Liverpool Skylilne

Sport and Exercise Sciences

Dr Nicola Hopkins

Dr Nicola Hopkins

Telephone: 0151 904 6271

Biography

Nicola is a Lecturer/Senior Lecturer in Exercise and cardiovascular physiology in the School of Sport and Exercise Sciences, and is a member of the Cardiovascular Research Group within the Research Institute of Sport and Exercise Sciences (RISES). Nicola's research interests are focussed on understanding the vascular responses to physical activity and sedentary behaviour in a range of healthy and clinical groups.

Degrees

2010, Liverpool John Moores University, United Kingdom, PhD 'The determinants of vascular health in young people'
Liverpool John Moores University, United Kingdom, MSc Exercise Physiology
Liverpool John Moores University, United Kingdom, BSc (hons) Sport and Exercise Science (Physiology)

Publications

Highlighted publications

Tinken TM, Thijssen DHJ, Hopkins N, Black MA, Dawson EA, Minson CT, Newcomer SC, Laughlin MH, Cable NT, Green DJ. 2009. Impact of shear rate modulation on vascular function in humans. Hypertension, 54 :278-285 >DOI >Link

Journal Articles

Boddy LM, Cunningham C, Fairclough SJ, Murphy MH, Breslin G, Foweather L, Dagger RM, Graves LEF, Hopkins ND, Stratton G. 2017. Individual calibration of accelerometers in children and their health-related implications Journal of Sports Sciences, :1-6 >DOI

Roberts KA, van Gent T, Hopkins ND, Jones H, Dawson EA, Draijer R, Carter HH, Atkinson CL, Green DJ, Thijssen DHJ, Low DA. 2017. Reproducibility of four frequently used local heating protocols to assess cutaneous microvascular function MICROVASCULAR RESEARCH, 112 :65-71 >DOI >Link

Carter S, Hartman Y, Holder S, Thijssen DH, Hopkins ND. 2017. Sedentary Behavior and Cardiovascular Disease Risk: Mediating Mechanisms EXERCISE AND SPORT SCIENCES REVIEWS, 45 :80-86 >DOI >Link

van Mil ACCM, Hartman Y, van Oorschot F, Heemels A, Bax N, Dawson EA, Hopkins N, Hopman MTE, Green DJ, Oxborough DL, Thijssen DHJ. 2017. Correlation of carotid artery reactivity with cardiovascular risk factors and coronary artery vasodilator responses in asymptomatic, healthy volunteers JOURNAL OF HYPERTENSION, 35 :1026-1034 >DOI >Link

Buchan DS, Boddy LM, Grace FM, Brown E, Sculthorpe N, Cunningham C, Murphy MH, Dagger R, Foweather L, Graves LEF, Hopkins ND, Stratton G, Baker JS. 2017. Utility of three anthropometric indices in assessing the cardiometabolic risk profile in children AMERICAN JOURNAL OF HUMAN BIOLOGY, 29 >DOI >Link

Woodward KA, Hopkins ND, Draijer R, de Graaf Y, Low DA, Thijssen DHJ. 2016. Acute black tea consumption improves cutaneous vascular function in healthy middle-aged humans Clinical Nutrition, >DOI

Fussenich LM, Boddy LM, Green DJ, Graves LEF, Foweather L, Dagger RM, McWhannell N, Henaghan J, Ridgers ND, Stratton G, Hopkins ND. 2016. Physical activity guidelines and cardiovascular risk in children: a cross sectional analysis to determine whether 60 minutes is enough BMC PUBLIC HEALTH, 16 >DOI >Link

Green DJ, Hopkins ND, Jones H, Thijssen DHJ, Eijsvogels TMH, Yeap BB. 2016. Sex differences in vascular endothelial function and health in humans: impacts of exercise EXPERIMENTAL PHYSIOLOGY, 101 :230-242 >DOI >Link

Graves LEF, Murphy RC, Shepherd SO, Cabot J, Hopkins ND. 2015. Evaluation of sit-stand workstations in an office setting: a randomised controlled trial BMC PUBLIC HEALTH, 15 >DOI >Link

Woodward KA, Unnithan V, Hopkins ND. 2015. Forearm Skin Blood Flow After Kinesiology Taping in Healthy Soccer Players: An Exploratory Investigation JOURNAL OF ATHLETIC TRAINING, 50 :1069-1075 >DOI >Link

Hopkins ND, Dengel DR, Stratton G, Kelly AS, Steinberger J, Zavala H, Marlatt K, Perry D, Naylor LH, Green DJ. 2015. Age and sex relationship with flow-mediated dilation in healthy children and adolescents JOURNAL OF APPLIED PHYSIOLOGY, 119 :926-933 >DOI >Link

Jones H, Nyakayiru J, Bailey TG, Green DJ, Cable NT, Sprung VS, Hopkins ND, Thijssen DHJ. 2015. Impact of eight weeks of repeated ischaemic preconditioning on brachial artery and cutaneous microcirculatory function in healthy males EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY, 22 :1083-1087 >DOI >Link

Konidari A, Auth MKH, Murphy MH, Cunningham C, Foweather L, Gobbi R, Graves LEF, Hopkins ND, Stratton G, Boddy LM. 2014. Assessment of biochemical liver markers, physical activity, fitness and body mass index for a cardiometabolic risk model in childhood ACTA PAEDIATRICA, 103 :E194-E198 >DOI >Link

Boddy LM, Murphy MH, Cunningham C, Breslin G, Foweather L, Gobbi R, Graves LEF, Hopkins ND, Auth MKH, Stratton G. 2014. Physical Activity, Cardiorespiratory Fitness, and Clustered Cardiometabolic Risk in 10-to 12-year-old School Children: The REACH Y6 Study AMERICAN JOURNAL OF HUMAN BIOLOGY, 26 :446-451 >DOI >Link

Jones H, Hopkins N, Bailey TG, Green DJ, Cable NT, Thijssen DHJ. 2014. Seven-Day Remote Ischemic Preconditioning Improves Local and Systemic Endothelial Function and Microcirculation in Healthy Humans AMERICAN JOURNAL OF HYPERTENSION, 27 :918-925 >DOI >Link

Hopkins ND, Cuthbertson DJ, Kemp GJ, Pugh C, Green DJ, Cable NT, Jones H. 2013. Effects of 6 months glucagon-like peptide-1 (GLP-1) receptor agonists treatment on endothelial function in patients type 2 diabetes mellitus Diabetes, Obesity and Metabolism,

Graves LEF, Batterham AM, Foweather L, Mcwhannell N, Hopkins ND, Boddy LM, Gobbi R, Stratton G. 2013. Scaling of peak oxygen uptake in children: A comparison of three body size index models Medicine and Science in Sports and Exercise, 45 :2341-2345 >DOI

Hopkins ND, Cuthbertson DJ, Kemp GJ, Pugh C, Green DJ, Cable NT, Jones H. 2013. Effects of 6months glucagon-like peptide-1 receptor agonist treatment on endothelial function in type 2 diabetes mellitus patients Diabetes, Obesity and Metabolism, 15 :770-773 >DOI

Hopkins ND, van den Munckhof I, Thijssen DHJ, Tinken TM, Cable NT, Stratton G, Green DJ. 2013. Are changes in conduit artery function associated with intima-medial thickness in young subjects? Eur J Prev Cardiol, 20 :904-910 >DOI >Link

Hopkins ND, Stratton G, Cable NT, Tinken TM, Graves LEF, Green DJ. 2012. Impact of exercise training on endothelial function and body composition in young people: a study of mono- and di-zygotic twins. Eur J Appl Physiol, 112 :421-427 >DOI >Link

Naylor LH, Green DJ, Jones TW, Kalic RJ, Suriano KL, Shah M, Hopkins ND, Davis EA. 2011. Endothelial function and carotid intima-medial thickness in adolescents with type 2 diabetes Journal of Pediatrics, 159 :971-974

Hopkins ND, Stratton G, Cable NT, Tinken TM, Graves LEF, Green DJ. 2011. Impact of exercise training on endothelial function and body composition in young people: a study of mono- and di-zygotic twins European Journal of Applied Physiology, :1-7

Naylor LH, Green DJ, Jones TW, Kalic RJ, Suriano KL, Shah M, Hopkins N, Davis EA. 2011. Endothelial function and carotid intima-medial thickness in adolescents with type 2 diabetes mellitus. J Pediatr, 159 :971-974 >DOI >Link

Thijssen DHJ, Dawson EA, van den Munckhof ICL, Tinken TM, den Drijver E, Hopkins N, Cable NT, Green DJ. 2011. Exercise-mediated changes in conduit artery wall thickness in humans: role of shear stress. Am J Physiol Heart Circ Physiol, 301 :H241-H246 >DOI >Link

Hopkins ND, Stratton G, Tinken TM, Ridgers ND, Graves LE, McWhannell N, Cable NT, Green DJ. 2011. Seasonal reduction in physical activity and flow-mediated dilation in children. Med Sci Sports Exerc, 43 :232-238 >DOI >Link

Thijssen DHJ, Tinken TM, Hopkins N, Dawson EA, Cable NT, Green DJ. 2011. The impact of exercise training on the diameter dilator response to forearm ischaemia in healthy men. Acta Physiol (Oxf), 201 :427-434 >DOI >Link

Hopkins ND, Stratton G, Maia J, Tinken TM, Graves LEF, Cable NT, Green DJ. 2010. Heritability of Arterial Function, Fitness, and Physical Activity in Youth: A Study of Monozygotic and Dizygotic Twins The Journal of Pediatrics, :943-948 >DOI

Hopkins N, Stratton G, Maia J, Tinken TM, Graves LE, Cable TN, Green DJ. 2010. Heritability of arterial function, fitness, and physical activity in youth: a study of monozygotic and dizygotic twins. J Pediatr, 157 :943-948 >DOI >Link

Hopkins ND, Green DJ, Tinken TM, Sutton L, McWhannell N, Cable NT, Stratton G, George K. 2010. Does brachial artery flow-mediated dilation scale to anthropometric characteristics? Eur J Appl Physiol, 110 :171-176 >DOI >Link

Tinken TM, Thijssen DHJ, Hopkins N, Dawson EA, Cable NT, Green DJ. 2010. Shear stress mediates endothelial adaptations to exercise training in humans. Hypertension, 55 :312-318 >DOI >Link

Hopkins ND, Stratton G, Tinken TM, McWhannell N, Ridgers ND, Graves LEF, George K, Cable NT, Green DJ. 2009. Relationships between measures of fitness, physical activity, body composition and vascular function in children. Atherosclerosis, 204 :244-249 >DOI >Link

Hopkins ND, Green DJ, Tinken TM, Sutton L, McWhannell N, Thijssen DHJ, Cable NT, Stratton G, George K. 2009. Does conduit artery diameter vary according to the anthropometric characteristics of children or men? Am J Physiol Heart Circ Physiol, 297 :H2182-H2187 >DOI >Link

Atkinson G, Batterham AM, Black MA, Cable NT, Hopkins ND, Dawson EA, Thijssen DHJ, Jones H, Tinken TM, Green DJ. 2009. Is the ratio of flow-mediated dilation and shear rate a statistically sound approach to normalization in cross-sectional studies on endothelial function? J Appl Physiol (1985), 107 :1893-1899 >DOI >Link

Tinken TM, Thijssen DHJ, Hopkins N, Black MA, Dawson EA, Minson CT, Newcomer SC, Laughlin MH, Cable NT, Green DJ. 2009. Impact of shear rate modulation on vascular function in humans. Hypertension, 54 :278-285 >DOI >Link

Thijssen DHJ, Bullens LM, van Bemmel MM, Dawson EA, Hopkins N, Tinken TM, Black MA, Hopman MTE, Cable NT, Green DJ. 2009. Does arterial shear explain the magnitude of flow-mediated dilation?: a comparison between young and older humans. Am J Physiol Heart Circ Physiol, 296 :H57-H64 >DOI >Link

Dawson EA, Black MA, Jones H, Hopkins N, Shave R, George KP, Wilson M, Whyte G, Green DJ. 2008. Impact Of The London Marathon On Brachial Artery Flow-Mediated Vasodilation MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 40 :S90-S91 >DOI >Link

Thijssen DHJ, van Bemmel MM, Bullens LM, Dawson EA, Hopkins ND, Tinken TM, Black MA, Hopman MTE, Cable NT, Green DJ. 2008. The impact of baseline diameter on flow-mediated dilation differs in young and older humans. Am J Physiol Heart Circ Physiol, 295 :H1594-H1598 >DOI >Link

Dawson EA, Whyte GP, Black MA, Jones H, Hopkins N, Oxborough D, Gaze D, Shave RE, Wilson M, George KP, Green DJ. 2008. Changes in vascular and cardiac function after prolonged strenuous exercise in humans. J Appl Physiol (1985), 105 :1562-1568 >DOI >Link

Hopkins ND, van den Munckhof I, Thijssen DHJ, Tinken TM, Cable NT, Stratton G, Green DJ. Are changes in conduit artery function associated with intima-medial thickness in young subjects? European Journal of Preventive Cardiology, >DOI

Hopkins ND, Stratton G, Tinken TM, Graves LEF, Cable NT, Green DJ. Impact of exercise training on endothelial function, and fitness in young people: A study of mono- and di-zygotic twins. European Journal of Applied Physiology, >Link

Hopkins N, Stratton G, Tinken TM, Ridgers N, Graves LEF, McWhannell N, Cable NT, Green DJ. Seasonal Reduction in Physical Activity and Flow Mediated Dilation in Children. Medicine and Science in Sports and Exercise,

Houston EL, Baker JS, Buchan DS, Stratton G, Fairclough SJ, Foweather L, Gobbi R, Graves LEF, Hopkins ND, Boddy LM. Cardiorespiratory fitness predicts clustered cardiometabolic risk in 10-11.9 year olds European Journal of Pediatrics,

Hopkins ND, Stratton G, Tinken TM, Ridgers ND, Graves LEF, Cable NT, Green DJ. Lack of relationship between sedentary behaviour and vascular health in children European Journal of Applied Physiology, >Link

Other

Carter SE, Draijer R, Holder SM, Thijssen DHJ, Hopkins ND. 2016. The Effect of Breaking up Prolonged Sitting on Cerebral Blood Flow MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 48 :311-311 >DOI >Link

Conference Publication (journal proceedings)

Hopkins ND, Green DJ, Dawson EA, Jones H. 2016. The Acute Effect Of High Intensity Interval Exercise And Moderate Continuous Exercise On Endothelial Function In Children. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, Annual Meeting of the American-College-of-Sports-Medicine (ACSM) 48 :190-190 >DOI >Link

Hopkins ND, Stratton G, Ridgers N, Graves LEF, Foweather L, Boddy LM, Gobbi R, Cable NT, Green DJ. Associations between sedentary behaviour, cardiometabolic biomarkers and vascular health in children ACSM

Hopkins ND, van den Munckhof I, Thijssen DHJ, Tinken TM, Cable NT, Stratton G, Green DJ. Does conduit artery function predict intima-medial thickness in young subjects? Institute for Health Research Conference

Hopkins ND, Stratton G, Tinken TM, Graves LEF, Cable NT, Green DJ. Are exercise induced changes in arterial function genetically determined? A study of mono- and di-zygotic twins European College of Sports Science

Hopkins ND, Stratton G, Ridgers ND, Graves LEF, Foweather L, Cable NT, Green DJ. Sedentary behaviour or physical activity: What’s important for vascular health in children? European College of Sports Science

Hopkins ND, Stratton G, Ridgers ND, Graves LEF, Boddy LM, Gobbi R, Foweather L, Cable NT, Green DJ. No association between sedentary behaviour and vascular health in children Paediatric Work Physiology European Congress

Engagement & Impact

Award:

Award title: Young Investigator Award, Awarding body: Paediatric Work Physiology Congress

External collaboration:

Institution: Staffordshire University, Collaborator: Professor Vish Unnithan

Institution: University of Minnesota, Collaborator: Professor Donald Dengel

Institution: University of Ulster Sport and Exercise Sciences Research Institute, Collaborator: Professor Marie Murphy

Research Grants Awarded:

Unilever, The effects of tea consumption on microcirculatory function, Dick Thijssen, Dave Low, Grant value (£): 40000, Duration of research project: 1 year mphil with option to progress to PhD

Liverpool John Moores University ECR Fellowship scheme, Visit to Baker Institute, Grant value (£): £3125, Duration of research project: 3 weeks

Biotechnology and Biological Sciences Research Council - Industrial CASE studentship awards, Breaking sedentary behaviour to build up brains - Reducing workplace sedentary behaviour to improve work related mental performance, Dick Thijssen, Anton Wagenmakers, Grant value (£): £200000, Duration of research project: 4 years

The British Medical Association The Overweight & Heart Disease Research Trust, Liver disease in obese adolescents: an investigation into the physiological effects of exercise training, Dr Laurence Abernethy and Dr Marcus Auth Alder Hey Children's NHS Trust. Dr Helen Jones and Prof Tim Cable LJMU., Grant value (£): £10 000, Duration of research project: 1 year

The Childrens Liver Disease Foundation, Determinants of paediatric Non-Alcoholic Fatty Liver Disease in obese adolescents, Dr Helen Jones Professor Tim Cable LJMU. Dr Laurence Abernethy and Dr Marcus Auth Alder Hey Children's NHS Trust, Grant value (£): £5000, Duration of research project: 6 months