Liverpool Skylilne

Pharmacy and Biomolecular Sciences

Dr Gordon Lowe

Dr Gordon Lowe

Telephone: 0151 231 2142

Publications

Chapters

Lowe G, Graham D, Young AJ. 2018. Lycopene Chemistry, Metabolism, and Bioavailability Rao AV, Young G, Rao L. Lycopene in Human Health and Nutrition CRC Press. Boca Raton 978-1-4665-7537-0

Journal article

Graham DL, Young AJ, Lorenz M, Lowe . 2017. A Possible Indicator of Oxidative Damage in Smokers: (13Z)-Lycopene? Antioxidants, 6 >DOI

Young AJ, pritchard J, lowe , Buttle L, Crampton V. 2017. Reconstitution of muscle F-actin from Atlantic salmon (Salmo salar L.) with carotenoids – binding characteristics of astaxanthin and canthaxanthin. Aquaculture Nutrition, :1-8 >DOI

Rahman K, Lowe GM, Smith S. 2016. Aged Garlic Extract Inhibits Human Platelet Aggregation by Altering Intracellular Signaling and Platelet Shape Change JOURNAL OF NUTRITION, 146 :410S-415S >DOI >Link

Lowe GM, Muller L, Caris-Veyrat C, Bohm V. 2015. Lycopene and Its Antioxidant Role in the Prevention of Cardiovascular Diseases - A Critical Review. Crit Rev Food Sci Nutr,

Lowe GM, Gana K, Rahman K. 2015. Dietary supplementation with green tea extract promotes enhanced human leukocyte activity Journal of Complementary and Integrative Medicine, 12 :277-282 >DOI

Chew PY, Riley L, Graham DL, Rahman K, Lowe GM. 2012. Does lycopene offer human LDL any protection against myeloperoxidase activity? Molecular and cellular biochemistry, 361 :181-187

Allison GL, Lowe GM, Rahman K. 2012. Aged garlic extract inhibits platelet activation by increasing intracellular cAMP and reducing the interaction of GPIIb/IIIa receptor with fibrinogen LIFE SCIENCES, 91 :1275-1280 >DOI >Link

Graham DL, Carail M, Caris-Veyrat C, Lowe GM. 2012. (13Z)- and (9Z)-lycopene isomers are major intermediates in the oxidative degradation of lycopene by cigarette smoke and Sin-1. Free Radic Res, 46 :891-902 >DOI >Link

Chew PY, Riley L, Graham DL, Rahman K, Lowe GM. 2012. Does lycopene offer human LDL any protection against myeloperoxidase activity? Mol Cell Biochem, 361 :181-187 >DOI >Link

Chew PY, Riley L, Graham DL, Rahman K, Lowe GM. 2011. Does lycopene offer human LDL any protection against myeloperoxidase activity? Molecular and Cellular Biochemistry, :1-7 >DOI

Graham DL, Carail M, Caris-Veyrat C, Lowe GM. 2010. Cigarette smoke and human plasma lycopene depletion. Food Chem Toxicol, 48 :2413-2420 >DOI >Link

Lowe GM, Holmes E, Davies I. 2009. Circulating ghrelin exists in both lipoprotein bound and free forms. Ann Clin Biochem, 46 :514-516

Lowe GM. 2009. Lycocard-In Vitro Studies : an update Acta Horticulturae, 823 :169-172

Lowe GM, Vlismas K, Graham DL, Carail M, Caris-Veyrat C, Young AJ. 2009. The degradation of (all-E)-beta-carotene by cigarette smoke. Free Radic Res, 43 :280-286 >DOI

Allison GL, Lowe GM, Rahman K. 2006. Aged garlic extract may inhibit aggregation in human platelets by suppressing calcium mobilization. J Nutr, 136 :789S-792S >Link

Allison GL, Lowe GM, Rahman K. 2006. Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms. J Nutr, 136 :782S-788S >Link

Rahman K, Lowe GM. 2006. Garlic and cardiovascular disease: a critical review. J Nutr, 136 :736S-740S >Link

El-Agamey A, Lowe GM, McGarvey DJ, Mortensen A, Phillip DM, Truscott TG, Young AJ. 2004. Carotenoid radical chemistry and antioxidant/pro-oxidant properties ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 430 :37-48 >DOI >Link

Harvey D, Lowe GM. 2004. Factor V leiden: association with venous thromboembolism in pregnancy and screening issues BRITISH JOURNAL OF BIOMEDICAL SCIENCE, 61 :157-164 >DOI >Link

Gana K, Rahman K, Lowe GM. 2003. Immunomodulation of isolated human neutrophils by a green tea extract Journal of Nutraceuticals, Functional and Medical Foods, 4 :15-26 >DOI

Dillon SA, Burmi RS, Lowe GM, Billington D, Rahman K. 2003. Antioxidant properties of aged garlic extract: an in vitro study incorporating human low density lipoprotein. Life Sci, 72 :1583-1594 >Link

Lowe GM, Vlismas K, Young AJ. 2003. Carotenoids as prooxidants? Mol Aspects Med, 24 :363-369 >Link

Dillon SA, Lowe GM, Billington D, Rahman K. 2002. Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin F(2 alpha) in smoking and nonsmoking men and women. J Nutr, 132 :168-171 >DOI >Link

Hosker BS, Bilton RF, Lowe GM, Loweth AC. 2001. Quantification of the contribution of peroxynitrite to mixed radical- and nitric oxide-mediated beta cell death DIABETOLOGIA, 44 :A144-A144 >Link

Young AJ, Lowe GM. 2001. Antioxidant and prooxidant properties of carotenoids. Arch Biochem Biophys, 385 :20-27 >DOI >Link

Lowe GM, Booth LA, Young AJ, Bilton RF. 1999. Lycopene and beta-carotene protect against oxidative damage in HT29 cells at low concentrations but rapidly lose this capacity at higher doses. Free Radic Res, 30 :141-151 >Link

Lowe GM, Bilton RF, Davies IG, Ford TC, Billington D, Young AJ. 1999. Carotenoid composition and antioxidant potential in subfractions of human low-density lipoprotein. Ann Clin Biochem, 36 ( Pt 3) :323-332 >DOI >Link

Lowe GM, Hulley CE, Rhodes ES, Young AJ, Bilton RF. 1998. Free radical stimulation of tyrosine kinase and phosphatase activity in human peripheral blood mononuclear cells. Biochem Biophys Res Commun, 245 :17-22 >DOI >Link

Lowe GM, Slupsky JR, Galvani DW. 1996. GTPgammaS-stimulated phospholipase D activation in human neutrophils occurs by protein kinase C-dependent and -independent pathways but not tyrosine kinases. Biochem Biophys Res Commun, 220 :484-490

Lowe GM, Bilton RF, Young AJ, Graham JM, Ford TC, Billington D. 1996. Carotenoid profiles of human plasma lipoproteins. Biochem Soc Trans, 24 :171S >Link

Lowe GM, Laing GD, Kamiguti AS, Wilkinson MC. 1995. Characterisation of a purified phospholipase A2 from the venom of the Papuan black snake (Pseudechis papuanus). Biochim Biophys Acta, 1250 :137-143

Graham DL, Lowe GM, Phipps DA, Bilton RF. 1991. Two novel methods used in the biodegradation of bile acids and plant sterols. Biochem Soc Trans, 19 :52S >Link

Conference publication

Holmes E, Davies IG, Lowe G, Ranganath L. 2008. TRANSPORT OF GHRELIN AND OBESTATIN IN PLASMA Atherosclerosis Supplements, 1 :26-27 >DOI

Allison GL, Lowe GM, Rahman K. 2006. Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms Journal of Nutrition, 136

Allison GL, Lowe GM, Rahman K. 2006. Aged garlic extract may inhibit aggregation in human platelets by suppressing calcium mobilization Journal of Nutrition, 136

Rahman K, Lowe GM. 2006. Garlic and cardiovascular disease: A critical review Journal of Nutrition, 136

Lowe GM, Rahman K. 2003. Immunomodulation of isolated neutrophils by a green tea extract. FREE RADICAL RESEARCH, Meeting on Free Radicals and Oxidative Stress 37 :69-69 >Link

Hosker BS, Bilton RF, Lowe GM, Loweth AC. 2003. Sequential nitrosylation, p38MAPK activation and apoptosis in RINm5F beta-cells in response to nitric oxide DIABETOLOGIA, 18th Congress of the International-Diabetes-Federation 46 :A185-A186 >Link

Dillon SA, Lowe GM, Billington D, Rahman K. 2002. Dietary supplementation with aged garlic extract reduces plasma and urinary concentrations of 8-iso-prostaglandins in smokers JOURNAL OF NUTRITION, International Research Conference on Food, Nutrition and Cancer 132 :3549S-3549S >Link

Hosker BS, Bilton RF, Lowe GM, Loweth AC. 2002. A spectrophotometric method for measuring S-nitrosylation of proteins in RINm5F cells. DIABETOLOGIA, 38th EASD Annual Meeting of the European-Association-for-the-Study-of-Diabetes 45 :A172-A173 >Link