Dr Nashwa Osman

Pharmacy and Biomolecular Sciences

I have obtained my Doctor of Philosophy (Ph.D.) in nanotoxicology where the evaluation of polymeric nanocarriers for pulmonary drug delivery was carried out using in vitro cell lines, from Liverpool John Mooores University, and entitled 'Toxicology and Cellular Interactions of Polymer-based Nanocarriers for Pulmonary Drug Delivery '. Upon completion of my Ph.D., I have joined the FDD group as a Postdoctoral Research Fellow at Liverpool John Moores University, developing vaccines for inhalation delivery using nanocarriers.

My research is involving many interests from formulations of nanocarriers and microcarriers, drug delivery, toxicology, polymeric materials, cell biology, and toxicology. I have published many conference abstracts and presentations, book chapters, and peer-reviewed research articles. These publications contributed to the science pool by reviewing the up-to-date knowledge regarding the generated nanoparticles types so far, the nanotoxicological potentials of pharmaceutical, environmental, and occupational nanoparticles with a focus on the mucosal contact and pulmonary route of delivery. I had presented many talks and poster presentations to present my findings to the scientific community and challenge some of the commonly employed assays with a recommendation to improve the methods to accommodate for the nanoparticles' interference possibilities. I had provided a few pieces of evidence and cases where nanoparticles' interference with the assays have to be suspected and evaluated.

Degrees:
2000-2008: Bachelor’s degree in Medicine & Surgery- Excellent Degree with honor Faculty of Medicine, Sohag University, Eygpt
2010-2012: Master’s degree in Forensic medicine & Clinical Toxicology- Excellent Degree, Faculty of Medicine, Sohag University, Eygpt
2016-2020: PhD in Nanotoxicology, LJMU
2020-Present: Postdoctoral Research Fellow in LJMU

Languages

Arabic
English

Degrees

2020, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK, Doctor Of Philosophy
2012, Faculty of Medicine, Sohag University, Egypt, Egypt, Master’s degree in Clinical Nanotoxicology-
2008, Faculty of Medicine, Sohag University, Egypt, Egypt, Bachelor’s degree in Medicine & Surgery

Academic appointments

Postdoctoral Research Fellow, Liverpool John Moores University, 2021 - present
Research Assistant, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, 2020 - 2021
Teaching Assistant Officer, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, 2016 - 2019
Biology Tutor, International Study Center- Liverpool John Moores University, 2016 - present
Research Visitor, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, 2014 - 2016
Assistant Lecturer, Faculty Of Medicine, Sohag University, 2012 - 2014
Demonstrator, Faculty of Medicine, Sohag University, 2008 - 2012

Chapters

Kaneko K, Osman N, Carini V, Scagnetti G, Saleem I. 2020. Overview of the Advantages and Disadvantages of Different Mucosal Sites for the Delivery of Nanoparticles Muttil P, kunda N. Mucosal Delivery of Drugs and Biologics in Nanoparticles 41 Springer Nature. Switzerland 9783030359102 DOI Publisher Url Public Url

Journal article

Osman NM, Sexton DW, Saleem IY. 2019. Toxicological assessment of nanoparticle interactions with the pulmonary system Nanotoxicology, DOI Author Url Publisher Url Public Url

Osman N, Kaneko K, Carini V, Saleem I. 2018. Carriers for the Targeted Delivery of Aerosolized Macromolecules for Pulmonary Pathologies. Expert Opin Drug Deliv, DOI Author Url Public Url

Basar N, Oridupa OA, Ritchie KJ, Nahar L, Osman NMM, Stafford A, Kushiev H, Kan A, Sarker SD. 2015. Comparative Cytotoxicity of Glycyrrhiza glabra Roots from Different Geographical Origins Against Immortal Human Keratinocyte (HaCaT), Lung Adenocarcinoma (A549) and Liver Carcinoma (HepG2) Cells PHYTOTHERAPY RESEARCH, 29 :944-948 DOI Author Url Public Url

Conference publication

Osman N, Sexton D, Hutcheon G, Saleem I. 2017. COMPARATIVE NANOTOXICOLOGY OF POLYMERIC NANOCARRIERS WITH DIFFERENT SURFACE CHARGE AGAINST HUMAN LUNG EPITHELIAL CELLS JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 30 :A17-A18 Author Url

Scagnetti G, Verhook S, Killoran P, Coxon C, Osman N, Gordon S, Chaudary S, Saleem I. Antimicrobial Activity of Peptide Aurein 3.1 Complexed in Chitosan Nanoparticle for Pulmonary Delivery - 11th PBP World Meeting

Thesis/Dissertation

Mostafa Mahmoud Osman N. Toxicology and Cellular Interactions of Polymer-based Nanocarriers for Pulmonary Drug Delivery Saleem I, Sexton D. Public Url

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