De Heredia Benedicte F, Marcos A, AVENA Group . 2003. Inflammatory protein concentration distribution in adolescents. The AVENA Study Nutrition, IX Meeting of the Spanish Society of Nutrition (SEN) 19 :1047-1047

Martinez-Maluendas L, Perez De Heredia Benedicte F, Gonzalez-Gross M, Barea N, Warnberg J, Medina S, Torralba C, Mesana MI, Ortega F, de Rufino-Rivas P, Marcos A, AVENA Group . 2003. Estimated energy and macronutrient intake in Spanish adolescents. AVENA STUDY ANNALS OF NUTRITION AND METABOLISM, 9th European Nutrition Conference 47 :504-504

Perez De Heredia Benedicte F, Zamora S, Perez-Llamas F, Garaulet M, AVENA Group . 2003. Food habits of the Spanish adolescents in the 21st century. Is the Mediterranean Diet disappearing? ANNALS OF NUTRITION AND METABOLISM, 9th European Nutrition Conference 47 :351-351

Joyanes M, Gomez S, Nova E, de la Rosa B, Gonzalez-Gross M, Asensio A, Perez De Heredia Benedicte F, Mesana MI, Marcos A. 2001. The relationship between vitamin E intake and CD4/CD8 ratio in seventeen-year-old Spanish adolescents. Avena Pilot Study Nutrition, VIII Meeting of the Spanish Society of Nutrition (SEN) 17 :1017-1017

Garaulet M, Perez De Heredia Benedicte F, Perez-Llamas F, Canteras M, Serrano M, Tebar FJ, Zamora S. Endocrine, metabolic and nutritional factors in the establishment of obesity and their relative significance Proceedings of the Nutrition Society, 59 :135A-135A Author Url

Journal article

Gheorghe A, Pérez de Heredia F, Hunsche C, Redondo N, Díaz LE, Hernández O, Marcos A, De la Fuente M. 2017. Oxidative stress and immunosenescence in spleen of obese mice can be reversed by 2-hydroxyoleic acid. Exp Physiol, DOI Author Url Public Url

Perez-de-Heredia F, Gomez-Martinez S, Diaz L-E, Veses AM, Nova E, Warnberg J, Huybrechts I, Vyncke K, Androutsos O, Ferrari M, Palacios G, Wastlund A, Kovacs E, Gottrand F, Gonzalez-Gross M, Castillo MJ, Sjostrom M, Manios Y, Kafatos A, Molnar D, Widhalm K, Moreno LA, Marcos A. 2015. Influence of sex, age, pubertal maturation and body mass index on circulating white blood cell counts in healthy European adolescents-the HELENA study EUROPEAN JOURNAL OF PEDIATRICS, 174 :999-1014 DOI Author Url Public Url

Martinez-Gomez D, Veses AM, Gomez-Martinez S, Perez de Heredia F, Castillo R, Santaliestra-Pasias AM, Elisa Calle M, Garcia-Fuentes M, Luis Veiga O, Marcos A. 2015. Television viewing time and risk of eating disorders in Spanish adolescents: AVENA and AFINOS studies PEDIATRICS INTERNATIONAL, 57 :455-460 DOI Author Url

Veses A, Gomez-Martinez S, Perez De Heredia Benedicte F, Esteban I, Castillo R, Estecha S, García-Fuentes M, Veiga OL, Calle ME, Marcos A. 2015. Cognition and the risk of eating disorders in Spanish adolescents: the AVENA & AFINOS Studies European Journal of Pediatrics, 174 :229-236 DOI Author Url Publisher Url

Pujol-Gimenez J, Perez de Heredia F, Idoate MA, Airley R, Lostao MP, Evans AR. 2015. Could GLUT12 be a potential therapeutic target in cancer? A preliminary report Journal of Cancer, 6 :139-143 DOI Author Url Public Url

Gómez-Martnez S, Martnez-Gómez D, Perez De Heredia F, Romeo J, Cuenca-Garcia M, Martn-Matillas M, Castillo M, Rey-López JP, Vicente-Rodriguez G, Moreno L, Marcos A. 2012. Eating habits and total and abdominal fat in Spanish adolescents: Influence of physical activity. the AVENA study Journal of Adolescent Health, 50 :403-409 DOI Author Url

Vyncke KE, Libuda L, De Vriendt T, Moreno LA, Van Winckel M, Manios Y, Gottrand F, Molnar D, Vanaelst B, Sjöström M, González-Gross M, Censi L, Widhalm K, Michels N, Gilbert CC, Xatzis C, Cuenca García M, Perez De Heredia Benedicte F, De Henauw S, Huybrechts I, The HELENA consortium . 2012. Dietary fatty acid intake, its food sources and determinants in healthy European adolescents. The HELENA study The British Journal of Nutrition: an international journal of nutritional science, DOI Author Url

Sanchez J, Perez-Heredia F, Priego T, Portillo MP, Zamora S, Garaulet M, Palou A. 2008. Dehydroepiandrosterone prevents age-associated alterations, increasing insulin sensitivity JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 19 :809-818 DOI Author Url

Ruiz JR, Ortega FB, Castillo MJ, Cano MD, Sola R, Mesa JL, Delgado M, Tercedor P, Chillón P, Martín M, Carreño F, Rodríguez GV, Castillo R, Arellano F, Sjöström M, Labayen I, Moreno LA, Bueno M, Sarriá A, Fleta J, Rodríguez G, Gil CM, Msana MI, Casajús JA, Blay VV, Blay MG, González-Lamuño D, Fuentes MG, Redondo-Figuero C, García Fuentes M, de Rufíno P, Pérez-Prieto R, Fernández D, Amigo T, Martí A, Martínez JA, Nova E, Zamora S, Garaulet M, Pérez-Llamas F, Baraza JC, Marín JF, Pérez de Heredia F, Fernández MA, González C, García R, Torralba C, Donat E, Morales E, García MD, Hernández JJ, Asensio A, Plaza FJ, López MJ, Marcos A, González-Gross M, Wärnberg J, Medina S, Sánchez Muniz F, Montero E, de la Rosa B, Gómez S, Samartín S, Romeo J, Álvarez R, Álvarez A, Barrios L, Leyva A, Payá B, Martínez L, Ramos E, Ortiz R, Urzanqui A. 2008. Birth weight and blood lipid levels in Spanish adolescents: Influence of selected APOE, APOC3 and PPARgamma2 gene polymorphisms. The AVENA Study BMC Medical Genetics, 9 DOI Author Url

Labayen I, Moreno LA, Ruiz JR, González-Gross M, Wärnberg J, Breidenassel C, Ortega FB, Marcos A, Bueno M, Marcos A, Castillo MJ, Zamora S, García Fuentes M, Bueno M, Cano MD, Sola R, Gutiérrez A, Mesa JL, Ruiz J, Delgado M, Tercedor P, Chillón P, Martín M, Carreño F, Ortega F, Rodríguez GV, Castillo R, Arellano F, González-Gross M, Wärnberg J, Medina S, Sánchez Muniz F, Nova E, Montero A, De La Rosa B, Gómez S, Samartín S, Romeo J, Álvarez R, Álvarez A, Barrios L, Leyva A, Payá B, Martínez L, Ramos E, Ortiz R, Urzanqui A, Garaulet M, Pérez-Llamas F, Baraza JC, Marín JF, Pérez De Heredia F, Fernández MA, González C, García R, Torralba C, Donat E, Morales E, García MD, Martínez JA, Hernández JJ, Asensio A, Plaza FJ, López MJ, González-Lamuño D, De Rufino P, Pérez-Prieto R, Fernández D, Amigo T, Moreno LA, Sarriá A, Fleta J, Rodríguez G, Gil CM, Mesana MI, Casajús JA, Blay V, Blay MG. 2008. Small birth weight and later body composition and fat distribution in adolescents: The AVENA study Obesity, 16 :1680-1686 DOI Author Url

Moreno LA, Mesana MI, González-Gross M, Gil CM, Ortega FB, Fleta J, Wärnberg J, León JF, Marcos A, Bueno M, Castillo MJ, Cano MD, Sola R, Gutiérrez A, Mesa JL, Ruiz J, Delgado M, Tercedor P, Chillón P, Martín M, Carreño F, Ortega F, Rodríguez GV, Castillo R, Arellano F, Medina S, Sánchez Muniz F, Nova E, Montero A, De La Rosa B, Gómez S, Samartín S, Romeo J, Álvarez R, Álvarez A, Barrios L, Leyva A, Payá B, Martínez L, Ramos E, Ortiz R, Urzanqui A, Zamora S, Garaulet M, Pérez-Llamas F, Baraza JC, Marín JF, Pérez De Heredia F, Fernández MA, González C, García R, Torralba C, Donat E, Morales E, García MD, Martínez JA, Hernández JJ, Asensio A, Plaza FJ, López MJ, García Fuentes M, González-Lamuño D, De Rufino P, Pérez-Prieto R, Fernández D, Amigo T, Sarriá A, Rodríguez G, Casajús JA, Blay V, Blay MG. 2007. Body fat distribution reference standards in Spanish adolescents: The AVENA Study International Journal of Obesity, 31 :1798-1805 DOI Author Url

Labayen I, Moreno LA, Marti A, González-Lamuño D, Wárnberg J, Ortega FB, Bueno G, Nova E, Ruiz JR, Garagorri JM, Martínez JA, García-Fuentes M, Bueno M, Marcos A, Castillo MJ, Marcos A, Zamora S, García Fuentes M, Castillo MJ, Cano MD, Sola R, Gutiérrez A, Mesa JL, Ruiz J, Delgado M, Tercedor P, Chillón P, Martín M, Carreño F, Ortega F, Rodríguez GV, Castillo R, Arellano F, Marcos A, González-Gross M, Wärnberg J, Medina S, Sánchez Muniz F, Montero A, De La Rosa B, Gómez S, Samartín S, Romeo J, Álvarez R, Álvarez A, Barrios L, Leyva A, Payá B, Martínez L, Ramos E, Ortiz R, Urzanqui A, Zamora S, Garaulet M, Pérez-Llamas F, Baraza JC, Marín JF, Pérez De Heredia F, Fernández MA, González C, García R, Torralba C, Donat E, Morales E, García MD, Hernández JJ, Asensio A, Plaza FJ, López MJ, García Fuentes M, De Rufino P, Pérez-Prieto R, Fernández D, Amigo T, Sarriá A, Fleta J, Rodríguez G, Gil CM, Mesana MI, Casajús JA, Blay V, Blay MG. 2007. Effect of the Ala12 allele in the PPARγ-2 gene on the relationship between birth weight and body composition in adolescents: The AVENA study Pediatric Research, 62 :615-619 DOI Author Url

Ruiz JR, Ortega FB, Tresaco B, Wärnberg J, Mesa JL, González-Gross M, Moreno LA, Marcos A, Gutiérrez A, Castillo MJ, Zamora S, García Fuentes M, Bueno M, Cano MD, Sola R, Delgado M, Tercedor P, Chillón P, Martín M, Carreño F, Rodríguez GV, Castillo R, Arellano F, Medina S, Sánchez Muniz F, Nova E, Montero A, De La Rosa B, Gómez S, Samartín S, Romeo J, Álvarez R, Álvarez A, Barrios L, Leyva A, Payá B, Martínez L, Ramos E, Ortiz R, Urzanqui A, Garaulet M, Pérez-Llamas F, Baraza JC, Marín JF, Pérez De Heredia F, Fernández MA, González C, García R, Torralba C, Donat E, Morales E, García MD, Martínez JA, Hernández JJ, Asensio A, Plaza FJ, López MJ, González-Lamuno D, De Rufino P, Pérez-Prieto R, Fernández D, Amigo T, Sarriá A, Fleta J, Rodríguez G, Gil CM, Mesana MI, Casajús JA, Blay V, Blay MG. 2006. Serum lipids, body mass index and waist circumference during pubertal development in Spanish adolescents: The AVENA study Hormone and Metabolic Research, 38 :832-837 DOI Author Url

Wärnberg J, Nova E, Moreno LA, Romeo J, Mesana MI, Ruiz JR, Ortega FB, Sjöström M, Bueno M, Marcos A, Castillo MJ, Zamora S, García Fuentes M, Cano MD, Sola R, Gutiérrez A, Mesa JL, Delgado M, Tercedor P, Chillón P, Martín M, Carreño F, Rodríguez GV, Castillo R, Arellano F, González-Gross M, Gómez S, Álvarez A, Barrios L, Leyva A, Payá B, Vallejo MC, Sánchez Muniz F, Martínez L, Ramos E, Ortiz De Zárate R, Urzanqui A, Garaulet M, Pérez-Llamas F, Baraza JC, Marín JF, Pérez De Heredia F, Fernández MA, González C, García R, Torralba C, Donat E, Morales E, García MD, Martínez JA, Hernández JJ, Asensio A, Plaza FJ, López MJ, González-Lamuño D, De Rufino P, Pérez-Prieto R, Fernández D, Amigo T, Sarriá A, Fleta J, Rodríguez G, Gil CM, Casajús JA, Blay V, Blay MG. 2006. Inflammatory proteins are related to total and abdominal adiposity in a healthy adolescent population: The AVENA Study American Journal of Clinical Nutrition, 84 :505-512 DOI Author Url

Ruiz JR, Ortega FB, Moreno LA, Wärnberg J, Gonzalez-Gross M, Cano MD, Gutierrez A, Castillo MJ, Sola R, Luyckx F, Mesa JL, Delgado M, Tercedor P, Chillón P, Martín M, Carreño F, Rodríguez GV, Castillo R, Arellano F, Marcos A, Medina S, Sánchez Muniz F, Nova E, Montero A, de la Rosa B, Gómez S, Samart́in S, Romeo J, Álvarez R, Álvarez A, Barrios L, Leyva A, Payá B, Martínez L, Ramos E, Ortiz R, Urzanqui A, Zamora S, Garaulet M, Pérez-Llamas F, Baraza JC, Marín JF, Pérez de Heredia F, Fernández MA, González C, García R, Torralba C, Donat E, Morales E, García MD, Martínez JA, Hernández JJ, Asensio A, Plaza FJ, López MJ, García Fuentes M, González-Lamuño D, de Rufino P, Pérez-Prieto R, Fernández D, Amigo T, Bueno M, Sarriá A, Fleta J, Rodríguez G, Gil CM, Mesana MI, Casajús JA, Blay V, Blay MG. 2006. Reference values for serum lipids and lipoproteins in Spanish adolescents: The AVENA study Sozial- und Praventivmedizin, 51 :99-109 DOI Author Url

Moreno LA, Mesana MI, González-Gross M, Gil CM, Fleta J, Wärnberg J, Ruiz JR, Sarría A, Marcos A, Bueno M, Castillo MJ, Cano MD, Sola R, Gutiérrez A, Mesa JL, Delgado M, Tercedor P, Chillón P, Martín M, Carreño F, Ortega F, Rodríguez GV, Castillo R, Arellano F, Medina S, Sánchez Muniz F, Nova E, Montero A, de la Rosa B, Gómez S, Samartín S, Romeo J, Álvarez R, Álvarez A, Barrios L, Leyva L, Payá B, Martínez L, Ramos E, Ortiz R, Urzanqui A, Zamora S, Garaulet M, Pérez-Llamas F, Baraza JC, Marín JF, Pérez de Heredia F, Fernández MA, González C, García R, Torralba C, Donat E, Morales E, García MD, Martínez JA, Hernández JJ, Asensio A, Plaza FJ, López MJ, García Fuentes M, González-Lamuño D, de Rufino P, Pérez-Prieto R, Fernández D, Amigo T, Rodríguez G, Casajús JA, Blay V, Blay MG. 2006. Anthropometric body fat composition reference values in Spanish adolescents. The AVENA Study European Journal of Clinical Nutrition, 60 :191-196 DOI Author Url

Ortega FB, Ruiz JR, Castillo MJ, Moreno LA, González-Gross M, Wärnberg J, Gutiérrez A, García Fuentes M, Bueno M, Cano MD, Sola R, Mesa JL, Delgado M, Tercedor P, Chillón P, Martín M, Carreño F, Rodríguez GV, Castillo R, Arellano F, Medina S, Sánchez Muniz F, Nova E, Montero A, de la Rosa B, Gómez S, Samartín S, Romeo J, Álvarez R, Barrios L, Leyva A, Payá B, Martínez L, Ramos E, Ortiz R, Urzanqui A, Zamora S, Garaulet M, Pérez-Llamas F, Baraza JC, Marín JF, Pérez de Heredia F, Fernández MA, González C, García R, Torralba C, Donat E, Morales E, García MD, Martínez JA, Hernández JJ, Asensio A, Plaza FJ, López MJ, González-Lamuño D, de Rufino P, Pérez-Prieto R, Fernández D, Amigo T, Sarriá A, Fleta J, Rodríguez G, Gil CM, Mesana MI, Casajús JA, Blay V, Blay MG. 2005. Low level of physical fitness in Spanish adolescents. Relevance for future cardiovascular health (AVENA study) Revista Espanola de Cardiologia, 58 :898-909 DOI Author Url

de Heredia FP, Gómez-Martínez S, Marcos A. Obesity, inflammation and the immune system. Proc Nutr Soc, 71 :332-338 DOI Author Url

González-Muniesa P, de Oliveira C, Pérez de Heredia F, Thompson MP, Trayhurn P. Fatty acids and hypoxia stimulate the expression and secretion of the adipokine ANGPTL4 (angiopoietin-like protein 4/ fasting-induced adipose factor) by human adipocytes. J Nutrigenet Nutrigenomics, 4 :146-153 DOI Author Url

Garaulet M, Pérez de Heredia F. Behavioural therapy in the treatment of obesity (II): role of the Mediterranean diet. Nutr Hosp, 25 :9-17 DOI Author Url

Pérez de Heredia F, Wood IS, Trayhurn P. Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes. Pflugers Arch, 459 :509-518 DOI Author Url

Garaulet M, Pérez de Heredia F. Behavioural therapy in the treatment of obesity (I): new directions for clinical practice. Nutr Hosp, 24 :629-639 DOI Author Url

Pérez de Heredia F, Sánchez J, Priego T, Larqué E, Portillo MDP, Palou A, Zamora S, Garaulet M. Adiponectin is associated with serum and adipose tissue fatty acid composition in rats. J Endocrinol Invest, 32 :659-665 DOI Author Url

Wood IS, de Heredia FP, Wang B, Trayhurn P. Cellular hypoxia and adipose tissue dysfunction in obesity. Proc Nutr Soc, 68 :370-377 DOI Author Url

de Heredia FP, Larqué E, Zamora S, Garaulet M. Dehydroepiandrosterone modifies rat fatty acid composition of serum and different adipose tissue depots and lowers serum insulin levels. J Endocrinol, 201 :67-74 DOI Author Url

Pérez-de-Heredia F, Sánchez J, Priego T, Nicolás F, Portillo MDP, Palou A, Zamora S, Garaulet M. Adiponectin is involved in the protective effect of DHEA against metabolic risk in aged rats. Steroids, 73 :1128-1136 DOI Author Url

Hernández-Morante JJ, Pérez-de-Heredia F, Luján JA, Zamora S, Garaulet M. Role of DHEA-S on body fat distribution: gender- and depot-specific stimulation of adipose tissue lipolysis. Steroids, 73 :209-215 DOI Author Url

de Heredia FP, Larque E, Portillo MDP, Canteras M, Zamora S, Garaulet M. Age-related changes in fatty acids from different adipose depots in rat and their association with adiposity and insulin. Nutrition, 24 :1013-1022 DOI Author Url

Garaulet M, Hernández-Morante JJ, de Heredia FP, Tébar FJ. Adiponectin, the controversial hormone. Public Health Nutr, 10 :1145-1150 DOI Author Url

de Heredia FP, Cerezo D, Zamora S, Garaulet M. Effect of dehydroepiandrosterone on protein and fat digestibility, body protein and muscular composition in high-fat-diet-fed old rats. Br J Nutr, 97 :464-470 DOI Author Url

Pérez de Heredia F, Garaulet M, Portillo MP, Zamora S. Resistance to dietary obesity in rats given different high-energy diets. Int J Vitam Nutr Res, 76 :271-279 DOI Author Url

Pérez-Llamas F, Garaulet M, Herrero F, Palma JT, Pérez de Heredia F, Marín R, Zamora S. [Multivalent informatics application for studies of the nutritional status of the population. Assessment of food intake]. Nutr Hosp, 19 :160-166 Author Url

Iglesia I, Mouratidou T, González-Gross M, Novakovik R, Breidenassel C, Jiménez-Pavón D, Huybrechts I, DeHenauw S, Geelen A, Gottrand F, Kafatos A, Mistura L, Perez De Heredia Benedicte F, Widhalm K, Manios Y, Molnar D, Stehle P, Gurinovic M, Cavelaars AEJM, Van’t Veer P, Moreno LA, HELENA consortium . Socioeconomic factors are associated with folate and vitamin B12 intakes and related biomarkers concentrations in European adolescents: The Healthy Lifestyle in Europe by Nutrition in Adolescence Study Nutrition Research, DOI Author Url

Perez De Heredia Benedicte F, Garaulet M, Gómez-Martínez S, Díaz LE, Wärnberg J, Androutsos O, Michels N, Breidenassel C, Cuenca-García M, Huybrechts I, Gottrand F, Ferrari M, Santaliestra-Pasías AM, Kafatos A, Molnár D, Sjöstrom M, Widhalm K, Moreno LA, Marcos A, HELENA Study Group . Self-reported sleep duration, white blood cell counts and cytokine profiles in European adolescents. The HELENA Study Sleep Medicine, DOI Author Url

Magrone T, Perez De Heredia Benedicte F, Jirillo E, Morabito G, Marcos A, Serafini M. Functional foods and nutraceuticals as therapeutic tools for the treatment of diet-related diseases Can. J. Physiol. Pharmacol, 91 :387-396 DOI Author Url

Trayhurn P, Perez De Heredia Benedicte F, Wang B, de Oliveira C, González-Muniesa P, Wood IS. Cellular hypoxia: a key modulator of adipocyte function in obesity? Adipobiology, 1 :19-26 DOI

Nova E, Perez De Heredia Benedicte F, Gómez-Martínez S, Marcos A. The role of probiotics on the microbiota: effect on obesity NUTRITION IN CLINICAL PRACTICE, 31 :387-400 DOI Author Url

Perez De Heredia Benedicte F, Redondo N, Gheorghe A, Diaz LE, Baccan GC, de la Fuente M, Marcos A. 2-OHOA supplementation reduced adiposity and improved cardiometabolic risk to a greater extent than n-3 PUFA in obese mice Obesity Research and Clinical Practice, Public Url

Chapters

de Heredia F, Díaz L, Hernández A, Veses A, Gómez-Martínez S, Marcos A. 2015. The Role of Antioxidants in Children’s Growth and Development Antioxidants in Health and Disease :53-70 CRC Press 9781466580039 DOI

Trayhurn P, Perez De Heredia Benedicte F, Wang B, Wood IS. 2010. Novel Insights into Adipose Cell Functions Clément K, Spiegelman BM. Novel Insights into Adipose Cell Functions :45-60 Springer 9783642135163 Publisher Url

Perez De Heredia Benedicte F, Díaz LE, Hernández A, Veses AM, Gómez-Martínez S, Marcos A. The role of antioxidants in children’s growth and development Zampelas A, Micha R. Antioxidants in Health and Disease: Myths or Scientific Evidence? :53-69 CRC Press, Taylor & Francis. Boca Raton, FL 978-1-4665-8011-4 DOI

Perez De Heredia Benedicte F, Martinez-Gomez D, Gomez-Martinez S, Marcos A. Effect of dietary patterns and physical activity in the establishment of abdominal obesity in adolescents Watson RR. Nutrition in the Prevention and Treatment of Abdominal Obesity :27-37 Elsevier 978-0-12-407934-2 DOI

Perez De Heredia Benedicte F, Garaulet M. The role of site-specific adipose tissue fatty acid composition in obesity Watson RR. Nutrition in the Prevention and Treatment of Abdominal Obesity :489-502 Elsevier 978-0-12-407934-2 DOI

Zapatera B, Veses AM, Perez De Heredia Benedicte F, Marcos A. Investigación en obesidad [Spanish] Morandé , Graell , Blanco . Trastornos de la conducta alimentaria y obesidad. Un enfoque integral [Spanish] :603-606 978-84-9835-741-7

Perez De Heredia Benedicte F, Romeo J, Gómez-Martínez S, Díaz LE, Pozo T, Marcos A. Food supplements and immune function in humans Watson R, Preedy V. Bioactive food as interventions for arthritis and related inflammatory diseases :145-156 Academic Press (Elsevier) 978-0-12-397156-2 DOI Publisher Url

Perez De Heredia Benedicte F, Hernández-Morante JJ, Garaulet M. Adipose tissue as a target for dehydroepiandrosterone and its sulphate Watson RR. DHEA in human health and aging :313-330 CRC Press, Taylor & Francis Group 978-1-4398-3883-9 Publisher Url

Perez De Heredia Benedicte F, Wood IS, Trayhurn P. El tejido adiposo y la inflamación asociada a la obesidad: papel de la hipoxia (Adipose tissue and obesity-associated inflammation: role of hypoxia) [In Spanish] Marcos A. Inmunonutrición: en la salud y la enfermedad (Immunonutrition: in health and disease) :510-518 Editorial Médica Panamericana. Madrid (Spain) 978-84-9835-402-7 Publisher Url

Warburton J, Perez De Heredia Benedicte F. The role of immune cells in adipose tissue Calder P, Kulkarni A. Nutrition, Immunity and Infection :43-56 Taylor & Francis 9781482253979 DOI

Mujico JR, Perez De Heredia Benedicte F, Gómez-Martínez S, Marcos A. Malnutrition and Inflammation Khatami M. Inflammation, Chronic Diseases and Cancer. Cell and Molecular Biology, Immunology and Clinical Bases :357-374 InTech 978-953-51-0102-4 DOI Publisher Url

Engagement & Impact

Conference organisation:

13th European Nutrition Conference., Co-chair of poster session. 2019

IUNS 21st International Congress of Nutrition, Organization committee, http://www.icn2017.com/. 2014

IUNS 20th International Congress of Nutrition, Abstract reviewer, http://icn2013.com/pages/welcome. 2013

22nd European Childhood Obesity Group (ECOG) Meeting, Session co-chair, http://www.ecog-obesity.eu/Meetings. 2012

6th International Immunonutrition Workshop, Session co-chair, http://www.immunonutritionworkshop.com/. 2012

11th European Nutrition Conference FENS, Session co-chair, http://www.fensmadrid2011.com/. 2011

VIII Scientific Meeting of the Spanish Society of Nutrition (SEN), Assistant, http://www.sennutricion.org/es/reuniones-congresos-sen. 2001

10th Anniversary of the International Symposium on Immunonutrition, Organization committee, http://www.immunonutrition-isin.org/symposium2017/.

Conference presentation:

A high-protein Mediterranean diet and resistance exercise for cardiac rehabilitation: a pilot randomised controlled trial., 13th European Nutrition Conference, Dublin, Poster presentation. 2019

A high protein Mediterranean diet and resistance training for the amelioration of cardiometabolic risk markers in cardiac rehabilitation patients with sarcopenic obesity, BACPR Exercise Professionals Spring Group Study Da, Birmingham, Poster presentation. 2019

A high-protein Mediterranean diet and resistance training on the amelioration of cardiometabolic risk markers in cardiac rehabilitation patients with sarcopenic obesity, 26th European Congress on Obesity, Glasgow, Scotland, Poster presentation. 2019

Comparison of three commonly used indicators of abdominal obesity in estimating prevalence and metabolic risk, 12th European Nutrition Conference, Berlin, Poster presentation. 2015

The effect of body mass on bone morphology interpretations, 5th European Society for the study of Human Evolution, London (UK), Poster presentation. 2015

Effect of mono- and poly-unsaturated fatty acid intake on cardiovascular risk factors in obese animals (In Spanish), II Meeting of the Spanish Federation of Nutrition Societies (FESNAD), Seville (Spain), Poster presentation. 2015

Intake of mono- and poly-unsaturated fatty acids improves function and redox status of spleen leukocytes in obese animals (In Spanish), III Meeting of the Spanish Federation of Nutrition Societies, Seville (Spain), Poster presentation. 2015

Diet and physical activity interact with the 514c/t polymorphism in hepatic lipase gene on serum lipid and fatty acid concentrations, 20th International Congress of Nutrition, Granada (Spain), Poster presentation. 2013

Differences on lymphocyte subset counts according to the degree of overweight-obesity in adolescents from Madrid. The AFINOS Study, 6th International Immunonutrition Workshop., Palma de Mallorca (Spain), Poster presentation. 2012

Immunological biomarkers in childhood and adolescence obesity, 6th International Immunonutrition Workshop., Palma de Mallorca (Spain), Poster presentation. 2012

Lymphocyte subsets, anthropometric measurements and body composition in European adolescents. The HELENA Study, 6th International Immunonutrition Workshop, Palma de Mallorca (Spain), Oral presentation. 2012

Sleep duration and lymphocyte subsets profile in European adolescents. The HELENA Study, 6th International Immunonutrition Workshop, Palma de Mallorca (Spain), Oral presentation. 2012

White blood cell count is associated with features of the metabolic syndrome in European adolescents. The HELENA Study, 6th International Immunonutrition Workshop, Palma de Mallorca (Spain), Oral presentation. 2012

Research Grants Awarded:

Liverpool Clinical Commissioning Group, Feasibility of a High-protein Mediterranean diet and resistance exercise randomised controlled trial in sarcopenic obese cardiac rehabilitation patients., Prof Dick HJ Thijssen (PI), LJMU; Dr Ian Davis, LJMU; Prof Gregory Lip, University of Liverpool; Dr Tom Butler, University of Chester; Dr Joseph Mills, Liverpool Heart and Chest Hospital, Grant value (£): £27,166, Duration of research project: 12 months. 2019

Spanish Ministry of Science - Programme for training university lecturers, Research into adipose tissue physiology and factors that promote obesity with ageing, Marta Garaulet; Salvador Zamora; University of Murcia (Spain), Grant value (£): 34,000, Duration of research project: 2001-2005. 2001

Foundation Alfonso Martin Escudero (Spain), Effects of hypoxia on nutrient uptake and utilization in human adipose tissue, Prof. Paul Trayhurn, Grant value (£): 38,900, Duration of research project: 2007-2009.

Spanish Ministry of Economy and Competitiveness, Biological, psychological, environmental and familiar markers for optimizing the diagnosis, prognosis and treatment of eating disorders and obesity in children. Case-control study (ANOBAS), Ana Rosa Sepúlveda, Grant value (£): 46,700, Duration of research project: 2012-2015.

Other invited event:

XI ISIN Conference on Immunonutrition, London (UK), Invited oral presentation. 2018

Congress of the Spanish Society of Nutrition, Pamplona, Spain, Invited talk. 2014

Symposium “Globesity and its Metabolic and Digestive Consequences”, Parma, Italy, Invited talk. 2014

Award:

Teaching Excellence Awards - Rising Star, Liverpool John Moores University. 2018

Second prize in the 10th Award of the Spanish Royal Academy of Veterinary Sciences, SSpanish Royal Academy of Veterinary Sciences. 2014

Best Oral Communication "Javier Romeo", 6th International Immunonutrition Workshop (Palma de Mallorca, Spain). 2012

Research Award for the project "DHEA as a therapeutic agent for obesity and its relationship with adipose tissue distribution. Potential metabolic routes”., Royal Academy of Pharmacy of Murcia. 2006

Membership of professional bodies:

Member, International Society of Immunonutrition (ISIN), http://www.immunonutrition-isin.org/. 2017

Member, Association for the Study of Obesity (UK), https://www.aso.org.uk/. 2016

Member, Society for Endocrinology. 2013

Member, The Nutrition Society. 2013

Member, Spanish Society for the Study of Obesity. 2009

Member, The Nutrition Society. 2009

External PGR examinations performed:

University of the Basque Country, PhD, Effects of two phenolic compounds, resveratrol and pterostilbene, on fat accumulation and related co-morbilities. 2014

University of Navarra, PhD, Functional characterization of the glucose transporter Glut12 and study of its expression in cancer and Alzheimer disease. 2013

University of Murcia, PhD, Menopausia y tejido adiposo. Tratamiento con sulfato-dehidroepiandrosterona sobre la obesidad. 2012

Other Professional Activity:

Grant reviewer for the BBSRC (2018).

Grant reviewer for the Hugh Greenwood Legacy Fund (2018).

Grant reviewer for the MRC (2018).

Grant reviewer for the Physiological Society (2018).

Reviewer for Annals of Nutrition and Metabolism (2016-2018).

Reviewer for Applied Physiology, Nutrition and Metabolism journal (2018).

Reviewer for BioMed Research International journal (2017).

Reviewer for European Journal of Pediatrics (2018).

Reviewer for PloS ONE jounral (2014).

Reviewer for SpringerPlus journal (2015).