Liverpool Skylilne

Pharmacy and Biomolecular Sciences

Dr Gordon Lowe

Dr Gordon Lowe

Telephone: 0151 231 2142

Publications

Journal article

Lucas R, Mihály J, Lowe GM, Graham DL, Szklenar M, Szegedi A, Töröcsik D, Rühl R. 2018. Reduced Carotenoid and Retinoid Concentrations and Altered Lycopene Isomer Ratio in Plasma of Atopic Dermatitis Patients. Nutrients, 10 DOI Author Url Publisher Url Public Url

Sirichaiwetchakoon K, Lowe GM, Thumanu K, Eumkeb G. 2018. The Effect of Pluchea indica (L.) Less. Tea on Adipogenesis in 3T3-L1 Adipocytes and Lipase Activity Evidence-Based Complementary and Alternative Medicine, DOI Author Url Publisher Url Public Url

Hengpratom T, Lowe GM, Thumanu K, Suknasang S, Tiamyom K, Eumkeb G. 2018. Oroxylum indicum (L.) Kurz extract inhibits adipogenesis and lipase activity in vitro BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 18 DOI Author Url Public Url

Young AJ, pritchard J, lowe , Buttle L, Crampton V. 2017. Reconstitution of muscle F-actin from Atlantic salmon (Salmo salar L.) with carotenoids – binding characteristics of astaxanthin and canthaxanthin. Aquaculture Nutrition, 23 :1296-1303 DOI Author Url Publisher Url Public Url

Graham DL, Young AJ, Lorenz M, Lowe . 2017. A Possible Indicator of Oxidative Damage in Smokers: (13Z)-Lycopene? Antioxidants, 6 DOI Author Url Public Url

Rahman K, Lowe GM, Smith S. 2016. Aged Garlic Extract Inhibits Human Platelet Aggregation by Altering Intracellular Signaling and Platelet Shape Change Journal of Nutrition, 146 :410S-415S DOI Author Url Publisher Url

Lowe GM, Muller L, Caris-Veyrat C, Bohm V. 2015. Lycopene and Its Antioxidant Role in the Prevention of Cardiovascular Diseases - A Critical Review. Crit Rev Food Sci Nutr,

Lowe GM, Gana K, Rahman K. 2015. Dietary supplementation with green tea extract promotes enhanced human leukocyte activity Journal of Complementary and Integrative Medicine, 12 :277-282 DOI Author Url Public Url

Allison GL, Lowe GM, Rahman K. 2012. Aged garlic extract inhibits platelet activation by increasing intracellular cAMP and reducing the interaction of GPIIb/IIIa receptor with fibrinogen LIFE SCIENCES, 91 :1275-1280 DOI Author Url

Chew PY, Riley L, Graham DL, Rahman K, Lowe GM. 2012. Does lycopene offer human LDL any protection against myeloperoxidase activity? Molecular and cellular biochemistry, 361 :181-187 DOI

Chew PY, Riley L, Graham DL, Rahman K, Lowe GM. 2011. Does lycopene offer human LDL any protection against myeloperoxidase activity? Molecular and Cellular Biochemistry, :1-7 DOI

Lowe G, Rahman K. 2007. Nutraceuticals and health Food Science and Technology, 21 :30-31

El-Agamey A, Lowe GM, McGarvey DJ, Mortensen A, Phillip DM, Truscott TG, Young AJ. 2004. Carotenoid radical chemistry and antioxidant/pro-oxidant properties ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 430 :37-48 DOI Author Url

Harvey D, Lowe GM. 2004. Factor V leiden: association with venous thromboembolism in pregnancy and screening issues BRITISH JOURNAL OF BIOMEDICAL SCIENCE, 61 :157-164 DOI Author Url

Gana K, Rahman K, Lowe GM. 2003. Immunomodulation of isolated human neutrophils by a green tea extract Journal of Nutraceuticals, Functional and Medical Foods, 4 :15-26 DOI

Dillon SA, Burmi RS, Lowe GM, Billington D, Rahman K. 2003. Antioxidant properties of aged garlic extract: an in vitro study incorporating human low density lipoprotein. Life Sci, 72 :1583-1594 DOI Author Url

Hosker BS, Bilton RF, Lowe GM, Loweth AC. 2001. Quantification of the contribution of peroxynitrite to mixed radical- and nitric oxide-mediated beta cell death DIABETOLOGIA, 44 :A144-A144 Author Url

Young AJ, Lowe GM. 2001. Antioxidant and prooxidant properties of carotenoids. Arch Biochem Biophys, 385 :20-27 DOI Author Url

Lowe GM, Hulley CE, Rhodes ES, Young AJ, Bilton RF. 1998. Free radical stimulation of tyrosine kinase and phosphatase activity in human peripheral blood mononuclear cells. Biochem Biophys Res Commun, 245 :17-22 DOI Author Url

Lowe GM, Vlismas K, Graham DL, Carail M, Caris-Veyrat C, Young AJ. The degradation of (all-E)-beta-carotene by cigarette smoke. Free Radic Res, 43 :280-286 DOI Author Url

Lowe GM. Lycocard-In Vitro Studies : an update Acta Horticulturae, 823 :169-172 DOI Author Url

Lowe GM, Holmes E, Davies I. Circulating ghrelin exists in both lipoprotein bound and free forms. Ann Clin Biochem, 46 :514-516 DOI Author Url

Rahman K, Lowe GM. Garlic and cardiovascular disease: a critical review. J Nutr, 136 :736S-740S DOI Author Url

Allison GL, Lowe GM, Rahman K. Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms. J Nutr, 136 :782S-788S DOI Author Url

Allison GL, Lowe GM, Rahman K. Aged garlic extract may inhibit aggregation in human platelets by suppressing calcium mobilization. J Nutr, 136 :789S-792S DOI Author Url

Lowe GM, Vlismas K, Young AJ. Carotenoids as prooxidants? Mol Aspects Med, 24 :363-369 DOI Author Url

Dillon SA, Lowe GM, Billington D, Rahman K. Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin F(2 alpha) in smoking and nonsmoking men and women. J Nutr, 132 :168-171 DOI Author Url

Lowe GM, Bilton RF, Davies IG, Ford TC, Billington D, Young AJ. Carotenoid composition and antioxidant potential in subfractions of human low-density lipoprotein. Ann Clin Biochem, 36 ( Pt 3) :323-332 DOI Author Url

Lowe GM, Booth LA, Young AJ, Bilton RF. Lycopene and beta-carotene protect against oxidative damage in HT29 cells at low concentrations but rapidly lose this capacity at higher doses. Free Radic Res, 30 :141-151 DOI Author Url

Lowe GM, Bilton RF, Young AJ, Graham JM, Ford TC, Billington D. Carotenoid profiles of human plasma lipoproteins. Biochem Soc Trans, 24 :171S DOI Author Url

Lowe GM, Slupsky JR, Galvani DW. GTPgammaS-stimulated phospholipase D activation in human neutrophils occurs by protein kinase C-dependent and -independent pathways but not tyrosine kinases. Biochem Biophys Res Commun, 220 :484-490

Graham DL, Lowe GM, Phipps DA, Bilton RF. Two novel methods used in the biodegradation of bile acids and plant sterols. Biochem Soc Trans, 19 :52S DOI Author Url

Chew PY, Riley L, Graham DL, Rahman K, Lowe GM. Does lycopene offer human LDL any protection against myeloperoxidase activity? Mol Cell Biochem, 361 :181-187 DOI Author Url

Graham DL, Carail M, Caris-Veyrat C, Lowe GM. (13Z)- and (9Z)-lycopene isomers are major intermediates in the oxidative degradation of lycopene by cigarette smoke and Sin-1. Free Radic Res, 46 :891-902 DOI Author Url

Graham DL, Carail M, Caris-Veyrat C, Lowe GM. Cigarette smoke and human plasma lycopene depletion. Food Chem Toxicol, 48 :2413-2420 DOI Author Url

Lowe GM, Laing GD, Kamiguti AS, Wilkinson MC. Characterisation of a purified phospholipase A2 from the venom of the Papuan black snake (Pseudechis papuanus). Biochim Biophys Acta, 1250 :137-143

Chapters

Lowe G, Graham D, Young AJ. 2018. Lycopene Chemistry, Metabolism, and Bioavailability Rao AV, Young G, Rao L. Lycopene in Human Health and Nutrition CRC Press. Boca Raton 978-1-4665-7537-0

Young AJ, Phillip DM, Lowe GM. 2004. Carotenoid antioxidant activity Krinsky NI, Mayne ST, Sies H. Carotenoids in health and disease :105-126 CRC. New York 9780824754167

Conference publication

Holmes E, Davies IG, Lowe G, Ranganath L. 2008. TRANSPORT OF GHRELIN AND OBESTATIN IN PLASMA Atherosclerosis Supplements, 1 :26-27 DOI

Allison GL, Lowe GM, Rahman K. 2006. Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms Journal of Nutrition, 136

Allison GL, Lowe GM, Rahman K. 2006. Aged garlic extract may inhibit aggregation in human platelets by suppressing calcium mobilization Journal of Nutrition, 136

Rahman K, Lowe GM. 2006. Garlic and cardiovascular disease: A critical review Journal of Nutrition, 136

Hosker BS, Bilton RF, Lowe GM, Loweth AC. 2003. Sequential nitrosylation, p38MAPK activation and apoptosis in RINm5F beta-cells in response to nitric oxide DIABETOLOGIA, 18th Congress of the International-Diabetes-Federation 46 :A185-A186 Author Url

Lowe GM, Rahman K. 2003. Immunomodulation of isolated neutrophils by a green tea extract. FREE RADICAL RESEARCH, Meeting on Free Radicals and Oxidative Stress 37 :69-69 Author Url

Dillon SA, Lowe GM, Billington D, Rahman K. 2002. Dietary supplementation with aged garlic extract reduces plasma and urinary concentrations of 8-iso-prostaglandins in smokers JOURNAL OF NUTRITION, International Research Conference on Food, Nutrition and Cancer 132 :3549S-3549S Author Url

Hosker BS, Bilton RF, Lowe GM, Loweth AC. 2002. A spectrophotometric method for measuring S-nitrosylation of proteins in RINm5F cells. DIABETOLOGIA, 38th EASD Annual Meeting of the European-Association-for-the-Study-of-Diabetes 45 :A172-A173 Author Url