Cardio health

How increased core temperature affects the gut

Can you help us with this study?

This study is a student-led project as part of a PhD and the purpose of the research is to investigate how increased core temperature affects the ‘leakiness’ of the gut. The gut always has some degree of leakiness to allow nutrients to be absorbed, but under certain conditions, e.g. exercise or heat stroke, the leakiness of the gut can increase. Normally around 37°C, we want to investigate what happens in the gut when core temperature increases to between 38 and 39°C, and above 39°C.

Who can take part?

  • Male or female
  • Age 18-55 years
  • Training (endurance and/or resistance and/or combat sports type exercise for a minimum of four hours per week)
  • Non-smokers
  • Currently well (no cold or flu, etc.)
  • No history of diabetes, high cholesterol, uncontrolled asthma or history of heart disease
  • No history of and currently free from GI related clinical conditions (IBS, Crones Disease)
  • No history of and currently free from hypertension/hypotension related clinical conditions

What's involved in this study?

We will talk you through the study procedures and give you the chance to ask any questions. All research for the study will take place in the LJMU sports science laboratories and you will be required to make five visits to the laboratory. Each of these visits will last between one and three hours.

Contact details of researcher: Supervisor’s email address: