Monitoring exercise

Resistance training with vitamin C-enriched collagen study

Take part in our study

The effect of resistance training with vitamin C-enriched collagen supplementation on changes in muscle and tendon properties in young healthy men and women

Like skeletal muscle, tendon also adapts in response to resistance exercise and nutrition. Although an acute bout of exercise with collagen intake increase markers of collagen synthesis, the long-term effect of resistance training with collagen intake on tendon adaptation is unknown. Therefore, the aim of study is to investigate how tendon and muscle adapt in response to 10-week resistance training with collagen supplementation in young men and women.

I'm looking to recruit participants to take part in 10-week supervised resistance training.

You will be eligible to take part in this study if you are a healthy male or female:

  • Age 18-39 years
  • No history of patellar and Achilles tendon injuries in the past 6 months
  • No history of lower limb musculoskeletal injuries in the past 6 months
  • Nullipara (a woman who has never given birth) for young women
  • Use of oral contraceptive pills for at least 6 months (only young women)
  • Non-smokers (including e-cigarettes)
  • Free from cardiovascular and metabolic diseases

As collagen is derived from mammals and fish, vegans and vegetarians will not be able to participate in this study.

If you would like to offer your time for this important research project you will be asked to visit the laboratory for 4 – 6 times and undertake 10-week resistance training.

Infographic - Collagen study

Figure 1. An overview of the study intervention periods and measurements. MTU, muscle-tendon unit assessment; Fat, percentage of body fat measurement; 10-RM, 10-repetition maximum.

As you can see in Figure 1, the 1st visit is the familiarization session. Maximal strength, muscle and tendon properties (the lower limb) and percentage of body fat will be measured. 10-repetition maximum (10-RM) test measures the load you can lift for 10 repetitions, which will be used in an acute experiment and training load for 10-week training (midpoint and post-training tests are the same as the baseline test).

During the 2nd visit, you will consume collagen intake and perform a bout of resistance exercise. After completion of the exercise, you will rest for 6 hours in a laboratory. Multiple 5 ml samples of blood will be drawn during this experiment.

The 10-week resistance training program is composed of whole-body exercises: leg press, leg curl, barbell calf raise and one exercise for each chest and back. Training frequency is 3 times per week and its intensity is 5 sets of 10 repetitions at 10-RM load. Immediately after resistance exercise, collagen supplementation will be given.

Full details of the study can be found in the participant information sheet. Please feel free to read this information and should you wish to take part, or if you have any further questions, please contact Joonsung Lee.

This study has been approved by the University Research Ethics Committee with reference 19/SPS/054.