Image of Dr Sam Shepherd

Dr Sam Shepherd

Sport and Exercise Sciences

Faculty of Science

Dr Sam Shepherd (Reader in Exercise Metabolism & Nutrition) is an academic staff member with teaching duties. Sam’s research aims to develop exercise and/or nutritional strategies to 1) improve cardio-metabolic health and insulin sensitivity in at-risk populations (metabolic syndrome, type I and type II diabetes, aging), and 2) maximise the metabolic adaptations to acute and chronic exercise training. Contributing to achieving these aims is a large body of work that focuses on understanding the molecular regulation of skeletal muscle lipid metabolism. Sam is also an expert in the use of immunofluorescence microscopy and transmission electron microscopy, methods which are integral to previous and ongoing research studies.

Degrees

2012, University of Birmingham, United Kingdom, PhD Exercise Metabolism
2008, University of Aberdeen, United Kingdom, MSc Human Nutrition & Metabolism
2007, University of Birmingham, United Kingdom, BSc Sport & Exercise Sciences

Academic appointments

Reader in Exercise Metabolism & Nutrition, Research Institute for Sport & Exercise Sciences, Liverpool John Moores University, 2022 - present
Lecturer/Senior Lecturer in Sport & Exercise Nutrition, Liverpool John Moores University, 2012 - 2022

Postgraduate training

PGCert Learning & Teaching in HE, United Kingdom, Liverpool John Moores University, 2013 - 2015

Journal article

Barrett JS, Strauss JA, Chow LS, Shepherd SO, Wagenmakers AJM, Wang Y. 2024. GLUT4 localisation with the plasma membrane is unaffected by an increase in plasma free fatty acid availability Lipids in Health and Disease, 23 :1-13 DOI Author Url Publisher Url Public Url

Srisawat K, Stead CA, Hesketh K, Pogson MA, Strauss JA, Cocks MS, Siekmann I, Phillips SM, Lisboa PJ, Shepherd SO, Burniston JG. 2023. People with obesity exhibit losses in muscle proteostasis that are partly improved by exercise training Proteomics, :1-14 DOI Author Url Publisher Url Public Url

Baumert P, Cocks MS, Strauss JA, Shepherd SO, Drust B, Lake MJ, Stewart CE, Erskine RM. 2022. Polygenic Mechanisms Underpinning the Response to Exercise-Induced Muscle Damage in Humans: in vivo and in vitro Evidence Journal of Cellular Physiology, DOI Author Url Publisher Url Public Url

Barrett J, Whytock KL, Strauss JA, Wagenmakers AJM, Shepherd SO. 2022. High intramuscular triglyceride turnover rates and the link to insulin sensitivity: Influence of obesity, type 2 diabetes and physical activity. Applied Physiology, Nutrition, and Metabolism, DOI Author Url Publisher Url Public Url

Hesketh KL, Jones H, Kinnafick F, Shepherd SO, Wagenmakers AJM, Strauss JA, Cocks MS. 2021. Home-Based HIIT and Traditional MICT Prescriptions Improve Cardiorespiratory Fitness to a Similar Extent Within an Exercise Referral Scheme for At-Risk Individuals Frontiers in Physiology, 12 DOI Author Url Publisher Url Public Url

Hesketh KL, Church H, Kinnafick F, Shepherd SO, Wagenmakers AJM, Cocks MS, Strauss JA. 2021. Evidence-based vs. social media based high-intensity interval training protocols: Physiological and perceptual responses. PLoS One, 16 DOI Author Url Publisher Url Public Url

Fell JM, Hearris MA, Ellis DG, Moran JEP, Jevons EFP, Owens DJ, Strauss JA, Cocks MS, Louis JB, Shepherd SO, Morton JP. 2021. Carbohydrate improves exercise capacity but does not affect subcellular lipid droplet morphology, AMPK and p53 signalling in human skeletal muscle The Journal of Physiology, DOI Author Url Publisher Url Public Url

Baumert P, Temple S, Stanley JM, Cocks MS, Strauss JA, Shepherd SO, Drust B, Lake MJ, Stewart CE, Erskine RM. 2021. Neuromuscular fatigue and recovery after strenuous exercise depends on skeletal muscle size and stem cell characteristics. Scientific Reports, 11 DOI Author Url Publisher Url Public Url

Maasar M-F, Turner DC, Gorski PP, Seaborne RA, Strauss JA, Shepherd SO, Cocks M, Pillon NJ, Zierath JR, Hulton AT, Drust B, Sharples AP. 2021. The Comparative Methylome and Transcriptome After Change of Direction Compared to Straight Line Running Exercise in Human Skeletal Muscle. Frontiers in Physiology, 12 :619447-619447 DOI Author Url Publisher Url Public Url

Morris A, Murphy RC, Hopkins ND, Low DA, Healy G, Edwardson C, Collins B, Timpson H, Shepherd SO, Cochrane MA, Gavin D, Graves LEF. 2021. Sit Less and Move More - A multi-component intervention with and without height-adjustable workstations in contact centre call agents: a pilot randomised controlled trial Journal of Occupational and Environmental Medicine, 63 :44-56 DOI Author Url Publisher Url Public Url

Hearris MA, Owens DJ, Strauss JA, Shepherd SO, Sharples AP, Morton JP, Louis JB. 2020. Graded reductions in pre-exercise glycogen concentration do not augment exercise-induced nuclear AMPK and PGC-1α protein content in human muscle. Experimental Physiology, 105 :1882-1894 DOI Author Url Publisher Url Public Url

Malik Z, Bowden Davies K, Hall E, Barrett J, Pullinger S, Erskine RM, Shepherd SO, Iqbal Z, Edwards BJ, Burniston JG. 2020. Diurnal differences in human muscle isometric force and rate of force development in vivo are associated with differential phosphorylation of sarcomeric M-band proteins. Proteomes, 8 DOI Author Url Publisher Url Public Url

Whytock KL, Shepherd SO, Cocks MS, Wagenmakers AJM, Strauss JA. 2020. Young, healthy males and females present cardiometabolic protection against the detrimental effects of a 7-day high-fat high-calorie diet European Journal of Nutrition, DOI Author Url Publisher Url Public Url

Nolan A, Brett R, Strauss JA, Stewart CE, Shepherd SO. 2020. Short-term, but not acute, intake of New Zealand blackcurrant extract improves insulin sensitivity and free-living postprandial glucose excursions in individuals with overweight or obesity European Journal of Nutrition, DOI Author Url Publisher Url Public Url

Strauss JA, Shepherd DA, Macey M, Jevons EFP, Shepherd SO. 2020. Divergence exists in the subcellular distribution of intramuscular triglyceride in human skeletal muscle dependent on the choice of lipid dye. Histochemistry and Cell Biology, DOI Author Url Publisher Url Public Url

Strauss JA, Ranasinghe C, Cowley E, Schwingshackl L, Shepherd SO, Chaplin M, Garner P. 2020. High-intensity interval training for reducing cardiometabolic syndrome in healthy but sedentary populations Cochrane Database of Systematic Reviews, 2020 DOI Publisher Url

Impey SG, Jevons EFP, Mees G, Cocks MS, Strauss JA, Chester N, Laurie I, Target D, Hodgson A, Shepherd SO, Morton JP. 2020. Glycogen Utilization during Running: Intensity, Sex, and Muscle-specific Responses. Medicine and Science in Sports and Exercise, DOI Author Url Publisher Url Public Url

Jevons EFP, Gejl KD, Strauss JA, Ørtenblad N, Shepherd SO. 2020. Skeletal muscle lipid droplets are resynthesized before being coated with perilipin proteins following prolonged exercise in elite male triathletes. American Journal of Physiology: Endocrinology and Metabolism, 318 :E357-E370 DOI Author Url Publisher Url Public Url

Whytock KL, Parry SA, Turner MC, Woods RM, James LJ, Ferguson RA, Ståhlman M, Borén J, Strauss JA, Cocks MS, Wagenmakers AJM, Hulston CJ, Shepherd SO. 2020. A 7-day high-fat, high-calorie diet induces fibre-specific increases in intramuscular triglyceride and perilipin protein expression in human skeletal muscle Journal of Physiology, 598 :1151-1167 DOI Author Url Publisher Url Public Url

Roerink SHPP, Cocks MS, Wagenmakers MAEM, Rodighiero RP, Strauss JA, Shepherd SO, Plantinga TS, Thijssen DHJ, Hopman MTE, Pereira AM, Smit JW, Wagenmakers AJM, Netea-Maier RT, Hermus ARMM. 2019. Decreased Aerobic Exercise Capacity After Long-Term Remission From Cushing Syndrome: Exploration of Mechanisms. Journal of Clinical Endocrinology and Metabolism, 105 DOI Author Url Publisher Url Public Url

Srisawat K, Hesketh KL, Cocks MS, Strauss JA, Edwards BJ, Lisboa PJ, Shepherd SO, Burniston JG. 2019. Reliability of Protein Abundance and Synthesis Measurements in Human Skeletal Muscle. Proteomics, 20 DOI Author Url Publisher Url Public Url

Scott SN, Shepherd SO, Strauss JA, Wagenmakers AJM, Cocks MS. 2019. Home-based high-intensity interval training reduces barriers to exercise in people with type 1 diabetes Experimental Physiology, DOI Author Url Publisher Url Public Url

Scott SN, Shepherd SO, Andrews RC, Narendran P, Purewal TS, Kinnafick F, Cuthbertson DJ, Atkinson-Goulding S, Noon T, Wagenmakers AJM, Cocks MS. 2019. A Multidisciplinary Evaluation of a Virtually Supervised Home-Based High-Intensity Interval Training Intervention in People With Type 1 Diabetes. Diabetes Care, DOI Author Url Publisher Url Public Url

Parry SA, Turner MC, Woods RM, James LJ, Ferguson RA, Cocks M, Whytock KL, Strauss JA, Shepherd SO, Wagenmakers AJM, van Hall G, Hulston CJ. 2019. High-fat overfeeding impairs peripheral glucose metabolism and muscle microvascular eNOS Ser1177 phosphorylation. Journal of Clinical Endocrinology and Metabolism, 105 DOI Author Url Publisher Url Public Url

Hammond KM, Sale C, Fraser W, Tang J, Shepherd SO, Strauss JA, Close GL, Cocks MS, Louis J, Pugh JN, Stewart CE, Sharples AP, Morton JP. 2019. Post-exercise carbohydrate and energy availability induce independent effects on skeletal muscle cell signalling and bone turnover: implications for training adaptation The Journal of Physiology, 597 :4779-4796 DOI Author Url Publisher Url Public Url

Scott SN, Shepherd SO, Hopkins ND, Dawson EA, Strauss JA, Wright DJ, Cooper RG, Kumar P, Wagenmakers AJM, Cocks MS. 2019. Home-HIT improves muscle capillarisation and eNOS/NAD(P)Hoxidase protein ratio in obese individuals with elevated cardiovascular disease risk. Journal of Physiology, DOI Author Url Publisher Url Public Url

Routledge HE, Bradley WJ, Shepherd SO, Cocks MS, Erskine RM, Close GL, Morton JP. 2019. Ultrasound Does Not Detect Acute Changes in Glycogen in Vastus Lateralis of Man. Medicine and Science in Sports and Exercise, DOI Author Url Publisher Url Public Url

Hesketh K, Shepherd SO, Strauss JA, Low DA, Cooper RG, Wagenmakers AJM, Cocks MS. 2019. Passive Heat Therapy in Sedentary Humans Increases Skeletal Muscle Capillarisation and eNOS Content but Not Mitochondrial Density or GLUT4 Content. AJP - Heart and Circulatory Physiology, 317 :H114-H123 DOI Author Url Publisher Url Public Url

Hearris MA, Hammond KM, Seaborne RA, Stocks B, Shepherd SO, Philp A, Sharples AP, Morton JP, Louis JB. 2019. Graded reductions in pre-exercise muscle glycogen impair exercise capacity but do not augment cell skeletal muscle signalling: implication for CHO periodisation Journal of Applied Physiology, DOI Author Url Publisher Url Public Url

Morris AS, Murphy RC, Shepherd SO, Healy GN, Edwardson CL, Graves LEF. 2019. A multi-component intervention to sit less and move more in a contact centre setting: A feasibility study BMC Public Health, 19 DOI Author Url Publisher Url Public Url

Scott SN, Cocks MS, Andrews RC, Narendran P, Purewal TS, Cuthbertson DJ, Wagenmakers AJM, Shepherd SO. 2019. Hit Improves Aerobic Capacity Without a Detrimental Decline in Blood Glucose in People with Type 1 Diabetes. Journal of Clinical Endocrinology and Metabolism, 104 :604-612 DOI Author Url Publisher Url Public Url

Seaborne RA, Strauss JA, Cocks MS, Shepherd SO, O'Brien TD, van Someren KA, Bell PG, Murgatroyd C, Morton JP, Stewart CE, Mein CA, Sharples AP. 2018. Methylome of human skeletal muscle after acute & chronic resistance exercise training, detraining & retraining Scientific Data, 5 DOI Author Url Publisher Url Public Url

Scott SN, Cocks MS, Andrews RC, Narendran P, Purewal TS, Cuthbertson DJ, Wagenmakers AJM, Shepherd SO. 2018. Fasted High-Intensity Interval and Moderate-Intensity Exercise do not Lead to Detrimental 24-Hour Blood Glucose Profiles. Journal of Clinical Endocrinology & Metabolism, DOI Author Url Publisher Url Public Url

Morris AS, Murphy RC, Shepherd SO, Graves LEF. 2018. Multi-stakeholder perspectives of factors that influence contact centre call agent’s workplace physical activity and sedentary behaviour International Journal of Environmental Research and Public Health, 7 DOI Author Url Publisher Url Public Url

Impey SG, Hammond KM, Naughton R, Langan-Evans C, Shepherd SO, Sharples AP, Cegielski J, Smith K, Jeromson S, Hamilton DL, Close GL, Morton JP. 2018. Whey Protein Augments Leucinemia and Post-Exercise p70S6K1 Activity Compared to a Hydrolysed Collagen Blend When in Recovery From Training With Low Carbohydrate Availability International Journal of Sport Nutrition and Exercise Metabolism, DOI Author Url Publisher Url Public Url

Strauss JA, Willems MET, Shepherd SO. 2018. New Zealand blackcurrant extract enhances fat oxidation during prolonged cycling in endurance-trained females. European Journal of Applied Physiology, DOI Author Url Publisher Url Public Url

Whytock KL, Shepherd SO, Wagenmakers AJM, Strauss JA. 2018. Hormone sensitive lipase preferentially redistributes to perilipin-5 lipid droplets in human skeletal muscle during moderate-intensity exercise. Journal of Physiology, DOI Author Url Publisher Url Public Url

Kinnafick F-E, Thøgersen-Ntoumani C, Shepherd SO, Wilson OJ, Wagenmakers AJM, Shaw CS. 2018. In It Together: A Qualitative Evaluation of Participant Experiences of a 10-Week, Group-Based, Workplace HIIT Program for Insufficiently Active Adults. Journal of Sport and Exercise Psychology, DOI Author Url Publisher Url Public Url

Seaborne RA, Strauss JA, Cocks MS, Shepherd SO, O'Brien TD, van Someren KA, Bell PG, Murgatroyd C, Morton JP, Stewart CE, Sharples AP. 2018. Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy Scientific Reports, 8 DOI Author Url Publisher Url Public Url

Srisawat K, Shepherd SO, Lisboa PJ, Burniston JG. 2017. A Systematic Review and Meta-Analysis of Proteomics Literature on the Response of Human Skeletal Muscle to Obesity/Type 2 Diabetes Mellitus (T2DM) Versus Exercise Training. Proteomes, 5 DOI Author Url Publisher Url Public Url

Whytock KL, Jevons EFP, Strauss JA, Shepherd SO. 2017. Under the microscope: insights into limb-specific lipid droplet metabolism. J Physiol, DOI Author Url Publisher Url

Allan R, Sharples AP, Close GL, Drust B, Shepherd SO, Dutton J, Morton JP, Gregson W. 2017. Postexercise cold water immersion modulates skeletal muscle PGC-1 alpha mRNA expression in immersed and nonimmersed limbs: evidence of systemic regulation Journal of Applied Physiology, 123 :451-459 DOI Author Url Publisher Url Public Url

Shepherd SO, Cocks MS, Meikle PJ, Mellett NA, Ranasinghe AM, Barker TA, Wagenmakers AJM, Shaw CS. 2017. Lipid droplet remodelling and reduced muscle ceramides following sprint interval and moderate-intensity continuous exercise training in obese males. International Journal of Obesity, DOI Author Url Publisher Url Public Url

Chow LS, Mashek DG, Wang Q, Shepherd SO, Goodpaster BH, Dubé JJ. 2017. Effect of acute physiological free fatty acid elevation in the context of hyperinsulinemia on fiber type-specific IMCL accumulation. Journal of Applied Physiology (1985), 123 :71-78 DOI Author Url Publisher Url Public Url

Bartlett DB, Shepherd SO, Wilson OJ, Adlan AM, Wagenmakers AJM, Shaw CS, Lord JM. 2017. Neutrophil and Monocyte Bactericidal Responses to 10 Weeks of Low-Volume High-Intensity Interval or Moderate-Intensity Continuous Training in Sedentary Adults OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, DOI Author Url Publisher Url Public Url

Shepherd SO, Strauss JA, Wang Q, Dube JJ, Goodpaster B, Mashek DG, Chow LS. 2017. Training alters the distribution of perilipin proteins in muscle following acute free fatty acid exposure. Journal of Physiology, DOI Author Url Publisher Url Public Url

Bradley WJ, Hannon MP, Benford V, Morehen JC, Twist C, Shepherd SO, Cocks MS, Impey SG, Cooper RG, Morton JP, Close GL. 2017. Metabolic demands and replenishment of muscle glycogen after a rugby league match simulation protocol. Journal of Science and Medicine in Sport, DOI Author Url Publisher Url Public Url

Bradley WJ, Morehen JC, Haigh J, Clarke J, Donovan TF, Twist C, Cotton C, Shepherd S, Cocks M, Sharma A, Impey SG, Cooper RG, Maclaren DPM, Morton JP, Close GL. 2016. Muscle glycogen utilisation during Rugby match play: Effects of pre-game carbohydrate Journal of Science and Medicine in Sport, 19 :1033-1038 DOI Author Url Publisher Url

Hammond KM, Impey SG, Currell K, Mitchell N, Shepherd SO, Jeromson S, Hawley JA, Close GL, Hamilton DL, Sharples AP, Morton JP. 2016. Postexercise High-Fat Feeding Supresses p70S6K1 Activity in Human Skeletal Muscle. Medicine and Science in Sports and Exercise, DOI Author Url Publisher Url Public Url

Impey SG, Hammond KM, Shepherd SO, Sharples AP, Stewart CE, Limb M, Smith K, Philp A, Jeromson S, Hamilton DL, Close GL, Morton JP. 2016. Fuel for the work required: a practical approach to amalgamating train-low paradigms for endurance athletes. Physiological Reports, 4 DOI Author Url Publisher Url Public Url

Thøgersen-Ntoumani C, Shepherd SO, Ntoumanis N, Wagenmakers AJM, Shaw CS. 2016. Intrinsic motivation in two exercise interventions: Associations with fitness and body composition. Health Psychology, 35 :195-198 DOI Author Url Publisher Url Public Url

Graves LE, Murphy RC, Shepherd SO, Cabot JA, Hopkins ND. 2015. Evaluation of sit-stand workstations in an office setting: A randomised controlled trial BMC Public Health, 15 :1-14 DOI Author Url Publisher Url Public Url

Shepherd SO, Wilson OJ, Taylor AS, Thøgersen-Ntoumani C, Adlan AM, Wagenmakers AJM, Shaw CS. 2015. Low-Volume High-Intensity Interval Training in a Gym Setting Improves Cardio-Metabolic and Psychological Health PLOS ONE, 10 :1-17 DOI Author Url Publisher Url Public Url

Cocks MS, Shaw CS, Shepherd SO, Fisher JP, Ranasinghe A, Baker TA, Wagenmakers AJM. 2015. Sprint interval and moderate-intensity continuous training have equal benefits on aerobic capacity, insulin sensitivity, muscle capillarisation and endothelial eNOS/NAD(P)Hoxidase protein ratio in obese men The Journal of Physiology, 594 :2307-2321 DOI Author Url Publisher Url Public Url

Wagenmakers AJM, Strauss JA, Shepherd SO, Keske MA, Cocks M. 2015. Increased muscle blood supply and transendothelial nutrient and insulin transport induced by food intake and exercise: effect of obesity and ageing. Journal of Physiology, :1-16 DOI Author Url Publisher Url Public Url

Cocks MS, Shaw CS, Shepherd SO, Fisher JP, Ranasinghe AM, Barker TA, Tipton KD, Wagenmakers AJM. 2014. Effect of Resistance Training on Microvascular Density and eNOS Content in Skeletal Muscle of Sedentary Men MICROCIRCULATION, 21 :738-746 DOI Author Url Publisher Url Public Url

Bradley H, Shaw CS, Worthington PL, Shepherd SO, Cocks MS, Wagenmakers AJM. 2014. Quantitative immunofluorescence microscopy of subcellular GLUT4 distribution in human skeletal muscle: effects of endurance and sprint interval training. Physiological Reports, 2 DOI Author Url Publisher Url Public Url

Shepherd SO, Cocks M, Tipton KD, Witard OC, Ranasinghe AM, Barker TA, Wagenmakers AJM, Shaw CS. 2014. Resistance training increases skeletal muscle oxidative capacity and net intramuscular triglyceride breakdown in type I and II fibres of sedentary males EXPERIMENTAL PHYSIOLOGY, 99 :894-908 DOI Author Url Publisher Url

Shaw CS, Clark JA, Shepherd SO. 2013. HSL and ATGL: The movers and shakers of muscle lipolysis Journal of Physiology, 591 :6137-6138 DOI Author Url Publisher Url

Cocks M, Shaw CS, Shepherd SO, Fisher JP, Ranasinghe AM, Barker TA, Tipton KD, Wagenmakers AJM. 2013. Sprint interval and endurance training are equally effective in increasing muscle microvascular density and eNOS content in sedentary males. J Physiol, 591 :641-656 DOI Author Url Publisher Url Public Url

Shepherd SO, Cocks M, Tipton KD, Ranasinghe AM, Barker TA, Burniston JG, Wagenmakers AJM, Shaw CS. 2013. Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5. J Physiol, 591 :657-675 DOI Author Url Publisher Url

Shaw CS, Shepherd SO, Wagenmakers AJM, Hansen D, Dendale P, van Loon LJC. 2012. Prolonged exercise training increases intramuscular lipid content and perilipin 2 expression in type I muscle fibers of patients with type 2 diabetes. Am J Physiol Endocrinol Metab, 303 :E1158-E1165 DOI Author Url Publisher Url

Cocks M, Shepherd SO, Shaw CS, Achten J, Costa ML, Wagenmakers AJM. 2012. Immunofluorescence microscopy to assess enzymes controlling nitric oxide availability and microvascular blood flow in muscle. Microcirculation, 19 :642-651 DOI Author Url Publisher Url

Shepherd SO, Cocks M, Tipton KD, Ranasinghe AM, Barker TA, Burniston JG, Wagenmakers AJM, Shaw CS. 2012. Preferential utilization of perilipin 2-associated intramuscular triglycerides during 1 h of moderate-intensity endurance-type exercise. Exp Physiol, 97 :970-980 DOI Author Url Publisher Url

preprint

Srisawat K, Stead C, Hesketh K, Pogson M, Strauss J, Cocks M, Siekmann I, Phillips S, Lisboa P, Shepherd S, Burniston J. 2023. Muscle of obese insulin-resistant humans exhibits losses in proteostasis and attenuated proteome dynamics that are improved by exercise training bioRxiv DOI Publisher Url

Baumert P, Temple S, Stanley JM, Cocks M, Strauss JA, Shepherd SO, Drust B, Lake MJ, Stewart CE, Erskine RM. 2019. Neuromuscular fatigue and recovery after strenuous exercise depends on skeletal muscle size and stem cell characteristics DOI Publisher Url

Chapters

Scott SN, Cocks M, Wagenmakers AJM, Shepherd SO, Riddell MC. 2020. Biochemistry of exercise training and type 1 diabetes The Routledge Handbook on Biochemistry of Exercise :479-498 9780367223830

Conference publication

Alowaish OR, Langan-Evans C, Shepherd S, Morton J. 2020. BOX-HIT IS PERCEIVED MORE ENJOYABLE AND AS PHYSIOLOGICALLY DEMANDING AS RUN-CONT AND HIT-RUN MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, American-College-of-Sports-Medicine (ACSM) Virtual Conference 52 :283-283 Author Url

Shepherd S, Jevons EFP, Strauss JA, Gejl KD, Jensen K, Hvid LG, Frandsen U, Sahlin K, Ortenblad N. 2019. Acute Carbohydrate Restriction During Recovery From Prolonged Exercise Enhances Intramuscular Triglyceride Resynthesis MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, Annual Meeting of the American-College-of-Sports-Medicine (ACSM) 51 :382-382 DOI Author Url Publisher Url

Strauss JA, Shepherd DA, Jevons EFP, Macey M, Shepherd SO. 2019. Bodipy Is Superior To Oil-red-O For Detecting And Quantifying Intramuscular Triglyceride In Human Skeletal Muscle MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, Annual Meeting of the American-College-of-Sports-Medicine (ACSM) 51 :719-719 DOI Author Url Publisher Url

Wagenmakers AJM, Hesketh K, Shepherd SO, Strauss JA, Low DA, Cooper RJ, Cocks M. 2019. Passive Heat Therapy in Sedentary Humans Improves Aerobic Capacity and Insulin Sensitivity via Increases in Skeletal Muscle Capillarisation and eNOS FASEB JOURNAL, Experimental Biology Meeting (EB) 33 Author Url

Macey M, Strauss JA, Shepherd SO. 2019. Fibre and region-specific differences in the subcellular distribution and morphology of lipid droplets in the skeletal muscle of trained, sedentary, obese males with Type 2 diabetes DIABETIC MEDICINE, 36 :49-49 Author Url

Langan-Evans C, Germaine M, Artukovic M, Oxborough D, Shepherd S, Close G, Morton J. 2018. Making Weight Safely: Manipulation of Energy Availability and Within Daily Energy Balance Without Symptoms of RED-S in an International Standard Male Taekwondo Athlete International Sport and Exercise Nutrition Conference

Gavin D, Millard A, Cochrane M, Hopkins N, Low D, Murphy R, Shepherd S, Watson P, Timpson H, Jones L, Haycox A, Collins B, Healy G, Edwardson C, Dunstan D, Graves L. 2018. Multi-level workplace intervention to improve cardiovascular outcomes in contact centre call agents: Study protocol JOURNAL OF PHYSICAL ACTIVITY & HEALTH, 15 :S155-S155 Author Url

Morris A, Murphy R, Shepherd S, Healy G, Edwardson C, Graves L. 2018. Move More, Sit Less: Using the MRC framework to develop a multi-level workplace intervention within a contact centre setting JOURNAL OF PHYSICAL ACTIVITY & HEALTH, 15 :S155-S155 Author Url

Langan-Evans C, Germaine M, Artukovic M, Oxborough D, Shepherd S, Close G, Morton J. 2018. Making Weight Safely: Manipulation of Energy Availability and Within Daily Energy Balance Without Symptoms of RED-S in an International Standard Male Taekwondo Athlete European College of Sport Sciences Congress

Langan-Evans C, Shepherd S, Close G, Morton J. 2017. Physiological Responses and Energy Expenditure Measurement During Taekwondo Pad-Work Bouts: Influence of Different Work:Rest Ratios. European College of Sport Science Congress

Langan-Evans C, Ellison M, Pugh J, Tod D, Scott M, Shepherd S, Close G, Morton J. 2016. Occurrence, Methods, Magnitudes and Influences of Acute and Chronic Body Mass Loss Practices Among International Standard Taekwondo Athletes of Differing Age Divisions International Sport and Exercise Nutrition Conference

Shepherd SO, Cocks M, Mellett NA, Meikle PJ, Wagenmakers AJM, Shaw CS. 2015. Increased PLIN Expression in Skeletal Muscle following Short-Term Exercise Training Is Linked to Lower Ceramide Concentrations and Improved Insulin Sensitivity DIABETES, 75th Scientific Sessions of the American-Diabetes-Association 64 :A77-A77 Author Url

Shepherd S, Cocks M, Ranasinghe A, Barker T, McClean A, Wagenmakers AJM, Shaw CS. 2014. High intensity interval and traditional endurance training both increase insulin sensitivity, V̇O2peak and skeletal muscle perilipin 2 and perilipin 5 content in sedentary obese males Japanese Journal of Physical Fitness and Sports Medicine, 63 :163 DOI Publisher Url

Shepherd S, Wilson O, Bradley H, Clark J, Cocks M, Thogersen-Ntoumani C, Taylor A, Anton W, Shaw C. 2013. Group-based High Intensity Interval Training Improves Adherence and Reduces Cardio-metabolic Risk Factors in Sedentary Individuals MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 60th Annual Meeting of the American-College-of-Sports-Medicine 45 :509-509 Author Url

Poster

Langan-Evans C, Germaine M, Artukovic M, Oxborough D, Shepherd S, Close G, Morton J. 2018. On the rebound: Symptoms of acute hyperphagia in an international level male Taekwondo athlete following chronic body mass loss International Sport and Exercise Nutrition Conference

Langan-Evans C, Naughton R, Scott M, Ellison M, Shepherd S, Close G, Morton J. 2017. Methods of Body Composition and Energy Expenditure Measurement in Male International Level Taekwondo Athletes International Sport and Exercise Nutrition Conference

Research Grants Awarded:

Dunhill Medical Trust, Understanding the role of obesity in the deterioration of skeletal muscle mass and quality in old age: New mechanistic insights, PI: Dr Leigh Breen (University of Birmingham), Prof Jamie McPhee (MMU), Prof Janice Thompson (University of Birmingham), Prof Jan Boren (University of Gothenburg), Dr Joachim Nielsen (University of Southern Denmark), Grant value (£): 228,342, Duration of research project: 3 years. 2018

Diabetes UK, Inhibition of adipose tissue lipolysis to enhance the effectiveness of a walking programme to improve insulin sensitivity in people with prediabetes, Professor Anton Wagenmakers (LJMU), Grant value (£): 97,888, Duration of research project: 3 years. 2017

Liverpool John Moores University - PhD Scholarship, High intensity interval training to improve glucose control in diabetes, Dr Matthew Cocks (Liverpool John Moores University), Prof Anton Wagenmakers (Liverpool John Moores University), Grant value (£): 57285, Duration of research project: 3 years. 2014

Diabetes Research & Wellness Foundation, Is high intensity interval training an efficient and effective form of exercise for people with type 1 diabetes?, Dr Matthew Cocks (LJMU), Prof Anton Wagenmakers (LJMU), Dr Parth Narendran (Uni of Birmingham), Dr Rob Andrews (Uni of Bristol), Dr Cecilie Thogersen-Ntoumani (Curtin Uni, Aus), Dr Ian Gallen (Royal Berkshire Hospital), Grant value (£): 19,811, Duration of research project: 12 months. 2014

Society for Endocrinology, Use of high-fat overfeeding to determine the early molecular changes in skeletal muscle that contribute to insulin resistance, Grant value (£): 9960, Duration of research project: 12 monrhs. 2014

Physiological Society, Summer studentship: Visualisation of SNAP23 translocation in skeletal muscle in response to glucose feeding using immunofluorescence microscopy, Grant value (£): 1,200, Duration of research project: 10 weeks. 2014

Teaching qualification:

Postgraduate Certificate in Learning & Teaching in HE. 2015

Award:

Resistance training increases skeletal muscle oxidative capacity and net intramuscular triglyceride breakdown in type I and II fibres of sedentary males, European College of Sport Science (ECSS) Young Investigator Award. 2014

High intensity interval and traditional endurance training both increase insulin sensitivity, VO2peak and skeletal muscle perilipin 2 and perilipin 5 content in sedentary obese males, European College of Sport Science (ECSS) Young Investigator Award. 2013

Preferential utilisation of perilipin 2 associated intramuscular triglycerides during one hour of moderate intensity endurance-type exercise, Physiological Society, Poster Communication (1st place). 2011

Preferential utilisation of perilipin 2 associated intramuscular triglycerides during one hour of moderate intensity endurance-type exercise, Physiological Society - Poster Prize (1st place). 2011

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