Image of Dr Alice McCloskey

Dr Alice McCloskey

Pharmacy and Biomolecular Sciences

Faculty of Science

Dr McCloskey is a Reader of Pharmacy, MPharm Programme leader, and co-lead of the Clinical Pharmacy and Therapeutics research group. She is a registered pharmacist of the GPhC and PSNI with a range of experience working across the three main sectors of pharmacy- clinical practice, academia and industry. Upon successful completion of her pre-registration training Dr McCloskey returned to Queen's University Belfast and completed a PhD in pharmaceutics where she developed 'Self-assembled Peptide Nanomaterials for the Prevention of Biomaterial Infection'. This was followed by an industry-academia collaborative post-doc between the Royal College of Surgeons in Ireland (RCSI, Dublin) and the Galway-based nebuliser company Aerogen, a global leader in aerosol delivery. This work was also linked with a national patient focused medical device research centre, CURAM based at The National University of Ireland, Galway. Dr McCloskey is a Fellow of the Royal Pharmaceutical Society and Fellow of HEA. Links are maintained with clinical pharmacy through regular days in practice both in hospital and community settings.

Research interests:
- Self-assembling nanostructures for biomedical applications
- Nanomaterials for drug delivery
- Pharmacy education- preparing students for 'real-life' practice
- Managing medicines in patients at the extremes of age

Degrees

2016, Queen's University Belfast, N. Ireland, PhD
2012, Queen's University Belfast, N. Ireland, MPharm

Certifications

RCSI, PgDip Health Professions Education

Highlighted publications

Hindley B, Lip GYH, McCloskey AP, Penson PE. 2023. Pharmacokinetics and pharmacodynamics of direct oral anticoagulants Expert Opinion on Drug Metabolism and Toxicology, DOI Author Url Publisher Url Public Url

Penson PE, McCloskey A. 2023. Therapeutic drug monitoring: applying the ‘Goldilocks Principle’ to clinical pharmacology Expert Review of Clinical Pharmacology, DOI Author Url Publisher Url

McCloskey AP, Malabar L, McCabe PG, Gitsham A, Jarman I. 2023. Antibiotic prescribing trends in primary care 2014–2022 Research in Social and Administrative Pharmacy, DOI Author Url Publisher Url Public Url

McCloskey AP, Bracken L, Vasey N, Ehtezazi T. 2023. 3D printing–an alternative strategy for pediatric medicines Expert Review of Clinical Pharmacology, 16 :613-616 DOI Author Url Publisher Url

Journal article

Chamani S, Mobasheri L, Zerehpoosh S, Naghizadeh A, McCloskey AP, Rizzo M, Jamialahmadi T, Sahebkar A. 2024. The Effect of Statins on the Differentiation and Function of Central Nervous System Cells Current Medicinal Chemistry, 31 :1348-1360 DOI Author Url Publisher Url

Pordel S, McCloskey AP, Almahmeed W, Sahebkar A. 2024. The protective effects of statins in traumatic brain injury Pharmacological Reports, DOI Author Url Publisher Url

Hindley B, Lip GYH, McCloskey AP, Penson PE. 2023. Pharmacokinetics and pharmacodynamics of direct oral anticoagulants Expert Opinion on Drug Metabolism and Toxicology, DOI Author Url Publisher Url Public Url

Ehtezazi T, Kteich A, Abdulkarim R, Lynch R, Algellay M, McCloskey AP, Roberts M, Sarker SD. 2023. Quantification of Linalool in 3D Printed Fast-Dissolving Oral Films by A High-Pressure Liquid Chromatography Method Journal of Natural Products Discovery, 2 :1-9 DOI Publisher Url Public Url

McCloskey AP, Malabar L, McCabe PG, Gitsham A, Jarman I. 2023. Antibiotic prescribing trends in primary care 2014–2022 Research in Social and Administrative Pharmacy, DOI Author Url Publisher Url Public Url

Rajabian A, McCloskey AP, Jamialahmadi T, Moallem SA, Sahebkar A. 2023. A review on the efficacy and safety of lipid-lowering drugs in neurodegenerative disease Reviews in the Neurosciences, DOI Author Url Publisher Url

McCloskey AP, Lunn A, Traynor MJ, Lim EJ, Tse Y, McCabe PG, Mistry RD, Vasey N, Pickering A, Rathbone AP. 2023. KidzMed e-learning to upskill student pharmacists to teach pill swallowing to children Peña-Fernández A. PLoS One, 18 DOI Author Url Publisher Url Public Url

McCloskey AP, Bracken L, Vasey N, Ehtezazi T. 2023. 3D printing–an alternative strategy for pediatric medicines Expert Review of Clinical Pharmacology, 16 :613-616 DOI Author Url Publisher Url

Mohammadpour F, Kamali H, Gholami L, McCloskey AP, Kesharwani P, Sahebkar A. 2022. Solid lipid nanoparticles: a promising tool for insulin delivery Expert Opinion on Drug Delivery, 19 :1577-1595 DOI Author Url Publisher Url

Chamani S, Kooshkaki O, Moossavi M, Rastegar M, Soflaei SS, McCloskey AP, Banach M, Sahebkar A. 2022. The effects of statins on the function and differentiation of blood cells Archives of Medical Science, 19 :1314-1326 DOI Author Url Publisher Url Public Url

Hatamipour M, Hadizadeh F, Jaafari MR, Khashyarmanesh Z, Kesharwani P, McCloskey AP, Sahebkar A. 2022. Formulation development and in vitro–in vivo anticancer potential of novel nanoliposomal fluorinated curcuminoids Process Biochemistry, 122 :250-257 DOI Publisher Url

McCloskey AP, Penson PE, Tse Y, Abdelhafiz MA, Ahmed SN, Lim EJ. 2022. Identifying and addressing pill aversion in adults without physiological‐related dysphagia: A narrative review British Journal of Clinical Pharmacology, DOI Author Url Publisher Url Public Url

Odeh M, Alkhader E, McCloskey A, Aljabra R, Al-sharayri M, Al-Noimi F, Alarmooti M, Alzu’bi M. 2021. Postgraduate pharmacist development- an evaluation of Jordanian pharmacist experiences to inform and shape an evidence-based professional development policy PLoS One, 16 DOI Author Url Publisher Url Public Url

McCloskey AP, Brown J, Haughey S, O'Hare R. 2019. Pharmacy student and pharmacist perceptions of professional socialism and communication in a real-life clinical setting International Journal of Pharmacy Practice, 27 :286-294 DOI Author Url Publisher Url

Sweeney L, McCloskey AP, Higgins G, Ramsey JM, Cryan SA, MacLoughlin R. 2019. Effective nebulization of interferon-γ using a novel vibrating mesh Respiratory Research, 20 DOI Author Url Publisher Url Public Url

McCloskey AP, Lee M, Megaw J, McEvoy J, Coulter SM, Pentlavalli S, Laverty G. 2019. Investigating the In Vivo Antimicrobial Activity of a Self-Assembling Peptide Hydrogel Using a Galleria mellonella Infection Model ACS Omega, 4 :2584-2589 DOI Author Url Publisher Url Public Url

McCloskey AP, Draper ER, Gilmore BF, Laverty G. 2017. Ultrashort self-assembling Fmoc-peptide gelators for anti-infective biomaterial applications JOURNAL OF PEPTIDE SCIENCE, 23 :131-140 DOI Author Url Publisher Url

Huwaitat R, McCloskey AP, Gilmore BF, Laverty G. 2016. Potential strategies for the eradication of multidrug-resistant Gram-negative bacterial infections FUTURE MICROBIOLOGY, 11 :955-972 DOI Author Url Publisher Url

Rafferty J, Nagaraj H, McCloskey AP, Huwaitat R, Porter S, Albadr A, Laverty G. 2016. Peptide Therapeutics and the Pharmaceutical Industry: Barriers Encountered Translating from the Laboratory to Patients CURRENT MEDICINAL CHEMISTRY, 23 :4231-4259 DOI Author Url Publisher Url

McCloskey AP, Gilmore SM, Zhou J, Draper ER, Porter S, Gilmore BF, Xu B, Laverty G. 2016. Self-assembling ultrashort NSAID-peptide nanosponges: multifunctional antimicrobial and anti-inflammatory materials RSC ADVANCES, 6 :114738-114749 DOI Author Url Publisher Url

Laverty G, McCloskey AP, Gorman SP, Gilmore BF. 2015. Anti-biofilm activity of ultrashort cinnamic acid peptide derivatives against medical device-related pathogens JOURNAL OF PEPTIDE SCIENCE, 21 :770-778 DOI Author Url Publisher Url

McCloskey AP, Gilmore BF, Laverty G. 2014. Evolution of antimicrobial peptides to self-assembled peptides for biomaterial applications Pathogens, 3 :792-821 DOI Author Url Publisher Url

Laverty G, McCloskey AP, Gilmore BF, Jones DS, Zhou J, Xu B. 2014. Ultrashort Cationic Naphthalene-Derived Self-Assembled Peptides as Antimicrobial Nanomaterials BIOMACROMOLECULES, 15 :3429-3439 DOI Author Url Publisher Url

Ehtezazi T, Kteich A, Abdulkarim R, Anderson V, Algellay M, McCloskey AP, Carter N, Roberts M, Assi S, Al-Jumeily D, Thompson M, Mohamed FA, Sarker SD. Reducing temperature of fused deposition modelling 3D printing for linalool fast dissolving oral films by increasing printer nozzle diameter Journal of Pharmaceutical Sciences, Public Url

Conference publication

Ehtezazi T, Kelly N, McCloskey A, Sarker S. 2023. USE OF NATURAL PRODUCTS IN 3D PRINTING OF MEDICINAL TEDDY BEARS Journal of Natural Products Discovery, 4th Annual CNPD (Centre for Natural Products Discovery) Conference 2 :7-7 DOI

Parker E, Sawyer M, McCloskey A, Vasey N, Tse Y, Lim E. 2023. 729 EcoKidzMed: Measuring the carbon emissions of packaging, distribution and waste disposal of liquid and capsule amoxicillin Climate Change Working Group, Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference, Glasgow, 23–25 May 2023 DOI Publisher Url

Thompson M, Assi S, Obe DAJ, McCloskey AP, Sarker SD, Tang L, Mohamed FA, Wilson M, Ehtezazi T. 2023. Use of Raman and Fourier Transform Infrared Spectroscopy as a Quality Control of 3D printed Linalool Fast Dissolving Oral Films Proceedings - International Conference on Developments in eSystems Engineering, DeSE, :498-503 DOI Publisher Url

Traynor M, Kinder L, Penson P, McCloskey A, Aragon Cuevas O. 2022. 1300 Transfer of outpatient paediatric prescriptions to primary care via the Electronic Prescription Service (EPS)- community pharmacist views Abstracts, Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference, Liverpool, 28–30 June 2022 DOI Publisher Url

McCloskey A, Upadhyay B, Leonard O, Parker H, Traynor M, Aragon O. 2022. 1313 Has COVID-19 impacted the global fight against adolescent obesity? British Association of Child and Adolescent Public Health, Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference, Liverpool, 28–30 June 2022 DOI Publisher Url

McCloskey AP, Maxwell S, Do H, Sabbagh L, Rathbone AP. 2021. 761 Optimal management of minor ailments in children: healthcare professionals’ views Abstracts, Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference–Online, 15 June 2021–17 June 2021 DOI Publisher Url

Brogan NM, McCloskey AP. 2021. 823 Pharmacy KIDS – pharmacy students’ knowledge identifying and managing minor ailments in children Abstracts, Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference–Online, 15 June 2021–17 June 2021 DOI Publisher Url

Gaul R, Murphy R, McCloskey A, De Santi C, Joanne R, Andreas H, Sally Ann C. 2019. Development of an anti-inflammatory star-polypetide microRNA delivery system with therapeutic applications in cystic fibrosis. 42nd European Cystic Fibrosis Conference

Sweeney L, Higgins G, Ramsey J, McCloskey A, MacLoughlin R, Cryan S-A. 2017. HARNESSING NEW PROTOTYPE VIBRATING MESH NEBULIZER'S FOR EFFECTIVE RESPIRATORY DELIVERY OF IFN-Y JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 30 :32-32 Author Url

Rowley R, Gill A, MacFarlane K, McCloskey A. P14 Identification of prescribing errors in a paediatric intensive care unit (PICU): an audit Archives of Disease in Childhood, The 27th annual THE NEONATAL AND PAEDIATRIC PHARMACISTS CONFERENCE 2021 Publisher Url

McCloskey A, Davies J, Traynor M, Tse Y, Lim E, Vasey N. Embedding ‘pill’ swallowing training across a UK School of Pharmacy Neonatal and Paediatric Pharmacists Conference 2022

McCloskey A, Traynor M, Lunn A, lim E, tse Y, vasey N, rathbone A. Teaching pharmacy students how to support patients who struggle swallowing solid oral dosage forms (SODFs) The 80th World Congress of Pharmacy and Pharmaceutical Sciences

Editorial/letter to the editor

Penson PE, McCloskey A. 2023. Therapeutic drug monitoring: applying the ‘Goldilocks Principle’ to clinical pharmacology Expert Review of Clinical Pharmacology, DOI Author Url Publisher Url

Penson PE, Banach M, McCloskey AP. 2023. Which Statin is Best for the Kidneys? Current Vascular Pharmacology, 21 :1-3 DOI Author Url Publisher Url

Dataset

McCloskey A, Lunn A, Traynor M, Lim E, Tse Y, McCabe P, Mistry R, Vasey N, Pickering A, Rathbone A. 2023. KidzMed E-learning to upskill student pharmacists to teach pill swallowing to children questionnaire data DOI Public Url

Chapters

McCloskey A, Penson PE. 2023. Long COVID-19 - Definition, Epidemiology, and Clinical Implications Banach M. Cardiovascular Complications of COVID-19: Acute and Long-Term Impacts :367-367 Springer Nature 978-3031154775 DOI Publisher Url

Ramsey J, McCloskey A, Gaul R, Fernandez Fernandez E, Sweeney L, Greene C, MacLoughlin R, Cryan S-A. 2020. Respiratory Drug/Vaccine Delivery Using Nanoparticles Muttil P, Kunda N. Mucosal Delivery of Drugs and Biologics in Nanoparticles :125-154 Springer 9783030359096 DOI Publisher Url

Poster

Ireland C, Aragon Cuevas O, McCloskey A. 2022. Precision Medicines in Practice: The Connection Between CFTR Modulators and Deranged Liver Enzymes The NPPG 29th annual professional conference & exhibition

Gitsham A, Rainsley A, Shemilt K, McCloskey A, Gibson J. 2022. Changes in breast cancer patients’ weight with adjuvant palbociclib treatment – a retrospective review. The 25th BOPA Annual Symposium

Lunn AM, Burkle DM, Ward R, McCloskey AP, Rathbone A, Courtenay A, Mullen R, Manfrin A. 2021. Spoken propositional idea density, a measure to help second language English speaking students: A multicentre cohort study Author Url Public Url

McCloskey AP, Gilmore SM, Porter S, Gilmore BF, Laverty G. 2016. Ultrashort Peptides as Bifunctional Nanomaterials. Congrès PepMat 2016

McCloskey AP, Lee M, McCallion J, Gartland K, Gilmore BF, Laverty G. 2015. Ultrashort Self-assembling Peptide Nanomaterials for Biomedical Applications International Meeting on Antimicrobial Peptides, Royal Society of Chemistry, London

McCloskey AP, Gilmore BF, Laverty G. 2015. Fulfilling the 3Rs: Galleria mellonella as an In Vivo Model to Assess the Antimicrobial Efficacy of Self-assembling Peptide Hydrogels 37th All Ireland Schools of Pharmacy Conference

McCloskey AP, Glass E, Catterson P, Gilmore BF, Laverty G. 2015. Self-assembled Fmoc Peptide Hydrogels as Potential Antimicrobials. Nanopeptide 2015, University of Strathclyde, Glasgow

McCloskey A, Gilmore SM, Gilmore BF, Laverty G. 2015. Self-assembling Ultrashort Cationic Peptides as Dual Antimicrobial and Anti-inflammatory Nanomaterials Nanopeptide 2015, University of Strathclyde, Glasgow,

McCloskey A, Gilmore BF, Laverty G. 2014. Ultrashort Cationic Self-assembled Peptides for the Prevention of Medical Device Related Infection. 36th All Ireland Schools of Pharmacy Conference, Trinity College, Dublin,

Shaw G, Gilmore BF, McCloskey AP. 2013. Sortase Inhibition- An Antibiofilm Strategy in Streptococci. 3rd European Congress on Microbial Biofilms- Basic and Clinical Aspects, Ghent, Belgium

Gitsham A, Mack L, Shemilt K, McCloskey A, Gibson J. Changes in breast cancer patients’ weight with adjuvant goserelin treatment – a retrospective review The 25th BOPA Annual Symposium

Film

Tomlin S, Terry D, Lim E, McCloskey A. 2022. RCPCH and RPS joint College webinar: The why and how of pill swallowing- patient and safety considerations Publisher Url

Other

McCloskey A, Tse Y, Lim E. PROSPERO 2021 CRD42021227095 Identifying and addressing pill aversion in adults without physiological-related dysphagia: a systematic review Publisher Url

Lim E, Tse Y, McCloskey A. RCPCH Conference 2022 Lunchtime Workshop: KidzMed- The why, how to, and what next of taking pills

McCloskey A. Heart UK Conference 2022: Meet the Expert Taster Session: Discussing the barriers to medication adherence as a result of difficulties taking lipid-lowering medication.

McCloskey A. LJMU Institute for Health Research Children, Young People and Families Health Research Showcase - KidzMed: Supporting children and young people to swallow pills

Editorial boards:

Expert Review of Clinical Pharmacology. 2023

Exploratory Research in Clinical and Social Pharmacy, Editorial Board Member. 2020

Membership of professional bodies:

Fellow, The Royal Pharmaceutical Society. 2023

Member, The Neonatal and Paediatric Pharmacists Group. 2019

Member, Society for Applied Microbiology. 2013

Fellowships:

Fellow of the Higher Education Academy., Advance HE. 2019

Teaching qualification:

PGDip Health Professions Education. 2018

Other Professional Activity:

Peer reviewer British Journal of Clinical Pharmacology.

Peer reviewer Dose Response.

Peer reviewer Journal of peptide science.

Peer reviewer Pharmacy Research UK.

Peer reviewer Polymer.

Peer reviewer Reviews in Medical Virology.

STEM ambassador.

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