Marks PhD studies will explore cellular and molecular mechanisms behind skeletal muscle adaptation in response to hypertrophy, atrophy and regeneration using rodent models.
Marks particular interests include myonuclei and the regulation of muscle growth and muscle loss through mechanical forces transfer
Supervisors: Prof. Jonathan C Jarvis, Prof. Claire Stewart, Dr. Daniel Owens
Liverpool John Moores University, UK, BSc (Hons) Sport and Exercise Sciences (Physiology)
Liverpool John Moores University, United Kingdom, MPhil, Cell and Molecular Exercise Physiology
Turner DC, Gorski PP, Seaborne RA, Viggars M, Murphy M, Jarvis JC, Martin NRW, Stewart CE, Sharples AP. 2021. Mechanical loading of bioengineered skeletal muscle in vitro recapitulates gene expression signatures of resistance exercise in vivo. Journal of Cellular Physiology, DOI Author Url Publisher Url Public Url
Owens DJ, Messeant J, Moog S, Viggars M, Ferry A, Mamchaoui K, Lacene E, Romero N, Brull A, Bonne G, Butler-Browne G, Coirault C. 2021. Lamin-Related Congenital Muscular Dystrophy Alters Mechanical Signaling and Skeletal Muscle Growth INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22 DOI Author Url Public Url
Turner D, Hughes D, Seaborne R, Viggars M, Jarvis J, Gorski P, Stewart C, Owens D, Bodine S, Sharples A. 2021. Knockdown of the E3 Ubiquitin ligase UBR5 and its role in skeletal muscle anabolism American Journal of Physiology: Cell Physiology, 320 :C45-C56 DOI Author Url Publisher Url Public Url
Seaborne RA, Viggars M, Sharples AP. 2019. HOW LONG DOES MUSCLE MEMORY LAST? THE ROLE OF EPIGENETICS JOURNAL OF APPLIED PHYSIOLOGY, 127 :1819-1819 Author Url
Editorial/letter to the editor
Viggars M, Jarvis J. 2018. Intracellular signalling responses following loaded contractions in murine skeletal muscle induced by programmed exercise: Hypertrophy or hyperplasia? GJSEPER, BASES Conference 2018 8 :S25-S25
Viggars M, Stewart C, Brown A. 2017. Impact of HIIT at sea level vs. simulated altitude on endurance and strength gains: A potential role for stem cell mobilisation British Association of Sport & Exercise Sciences (BASES) 2017 Student Conference 5 :S108-S108
Viggars M. MYONUCLEAR APOPTOSIS DOES NOT OCCUR FOLLOWING SHORT TERM ATROPHY Liverpool Muscle Meeting (Poster)
LJMU Tom Reilly Award, https://www.ljmu.ac.uk/about-us/news/articles/2017/7/10/graduation-2017-monday. 2017
https://www.physoc.org/magazine-articles/future-physiology-2019-uniting-early-career-researchers-2/, Future Physiology 2019: Uniting early career researchers https://doi.org/10.36866/pn.116.20.