Liverpool Skylilne

Pharmacy and Biomolecular Sciences

Prof Khalid Rahman

Prof Khalid Rahman

Telephone: 0151 231 2087

ORCID

Publications

Journal article

Chen Q, Rahman K, Wang S-J, Zhou S, Zhang H. 2019. Scutellaria barbata: A Review of Chemical Constituents, Pharmacological Activities and Clinical Application. Current pharmaceutical design, DOI Author Url

Chen W-H, Zhang Z-Z, Ban Y-F, Rahman K, Ye B-Z, Sun X-L, Tan H-Y, Zheng X-H, Liu H-Y, Xu L-C, Yan B, Han T. 2019. Cynanchum bungei Decne and its two related species for "Baishouwu": A review on traditional uses, phytochemistry, and pharmacological activities JOURNAL OF ETHNOPHARMACOLOGY, 243 DOI Author Url

Ming Q, Dong X, Wu S, Zhu B, Jia M, Zheng C, Rahman K, Han T, Qin L. 2019. UHPLC-HRMSn Analysis Reveals the Dynamic Metabonomic Responses of Salvia miltiorrhiza Hairy Roots to Polysaccharide Fraction from Trichoderma atroviride BIOMOLECULES, 9 DOI Author Url

Li X-Q, Zhu J-Y, Pan R-R, Shen Y-L, Rahman K, Zhang C-Y, Zhang L-J, Luan X, Zhang H. 2019. Therapeutic effect of Dongbai-Tonglin-Fang, a Chinese herbal formula, on urinary tract infection in rat model JOURNAL OF ETHNOPHARMACOLOGY, 241 DOI Author Url Public Url

Peng W, Ming Q-L, Zhai X, Zhang Q, Rahman K, Wu S-J, Qin L-P, Han T. 2019. Polysaccharide Fraction Extracted from Endophytic Fungus Trichoderma atroviride D16 Has an Influence on the Proteomics Profile of the Salvia miltiorrhiza Hairy Roots. Biomolecules, 9 DOI Author Url Publisher Url Public Url

Zhou Y-X, Zhang R-Q, Rahman K, Cao Z-X, Zhang H, Peng C. 2019. Diverse Pharmacological Activities and Potential Medicinal Benefits of Geniposide EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, DOI Author Url Public Url

Sun M-Y, Wang S-J, Li X-Q, Shen Y-L, Lu J-R, Tian X-H, Rahman K, Zhang L-J, Nian H, Zhang H. 2019. CXCL6 Promotes Renal Interstitial Fibrosis in Diabetic Nephropathy by Activating JAK/STAT3 Signaling Pathway Frontiers in Pharmacology, 10 DOI Author Url Publisher Url Public Url

Wang S-J, Wang X-H, Dai Y-Y, Ma M-H, Rahman K, Nian H, Zhang H. 2019. Prunella vulgaris: A comprehensive review of chemical constituents, pharmacological effects and clinical applications. Current Pharmaceutical Design, DOI Author Url Publisher Url Public Url

Sun Y, Yang H, Zhang Q, Qin L, Li P, Lee J, Chen S, Rahman K, Kang T, Jia M. 2019. Genetic diversity and its conservation implications of Vitex rotundifolia (Lamiaceae) populations in East Asia PeerJ, 2019 DOI Author Url Publisher Url Public Url

Shen Y-L, Wang S-J, Rahman K, Zhang L-J, Zhang H. 2018. Chinese Herbal Formulas and Renal Fibrosis: An Overview Current Pharmaceutical Design, 24 :2774-2781 DOI Author Url Publisher Url Public Url

Zhang C-Y, Pan R-R, Zhang X-D, Zhou Y, Ye Y, Xia J, Rahman K, Zhang H, Zhu J-Y. 2018. New tetracyclic triterpenoids from Jatropha gossypiifolia induce cell-cycle arrest and apoptosis in RKO cells FITOTERAPIA, 130 :145-151 DOI Author Url Public Url

Peng W, Shen H, Lin B, Han P, Li C, Zhang Q, Ye B, Rahman K, Xin H, Qin L, Han T. 2018. Docking study and antiosteoporosis effects of a dibenzylbutane lignan isolated from Litsea cubeba targeting Cathepsin K and MEK1 MEDICINAL CHEMISTRY RESEARCH, 27 :2062-2070 DOI Author Url

Zhang C-Y, Zhang L-J, Lu Z-C, Ma C-Y, Ye Y, Rahman K, Zhang H, Zhu J-Y. 2018. Antitumor Activity of Diterpenoids from Jatropha gossypiifolia: Cell Cycle Arrest and Apoptosis-Inducing Activity in RKO Colon Cancer Cells. Journal of Natural Products, DOI Author Url Publisher Url Public Url

Li X-Q, Song Y-N, Wang S-J, Rahman K, Zhu J-Y, Zhang H. 2018. Saikosaponins: a review of pharmacological effects JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 20 :399-411 DOI Author Url Public Url

Zhai X, Luo D, Li X, Han T, Jia M, Kong Z, Ji J, Rahman K, Qin L, Zheng C. 2018. Endophyte Chaetomium globosum D38 Promotes Bioactive Constituents Accumulation and Root Production in Salvia miltiorrhiza FRONTIERS IN MICROBIOLOGY, 8 DOI Author Url Public Url

Hismiogullari AA, Hismiogullari SE, Sel T, Kilic O, Rahman K. 2018. EFFECT OF TAURODEHYDROCHOLIC ACID ON THE HEPATIC EXPRESSION OF ABCG5 AND ABCG8 AND BILIARY PARAMETERS IN THE FISTULA RAT ACTA MEDICA MEDITERRANEA, 34 :33-38 DOI Author Url Publisher Url Public Url

Li X-Q, Rahman K, Zhu J-Y, Zhang H. 2018. Chemical Constituents and Pharmacological Activities of Stellera chamaejasme CURRENT PHARMACEUTICAL DESIGN, 24 :2825-2838 DOI Author Url Public Url

Zhang C-Y, Luo L, Xia J, Song Y-N, Zhang L-J, Zhang M, Rahman K, Ye Y, Zhang H, Zhu J-Y. 2017. Sesquiterpenes and lignans from the flower buds of Daphne genkwa and their nitric oxide inhibitory activities. Nat Prod Res, :1-7 DOI Author Url Public Url

Sun M-Y, Zhu J-Y, Zhang C-Y, Zhang M, Song Y-N, Rahman K, Zhang L-J, Zhang H. 2017. Autophagy regulated by lncRNA HOTAIR contributes to the cisplatin-induced resistance in endometrial cancer cells BIOTECHNOLOGY LETTERS, 39 :1477-1484 DOI Author Url Public Url

Zhang L-J, Zhu J-Y, Sun M-Y, Song Y-N, Rahman K, Peng C, Zhang M, Ye Y-M, Zhang H. 2017. Anti-inflammatory effect of Man-Pen-Fang, a Chinese herbal compound, on chronic pelvic inflammation in rats JOURNAL OF ETHNOPHARMACOLOGY, 208 :57-65 DOI Author Url Public Url

Zhu J-Y, Zhang C-Y, Dai J-J, Rahman K, Zhang H. 2017. Diterpenoids with thioredoxin reductase inhibitory activities from Jatropha multifida. Nat Prod Res, :1-6 DOI Author Url Public Url

Zhai X, Jia M, Chen L, Zheng C-J, Rahman K, Han T, Qin L-P. 2017. The regulatory mechanism of fungal elicitor-induced secondary metabolite biosynthesis in medical plants. Critical Reviews in Microbiology, 43 :238-261 DOI Author Url Public Url

Li Q, Qu F-L, Gao Y, Jiang Y-P, Rahman K, Lee K-H, Han T, Qin L-P. 2017. Piper sarmentosum Roxb. produces antidepressant-like effects in rodents, associated with activation of the CREB-BDNF-ERK signalling pathway and reversal of HPA axis hyperactivity. J Ethnopharmacol, DOI Author Url Public Url

Elosta A, Slevin M, Rahman K, Ahmed N. 2017. Aged garlic has more potent antiglycation and antioxidant properties compared to fresh garlic extract in vitro SCIENTIFIC REPORTS, 7 DOI Author Url Public Url

Jia M, Chen L, Xin H-L, Zheng C-J, Rahman K, Han T, Qin L-P. 2016. A Friendly Relationship between Endophytic Fungi and Medicinal Plants: A Systematic Review FRONTIERS IN MICROBIOLOGY, 7 DOI Author Url Public Url

Zhang ND, Han T, Huang BK, Rahman K, Jiang YP, Xu HT, Qin LP, Xin HL, Zhang QY. 2016. Traditional Chinese Medicine formulas for the treatment of osteoporosis: Implication for antiosteoporotic drug discovery. Journal of ethnopharmacology, DOI Author Url Public Url

Chen L, Zhang Q-Y, Jia M, Ming Q-L, Yue W, Rahman K, Qin L-P, Han T. 2016. Endophytic fungi with antitumor activities: Their occurrence and anticancer compounds CRITICAL REVIEWS IN MICROBIOLOGY, 42 :454-473 DOI Author Url

Li M, Zhang ND, Wang Y, Han T, Jiang YP, Rahman K, Qin LP, Xin HL, Zhang QY. 2016. Coordinate regulatory osteogenesis effects of icariin, timosaponin B II and ferulic acid from traditional Chinese medicine formulas on UMR-106 osteoblastic cells and osteoblasts in neonatal rat calvaria cultures. Journal of ethnopharmacology, DOI Author Url

Yue W, Ming Q-L, Lin B, Rahman K, Zheng C-J, Han T, Qin L-P. 2016. Medicinal plant cell suspension cultures: pharmaceutical applications and high-yielding strategies for the desired secondary metabolites CRITICAL REVIEWS IN BIOTECHNOLOGY, 36 :215-232 DOI Author Url

Rahman K, Lowe GM, Smith S. 2016. Aged Garlic Extract Inhibits Human Platelet Aggregation by Altering Intracellular Signaling and Platelet Shape Change Journal of Nutrition, 146 :410S-415S DOI Author Url Publisher Url

Shu Z, Li X, Rahman K, Qin L, Zheng C. 2016. Chemical fingerprint and quantitative analysis for the quality evaluation of Vitex negundo seeds by reversed-phase high-performance liquid chromatography coupled with hierarchical clustering analysis JOURNAL OF SEPARATION SCIENCE, 39 :279-286 DOI Author Url Public Url

Li Y, Ye Y, Wang S-J, Xia W, Rahman K, Yue W, Zhang H. 2016. ANALGESIC, ANTI-INFLAMMATORYAND ANTIPYRETIC ACTIVITIES OF THE AQUEOUS EXTRACT OF GERANIUM CAROLINIANUM L AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES, 13 :105-113 DOI Author Url Public Url

Wang S-J, Yue W, Rahman K, Xin H-L, Zhang Q-Y, Qin L-P, Zhang H. 2016. Mechanism of Treatment of Kidney Deficiency and Osteoporosis is Similar by Traditional Chinese Medicine Current Pharmaceutical Design, 22 :312-320 DOI Author Url Public Url

Sun M-Y, Ye Y, Xiao L, Rahman K, Xia W, Zhang H. 2016. DAIDZEIN: A REVIEW OF PHARMACOLOGICAL EFFECTS AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES, 13 :117-132 DOI Author Url Public Url

Mao W-A, Sun Y-Y, Mao J-Y, Wang L, Zhang J, Zhou J, Rahman K, Ye Y. 2016. Inhibitory Effects of Angelica Polysaccharide on Activation of Mast Cells EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, DOI Author Url Public Url

Ma X-Q, Han T, Zhang X, Wu J-Z, Rahman K, Qin L-P, Zheng C-J. 2015. Kaempferitrin prevents bone lost in ovariectomized rats PHYTOMEDICINE, 22 :1159-1162 DOI Author Url

Peng W, Qiu X-Q, Shu Z-H, Liu Q-C, Hu M-B, Han T, Rahman K, Qin L-P, Zheng C-J. 2015. Hepatoprotective activity of total iridoid glycosides isolated from Paederia scandens (lour.) Merr. var. tomentosa JOURNAL OF ETHNOPHARMACOLOGY, 174 :317-321 DOI Author Url

Ji Q, Zheng G-Y, Xia W, Chen J-Y, Meng X-Y, Zhang H, Rahman K, Xin H-L. 2015. Inhibition of invasion and metastasis of human liver cancer HCCLM3 cells by portulacerebroside A PHARMACEUTICAL BIOLOGY, 53 :773-780 DOI Author Url Public Url

Zheng C-J, Li H-Q, Ren S-C, Xu C-L, Rahman K, Qin L-P, Sun Y-H. 2015. Phytochemical and Pharmacological Profile of Vitex negundo PHYTOTHERAPY RESEARCH, 29 :633-647 DOI Author Url

Su C-Y, Ming Q-L, Rahman K, Han T, Qin L-P. 2015. Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology CHINESE JOURNAL OF NATURAL MEDICINES, 13 :163-182 DOI Author Url

Zhou Y-X, Xin H-L, Rahman K, Wang S-J, Peng C, Zhang H. 2015. Portulaca oleracea L.: A Review of Phytochemistry and Pharmacological Effects BIOMED RESEARCH INTERNATIONAL, DOI Author Url Public Url

Ye Q, Wang S-J, Chen J-Y, Rahman K, Xin H-L, Zhang H. 2015. Medicinal Plants for the Treatment of Hypertrophic Scars EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, DOI Author Url Public Url

Su CY, Ming QL, Rahman K, Han T, Qin LP. 2015. Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology Chinese Journal of Natural Medicines, 13 :163-182 DOI Author Url

Zhou Y-X, Xia W, Yue W, Peng C, Rahman K, Zhang H. 2015. Rhein: A Review of Pharmacological Activities EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, DOI Author Url Public Url

Li Y-M, Jia M, Li H-Q, Zhang N-D, Wen X, Rahman K, Zhang Q-Y, Qin L-P. 2015. Cnidium monnieri: A Review of Traditional Uses, Phytochemical and Ethnopharmacological Properties AMERICAN JOURNAL OF CHINESE MEDICINE, 43 :835-877 DOI Author Url

Lowe GM, Gana K, Rahman K. 2015. Dietary supplementation with green tea extract promotes enhanced human leukocyte activity Journal of Complementary and Integrative Medicine, 12 :277-282 DOI Author Url Public Url

Pündük Z, Oral O, Özkayın N, Rahman K. 2014. Single dose of intra-muscular platlet rich plasma reverses the increase in plasma iron levels in exercise induced muscle damage: A pilot study Orthopaedic Journal of Sports Medicine, 2 DOI

Lin B, Zhao Y, Han P, Yue W, Ma X-Q, Rahman K, Zheng C-J, Qin L-P, Han T. 2014. Anti-arthritic activity of Xanthium strumarium L. extract on complete Freund's adjuvant induced arthritis in rats JOURNAL OF ETHNOPHARMACOLOGY, 155 :248-255 DOI Author Url

Li Y, Wang S-J, Xia W, Rahman K, Zhang Y, Peng H, Zhang H, Qin L-P. 2014. Effects of Tatariside G Isolated from Fagopyrum tataricum Roots on Apoptosis in Human Cervical Cancer HeLa Cells MOLECULES, 19 :11145-11159 DOI Author Url

Xue L-M, Zhang Q-Y, Han P, Jiang Y-P, Yan R-D, Wang Y, Rahman K, Jia M, Han T, Qin L-P. 2014. Hepatotoxic constituents and toxicological mechanism of Xanthium strumarium L. fruits JOURNAL OF ETHNOPHARMACOLOGY, 152 :272-282 DOI Author Url

Ming Q, Su C, Zheng C, Jia M, Zhang Q, Zhang H, Rahman K, Han T, Qin L. 2013. Elicitors from the endophytic fungus Trichoderma atroviride promote Salvia miltiorrhiza hairy root growth and tanshinone biosynthesis JOURNAL OF EXPERIMENTAL BOTANY, 64 :5687-5694 DOI Author Url

Hismiogullari AA, Hismiogullari SE, Rahman K. 2013. Isolation and biochemical analysis of vesicles from taurohyodeoxycholic acid-infused isolated perfused rat livers WORLD JOURNAL OF GASTROENTEROLOGY, 19 :6228-6236 DOI Author Url

Zheng C-J, Xu L-L, Li Y-Y, Han T, Zhang Q-Y, Ming Q-L, Rahman K, Qin L-P. 2013. Cytotoxic metabolites from the cultures of endophytic fungi from Panax ginseng APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 97 :7617-7625 DOI Author Url

Nie Y, Dong X, He Y, Yuan T, Han T, Rahman K, Qin L, Zhang Q. 2013. Medicinal plants of genus Curculigo: Traditional uses and a phytochemical and ethnopharmacological review JOURNAL OF ETHNOPHARMACOLOGY, 147 :547-563 DOI Author Url

Lin B, Zhang H, Zhao X-X, Rahman K, Wang Y, Ma X-Q, Zheng C-J, Zhang Q-Y, Han T, Qin L-P. 2013. Inhibitory effects of the root extract of Litsea cubeba (lour.) pers. on adjuvant arthritis in rats JOURNAL OF ETHNOPHARMACOLOGY, 147 :327-334 DOI Author Url

Ma X-Q, Zheng C-J, Zhang Y, Hu C-L, Lin B, Fu X-Y, Han L-Y, Xu L-S, Rahman K, Qin L-P. 2013. Antiosteoporotic flavonoids from Podocarpium podocarpum PHYTOCHEMISTRY LETTERS, 6 :118-122 DOI Author Url

Zheng C-J, Zhu J-Y, Yu W, Ma X-Q, Rahman K, Qin L-P. 2013. Labdane-Type Diterpenoids from the Fruits of Vitex trifolia JOURNAL OF NATURAL PRODUCTS, 76 :287-291 DOI Author Url

Wu L, Han T, Li W, Jia M, Xue L, Rahman K, Qin L. 2013. Geographic and Tissue Influences on Endophytic Fungal Communities of Taxus chinensis var. mairei in China CURRENT MICROBIOLOGY, 66 :40-48 DOI Author Url

Wu L-S, Hu C-L, Han T, Zheng C-J, Ma X-Q, Rahman K, Qin L-P. 2013. Cytotoxic metabolites from Perenniporia tephropora, an endophytic fungus from Taxus chinensis var. mairei APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 97 :305-315 DOI Author Url

Allison GL, Lowe GM, Rahman K. 2012. Aged garlic extract inhibits platelet activation by increasing intracellular cAMP and reducing the interaction of GPIIb/IIIa receptor with fibrinogen LIFE SCIENCES, 91 :1275-1280 DOI Author Url

Zhang Y, Han T, Ming Q, Wu L, Rahman K, Qin L. 2012. Alkaloids Produced by Endophytic Fungi: A Review NATURAL PRODUCT COMMUNICATIONS, 7 :963-968 Author Url

Ming Q, Han T, Li W, Zhang Q, Zhang H, Zheng C, Huang F, Rahman K, Qin L. 2012. Tanshinone IIA and tanshinone I production by Trichoderma atroviride D16, an endophytic fungus in Salvia miltiorrhiza PHYTOMEDICINE, 19 :330-333 DOI Author Url

Hu Y, Li J, Liu P, Chen X, Guo D-H, Li Q-S, Rahman K. 2012. Protection of SH-SY5Y Neuronal Cells from Glutamate-Induced Apoptosis by 3,6 '-Disinapoyl Sucrose, a Bioactive Compound Isolated from Radix Polygala JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, DOI Author Url

Hismiogullari AA, Bozdayi M, Erkan O, Sel T, Rahman K. 2012. Isolation of biliary lipid carrying vesicles, analysis of their biochemical properties and hepatic ABCG5 mRNA expression in diosgenin-fed rats TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, 37 :167-174 DOI Author Url

Xue L, Jiao L, Wang Y, Nie Y, Han T, Jiang Y, Rahman K, Zhang Q, Qin L. 2012. Effects and Interaction of Icariin, Curculigoside, and Berberine in Er-Xian Decoction, a Traditional Chinese Medicinal Formula, on Osteoclastic Bone Resorption EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, DOI Author Url

Zhang H, Zhang Y, Jiang Y-P, Zhang L-K, Peng C, He K, Rahman K, Qin L-P. 2012. Curative Effects of Oleanolic Acid on Formed Hypertrophic Scars in the Rabbit Ear Model EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, DOI Author Url

Jia M, Nie Y, Cao D-P, Xue Y-Y, Wang J-S, Zhao L, Rahman K, Zhang Q-Y, Qin L-P. 2012. Potential Antiosteoporotic Agents from Plants: A Comprehensive Review EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, DOI Author Url

Chew PY, Riley L, Graham DL, Rahman K, Lowe GM. 2012. Does lycopene offer human LDL any protection against myeloperoxidase activity? Molecular and cellular biochemistry, 361 :181-187 DOI

Ma X, Zheng C, Hu C, Rahman K, Qin L. 2011. The genus Desmodium (Fabaceae)-traditional uses in Chinese medicine, phytochemistry and pharmacology JOURNAL OF ETHNOPHARMACOLOGY, 138 :314-332 DOI Author Url

Chew PY, Riley L, Graham DL, Rahman K, Lowe GM. 2011. Does lycopene offer human LDL any protection against myeloperoxidase activity? Molecular and Cellular Biochemistry, :1-7 DOI

Hu Y, Guo D-H, Liu P, Cao J-J, Wang Y-P, Yin J, Zhu Y, Rahman K. 2011. Bioactive components from the tea polyphenols influence on endogenous antioxidant defense system and modulate inflammatory cytokines after total-body irradiation in mice PHYTOMEDICINE, 18 :970-975 DOI Author Url

Jantan I, Jumuddin FA, Saputri FC, Rahman K. 2011. Inhibitory effects of the extracts of Garcinia species on human low-density lipoprotein peroxidation and platelet aggregation in relation to their total phenolic contents JOURNAL OF MEDICINAL PLANTS RESEARCH, 5 :2699-2709 Author Url

Huang L-Z, Wei L, Zhao H-F, Huang B-K, Rahman K, Qin L-P. 2011. The effect of Eleutheroside E on behavioral alterations in murine sleep deprivation stress model EUROPEAN JOURNAL OF PHARMACOLOGY, 658 :150-155 DOI Author Url

Hismiogullari AA, Hismiogullari SE, Yavuz O, Essiz D, Rahman K. 2011. Evaluation of biochemical findings in mice exposed to thiamphenicol treatment AFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGY, 5 :428-431 Author Url

Du J, He D, Sun L-N, Han T, Zhang H, Qin L-P, Rahman K. 2010. Semen Hoveniae extract protects against acute alcohol-induced liver injury in mice PHARMACEUTICAL BIOLOGY, 48 :953-958 DOI Author Url Public Url

Hu Y, Liu P, Guo D-H, Rahman K, Wang D-X, Xie T-T. 2010. Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms PHARMACEUTICAL BIOLOGY, 48 :794-800 DOI Author Url

Yao Y, Jia M, Wu J-G, Zhang H, Sun L-N, Chen W-S, Rahman K. 2010. Anxiolytic and sedative-hypnotic activities of polygalasaponins from Polygala tenuifolia in mice PHARMACEUTICAL BIOLOGY, 48 :801-807 DOI Author Url

Liu P, Hu Y, Guo D-H, Lu B-R, Rahman K, Mu L-H, Wang D-X. 2010. Antioxidant activity of oligosaccharide ester extracted from Polygala tenuifolia roots in senescence-accelerated mice PHARMACEUTICAL BIOLOGY, 48 :828-833 DOI Author Url

Zheng C-J, Huang B-K, Han T, Zhang Q-Y, Zhang H, Rahman K, Qin L-P. 2010. Antinociceptive activities of the liposoluble fraction from Vitex negundo seeds PHARMACEUTICAL BIOLOGY, 48 :651-658 DOI Author Url

Hu Y, Liao H-B, Dai-Hong G, Liu P, Wang Y-Y, Rahman K. 2010. Antidepressant-like effects of 3,6 '-disinapoyl sucrose on hippocampal neuronal plasticity and neurotrophic signal pathway in chronically mild stressed rats NEUROCHEMISTRY INTERNATIONAL, 56 :461-465 DOI Author Url

Wang Y, Han T, Zhu Y, Zheng C-J, Ming Q-L, Rahman K, Qin L-P. 2010. Antidepressant properties of bioactive fractions from the extract of Crocus sativus L. JOURNAL OF NATURAL MEDICINES, 64 :24-30 DOI Author Url

Hu Y, Liao H-B, Liu P, Guo D-H, Rahman K. 2009. A bioactive compound from Polygala tenuifolia regulates efficiency of chronic stress on hypothalamic-pituitary-adrenal axis PHARMAZIE, 64 :605-608 DOI Author Url

Zheng C-J, Huang B-K, Han T, Zhang Q-Y, Zhang H, Rahman K, Qin L-P. 2009. Nitric Oxide Scavenging Lignans from Vitex negundo Seeds JOURNAL OF NATURAL PRODUCTS, 72 :1627-1630 DOI Author Url

Wang Y, Han T, Zhang X-G, Zheng C-J, Rahman K, Qin L-P. 2009. LC Fingerprint and Hierarchical Cluster Analysis of Crocus sativus L. from Different Locations in China CHROMATOGRAPHIA, 70 :143-149 DOI Author Url

Huang B, Qin L, Liu Y, Zhang Q, Rahman K, Zheng H. 2009. Chemical composition and hypnotic activities of the essential oil from roots of Valeriana officinalis var. latifolia in China CHEMISTRY OF NATURAL COMPOUNDS, 45 :560-561 DOI Author Url

Xu L-L, Han T, Wu J-Z, Zhang Q-Y, Zhang H, Huang B-K, Rahman K, Qin L-P. 2009. Comparative research of chemical constituents, antifungal and antitumor properties of ether extracts of Panax ginseng and its endophytic fungus PHYTOMEDICINE, 16 :609-616 DOI Author Url

Han T, Zhang Q-Y, Zhang H, Wen J, Wang Y, Huang B-K, Rahman K, Zheng H-C, Qin L-P. 2009. Authentication and quantitative analysis on the chemical profile of Xanthium fruit (Cang-Er-Zi) by high-performance liquid chromatography-diode-array detection tandem mass spectrometry method ANALYTICA CHIMICA ACTA, 634 :272-278 DOI Author Url

Hu Y, Guo D-H, Liu P, Rahman K, Wang D-X, Wang B. 2009. Antioxidant effects of a Rhodobryum roseum extract and its active components in isoproterenol-induced myocardial injury in rats and cardiac myocytes against oxidative stress-triggered damage PHARMAZIE, 64 :53-57 DOI Author Url

Hu Y, Zhu Y, Zhang QY, Xin HL, Qin LP, Lu BR, Rahman K, Zheng HC. 2008. Erratum: Population genetic structure of the medicinal plant Vitex rotundifolia in China: Implications for its use and conservation (Journal Integrative Plant Biology (2008) vol. 50 (9) (1118-1129)) Journal of Integrative Plant Biology, 50 :1601 DOI

Hu Y, Zhu Y, Zhang Q-Y, Xin H-L, Qin L-P, Lu B-R, Rahman K, Zheng H-C. 2008. Population genetic structure of the medicinal plant Vitex rotundifolia in China: Implications for its use and conservation JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 50 :1118-1129 DOI Author Url

Guo L, Wu J-Z, Han T, Cao T, Rahman K, Qin L-P. 2008. Chemical composition, antifungal and antitumor properties of ether extracts of Scapania verrucosa Heeg. and its endophytic fungus Chaetomium fusiforme MOLECULES, 13 :2114-2125 DOI Author Url

Yu-Zhu , Ting-Han , Hou T-T, Hu Y, Zhang Q-Y, Rahman K, Qin L-P. 2008. Comparative study of composition of essential oil from stigmas and of extract from corms of Crocus sativus CHEMISTRY OF NATURAL COMPOUNDS, 44 :666-667 DOI Author Url

Zhang H, Han T, Zhang L, Yu C-H, Wan D-G, Rahman K, Qin L-P, Peng C. 2008. Effects of tenuifolin extracted from radix polygalae on learning and memory: A behavioral and biochemical study on aged and amnesic mice PHYTOMEDICINE, 15 :587-594 DOI Author Url

Hu Y, Liu P, Dai-Hong G, Rahman K, Wang D-X, Chen M-L, Xie T-T. 2008. Behavioral and biochemical effects of Kaixin-San, a traditional Chinese medicinal empirical formula DRUG DEVELOPMENT RESEARCH, 69 :267-271 DOI Author Url

Qin L, Han T, Zhang Q, Cao D, Nian H, Rahman K, Zheng H. 2008. Antiosteoporotic chemical constituents from Er-Xian Decoction, a traditional Chinese herbal formula JOURNAL OF ETHNOPHARMACOLOGY, 118 :271-279 DOI Author Url

Chu C, Huang Y, Chen Y-F, Wu J-H, Rahman K, Zheng H-C, Qin L-P. 2008. Anti-nociceptive activity of aqueous fraction from the MeOH extracts of Paederia scandens in mice JOURNAL OF ETHNOPHARMACOLOGY, 118 :177-180 DOI Author Url

Chen Y-F, Li N, Jiao Y-L, Wei P, Zhang Q-Y, Rahman K, Zheng H-C, Qin L-P. 2008. Antinociceptive activity of petroleum ether fraction from the MeOH extracts of Paederia scandens in mice PHYTOMEDICINE, 15 :427-436 DOI Author Url

Han T, Hu Y, Zhou S-Y, Li H-L, Zhang Q-Y, Zhang H, Huang B-K, Rahman K, Zheng H-C, Qin L-P. 2008. Correlation between the genetic diversity and variation of total phenolic acids contents in Fructus Xanthii from different populations in China BIOMEDICAL CHROMATOGRAPHY, 22 :478-486 DOI Author Url

Cao DP, Zheng YN, Qin LP, Han T, Zhang H, Rahman K, Zhang QY. 2008. Curculigo orchioides, a traditional Chinese medicinal plant, prevents bone loss in ovariectomized rats MATURITAS, 59 :373-380 DOI Author Url

Chen Y-F, Zhang H, Zhang Q-Y, Wu J-Z, Li N, Rahman K, Zheng H-C, Qin L-P. 2007. Antinociceptive activity of n-butanol fraction from MeOH extracts of Paederia scandens in mice PHARMAZIE, 62 :943-948 DOI Author Url

Han T, Li H-L, Zhang Q-Y, Han P, Zheng H-C, Rahman K, Qin L-P. 2007. Bioactivity-guided fractionation for anti-inflammatory and analgesic properties and constituents of Xanthium strumarium L. PHYTOMEDICINE, 14 :825-829 DOI Author Url

Hu Y, Zhang Q-Y, Hou T-T, Xin H-L, Zheng H-C, Rahman K, Qin L-P. 2007. Estrogen-like activities in Vitex species from China determined by a cell based proliferation assay PHARMAZIE, 62 :872-875 DOI Author Url

Hu Y, Xin H-L, Zhang Q-Y, Zheng H-C, Rahman K, Qin L-P. 2007. Anti-nociceptive and anti-hyperprolactinemin activities of Fructus Viticis and its effective fractions and chemical constituents PHYTOMEDICINE, 14 :668-674 DOI Author Url

Lin S, Zhang H, Han T, Wu JZ, Rahman K, Qin LP. 2007. In vivo effect of casticin on acute inflammation Journal of Chinese Integrative Medicine, 5 :573-576 DOI Author Url

Hu Y, Hou T-T, Zhang Q-Y, Xin H-L, Zheng H-C, Rahman K, Qin L-P. 2007. Evaluation of the estrogenic activity of the constituents in the fruits of Vitex rotundifolia L. for the potential treatment of premenstrual syndrome JOURNAL OF PHARMACY AND PHARMACOLOGY, 59 :1307-1312 DOI Author Url

Hu Y, Zhang Q, Xin H, Qin L-P, Lu B-R, Rahman K, Zheng H. 2007. Association between chemical and genetic variation of Vitex rotundifolia populations from different locations in China: its implication for quality control of medicinal plants BIOMEDICAL CHROMATOGRAPHY, 21 :967-975 DOI Author Url

Lowe G, Rahman K. 2007. Nutraceuticals and health Food Science and Technology, 21 :30-31

Hu Y, Hou T-T, Xin H-L, Zhang Q-Y, Zheng H-C, Rahman K, Qin L-P. 2007. Estrogen-like activity of volatile components from Vitex rotundifolia L. INDIAN JOURNAL OF MEDICAL RESEARCH, 126 :68-72 Author Url

Hismiogullari AA, Bozdayi AM, Rahman K. 2007. Biliary lipid secretion TURKISH JOURNAL OF GASTROENTEROLOGY, 18 :65-70 Author Url

Zhang H, Han T, Yu C-H, Rahman K, Qin L-P, Peng C. 2007. Ameliorating effects of essential oil from Acori graminei rhizoma on learning and memory in aged rats and mice JOURNAL OF PHARMACY AND PHARMACOLOGY, 59 :301-309 DOI Author Url Public Url

Huo Y, Guo C, Zhang Q-Y, Chen W-S, Zheng H-C, Rahman K, Qin L-P. 2007. Antinociceptive activity and chemical composition of constituents from Caragana microphylla seeds PHYTOMEDICINE, 14 :143-146 DOI Author Url

Wu J-Z, Zheng Y-B, Chen T-Q, Yi J, Qin L-P, Rahman K, Lin W-X. 2007. Evaluation of the quality of lotus seed of Nelumbo nucifera Gaertn from outer space mutation FOOD CHEMISTRY, 105 :540-547 DOI Author Url

Han T, Li HL, Hu Y, Zhang QY, Huang BK, Zheng HC, Rahman K, Qin LP. 2006. Phenolic acids in Fructus Xanthii and determination of contents of total phenolic acids in different species and populations of Xanthium in China Journal of Chinese Integrative Medicine, 4 :194-198 DOI Author Url

Gana K, Rahman K, Lowe GM. 2003. Immunomodulation of isolated human neutrophils by a green tea extract Journal of Nutraceuticals, Functional and Medical Foods, 4 :15-26 DOI

Dillon SA, Burmi RS, Lowe GM, Billington D, Rahman K. 2003. Antioxidant properties of aged garlic extract: an in vitro study incorporating human low density lipoprotein. Life Sci, 72 :1583-1594 DOI Author Url

Wang BH, Zuzel KA, Rahman K, Billington D. 1999. Treatment with aged garlic extract protects against bromobenzene toxicity to precision cut rat liver slices. Toxicology, 132 :215-225 DOI Author Url

Wang BH, Zuzel KA, Rahman K, Billington D. 1998. Protective effects of aged garlic extract against bromobenzene toxicity to precision cut rat liver slices. Toxicology, 126 :213-222 DOI Author Url

Rahman K, Billington D, Rigby G. 1997. Cardioprotection and garlic LANCET, 349 :131-131 DOI Author Url

Ernst E, Rahman K, Billington D, Rigby G, Beaglehole R, Myers SP, Smith AJ. 1997. Cardioprotection and garlic (multiple letters) [1] Lancet, 349 :131-132 DOI Author Url

Baxter DJ, Rahman K, Bushell AJ, Mills CO, Elias E, Billington D. 1995. Biliary lipid output by isolated perfused rat livers in response to cholyl-lysylfluorescein. Biochim Biophys Acta, 1256 :374-380 DOI Author Url

Holland RE, Rahman K, Morris AI, Coleman R, Billington D. 1993. Effects of niacin on biliary lipid output in the rat. Biochem Pharmacol, 45 :43-49 DOI Author Url

Coleman R, Rahman K. 1992. Lipid flow in bile formation Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, 1125 :113-133 DOI Author Url

Mills CO, Rahman K, Coleman R, Elias E. 1991. Cholyl-lysylfluorescein: synthesis, biliary excretion in vivo and during single-pass perfusion of isolated perfused rat liver BBA - General Subjects, 1115 :151-156 DOI Author Url

Hamlin S, Rahman K, Carrella M, Coleman R. 1990. Modulation of biliary lipid secretion by forskolin and cyclic AMP analogues Biochemical Journal, 265 :879-885 DOI Author Url

Coleman R, Rahman K, Kan KS, Parslow RA. 1989. Retrograde intrabiliary injection of amphipathic materials causes phospholipid secretion into bile. Taurocholate causes phosphatidylcholine secretion, 3-[(3-cholamidopropyl)dimethylammonio]-propane-1-sulphonate (CHAPS) causes mixed phospholipid secretion Biochemical Journal, 258 :17-22 DOI Author Url

Bellringer ME, Steele NJ, Rahman K, Coleman R. 1988. Ampicillin inhibits the movements of biliary secretory vesicles in rat hepatocytes BBA - Biomembranes, 941 :71-75 DOI Author Url

Bellringer ME, Rahman K, Coleman R. 1988. Sodium valproate inhibits the movement of secretory vesicles in rat hepatocytes Biochemical Journal, 249 :513-519 DOI Author Url

Rahman K, Coleman R. 1987. Effect of chloroquine on biliary lipid and lysosomal enzyme output in the isolated perfused rat liver at low bile salt output rates Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, 922 :395-397 DOI Author Url

Rahman K, Coleman R. 1987. Output of lysosomal contents and cholesterol into bile can be stimulated by taurodehydrocholate Biochemical Journal, 245 :289-292 DOI Author Url

Rahman K, Coleman R. 1987. Biliary lipid secretion and its control. Effect of taurodehydrocholate Biochemical Journal, 245 :531-536 DOI Author Url

Rahman K, Coleman R. 1986. Selective biliary lipid secretion at low bile-salt-output rates in the isolated perfused rat liver. Effects of phalloidin Biochemical Journal, 237 :301-304 DOI Author Url

Billington D, Rahman K, Jones TW, Coleman R, Sykes IR, Aulak KS. 1986. Phospholipid degradation in, and protein content of, rat fistula bile. Contamination of bile with pancreatic juice Journal of Hepatology, 3 :233-240 DOI Author Url

Rahman K, Hammond TG, Lowe PJ, Barnwell SG, Clark B, Coleman R. 1986. Control of biliary phospholipid secretion. Effect of continuous and discontinuous infusion of taurocholate on biliary phospholipid secretion Biochemical Journal, 234 :421-427 DOI

Rahman K, Billington D. 1984. Effect of chenodeoxycholate feeding upon the biliary output of plasma membrane enzymes in the rat Biochemical Pharmacology, 33 :2231-2238 DOI Author Url

Simpson SR, Rahman K, Billington D. 1984. Serum alkaline phosphodiesterase I in experimental biliary obstruction in the rat Clinical Science, 67 :647-652 DOI Author Url

Billington D, Jusczak R, Rahman K. 1983. Chenodeoxycholate feeding increases the output of plasma-membrane marker enzymes into rat bile Biochemical Society Transactions, 11 :162 DOI

Rahman K. Effects of garlic on platelet biochemistry and physiology. Mol Nutr Food Res, 51 :1335-1344 DOI Author Url

Rahman K. Studies on free radicals, antioxidants, and co-factors. Clin Interv Aging, 2 :219-236 Author Url

Rahman K, Lowe GM. Garlic and cardiovascular disease: a critical review. J Nutr, 136 :736S-740S DOI Author Url

Allison GL, Lowe GM, Rahman K. Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms. J Nutr, 136 :782S-788S DOI Author Url

Allison GL, Lowe GM, Rahman K. Aged garlic extract may inhibit aggregation in human platelets by suppressing calcium mobilization. J Nutr, 136 :789S-792S DOI Author Url

El-Sayed MS, Younesian A, Rahman K, Ismail FM, El-Sayed Ali Z. The effects of arm cranking exercise and training on platelet aggregation in male spinal cord individuals. Thromb Res, 113 :129-136 DOI Author Url

Rahman K. Garlic and aging: new insights into an old remedy. Ageing Res Rev, 2 :39-56 DOI Author Url

Dillon SA, Lowe GM, Billington D, Rahman K. Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin F(2 alpha) in smoking and nonsmoking men and women. J Nutr, 132 :168-171 DOI Author Url

Rahman K, Billington D. Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans. J Nutr, 130 :2662-2665 DOI Author Url

Holland RE, Rahman K, Morris AI, Billington D. Effects of niacin on biliary lipid output in the rat. Biochem Soc Trans, 21 :144S DOI Author Url

Chew PY, Riley L, Graham DL, Rahman K, Lowe GM. Does lycopene offer human LDL any protection against myeloperoxidase activity? Mol Cell Biochem, 361 :181-187 DOI Author Url

Zhang X-G, Han T, He Z-G, Zhang Q-Y, Zhang L, Rahman K, Qin L-P. Genetic diversity of Centella asiatica in China analyzed by inter-simple sequence repeat (ISSR) markers: combination analysis with chemical diversity JOURNAL OF NATURAL MEDICINES, 66 :241-247 DOI Author Url

Zheng C-J, Pu J, Zhang H, Han T, Rahman K, Qin L-P. Sesquiterpenoids and norterpenoids from Vitex negundo FITOTERAPIA, 83 :49-54 DOI Author Url

Hu Y, Liu M, Liu P, Guo D-H, Wei R-B, Rahman K. Possible mechanism of the antidepressant effect of 3,6'-disinapoyl sucrose from Polygala tenuifolia Willd. J Pharm Pharmacol, 63 :869-874 DOI Author Url

Jantan I, Jumuddin FA, Saputri FC, Rahman K. Inhibitory effects of the extracts of Garcinia species on human low-density lipoprotein peroxidation and platelet aggregation in relation to their total phenolic contents. Journal of Medicinal Plants Research, 5 :2699-2709 DOI Author Url

Zheng C-J, Lan X-P, Cheng R-B, Huang B-K, Han T, Zhang Q-Y, Zhang H, Rahman K, Qin L-P. Furanofuran lignans from Vitex negundo seeds PHYTOCHEMISTRY LETTERS, 4 :298-300 DOI Author Url

Hu Y, Cao J-J, Liu P, Guo D-H, Wang Y-P, Yin J, Zhu Y, Rahman K. Protective Role of Tea Polyphenols in Combination against Radiation-induced Haematopoietic and Biochemical Alterations in Mice PHYTOTHERAPY RESEARCH, 25 :1761-1769 DOI Author Url

Ma X, Liang J, Zheng C, Hu C, Zhao X, Rahman K, Qin L. Phenylpropanoids from Podocarpium podocarpum PHARMACEUTICAL BIOLOGY, 51 :1021-1025 DOI Author Url

Hismiogullari SE, Hismiogullari AA, Yavuz MT, Yavuz O, Yaman I, Seyrek K, Hayirli A, Rahman K. The Protective Effect of Resveratrol in Experimentally Induced Non-Sterile Clean Wound Inflammation in Rats KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, 19 :A1-A5 DOI Author Url

Shu Z, Pu J, Chen L, Zhang Y, Rahman K, Qin L, Zheng C. Alisma orientale: Ethnopharmacology, Phytochemistry and Pharmacology of an Important Traditional Chinese Medicine. The American journal of Chinese medicine, 44 :227-251 DOI Author Url

Punduk Z, Oral O, Ozkayin N, Rahman K, Varol R. Single dose of intra-muscular platelet rich plasma reverses the increase in plasma iron levels in exercise-induced muscle damage: A pilot study JOURNAL OF SPORT AND HEALTH SCIENCE, 5 :109-114 DOI Author Url Public Url

Conference publication

Punduk Z, Hismiogullari SE, Dogan S, Meric G, Rahman K, Hismiogullari AA. 2017. Effect of platelet rich plasma on antioxidant status in healthy men postexercise-induced muscle damage MEDICINA DELLO SPORT, 70 :551-562 DOI Author Url

Punduk Z, Hismiogullari AA, Rahman K. 2017. AGE SUPPLEMENTATION MODULATES IL-6, IL-10 AND HSP27 RESPONSE IN HEALTHY MEN: EFFECT ON THE MUSCLE STRENGTH Iancheva T, Djobova S, Kuleva M. INTERNATIONAL SCIENTIFIC CONGRESS - APPLIED SPORTS SCIENCES, International Scientific Congress on Applied Sports Sciences :278-283 Author Url

Allison GL, Lowe GM, Rahman K. 2006. Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms Journal of Nutrition, 136

Allison GL, Lowe GM, Rahman K. 2006. Aged garlic extract may inhibit aggregation in human platelets by suppressing calcium mobilization Journal of Nutrition, 136

Rahman K, Lowe GM. 2006. Garlic and cardiovascular disease: A critical review Journal of Nutrition, 136

Lowe GM, Rahman K. 2003. Immunomodulation of isolated neutrophils by a green tea extract. FREE RADICAL RESEARCH, Meeting on Free Radicals and Oxidative Stress 37 :69-69 Author Url

Dillon SA, Lowe GM, Billington D, Rahman K. 2002. Dietary supplementation with aged garlic extract reduces plasma and urinary concentrations of 8-iso-prostaglandins in smokers JOURNAL OF NUTRITION, International Research Conference on Food, Nutrition and Cancer 132 :3549S-3549S Author Url

Rahman K. 2001. Historical perspective on garlic and cardiovascular disease Journal of Nutrition, 131

Rahman K. 2001. Historical perspective on garlic and cardiovascular disease JOURNAL OF NUTRITION, Conference on Recent Advances on the Nutritional Benefits Acaompanying the Use of Garlic as a Supplement 131 :977S-979S DOI Author Url

Omar C, Kamlin F, Parry GCN, Rahman K, Malcolm ADB, Kamalati T, Buluwela L. 1991. Mammalian expression constructs based on the Rous Sarcoma virus LTR in high yield plasmids Biochemical Society Transactions, 19 DOI Author Url

Chapters

Rahman K. 2010. Garlic and heart health Bioactive Foods in Promoting Health :235-244 9780123746283 DOI

Engagement & Impact

Conference presentation:

AGE Supplementation Modulates IL-6, IL-10 and HSP27 Response in Healthy Men: Effect on The Muscle Strength, International Scientific Congress "Applied Sports Sciences", National Sports Academy "Vassil Levski", Sofia, Bulgaria, Poster presentation. 2017

Editorial boards:

Data Sets in Pharmacology, Editorial Board, http://www.datasets.com/journals/pharmacology/guidelines/. 2012

World Journal of Cardiology, Editorial Board, http://www.wjgnet.com/1949-8462/g_info_20100112150908.htm. 2009

Evidence-Based Complementary and Alternative Medicine, Editorial Board.