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Department of Applied Mathematics

Dr Gabriela Czanner

Dr Gabriela Czanner

Telephone: 0151 231 8038

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Biography

My research group: https://gczanner.wordpress.com/

Gabriela is a Senior Lecturer in Statistics and Data Science at Department of Applied Mathematics at Liverpool John Moores University. Her research focus is advanced statistics for decision support, in particular with applications to personalised medicine, public health, ophthalmology, neuroscience, cancer epidemiology and medical imaging. Her research group has developed statistical methods for diagnosis of glaucoma from retinal images. She has worked as a Lecturer at University of Liverpool (2012-2018), Postdoctoral Research Fellow at University of Warwick (2010-2012, 2007-2008), University of Oxford (2009-2010), Harvard Medical School and Massachusetts General Hospital (2004-2007). She obtained PhD in Statistics at University of Pittsburgh, USA (2004), MA in Economics at University of Pittsburgh, USA (1999) and MSc in Mathematical Statistics, Probability and Computer Science at Comenius University in Slovakia, 1994.

The primary aim of research in the ophthalmic statistics group is the development of the novel methodology to design and analyses ophthalmic studies. Currently we are addressing a number of key challenges in inference and prediction from observational studies that contain images collected from retina or cornea. Current research projects include:
1) Spatial statistical models clinical images toward understanding of ophthalmic diseases.
2) Longitudinal and spatio-temporal models for early detection, screening and monitoring of diseases.
3) Signal-to-noise ratio metrics for evaluation of the signal in the complex data and for feature extraction.

We are always looking for new students to work on exciting projects. Please send any enquiries via email or Twitter (see above).

Languages

Slovak

Degrees

2004, University of Pittsburgh, USA, PhD in Statistics

Publications

Journal article

Grayston R, Czanner G, Elhadd K, Goebel A, Frank B, Uceyler N, Malik RA, Alam U. 2019. A systematic review and meta-analysis of the prevalence of small fiber pathology in fibromyalgia: Implications for a new paradigm in fibromyalgia etiopathogenesis SEMINARS IN ARTHRITIS AND RHEUMATISM, 48 :933-940 >DOI >Link

MacCormick IJC, Williams BM, Zheng Y, Li K, Al-Bander B, Czanner S, Cheeseman R, Willoughby CE, Brown EN, Spaeth GL, Czanner G. 2019. Accurate, fast, data efficient and interpretable glaucoma diagnosis with automated spatial analysis of the whole cup to disc profile PLOS ONE, 14 :e0209409-e0209409 >DOI >Public Url

Vinciguerra R, Rehman S, Vallabh NA, Batterbury M, Czanner G, Choudhary A, Cheeseman R, Elsheikh A, Willoughby CE. 2019. Corneal biomechanics and biomechanically corrected intraocular pressure in primary open-angle glaucoma, ocular hypertension and controls British Journal of Ophthalmology, >DOI

MacCormick IJC, Williams BM, Zheng Y, Li K, Al-Bander B, Czanner S, Cheeseman R, Willoughby CE, Brown EN, Spaeth GL, Czanner G. 2019. Accurate, fast, data efficient and interpretable glaucoma diagnosis with automated spatial analysis of the whole cup to disc profile (vol 14, e0209409, 2019) PLOS ONE, 14 >DOI >Link

Lourenco EAJ, Shaw L, Pratt H, Duffy GL, Czanner G, Zheng Y, Hamill KJ, McCormick AG. 2019. Application of SPF moisturisers is inferior to sunscreens in coverage of facial and eyelid regions PLOS ONE, 14 >DOI >Link

Bunce C, Stratton IM, Elders A, Czanner G, Dore C, Freemantle N. 2019. Ophthalmic statistics note 13: method agreement studies in ophthalmology-please don't carry on correlating horizontal ellipsis BRITISH JOURNAL OF OPHTHALMOLOGY, 103 :1201-1203 >DOI >Link

Brunner M, Czanner G, Vinciguerra R, Romano V, Ahmad S, Batterbury M, Britten C, Willoughby CE, Kaye SB. 2018. Improving precision for detecting change in the shape of the cornea in patients with keratoconus Scientific Reports, 8 >DOI >Link >Public Url

Mandourah AY, Ranganath L, Barraclough R, Vinjamuri S, Van'T Hof R, Hamill S, Czanner G, Dera AA, Wang D, Barraclough DL. 2018. Circulating microRNAs as potential diagnostic biomarkers for osteoporosis SCIENTIFIC REPORTS, 8 >DOI >Link

Brunner M, Romano V, Steger B, Vinciguerra R, Lawman S, Williams B, Hicks N, Czanner G, Zheng Y, Willoughby CE, Kaye SB. 2018. Imaging of Corneal Neovascularization: Optical Coherence Tomography Angiography and Fluorescence Angiography INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 59 :1263-1269 >DOI >Link

Roy IN, Chan TY, Czanner G, Wallace S, Vallabhaneni SR. 2018. Prospective, single UK centre, comparative study of the predictive values of contrast-enhanced ultrasound compared to time-resolved CT angiography in the detection and characterisation of endoleaks in high risk patients undergoing endovascular aneurysm repair surveillance: a protocol BMJ OPEN, 8 >DOI >Link

Barrera V, MacCormick IJC, Czanner G, Hiscott PS, White VA, Craig AG, Beare NAV, Culshaw LH, Zheng Y, Biddolph SC, Milner DA, Kamiza S, Molyneux ME, Taylor TE, Harding SP. 2018. Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina ELIFE, 7 >DOI >Link

Hughes DM, Komarek A, Czanner G, Garcia-Finana M. 2018. Dynamic longitudinal discriminant analysis using multiple longitudinal markers of different types STATISTICAL METHODS IN MEDICAL RESEARCH, 27 :2060-2080 >DOI >Link

Smolkova B, Kajabova VH, Zmetakova I, Kalinkova L, Czanner G, Markova A, Furdova A. 2018. Role of epigenetic deregulation in hematogenous dissemination of malignant uveal melanoma NEOPLASMA, 65 :840-854 >DOI >Link

Hughes DM, Bonnett LJ, Czanner G, Komarek A, Marson AG, Garcia-Finana M. 2018. Identification of patients who will not achieve seizure remission within 5 years on AEDs NEUROLOGY, 91 :E2035-E2044 >DOI >Link

Vazquez NP, Harding SP, Heimann H, Czanner G, Knox PC. 2018. Radial shape discrimination testing for new-onset neovascular age-related macular degeneration in at-risk eyes PLOS ONE, 13 >DOI >Link

MacCormick IJC, Zheng Y, Czanner S, Zhao Y, Diggle PJ, Harding SP, Czanner G. 2017. Spatial statistical modelling of capillary non-perfusion in the retina SCIENTIFIC REPORTS, 7 >DOI >Link >Public Url

Pratt H, Hassanin K, Troughton LD, Czanner G, Zheng Y, McCormick AG, Hamill KJ. 2017. UV imaging reveals facial areas that are prone to skin cancer are disproportionately missed during sunscreen application PLOS ONE, 12 >DOI >Link

Bunce C, Czanner G, Grzeda MT, Dore CJ, Freemantle N. 2017. Ophthalmic statistics note 12: multivariable or multivariate: what's in a name? BRITISH JOURNAL OF OPHTHALMOLOGY, 101 :1303-1305 >DOI >Link

Hughes DM, Komarek A, Bonnett LJ, Czanner G, Garcia-Finana M. 2017. Dynamic classification using credible intervals in longitudinal discriminant analysis STATISTICS IN MEDICINE, 36 :3858-3874 >DOI >Link

Steptoe PJ, Scott JT, Baxter JM, Parkes CK, Dwivedi R, Czanner G, Vandy MJ, Momorie F, Fornah AD, Komba P, Richards J, Sahr F, Beare NAV, Semple MG. 2017. Novel Retinal Lesion in Ebola Survivors, Sierra Leone, 2016 EMERGING INFECTIOUS DISEASES, 23 :1102-1109 >DOI >Link

Chan YK, Lu Y, Czanner G, Wu J, Cheng HC, Hussain R, Sakamoto T, Shum HC, Wong D. 2017. In vitro experiment to elucidate the mechanism of the "soft shell technique' for preventing subretinal migration of perfluoro-octane BRITISH JOURNAL OF OPHTHALMOLOGY, 101 :389-394 >DOI >Link

Sahni JN, Czanner G, Gutu T, Taylor SA, Bennett KM, Wuerger SM, Grierson I, Murray-Dunning C, Holland MN, Harding SP. 2017. Safety and acceptability of an organic light-emitting diode sleep mask as a potential therapy for retinal disease EYE, 31 :98-105 >DOI >Link

Ho VWM, Hussain RN, Czanner G, Sen J, Heimann H, Damato BE. 2017. Porous Versus Nonporous Orbital Implants After Enucleation for Uveal Melanoma: A Randomized Study OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY, 33 :452-458 >DOI >Link

Chan YK, Czanner G, Shum HC, Williams RL, Cheung N, Wong D. 2017. Towards better characterization and quantification of emulsification of silicone oil invitro ACTA OPHTHALMOLOGICA, 95 :E385-E392 >DOI >Link

Sahni JN, Czanner G, Gutu T, Taylor SA, Bennett KM, Wuerger SM, Grierson I, Murray-Dunning C, Holland MN, Harding SP. 2017. Safety and acceptability of an organic light-emitting diode sleep mask as a potential therapy for retinal disease EYE, 31 :106-106 >Link

Sahni JN, Czanner G, Gutu T, Taylor SA, Bennett KM, Wuerger SM, Grierson I, Murray-Dunning C, Holland MN, Harding SP. 2017. Safety and acceptability of an organic lightemitting diode sleep mask as a potential therapy for retinal disease EYE, 31 :97-97 >DOI >Link

Silvester A, Neal T, Czanner G, Briggs M, Harding S, Kaye S. 2016. Adult bacterial conjunctivitis: Resistance patterns over 12 years in patients attending a large primary eye care centre in the UK BMJ Open Ophthalmology, 1 >DOI

Knox PC, MacCormick IJC, Mbale E, Malewa M, Czanner G, Harding SP. 2016. Longitudinal Visuomotor Development in a Malaria Endemic Area: Cerebral Malaria and Beyond PLOS ONE, 11 >DOI >Link

Vallabh NA, Sahni JN, Parkes CK, Czanner G, Heimann H, Damato B. 2016. Near-infrared reflectance and autofluorescence imaging characteristics of choroidal nevi EYE, 30 :1593-1597 >DOI >Link

Aslam TM, Tahir HJ, Parry NRA, Murray IJ, Kwak K, Heyes R, Salleh MM, Czanner G, Ashworth J. 2016. Automated Measurement of Visual Acuity in Pediatric Ophthalmic Patients Using Principles of Game Design and Tablet Computers AMERICAN JOURNAL OF OPHTHALMOLOGY, 170 :223-227 >DOI >Link

Tidbury LP, Czanner G, Newsham D. 2016. Fiat Lux: the effect of illuminance on acuity testing GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 254 :1091-1097 >DOI >Link

Aslam TM, Parry NRA, Murray IJ, Salleh M, Dal Col C, Mirza N, Czanner G, Tahir HJ. 2016. Development and testing of an automated computer tablet-based method for self-testing of high and low contrast near visual acuity in ophthalmic patients GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 254 :891-899 >DOI >Link

Mittal R, Araujo I, Czanner G, Coupland SE. 2016. Perforin expression in eyelid sebaceous carcinomas: a useful and specific immunomarker for the differential diagnosis of eyelid carcinomas ACTA OPHTHALMOLOGICA, 94 :e325-e330 >DOI >Link

Cox TF, Czanner G. 2016. A practical divergence measure for survival distributions that can be estimated from Kaplan-Meier curves STATISTICS IN MEDICINE, 35 :2406-2421 >DOI >Link

Balaskas K, Tiew S, Czanner G, Tan AL, Ashworth J, Biswas S, Aslam T. 2016. The Novel Evidenced Assessment of Tortuosity system: interobserver reliability and agreement with clinical assessment ACTA OPHTHALMOLOGICA, 94 :E421-E426 >DOI >Link

Bunce C, Quartilho A, Freemantle N, Dore CJ. 2016. Ophthalmic statistics note 8: missing data-exploring the unknown BRITISH JOURNAL OF OPHTHALMOLOGY, 100 :291-294 >DOI >Link

MacCormick IJC, Czanner G, Faragher B. 2015. Developing retinal biomarkers of neurological disease: an analytical perspective BIOMARKERS IN MEDICINE, 9 :691-701 >DOI >Link

Boonarpha N, Zheng Y, Stangos AN, Lu H, Raj A, Czanner G, Harding SP, Nair-Sahni J. 2015. Standardization of choroidal thickness measurements using enhanced depth imaging optical coherence tomography INTERNATIONAL JOURNAL OF OPHTHALMOLOGY, 8 :484-491 >DOI >Link

Czanner G, Sarma SV, Ba D, Eden UT, Wu W, Eskandar E, Lim HH, Temereanca S, Suzuki WA, Brown EN. 2015. Measuring the signal-to-noise ratio of a neuron PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112 :7141-7146 >DOI >Link

Stewart RMK, Sheridan CM, Hiscott PS, Czanner G, Kaye SB. 2015. Human Conjunctival Stem Cells are Predominantly Located in the Medial Canthal and Inferior Forniceal Areas INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 56 :2021-2030 >DOI >Link

Spiteri N, Sidaras G, Czanner G, Batterbury M, Kaye SB. 2015. Assessing the quality of ophthalmic anesthesia JOURNAL OF CLINICAL ANESTHESIA, 27 :285-289 >DOI >Link

MacCormick IJC, Czanner G, Faragher B. 2015. Developing retinal biomarkers of neurological disease: an analytical perspective (vol 9, pg 691, 2015) BIOMARKERS IN MEDICINE, 9 :937-937 >DOI >Link

Cumberland PM, Czanner G, Bunce C, Dore CJ, Freemantle N, Garcia-Finana M. 2014. Ophthalmic statistics note: the perils of dichotomising continuous variables BRITISH JOURNAL OF OPHTHALMOLOGY, 98 :841-843 >DOI >Link

Green J, Czanner G, Reeves G, Watson J, Wise L, Roddam A, Beral V. 2012. Menopausal hormone therapy and risk of gastrointestinal cancer: Nested case-control study within a prospective cohort, and meta-analysis INTERNATIONAL JOURNAL OF CANCER, 130 :2387-2396 >DOI >Link

Sarma SV, Nguyen DP, Czanner G, Wirth S, Wilson MA, Suzuki W, Brown EN. 2011. Computing Confidence Intervals for Point Process Models NEURAL COMPUTATION, 23 :2731-2745 >DOI >Link

Green J, Czanner G, Reeves G, Watson J, Wise L, Beral V. 2010. Oral bisphosphonates and risk of cancer of oesophagus, stomach, and colorectum: case-control analysis within a UK primary care cohort BMJ-BRITISH MEDICAL JOURNAL, 341 >DOI >Link

Green J, Czanner G, Reeves G, Watson J, Wise L, Beral V. 2010. Oral bisphosphonates and risk of cancer of oesophagus, stomach, and colorectum: Case-control analysis within a UK primary care cohort BMJ (Online), 341 :545 >DOI

Czanner G, Eden UT, Wirth S, Yanike M, Suzuki WA, Brown EN. 2008. Analysis of between-trial and within-trial neural spiking dynamics JOURNAL OF NEUROPHYSIOLOGY, 99 :2672-2693 >DOI >Link

Krimer LS, Zaitsev AV, Czanner G, Kroner S, Gonzalez-Burgos G, Povysheva NV, Iyengar S, Barrionuevo G, Lewis DA. 2005. Cluster analysis-based physiological classification and morphological properties of inhibitory neurons in layers 2-3 of monkey dorsolateral prefrontal cortex JOURNAL OF NEUROPHYSIOLOGY, 94 :3009-3022 >DOI >Link

Czanner G, Grun S, Iyengar S. 2005. Theory of the snowflake plot and its relations to higher-order analysis methods NEURAL COMPUTATION, 17 :1456-1479 >DOI >Link

Conference publication

Lourenco E, Pratt H, Hamill K, Czanner G, Zheng Y, McCormick A. 2018. Application of SPF moisturizers is inferior to sunscreens in terms of percentage coverage of facial and eyelid area BRITISH JOURNAL OF DERMATOLOGY, 98th Annual Meeting of the British-Association-of-Dermatologists (BAD) 179 :47-47 >Link

Hampden-Martin A, Burgess PIB, Stylianides AS, Czanner GC. 2018. Characterising Diabetic Maculopathy in Patients Receiving Intervention for Hypertension EUROPEAN JOURNAL OF OPHTHALMOLOGY, 28 :20-21 >Link

Czanner G, MacCormick IJ, Zheng Y, Czanner S, Zhao Y, Diggle P, Harding SP. 2017. Spatial distribution modelling of retinal lesions with application to retinal capillary non-perfusion in malarial retinopathy. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO) 58 >Link

MacCormick IJ, Seydel K, Potchen M, Kampondeni S, Heyderman R, Molyneux M, Beare NV, Mallewa M, Czanner G, Taylor T, Harding SP. 2017. Focal breakdown of the blood retinal barrier is associated with fatal brain swelling in paediatric cerebral malaria INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO) 58 >Link

Knox PC, Vazquez NP, Harding SP, Heimann H, Czanner G. 2017. Diagnostic performance of the handheld Radial Shape Discrimination test for detecting recent onset neovascular age-related macular degeneration INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO) 58 >Link

Hughes DM, Bonnett LJ, Czanner G, Komarek A, Marson A, Garcia-Finana M. 2017. EARLY IDENTIFICATION OF PATIENTS WITH DRUG-RESISTANT EPILEPSY EPILEPSIA, 32nd International Epilepsy Congress 58 :S199-S199 >Link

Hassanin K, Pratt H, Zheng Y, Czanner G, Hamill K, McCormick A. 2017. Ultraviolet imaging reveals that areas on the face that are prone to skin cancer are disproportionately missed during sunscreen application BRITISH JOURNAL OF DERMATOLOGY, 97th Annual Meeting of the British-Association-of-Dermatologists 177 :13-14 >Link

Raj A, Czanner G, Sahni J, Campa C, Hagan R, Harding SP. 2016. OSCILLATORY POTENTIAL: A MORE SENSITIVE MARKER FOR DIABETIC MACULOPATHY PROGRESSION? EUROPEAN JOURNAL OF OPHTHALMOLOGY, 26 :E91-E91 >Link

Hassan N, Garcia-Finana M, Czanner G, Jorgensen A. 2015. tSNR as Feature Selection Technique in SNP Data Analysis HUMAN HEREDITY, 44th European Mathematical Genetics Meeting (EMGM) 80 :112-112 >Link

Boonarpha N, Zheng Y, Czanner G, Harding SP, Sahni J. 2015. Impact of hypertension on choroidal thickness in central serous chorioretinopathy INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO) 56 >Link

Czanner G, Gutu T, Harding SP, Holland M, Grierson I, Bennett K, Wuerger S, Sahni J. 2015. Safety and acceptability of an organic light emitting diode (OLED) sleep mask for the treatment of retinal diseases: INSIGHT Study INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO) 56 >Link

Bennett K, Wuerger S, Lowers V, Sahni J, Czanner G, Gutu T, Grierson I, Holland M, Harding S. 2015. A Mixed-Method Analysis Assessing the Effects of Wearing organic light emitting diode (OLED) sleep mask on Sleep and Psychological Wellbeing PERCEPTION, 44 :335-336 >Link

Kaye S, Spiteri N, Czanner G, Batterbury M, Sidaris G. 2014. Quality of ophthalmic anaesthesia and surgical outcome INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 55 >Link

Boonarpha N, Czanner G, Raj A, Zheng Y, Geiser M, Riva C, Sahni J, Harding S. 2013. Improving the Analysis of Choroidal Laser Doppler Flowmetry Measurements; Application in Patients with Retinal Diseases INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 54 >Link

Raj A, Sahni JN, Campa C, Czanner G, Hagan R, Harding SP. 2013. MACULAR FUNCTION: BETTER THAN VISUAL ACUITY FOR ASSESSING DIABETIC MACULOPATHY? EUROPEAN JOURNAL OF OPHTHALMOLOGY, 23 :459-460 >Link

Petrasova A, Czanner G, Happa J, Czanner S, Wolke D, Chalmers A. 2010. Assessing a virtual baby feeding training system Proceedings of AFRIGRAPH 2010: 7th International Conference on Computer Graphics, Virtual Reality, Visualisation and Interaction in Africa, :37-44 >DOI

Kwon JH, Chalmers A, Czanner S, Czanner G, Powell J. 2009. A study of visual perception: Social anxiety and virtual realism Proceedings - SCCG 2009: 25th Spring Conference on Computer Graphics, :167-172 >DOI

Hulusić V, Czanner G, Debattista K, Sikudova E, Dubla P, Chalmers A. 2009. Investigation of the beat rate effect on frame rate for animated content Proceedings - SCCG 2009: 25th Spring Conference on Computer Graphics, :151-159 >DOI

Czanner G, Sarma SV, Eden UT, Brown EN. 2008. A signal-to-noise ratio estimator for generalized linear model systems Ao SI, Gelman L, Hukins DWL, Hunter A, Korsunsky AM. WORLD CONGRESS ON ENGINEERING 2008, VOLS I-II, World Congress on Engineering 2008 :1063-+ >Link

Hume KI, Barrett H, Ip A, McDonagh T, Davies WJ, Adams MD, Bruce NS, Cain R, Jennings P, Czanner G, Carlyle A, Cusack P, Plack C. 2008. Physiological responses and subjective estimates of sounds: Initial results of pilot study Proceedings of the Institute of Acoustics, 30 :576-582

Czanner G, Dreyer AA, Eden UT, Wirth S, Lim HH, Suzuki WA, Brown EN. 2007. Dynamic models of neural spiking activity PROCEEDINGS OF THE 46TH IEEE CONFERENCE ON DECISION AND CONTROL, VOLS 1-14, 46th IEEE Conference on Decision and Control :4173-+ >Link

Czanner G, Dreyer AA, Eden UT, Wirth S, Lim HH, Suzuki WA, Brown EN. 2007. Dynamic models of neural spiking activity Proceedings of the IEEE Conference on Decision and Control, :5812-5817 >DOI

Engagement & Impact

Other Professional Activity:

Research Projects https://scholar.google.co.uk/citations?user=YfYcTBMAAAAJ&hl=en

Teaching qualification:

Fellow of Higher Education Academy