Liverpool Skylilne

Pharmacy and Biomolecular Sciences

Prof Mark Wainwright

Prof Mark Wainwright

Telephone: 0151 231 2039

ORCID

Biography

Medicinal organic chemist. Worked in design, synthesis and applications of photosensitisers since 1987. Particular interest in the application to infection control (photoantimicrobials). Book "Photosensitisers in Biomedicine" (Wiley) published in 2009. Photosensitiser design spin-out Pharmalucia, 2008-2013.

Academic appointments

Professor of Chemotherapy, Pharmacy & Biomol.Sic., Liverpool John Moores University, 2005 - present

Publications

Journal article

Alvarenga LH, Gomes AC, Carribeiro P, Godoy-Miranda B, Noschese G, Simões Ribeiro M, Kato IT, Bussadori SK, Pavani C, Geraldo YGE, Silva DDFTD, Horliana ACRT, Wainwright M, Prates RA. 2019. Parameters for antimicrobial photodynamic therapy on periodontal pocket—Randomized clinical trial Photodiagnosis and Photodynamic Therapy, 27 :132-136 DOI Author Url Publisher Url Public Url

Sabino CP, Wainwright M, Dos Anjos C, Sellera FP, Baptista MS, Lincopan N, Ribeiro MS. 2019. Inactivation Kinetics and Lethal Dose Analysis of Antimicrobial Blue Light and Photodynamic Therapy. Photodiagnosis and Photodynamic Therapy, DOI Author Url Publisher Url Public Url

Okoh OA, Critchley ME, Bisby RH, Lawrence CL, Wainwright M, Smith RB. 2019. Synthesis and photophysical properties of meso-aminophenyl-substituted heptamethine dyes as potential leads to new contrast agents Coloration Technology, 135 :305-311 DOI Publisher Url Public Url

Portapilla GB, Pereira LM, Bronzon Da Costa CM, Providello MV, Sampaio Oliveira PA, Goulart A, Ferreira Anchieta N, Wainwright M, Leite Braga GÚ, De Albuquerque S. 2019. Phenothiazinium Dyes Are Active against Trypanosoma cruzi In Vitro BioMed Research International, 2019 DOI Author Url Publisher Url Public Url

Alberton Nuernberg MA, Janjacomo Miessi DM, Ivanaga CA, Bocalon Olivo M, Ervolino E, Gouveia Garcia V, Wainwright M, Theodoro LH. 2019. Influence of antimicrobial photodynamic therapy as an adjunctive to scaling and root planing on alveolar bone loss: A systematic review and meta-analysis of animal studies Photodiagnosis and Photodynamic Therapy, 25 :354-363 DOI Author Url Publisher Url Public Url

Rodrigues GB, Brancini GTP, Pinto MR, Primo FL, Wainwright M, Tedesco AC, Braga GÚL. 2019. Photodynamic inactivation of Candida albicans and Candida tropicalis with aluminum phthalocyanine chloride nanoemulsion Fungal Biology, DOI

Paziani MH, Tonani L, de Menezes HD, Bachmann L, Wainwright M, Leite Braga GÚ, von Zeska Kress MR. 2018. Antimicrobial Photodynamic Therapy with Phenothiazinium Photosensitizers in non-vertebrate model Galleria mellonella infected with Fusarium keratoplasticum and Fusarium moniliforme. Photodiagnosis and Photodynamic Therapy, 25 :197-203 DOI Author Url Publisher Url Public Url

Longo M, Gouveia Garcia V, Ervolino E, Ferro Alves ML, Duque C, Wainwright M, Theodoro LH. 2018. Multiple aPDT sessions on periodontitis in rats treated with chemotherapy: Histomorphometrical, Immunohistochemical, Imunological and Microbiological Analyses. Photodiagnosis and Photodynamic Therapy, DOI Author Url Publisher Url Public Url

Bacellar IOL, Baptista MS, Junqueira HC, Wainwright M, Thalmann F, Marques CM, Schroder AP. 2018. Permeability of DOPC bilayers under photoinduced oxidation: Sensitivity to photosensitizer Biochimica et Biophysica Acta - Biomembranes, 1860 :2366-2373 DOI Author Url Publisher Url Public Url

Wainwright M. 2018. Photoantimicrobials and PACT: what's in an abbreviation? Photochemical & Photobiological Sciences, DOI Author Url Publisher Url Public Url

Bacellar IOL, Oliveira MC, Dantas LS, Costa EB, Junqueira HC, Martins WK, Durantini AM, Cosa G, Di Mascio P, Wainwright M, Miotto R, Cordeiro RM, Miyamoto S, Baptista MS. 2018. Photosensitized Membrane Permeabilization Requires Contact-Dependent Reactions between Photosensitizer and Lipids Journal of the American Chemical Society, 140 :9606-9615 DOI Author Url Publisher Url Public Url

Wainwright M. 2018. Synthetic, small-molecule photoantimicrobials - a realistic approach. Photochem Photobiol Sci, DOI Author Url

Wainwright M, Stockburn WJ, Lawrence CL, Stevens HJ, Jones AE, Smith RB. 2018. Photoactive plants: Botany bad boys or horticultural heroes? PHYTOTHERAPY RESEARCH, 32 :561-563 DOI Author Url Public Url

Wainwright M. 2017. The problem with dyes in infection control Dyes and Pigments, 146 :402-407 DOI Public Url

Gonzales JC, Brancini GTP, Rodrigues GB, Silva-Junior GJ, Bachmann L, Wainwright M, Braga GÚL. 2017. Photodynamic inactivation of conidia of the fungus Colletotrichum abscissum on Citrus sinensis plants with methylene blue under solar radiation Journal of Photochemistry and Photobiology B: Biology, 176 :54-61 DOI Author Url Public Url

Tonani L, Morosini NS, de Menezes HD, Bonifácio da Silva MEN, Wainwright M, Braga GÚL, von Zeska Kress MR. 2017. In vitro susceptibilities of Neoscytalidium spp. sequence types to antifungal agents and antimicrobial photodynamic treatment with phenothiazinium photosensitizers Fungal Biology, DOI Author Url Public Url

Wainwright M, Maisch T, Nonell S, Plaetzer K, Almeida A, Tegos GP, Hamblin MR. 2017. Photoantimicrobials—are we afraid of the light? The Lancet Infectious Diseases, 17 :e49-e55 DOI Author Url Public Url

Wainwright M. 2017. Dyes, flies, and sunny skies: photodynamic therapy and neglected tropical diseases Coloration Technology, 133 :3-14 DOI Public Url

Wainwright M, McLean A. 2017. Rational design of phenothiazinium derivatives and photoantimicrobial drug discovery Dyes and Pigments, 136 :590-600 DOI Public Url

de Menezes HD, Tonani L, Bachmann L, Wainwright M, Braga G, von Zeska Kress MR. 2016. Photodynamic treatment with phenothiazinium photosensitizers kills both ungerminated and germinated microconidia of the pathogenic fungi Fusarium oxysporum, Fusarium moniliforme and Fusarium solani Journal of Photochemistry and Photobiology B: Biology, 164 :1-12 DOI Author Url Public Url

Brancini GTP, Rodrigues GB, Rambaldi MDSL, Izumi C, Yatsuda AP, Wainwright M, Rosa JC, Braga G. 2016. The effects of photodynamic treatment with new methylene blue N on the: Candida albicans proteome Photochemical and Photobiological Sciences, 15 :1503-1513 DOI Author Url Public Url

Fracarolli L, Rodrigues GB, Pereira AC, Massola Júnior NS, Silva-Junior GJ, Bachmann L, Wainwright M, Bastos JK, Braga GUL. 2016. Inactivation of plant-pathogenic fungus Colletotrichum acutatum with natural plant-produced photosensitizers under solar radiation Journal of Photochemistry and Photobiology B: Biology, 162 :402-411 DOI Author Url Public Url

Wainwright M. 2016. Laser-guided magic bullets-A non-antibiotic answer to O'Neill Photodiagnosis and Photodynamic Therapy, 13 :A1-A2 DOI Author Url Public Url

Spagnul C, Greenman J, Wainwright M, Kamil Z, Boyle RW. 2016. Synthesis, characterization and biological evaluation of a new photoactive hydrogel against Gram-positive and Gram-negative bacteria JOURNAL OF MATERIALS CHEMISTRY B, 4 :1499-1509 DOI Author Url Public Url

Wainwright M, Antczak J, Baca M, Loughran C, Meegan K. 2015. Phenothiazinium photoantimicrobials with basic side chains Journal of Photochemistry and Photobiology B: Biology, 150 :38-43 DOI Author Url Public Url

Tardivo JP, Wainwright M, Baptista M. 2015. Small scale trial of photodynamic treatment of onychomycosis in São Paulo Journal of Photochemistry and Photobiology B: Biology, 150 :66-68 DOI Author Url Public Url

Bacellar IOL, Pavani C, Itri R, Baptista MS, Sales EM, Wainwright M. 2014. Membrane damage efficiency of phenothiazinium photosensitizers Photochemistry and Photobiology, 90 :801-813 DOI

de Menezes HD, Rodrigues GB, Teixeira SDP, Massola NS, Bachmann L, Wainwright M, Braga GUL. 2014. In vitro photodynamic inactivation of plant-pathogenic fungi Colletotrichum acutatum and Colletotrichum gloeosporioides with novel phenothiazinium photosensitizers Applied and Environmental Microbiology, 80 :1623-1632 DOI Author Url

De Menezes HD, Pereira AC, Brancini GTP, De Leão HC, Massola Júnior NS, Bachmann L, Wainwright M, Bastos JK, Braga GUL. 2014. Furocoumarins and coumarins photoinactivate Colletotrichum acutatum and Aspergillus nidulans fungi under solar radiation Journal of Photochemistry and Photobiology B: Biology, 131 :74-83 DOI Author Url

Wainwright M. 2014. In defence of 'dye therapy' International Journal of Antimicrobial Agents, 44 :26-29 DOI Author Url

Rodrigues GB, Dias-Baruffi M, Holman N, Wainwright M, Braga GUL. 2013. In vitro photodynamic inactivation of Candida species and mouse fibroblasts with phenothiazinium photosensitisers and red light Photodiagnosis and Photodynamic Therapy, 10 :141-149 DOI

Wainwright M, Wainwright M. 2013. Photobactericides - a local option against MDR bacteria Antibiotics, 2 :182-190

Wainwright M, Amaral L. 2013. Photobactericides - A local option against multi-drug resistant bacteria Antibiotics, 2 :182-190 DOI

Wainwright M. 2013. Missed chance? Chemistry and Industry (London), 77 :36-39 DOI Author Url

Rodrigues GB, Ferreira LKS, Wainwright M, Braga GUL. 2012. Susceptibilities of the dermatophytes Trichophyton mentagrophytes and T. rubrum microconidia to photodynamic antimicrobial chemotherapy with novel phenothiazinium photosensitizers and red light Journal of Photochemistry and Photobiology B: Biology, 116 :89-94 DOI Author Url

Wainwright M, Smalley H, Flint C. 2011. The use of photosensitisers in acne treatment. J Photochem Photobiol B, 105 :1-5 DOI Author Url

Wainwright M, Meegan K, Loughran C. 2011. Phenothiazinium photosensitisers IX. Tetra- and pentacyclic derivatives as photoantimicrobial agents DYES AND PIGMENTS, 91 :1-5 DOI Author Url

Hope-Roberts M, Horobin RW, Wainwright M. 2011. Identifying apoptotic cells with the 3-hydroxyflavone derivative F2N12S, a ratiometric fluorescent small molecule probe selective for plasma membranes: a possible general mechanism for selective uptake into apoptotic cells BIOTECHNIC & HISTOCHEMISTRY, 86 :255-261 DOI Author Url

Hope-Roberts M, Wainwright M, Horobin RW. 2011. Real-time imaging of bacteria in living mice using a fluorescent dye BIOTECHNIC & HISTOCHEMISTRY, 86 :104-107 DOI Author Url

Wainwright M, Kristiansen JE. 2011. On the 75th anniversary of Prontosil DYES AND PIGMENTS, 88 :231-234 DOI Author Url

Baptista MS, Wainwright M. 2011. Photodynamic antimicrobial chemotherapy (PACT) for the treatment of malaria, leishmaniasis and trypanosomiasis BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 44 :1-10 DOI Author Url

Wainwright M, Brandt SD, Smith A, Styles A, Meegan K, Loughran C. 2010. Phenothiazinium photosensitisers VII: novel substituted asymmetric N-benzylphenothiaziniums as photoantimicrobial agents. J Photochem Photobiol B, 99 :74-77 DOI Author Url

Wainwright M. 2010. Therapeutic applications of near-infrared dyes COLORATION TECHNOLOGY, 126 :115-126 DOI Author Url

Wainwright M, Meegan K, Loughran C, Giddens RM. 2009. Phenothiazinium photosensitisers, Part VI: Photobactericidal asymmetric derivatives DYES AND PIGMENTS, 82 :387-391 DOI Author Url

Jarvis R, Niu X, De Mello AJ, Wainwright M, Wootton RCR. 2009. A microfluidic flow system for activity screening of photo-dynamic therapy agents Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, :603-605

Brandt SD, Martins CPB, Freeman S, Dempster N, Wainwright M, Riby PG, Alder JF. 2008. N,N-Dimethyltryptamine and dichloromethane: rearrangement of quaternary ammonium salt product during GC-EI and CI-MS-MS analysis. J Pharm Biomed Anal, 47 :207-212 DOI Author Url

Hope-Roberts M, Wainwright M, Horobin RW. 2008. A nitrobenzofuran-conjugated phosphatidycholine (C-12-NBD-PC) as a stain for, membrane lamellae for both microscopic imaging and spectrofluorimetry BIOTECHNIC & HISTOCHEMISTRY, 83 :25-28 DOI Author Url

Wainwright M. 2008. Dyes in the development of drugs and pharmaceuticals DYES AND PIGMENTS, 76 :582-589 DOI Author Url

Zainoor NM, Wainwright M, Dyas AM, Rostron C, Brandt S. 2008. An evaluation of the chemotaxonomy of Lignosus rhinocerus JOURNAL OF PHARMACY AND PHARMACOLOGY, 60 :A4-A5 Author Url

Wainwright M, Styles A, Smith A. 2008. Novel phenothiaziniums as putative photo-antiviral agents JOURNAL OF PHARMACY AND PHARMACOLOGY, 60 :A35-A35 Author Url

Wainwright M, Mohr H, Walker WH. 2007. Phenothiazinium derivatives for pathogen inactivation in blood products. J Photochem Photobiol B, 86 :45-58 DOI Author Url

Wainwright M. 2007. Phenothiazinium photosensitisers: V. Photobactericidal activities of chromophore-methylated phenothiazinium salts DYES AND PIGMENTS, 73 :7-12 DOI Author Url

Zainoor NM, Wainwright M, Rostron C, Brandt S. 2007. Distribution of ergosterol in different parts of Lignosus rhinocerus JOURNAL OF PHARMACY AND PHARMACOLOGY, 59 :A59-A60 Author Url

Wainwright M, Byrne MN, Gattrell MA. 2006. Phenothiazinium-based photobactericidal materials. J Photochem Photobiol B, 84 :227-230 DOI Author Url

Wainwright M, Amaral L. 2005. Review: The phenothiazinium chromophore and the evolution of antimalarial drugs TROPICAL MEDICINE & INTERNATIONAL HEALTH, 10 :501-511 DOI Author Url

Wainwright M. 2004. Photoantimicrobials - a PACT against resistance and infection DRUGS OF THE FUTURE, 29 :85-93 DOI Author Url

Phoenix DA, Sayed Z, Hussain S, Harris F, Wainwright M. 2003. The phototoxicity of phenothiazinium derivatives against Escherichia coli and Staphylococcus aureus. FEMS Immunol Med Microbiol, 39 :17-22 DOI Author Url

O'Neill J, Wilson M, Wainwright M. 2003. Comparative antistreptococcal activity of photobactericidal agents JOURNAL OF CHEMOTHERAPY, 15 :329-334 DOI Author Url

Wainwright M, Giddens RM. 2003. Phenothiazinium photosensitisers: choices in synthesis and application DYES AND PIGMENTS, 57 :245-257 DOI Author Url

Wainwright M, Phoenix DA, Nickson PB, Morton G. 2002. The use of new methylene blue in Pseudomonas aeruginosa biofilm destruction BIOFOULING, 18 :247-249 DOI Author Url

Selvasekar CR, Birbeck N, Mcmillan T, Wainwright M, Walker SJ. 2001. Review article: photodynamic therapy and the alimentary tract ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 15 :899-915 DOI Author Url

Wainwright M, Wilson M. 2001. Showing bugs the red light CHEMISTRY & INDUSTRY, :112-115 Author Url

Guinot SGR, Hepworth JD, Wainwright M. 2000. Extended conjugation in di- and tri-arylmethane dyes. Part 5. Vinylogues and ethynologues of Victoria Blue DYES AND PIGMENTS, 47 :129-142 DOI Author Url

Burrow SM, Phoenix DA, Wainwright M, Waring JJ. 2000. Reduced cellular glutathione levels do not affect the cytotoxicity or photocytotoxicity of the photosensitiser Victoria Blue BO BIOLOGICHESKIE MEMBRANY, 17 :282-288 Author Url

Clayton SE, Guinot SGR, Hepworth JD, Wainwright M. 2000. Extended conjugation in di- and tri-arylmethane dyes. Part 4. Steric and electronic effects in analogues of Malachite Green containing a 2H-1-benzopyran unit JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, :263-269 DOI Author Url

Wainwright M, Grice NJ, Pye LEC. 1999. Phenothiazine photosensitizers: part 2. 3,7-Bis(arylamino)phenothiazines DYES AND PIGMENTS, 42 :45-51 DOI Author Url

Guinot SGR, Hepworth JD, Wainwright M. 1999. Extended conjugation in di- and tri-arylmethane dyes. Part 3. The effects of increased planarity in Victoria Blue dyes DYES AND PIGMENTS, 40 :151-156 DOI Author Url

Noodt BB, Rodal GH, Wainwright M, Peng Q, Horobin R, Nesland JM, Berg K. 1998. Apoptosis induction by different pathways with methylene blue derivative and light from mitochondrial sites in V79 cells INTERNATIONAL JOURNAL OF CANCER, 75 :941-948 DOI Author Url

Guinot SGR, Hepworth JD, Wainwright M. 1998. Synthesis of tertiary 1-naphthylamines via the enamine DYES AND PIGMENTS, 36 :387-393 DOI Author Url

Wainwright M, Phoenix DA, Laycock SL, Wareing DR, Wright PA. 1998. Photobactericidal activity of phenothiazinium dyes against methicillin-resistant strains of Staphylococcus aureus. FEMS Microbiol Lett, 160 :177-181 DOI Author Url

Guinot SGR, Hepworth JD, Wainwright M. 1998. The effects of cyclic terminal groups in di- and tri-arylmethane dyes. Part 2. Steric and electronic effects in derivatives of Victoria Blue JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, :297-303 DOI Author Url

Guinot SGR, Hepworth JD, Wainwright M. 1997. A convenient route to 3,6-diaminofluoren-9-ones JOURNAL OF CHEMICAL RESEARCH-S, :183-& DOI Author Url

Griffiths J, Schofield J, Wainwright M, Brown SB. 1997. Some observations on the synthesis of polysubstituted zinc phthalocyanine sensitisers for photodynamic therapy DYES AND PIGMENTS, 33 :65-78 DOI Author Url

Wainwright M. 1996. Non-porphyrin photosensitizers in biomedicine CHEMICAL SOCIETY REVIEWS, 25 :351-+ DOI Author Url

PENG QA, BROWN SB, MOAN J, NESLAND JM, WAINWRIGHT M, GRIFFTHS J, DIXON B, CRUSESAWYER J, VERNON D. 1993. BIODISTRIBUTION OF A METHYLENE-BLUE DERIVATIVE IN TUMOR AND NORMAL-TISSUES OF RATS JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 20 :63-71 DOI Author Url

WAINWRIGHT M, GRIFFITHS J, GUTHRIE JT, GATES AP, MURRAY DE. 1992. COPOLYMERS OF N-VINYLCARBAZOLE WITH MONOMERS CONTAINING CARBOXYLIC-ACID GROUPS OR CARBOXYLIC ANHYDRIDE GROUPS .1. JOURNAL OF APPLIED POLYMER SCIENCE, 44 :1179-1186 DOI Author Url

WAINWRIGHT M, GRIFFITHS J, GUTHRIE JT, GATES AP, MURRAY DE. 1992. COPOLYMERS OF N-VINYLCARBAZOLE WITH MONOMERS CONTAINING CARBOXYLIC-ACID GROUPS OR CARBOXYLIC ANHYDRIDE GROUPS .2. PHOTOCONDUCTIVITY AND COMPOSITION JOURNAL OF APPLIED POLYMER SCIENCE, 44 :1187-1193 DOI Author Url

Wainwright M, Shah A, Meegan K, Loughran C, Smith A, Valli N, Dempster N. Phenothiazinium-fluoroquinolone drug conjugates. Int J Antimicrob Agents, 35 :405-409 DOI Author Url

Wainwright M, Stanforth A, Jones R, Loughran C, Meegan K. Photoantimicrobials as a potential local approach to geriatric UTIs. Lett Appl Microbiol, 50 :486-492 DOI Author Url

Wainwright M. 'Safe' photoantimicrobials for skin and soft-tissue infections. Int J Antimicrob Agents, 36 :14-18 DOI Author Url

Wainwright M. Photoantimicrobials--so what's stopping us? Photodiagnosis Photodyn Ther, 6 :167-169 DOI Author Url

Wainwright M. Photodynamic therapy: the development of new photosensitisers. Anticancer Agents Med Chem, 8 :280-291 DOI Author Url

Wainwright M. Natural Product Photoantimicrobials Current Bioactive Compounds, 3 :252-261 DOI

Wainwright M. Acridine-a neglected antibacterial chromophore. J Antimicrob Chemother, 47 :1-13 DOI Author Url

Rice L, Wainwright M, Phoemix DA. Phenothiazine photosensitizers. III. Activity of methylene blue derivatives against pigmented melanoma cell lines. J Chemother, 12 :94-104 DOI Author Url

Wainwright M. Methylene blue derivatives--suitable photoantimicrobials for blood product disinfection? Int J Antimicrob Agents, 16 :381-394 DOI Author Url

Burrow SM, Phoenix DA, Wainwright M, Waring JJ. Reduced cellular glutathione levels do not affect the cytotoxicity or photocytotoxicity of the cationic photosensitiser Victoria Blue BO. Membr Cell Biol, 14 :357-366 Author Url

Wainwright M, Phoenix DA, Burrow SM, Waring J. Cytotoxicity and adjuvant activity of cationic photosensitizers in a multidrug resistant cell line. J Chemother, 11 :61-68 DOI Author Url

Wainwright M, Phoenix DA, Gaskell M, Marshall B. Photobactericidal activity of methylene blue derivatives against vancomycin-resistant Enterococcus spp. J Antimicrob Chemother, 44 :823-825 DOI Author Url

Rice L, Phoenix DA, Wainwright M, Waring JJ. Effect of increasing methylation on the ability of methylene blue to cause diaphorase-catalysed oxidation of NADH. Biochem Soc Trans, 26 :S319 DOI Author Url

Wainwright M. Photoinactivation of viruses. Photochem Photobiol Sci, 3 :406-411 DOI Author Url

Wainwright M. Local treatment of viral disease using photodynamic therapy. Int J Antimicrob Agents, 21 :510-520 DOI Author Url

Wainwright M, Kristiansen JE. Quinoline and cyanine dyes--putative anti-MRSA drugs. Int J Antimicrob Agents, 22 :479-486 DOI Author Url

Wainwright M. The use of dyes in modern biomedicine. Biotech Histochem, 78 :147-155 DOI Author Url

Wainwright M. Orcein, a traditional stain revealed: some introductory remarks. Biotech Histochem, 78 :285-287 DOI Author Url

Wainwright M. Pathogen inactivation in blood products. Curr Med Chem, 9 :127-143 DOI Author Url

Wainwright M. The emerging chemistry of blood product disinfection. Chem Soc Rev, 31 :128-136 DOI Author Url

Wainwright M, Crossley KB. Methylene Blue--a therapeutic dye for all seasons? J Chemother, 14 :431-443 DOI Author Url

Burrow SM, Phoenix DA, Wainwright M, Tobin MJ. Intracellular localisation studies of doxorubicin and Victoria Blue BO in EMT6-S and EMT6-R cells using confocal microscopy. Cytotechnology, 39 :15-25 DOI Author Url

Wainwright M, Phoenix DA, Smillie TE, Wareing DR. Phenothiaziniums as putative photobactericidal agents for red blood cell concentrates. J Chemother, 13 :503-509 DOI Author Url

Wainwright M, Burrow SM, Guinot SG, Phoenix DA, Waring J. Uptake and cell-killing activities of a series of Victoria blue derivatives in a mouse mammary tumour cell line. Cytotechnology, 29 :35-43 DOI Author Url

Wainwright M. Photodynamic antimicrobial chemotherapy (PACT). J Antimicrob Chemother, 42 :13-28 DOI Author Url

Wainwright M, Phoenix DA, Marland J, Wareing DR, Bolton FJ. A comparison of the bactericidal and photobactericidal activities of aminoacridines and bis(aminoacridines). Lett Appl Microbiol, 26 :404-406 DOI Author Url

Wainwright M, Phoenix DA, Marland J, Wareing DR, Bolton FJ. A study of photobactericidal activity in the phenothiazinium series. FEMS Immunol Med Microbiol, 19 :75-80 DOI Author Url

Wainwright M, Phoenix DA, Marland J, Wareing DR, Bolton FJ. In-vitro photobactericidal activity of aminoacridines. J Antimicrob Chemother, 40 :587-589 DOI Author Url

Wainwright M, Phoenix DA, Rice L, Burrow SM, Waring J. Increased cytotoxicity and phototoxicity in the methylene blue series via chromophore methylation. J Photochem Photobiol B, 40 :233-239 DOI Author Url

Burrow SM, Guinot S, Wainwright M, Waring JJ, Phoenix DA. Investigations of a series of novel cationic photosensitisers and their potential use in photodynamic therapy. Biochem Soc Trans, 23 :260S DOI Author Url

Wainwright M. Handbook of biological dyes and stains ? Synthesis and industrial applications. Biotech Histochem, 86 :444-445 DOI

Wainwright M. Dyes, trypanosomiasis and DNA: a historical and critical review. Biotech Histochem, 85 :341-354 DOI Author Url

Wainwright M, Phoenix DA. Photodynamic Therapy - illuminating the problems of disease. The Biologist, 42 :151-153

Wainwright M, Burrow SM, Phoenix DA. Use of cationic photosensitisers in MDR Cytotechnology, 19 :289-291

Wainwright M. The light fantastic: photodisinfection - an achievable aim for the pharmaceutical industry? Chemistry & Industry, :22-24

Wainwright M. The development of phenothiazinium photosensitisers Photodiagnosis and Photodynamic Therapy, 2 :263-272 DOI Author Url

Wainwright M, Crossley KB. Photosensitising agents - circumventing resistance and breaking down biofilms International Biodeterioration and Biodegradation, :119-126

Wainwright M. Photodynamic therapy - from dyestuffs to high-tech clinical practice Review of Progress in Coloration, 34 :95-109

Wainwright M. Azo dyes and the beginning of the antibiotic era The Colourist, :9-9

Wainwright M. A light sabre to combat the Superbug? The Colourist, :4-4

Wainwright M. Dyes in modern medicine: teaching old stains new tricks? Biotechnic & Histochemistry, :145-145

Wainwright M. Acridines - is it time for another look? Antibiotics & Chemotherapy, 5 :6-7

Wainwright M. Photobactericides - "lightening" the antibiotic load? Alliance for the Prudent Use of Antibiotics Newsletter, 19 :1-5

Wainwright M. Are acridines still obsolete? Society for Applied Microbiology Newsletter, :15-16

Wainwright M, Phoenix DA, Smillie TE, Wareing DRA. Photokilling of Yersinia enterocolitica Transfusion Medicine, 11 :48-49

Wainwright M. Pathogen photoinactivation in blood products Transfusion Medicine, :48-48

Wainwright M. Photoantivirals in blood disinfection Trends in Photochemistry and Photobiology, 8 :97-106

Wainwright M. Phenothiazinium dyes - giving bugs the blues? Spanish Journal of Chemotherapy, 13 :127-128

Wainwright M. An Introduction to Medicinal Chemistry Chemistry & Industry,

Wainwright M. Analytical profiles of drug substances and excipients Trends in Analytical Chemistry, 17 :12-13

Wainwright M, Smalley H, Scully O, Lotfipour E. Comparative photodynamic evaluation of new phenothiazinium derivatives against Propionibacterium acnes. Photochem Photobiol, 88 :523-526 DOI Author Url

Wainwright M. Photodynamic medicine and infection control. J Antimicrob Chemother, 67 :787-788 DOI Author Url

Tardivo JP, Wainwright M, Baptista MS. Local clinical phototreatment of herpes infection in São Paulo Photodiagnosis and Photodynamic Therapy, DOI Author Url

Sadek B, Ashoor A, Mansouri AA, Lorke DE, Nurulain SM, Petroianu G, Wainwright M, Oz M. N3,N7-diaminophenothiazinium derivatives as antagonists of α7-nicotinic acetylcholine receptors expressed in Xenopus oocytes Pharmacological Research, DOI Author Url

Rodrigues GB, Dias-Baruffi M, Braga GUL, Holman N, Wainwright M. In vitro photodynamic inactivation of Candida species and mouse fibroblasts with phenothiazinium photosensitisers and red light Photodiagnosis and Photodynamic Therapy, DOI Author Url

Wainwright M, Dai T, Hamblin MR. Antimicrobial photodynamic therapy in the colon: delivering a light punch to the guts? Photochem Photobiol, 87 :754-756 DOI Author Url

Wainwright M, Baptista MS. The application of photosensitisers to tropical pathogens in the blood supply. Photodiagnosis Photodyn Ther, 8 :240-248 DOI Author Url

Wainwright M. Championing photoantimicrobial discovery. Photodiagnosis Photodyn Ther, 8 :288-289 DOI Author Url

Bacellar IOL, Pavani C, Baptista MS, Sales EM, Itri R, Wainwright M. Membrane damage efficiency of phenothiazinium photosensitizers Photochemistry and Photobiology, DOI Author Url

Wainwright M. Tricyclic cationic chromophores as models for new photoantimicrobials Journal of the Brazilian Chemical Society, DOI Author Url Public Url

Wainwright M, O'Kane C, Rawthore S. Phenothiazinium photosensitisers XI. Improved toluidine blue photoantimicrobials. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, DOI Author Url Public Url

Conference publication

Sanin R, Riby P, Wainwright M, Moore S. 2016. The determination of iron and manganese species in drinking water by LC-ICPMS Biennial Atomic Spectroscopy Symposium 2016

Wainwright M, Crossley KB. 2004. Photosensitising agents - circumventing resistance and breaking down biofilms: a review INTERNATIONAL BIODETERIORATION & BIODEGRADATION, IBBS/IBRG Joint Meeting on management and Control of Microorganisms 53 :119-126 DOI Author Url

BURROW SM, GUINOT S, WAINWRIGHT M, WARING JJ, PHOENIX DA. 1995. INVESTIGATIONS OF A SERIES OF NOVEL CATIONIC PHOTOSENSITIZERS AND THEIR POTENTIAL USE IN PHOTODYNAMIC THERAPY BIOCHEMICAL SOCIETY TRANSACTIONS, 653rd Meeting of the Biochemical-Society-of-London 23 :S260-S260 DOI Author Url

Wainwright M. Phenothiazinium dyes - giving bugs the blues? 3rd European Congress of Chemotherapy

Wainwright M, Brown SB, Griffiths J, Bell A, Roberts DJH, Schofield J. Photodynamic properties of a series of aminoacid-substituted zinc phthalocyanines 2nd International Congress on Porphyrins and Phthalocyanines

Wainwright M. The use of dyes in modern biomedicine Biological Stains Commission

Wainwright M. Photoantimicrobials - the way forward European Society for Photobiology Congress

Wainwright M. Photoantimicrobial Chemotherapy (PACT) (invited lecture) Annual Meeting of the American Society for Photobiology

Wainwright M. Photoantimicrobials in infection control CIFARP

Wainwright M, Phoenix DA, Burrow SM. On the use of cationic triarylmethanes to probe photosensitiser action in an MDR cell line 9th International Conference on Chemical Modifiers of Cancer Treatment

Wainwright M, Burrow SM. The use of cationic non-porphyrin photosensitisers against a multi-drug resistant tumour cell line 6th Congress of the European Society for Photobiology

Wainwright M. Increased bactericidal effects of cationic tricyclics following photoactivation 2nd International Symposium on Recent Advances in the Chemistry of Anti-Infective Agents

Wainwright M. The phototoxicity of Victoria blue BO in MDR EMT6 cells is independent of glutathione levels 12th International Congress on Photobiology (ICP ’96)

Wainwright M, Burrow SM, Phoenix DA. The effect of methylation on the photocytotoxicity of phenothiazine dyes 12th International Congress on Photobiology (ICP ’96)

Wainwright M, Phoenix DA. Development of broad spectrum photoactivable antibacterials 135th Ordinary Meeting of the Society for General Microbiology

Wainwright M. Structure-activity relationships in biomedical photosensitisers Colour Science ’98

Wainwright M. Structure-activity relationships in biomedical photosensitisers Colour Science ’98

Wainwright M. Increased bactericidal effects of aminoacridines following photoactivation Colour Science ’98

Wainwright M. Effect of methylation on the toluidine blue series Colour Science ’98

Wainwright M. Photobactericidal activity of phenothiazinium dyes against methicillin-resistant strains of Staphylococcus aureus British Burns Association, 31st Annual Meeting

Wainwright M. Photobactericidal agents - an option against drug-resistant bacteria 21st International Congress of Chemotherapy

Wainwright M, Aubry JM, DeWilde A. Measurement of the quantum yield of singlet oxygen formation from methylene blue derivatives in D2O and CD3OD Third Annual user Meeting of the Paterson Institute for Cancer Research

Wainwright M, Phoenix DA, Waring DRA. Activity of photobactericidal agents against drug resistant bacteria Society for General Microbiology 148th Ordinary Meeting

Wainwright M. Photoantimicrobial agents in blood product disinfection (Pathogen Inactivation Technology) Society for General Microbiology 148th Ordinary Meeting

Wainwright M, Matchett AA, Percival SL. Control of biofilm formation by photoinactivation of surface-bound phenothiaziniums Society for General Microbiology 148th Ordinary Meeting

Wainwright M, Matchett AA, Nickson PB, Percival SL. Control of biofilms by photoinactivation of exogenous phenothiaziniums 5th Biofilm Community Interactions: Chance or Necessity?

Wainwright M, Phoenix DA, Wareing DRA, Smillie TE. Photokilling of Yersinia enterocolitica BBTS/NVB Annual Scientific Meeting

Wainwright M. Pathogen photoinactivation in blood products BBTS/NVB Annual Scientific Meeting

Wainwright M, Brown SB, Griffiths J, Bell A, Roberts DJH, Schofield J. Aminoacid substituted zinc phthalocyanines for PDT Yorkshire Cancer Research Campaign Annual Conference

Wainwright M. Photosensitising agents – circumventing resistance and breaking down biofilms Management and Control of Microorganisms

Wainwright M. Photoantimicrobials from plants (invited lecture) DEFRA Conference

Wainwright M. Chromophore methylation increases the photoantimicrobial efficacy of azure derivatives British Medical Laser Association, Spring meeting

Wainwright M. Dyes can be drugs too (invited lecture) Annual Meeting of the Society of Dyers & Colourists

Wainwright M, Riby P. Photosensitiser production via microwave synthesis 5th International Microwaves in Chemistry Conference

Wainwright M, Riby P, McGill H. Microwave-assisted synthesis of acridine antibacterials 5th International Microwaves in Chemistry Conference

Wainwright M. Photoantimicrobials – the way forward. (Invited lecture) Recent Developments in Wound Management

Riby P, Salmon P, Roberts M, Brandt S, Wainwright M. Trace Metal Analysis in Pharmaceutical Formulations Biennial National Atomic Spectroscopy/Trace Spec Meeting

Shafaei Arvajeh M, Riby P, Sanin R, Moore S, Wainwright M. Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) in the analysis of manganese and iron in discoloured water Biennal National Atomic Spectroscopy Symposium/Trace Spec

Chapters

Wainwright M. 2011. Phenothiazinium salts as antimicrobial photosensitising agents Hamblin MR, Jori G. Photodynamic Inactivation of Microbial Pathogens Royal Society of Chemistry 9781849731447

Wainwright M. Conn's biological stains Horobin RW, Kiernan JA, Conn HJ. Conn's biological stains BIOS Scientific Publ 9781859960998

Wainwright M. Conn's biological stains Horobin RW, Kiernan JA, Conn HJ. Conn's biological stains BIOS Scientific Publ 9781859960998

Wainwright M. Dyes for the medical industry Clark M. Handbook of Textile and Industrial Dyeing: Applications of Dyes 2 Woodhead Publishing Ltd 978-1845696962 DOI

Wainwright M. The development of clinically useful phenothiazine photosensitisers Pandalai SG. Recent Research Developments in Photochemistry and Photobiology 4 :107-119

Wainwright M. Structure-activity relationships in biomedical photosensitisers Griffiths J, Towns AD. Colour Science ‘98. Dye & Pigment Chemistry 2 :275-288 University of Leeds

Wainwright M, Grice N, Marland J, Phoenix DA, Wareing DRA, Bolton FJ. Increased bactericidal effects of aminoacridines following photoactivation Griffiths J, Towns AD. Colour Science ‘98. Dye & Pigment Chemistry 2 :323-326 University of Leeds

Wainwright M, Rice L, Phoenix DA, Waring JJ. Investigation of methylated derivatives of toluidine blue O as a photosensitiser for PDT Colour Science ‘98. Dye & Pigment Chemistry 2 :327-330 University of Leeds

Wainwright M, Hepworth JD. Supplements to the 2nd edition (editor S. Coffey) of Rodd's chemistry of carbon compounds Rodd EH, Ansell MF. Supplements to the 2nd edition (editor S. Coffey) of Rodd's chemistry of carbon compounds :93-257 9780444899323

Wainwright M, Cruse-Sawyer J, Dixon B, Dawson L, Griffiths J. Photodynamic therapy and biomedical lasers Spinelli P, Fante MD, Marchesini R. Photodynamic therapy and biomedical lasers :806-811 Elsevier 9780444814302

Wainwright M. Photodynamic Therapy Encyclopaedia of Color Science and Technology Springer

Wainwright M. Antimicrobial Dyes McDonnell G, Hansen J. Block's Disinfection, Sterilization, and Preservation Lippincott, Williams & Wilkins

Book

Wainwright M. Photosensitisers in Biomedicine Wiley-Blackwell 9780470510605 DOI

Patent

Wainwright M. Compounds and methods relating thereto

Wainwright M. Ring-fused derivatives of 3,7-diamino- phenothiazinium & phenoselenazinium salts for use as antimicrobial agents

Wainwright M. Phenothiazinium derivatives and their use to reduce pathogenic contaminants

Wainwright M. Compounds and methods relating thereto

Engagement & Impact

Research Grants Awarded:

Ondine Biomedical Inc., Development of novel synthesis and purification methods for methylene blue, Grant value (£): 132,000, Duration of research project: 12 months. 2017

Fellowships:

FSDC, Society of Dyers & Colourists. 2014

FRSC, Royal Society of Chemistry. 2010

Editorial boards:

Dyes & Pigments, Editor. 2010

Photodiagnosis and Photodynamic Therapy, Member. 2010

Photochemical and Photobiological Sciences, Associate Editor. 2009

Biotechnic & Histochemistry, Member. 1999

Journal of Photochemistry & Photobiology B, Biology, Member. 1998

Membership of professional bodies:

Member, British Society for Antimicrobial Chemotherapy. 1995

Member, European Society for Photobiology. 1994