Dr Neil Henney

Pharmacy and Biomolecular Sciences

Neil is the leader of the MPharm Pharmacy degree programme in the School of Pharmacy & Biomolecular Sciences. Neil graduated with an MPharm degree, and later a PhD (in pharmacology and electrophysiology, studying bone cell function), from Cardiff University. He began his professional career as a hospital clinical pharmacist, and has practice experience in hospital pharmacy, community pharmacy and in the prison sector as well as extensive experience as a pharmacy educator.

Neil teaches pharmacology and pharmacy practice at all levels of MPharm, and also contributes to a number of modules on postgraduate non-medical prescribing programmes (for pharmacists and for nurses), and undergraduate Biomedical Science and Pharmaceutical Science programmes.

Neil is a member of the Clinical Pharmacy & Therapeutics research group. He supervises postgraduate research students (PhD and MPhil) and postgraduate taught (Masters) students in the fields of pharmacology/physiology and pharmacy practice. Recent successful candidates have undertaken research in ionic mechanisms of disease (adipogenesis in bone), Daphnia as a model for cardiovascular disease, and the optimisation of antibiotic delivery in patients with sepsis.

Neil's research interests are focused on two particular themes:
1) understanding the mechanisms of disease - in particular the contributions made by ion channels to both 'normal' and disturbed physiology - using electrophysiological, pharmacological and evidence synthesis methods. Key interests in this area include studies on bone physiology and pathophysiology, and cardiac dysrhythmias.
2) the optimisation of antibiotic use in patients, through evidence synthesis and mathematical modelling methods (e.g. PBPK and pharmacodynamic modelling).

Degrees

Cardiff University, United Kingdom, PhD
Cardiff University, United Kingdom, MPharm

Academic appointments

Programme Leader, Pharmacy, Pharmacy & Biomolecular Sciences, Liverpool John Moores University, 2020 - present
Senior Lecturer in Pharmacology, Pharmacy & Biomolecular Sciences, Liverpool John Moores University, 2009 - present
Teaching Fellow, Welsh School of Pharmacy, Cardiff University, 2009 - 2009

Postgraduate training

Postgraduate Certificate in Learning and Teaching in Higher Education, United Kingdom, Liverpool John Moores University, 2010 - 2011

Editorial/letter to the editor

Davies J, Cutler S, Henney N. 2022. A day in the life: a novel approach to virtual simulation for undergraduate pharmacy students International Journal of Healthcare Simulation, Volume :A57-A58 DOI

Penson P, Henney N. 2021. Bacterial lipopolysaccharide – stoking the fire of residual risk? Trends in Cardiovascular Medicine, DOI Author Url Publisher Url

Conference publication

Spencer J, Penson PE, Henney N. 2022. P021 | Exploring the association between antihypertensive drug treatment and depression: an observational study British Journal of Clinical Pharmacology, Pharmacology 2022 DOI Author Url

Consterdine S, Penson PE, Henney N. 2022. P011 | An investigation of the association between depression and cardiovascular mortality, and the impact of antidepressants on this relationship British Journal of Clinical Pharmacology, DOI

Penson P, Henney N, Banach M. 2021. Association between ankle-brachial index and cardiovascular mortality in a cohort from the United States of America European Heart Journal, ESC Congress 2021: The Digital Experience DOI Author Url Publisher Url

Hughes L, Henney N, Banach M, Penson P. 2021. Sleep disorders are associated with cardiovascular risk factors in American adults. HEART UK 34th Annual Medical & Scientific Virtual Conference 2021 Author Url

Penson P, Martin SS, Henney N, Banach M. 2020. Comparison of LDL-C calculation by Friedewald and Martin/Hopkins methods in 12,243 adults from the United States of America European Society of Cardiology Congress 2020 DOI Author Url

Bastien M, Downing JD, Evans AR, Henney N. 2017. Identification of new alternatively spliced ghrelin variants in mouse osteoblastic cell line 7F2. 38th World Congress of the International Union of Physiological Sciences (IUPS)conference

Barton G, Henney N, Morecroft C. 2014. A SURVEY OF INTRAVENOUS ANTIBIOTIC ADMINISTRATION PRACTICES IN UK CRITICAL CARE UNITS INTENSIVE CARE MEDICINE, 27th Annual Congress of the European-Society-of-Intensive-Care-Medicine (ESICM) 40 :S261-S261 Author Url

Henney NC, Evans BAJ, Kidd EJ, Wann KT. 2009. TRPV1b is expressed and may assist in pH ‘switching’ of human osteoblasts Calcified Tissue International, 2nd Joint Meeting of the British Society for Matrix Biology and Bone Research Society 85 :175-175

Henney NC, Evans BAJ, Campbell AK, Wann KT. 2007. TRP channels are both present and functional in human osteoblast-like cells JOURNAL OF BONE AND MINERAL RESEARCH, 29th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research 22 :S237-S237 Author Url

Li B, Henney NC, Evans BAJ, Reviriego P, Campbell AK, Wann KT. 2007. BK channels in human osteoblast-like cells - Properties and function JOURNAL OF BONE AND MINERAL RESEARCH, 29th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research 22 :S373-S373 Author Url

Li B, Henney NC, Evans BAJ, Wann KT. 2007. Large conductance potassium channel in human osteoblast cells Proceedings of the British Pharmacological Society, British Pharmacological Society

Li B, Henney NC, Evans BA, Reviriego P, Campbell AK, Wann KT. 2007. BK channels are expressed and functional in human osteoblast-like cells Proceedings of Life Sciences, Life Sciences 2007 :PC162-PC162

Henney NC, Evans BA, Campbell AK, Wann KT. 2007. Make no bones about TRP channels Proc Life Sciences, Life Sciences 2007 :PC231-PC231

Henney N, Li B, Evans BAJ, Hall EJ, Wann KT. 2006. Potassium channel subunits in human osteoblast-like cells JOURNAL OF BONE AND MINERAL RESEARCH, 21 :1169-1169 Author Url

Wann KT, Henney N, Prajerova I, Boolaky UV, Evans BAJ. 2004. Human osteoblast-like cells have high density maxi-K channels JOURNAL OF BONE AND MINERAL RESEARCH, 19 :1051-1051 Author Url

Wann KT, Henney NC, Prajerova I, Boolaky UV, Evans BAJ. 2004. Single channels in human osteoblast-like cells The Journal of Physiology, :555P-555P

Henney NC, Thomas A, Evans BAJ, Wann KT. A role for TRPV1 and K+ channels in the regulation of osteoblast differentiation to adipocytes Calcified Tissue International, 2nd Joint Meeting of the British Society for Matrix Biology and Bone Research Society 85 :174-174

Bastien M, Downing J, Evans A, Henney N. A study of the role of ghrelin and ionic mechanisms in adipogenic differentiation of bone Bone Research Society Annual Meeting 2016 DOI

Journal article

Zahedipour F, Hosseini S, Henney N, Barreto G, Sahebkar A. 2022. Phytochemicals as inhibitors of tumor necrosis factor alpha and neuroinflammatory responses in neurodegenerative diseases Neural Regeneration Research, 17 :1675-1684 DOI Author Url Publisher Url Public Url

Avan R, Sahebnasagh A, Hashemi J, Monajati M, Faramarzi F, Henney NC, Montecucco F, Jamialahmadi T, Sahebkar A. 2021. Update on Statin Treatment in Patients with Neuropsychiatric Disorders Life, 11 DOI Author Url Publisher Url Public Url

Henney N, Banach M, Penson P. 2021. RNA Silencing in the Management of Dyslipidemias Current Atherosclerosis Reports, DOI Author Url Publisher Url Public Url

Afshari AR, Mollazadeh H, Henney NC, Jamialahmad T, Sahebkar A. 2021. Effects of statins on brain tumors: a review Seminars in Cancer Biology, 73 :116-133 DOI Author Url Publisher Url Public Url

Askarizadeh A, Barreto GE, Henney NC, Majeed M, Sahebkar A. 2020. Neuroprotection by curcumin: A review on brain delivery strategies International Journal of Pharmaceutics, 585 DOI Author Url

Ritchie L, Qin S, Penson P, Henney N, Lip G. 2020. Vernakalant hydrochloride for the treatment of atrial fibrillation: An evaluation of its place in clinical practice Future Cardiology, 16 :585-595 DOI Author Url Publisher Url Public Url

Tajbakhsh A, Rezaee M, Barreto GE, Moallem SA, Henney NC, Sahebkar A. 2020. The role of nuclear factors as “Find-Me”/alarmin signals and immunostimulation in defective efferocytosis and related disorders International Immunopharmacology, 80 DOI Author Url

Yaribeygi H, Ashrafizadeh M, Henney NC, Sathyapalan T, Jamialahmadi T, Sahebkar A. 2020. Neuromodulatory effects of anti-diabetes medications: A mechanistic review Pharmacological Research, 152 DOI Author Url

Barton GJ, Morecroft CW, Henney N. 2019. A survey of antibiotic administration practices involving patients with sepsis in UK Critical Care Units International Journal of Clinical Pharmacy, 42 :65-71 DOI Author Url Publisher Url Public Url

Henney NC, Li B, Elford C, Reviriego P, Campbell AK, Wann KT, Evans BAJ. 2009. A large-conductance (BK) potassium channel subtype affects both growth and mineralization of human osteoblasts. Am J Physiol Cell Physiol, 297 :C1397-C1408 DOI Author Url

Chapters

Riahi MM, Behnam B, Henney NC, Jamialahmadi T, Sahebkar A. 2021. Protective Effects of Curcumin in the Reproductive System: Anti-toxic, Semen Cryopreservative, and Contraceptive Actions 1328 :223-242 Springer DOI Author Url Publisher Url

Penson P, Henney N. 2013. Homeostasis Gaskell E, Rostron C. Therapeutics and Human Physiology OUP Oxford 9780199655298 Author Url

Henney N, Penson P. 2013. Communication systems in the body - neural Gaskell E, Rostron C. Therapeutics and Human Physiology OUP Oxford 9780199655298 Author Url

Book review

Henney N. 2019. Raymond Hill, Terry Kenakin and Tom Blackburn (Eds): Pharmacology for Chemists—Drug Discovery in Context Chromatographia, 82 :1111-1111 DOI

Henney NC. 2015. Glenn F. King: Venoms to Drugs: Venom as a Source for the Development of Human Therapeutics Chromatographia, DOI

Henney NC. 2011. Povl Krogsgaard-Larsen, Kristian Strømgaard, and Ulf Madsen (Eds.): Textbook of Drug Design and Discovery Chromatographia, 74 :745-746 DOI

Henney NC. 2011. John C. Foreman, Torben Johansen, and Alasdair J. Gibb (Eds.): Textbook of Receptor Pharmacology 74 :743-744 DOI

Henney NC. 2011. Monzer Fanun (Ed.): Colloids in Drug Delivery Chromatographia, 75 :81-81 DOI

Book

Gaskell EE, Evans A, Henney N, Penson P, Elliott PNC, Burrell H, Airley R, Ford W, Lane E, Allison GL. 2013. Therapeutics and Human Physiology Gaskell EE, Rostron C. OUP Oxford. Oxford, UK 9780199655298 Author Url Publisher Url

Thesis/Dissertation

Henney NC. 2009. The expression and characteristics of ion channels in osteoblasts: putative roles for TRP and K+ channels Wann KT, Campbell AK. Cardiff University

Teaching qualification:

Postgraduate Certificate of Teaching and Learning in Higher Education. 2011

Membership of professional bodies:

Registered pharmacist, General Pharmaceutical Council. 2004

Fellow, Higher Education Academy.

Member, Marine Biological Association of the UK.

Member, Royal Pharmaceutical Society.

External collaboration:

Cardiff University, Dr Bronwen AJ Evans.

Cardiff University, Professor Kenneth T Wann.

Cardiff University, Professor Tony Campbell CBE.

St Helens and Knowsley NHS Trust, Greg Barton MBE.

University of Stirling, Dr Andy Hoyle.

Editorial boards:

The Young Darwinian, Member, Editorial Advisory Board.

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