Liverpool Skylilne

Pharmacy and Biomolecular Sciences

Dr Simon Brandt

Dr Simon Brandt

Telephone: 0151 231 2184

Biography

Simon D. Brandt is a Reader in Bioactive Drug Chemistry. His research activities and interests focus on the chemistry, analytical and pharmacological properties of psychoactive substances, "legal highs", drugs of abuse and so-called designer drugs, within the context of (psycho)pharmacology, medicinal chemistry, psychiatry, forensic science and public health.

He obtained a Diploma in Biochemistry/Molecular Biology (1999) with further specialisation in cell structures and pharmacology/toxicology at the University of Hamburg (Germany). He holds a PhD in Analytical Chemistry (2004) from The University of Manchester (formerly UMIST) (United Kingdom). He serves as an Associate Editor of the Wiley journal “Drug Testing and Analysis”. Since 2011, and in collaboration with LJMU’s Public Health Institute, Simon functions as a coordinator of the UK Early-Warning System on New Psychoactive Substances run by Public Health England.

Simon serves as a scientific advisor in questions related to risk assessment and scheduling recommendations associated with new psychoactive substances. He is an extended Member of the Scientific Committee of the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) and serves as an expert technical advisor to the World Health Organisation’s (WHO) Expert Committee on Drug Dependence (ECDD). In June 2016, Simon was awarded the LJMU Impact Award 2016 for his contributions made to the fields of international drugs legislation and policy making.

Publications

Highlighted publications

Nichols DE, Sassano MF, Halberstadt AL, Klein LM, Brandt SD, Elliott SP, Fiedler WJ. 2015. N -Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT<inf>2</inf> Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues ACS Chemical Neuroscience, 6 :1165-1175 >DOI

Baumann MH, Partilla JS, Lehner KR, Thorndike EB, Hoffman AF, Holy M, Rothman RB, Goldberg SR, Lupica CR, Sitte HH, Brandt SD, Tella SR, Cozzi NV, Schindler CW. 2013. Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive ‘Bath Salts’ Products Neuropsychopharmacology, 38 :552-562 >DOI

Passie T, Emrich HM, Karst M, Brandt SD, Halpern JH. 2012. Mitigation of post-traumatic stress symptoms by Cannabis resin: A review of the clinical and neurobiological evidence Brandt SD, Passie T. Drug Testing and Analysis, 4 :649-659 >DOI

Baumann MH, Ayestas MA, Partilla JS, Sink JR, Shulgin AT, Daley PF, Brandt SD, Rothman RB, Ruoho AE, Cozzi NV. 2012. The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue Neuropsychopharmacology, 37 :1192-1203 >DOI

Brandt SD, Sumnall HR, Measham F, Cole J. 2010. Analyses of second-generation 'legal highs' in the UK: initial findings. Drug Test Anal, 2 :377-382 >DOI >Link

Journal Articles

Mayer FP, Burchardt NV, Decker AM, Partilla JS, Li Y, McLaughlin G, Kavanagh PV, Sandtner W, Blough BE, Brandt SD, Baumann MH, Sitte HH. 2017. Fluorinated phenmetrazine "legal highs" act as substrates for high-affinity monoamine transporters of the SLC6 family Neuropharmacology, >DOI

Luethi D, Kaeser PJ, Brandt SD, Krähenbühl S, Hoener MC, Liechti ME. 2017. Pharmacological profile of methylphenidate-based designer drugs Neuropharmacology, >DOI

Brandt SD, Kavanagh PV, Twamley B, Westphal F, Elliott SP, Wallach J, Stratford A, Klein LM, Mccorvy JD, Nichols DE, Halberstadt AL. 2017. Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775) Drug Testing and Analysis, >DOI

Colestock T, Wallach J, Mansi M, Filemban N, Morris H, Elliott SP, Westphal F, Brandt SD, Adejare A. 2017. Syntheses, analytical and pharmacological characterizations of the 'legal high' 4-[1-(3-methoxyphenyl)cyclohexyl]morpholine (3-MeO-PCMo) and analogues Drug Testing and Analysis, >DOI

Huestis MA, Brandt SD, Rana S, Auaewrter V, Baumann MH. 2017. Impact of Novel Psychoactive Substances on Clinical and Forensic Toxicology and Global Public Health CLINICAL CHEMISTRY, 63 :1564-1569 >DOI >Link

Texter KB, Waymach R, Kavanagh PV, O'Brien JE, Talbot B, Brandt SD, Gardner EA. 2017. Identification of pyrolysis products of the new psychoactive substance 2-amino-1-(4-bromo-2,5-dimethoxyphenyl)ethanone hydrochloride (bk-2C-B) and its iodo analogue bk-2C-I Drug Testing and Analysis, >DOI

Wallach JV, Morris H, Brandt SD. 2017. Is nitrogen mustard contamination responsible for the reported MT-45 toxicity? BRITISH JOURNAL OF DERMATOLOGY, 177 :594-595 >DOI >Link

Caspar AT, Gaab JB, Michely JA, Brandt SD, Meyer MR, Maurer HH. 2017. Metabolism of the tryptamine-derived new psychoactive substances 5-MeO-2-Me-DALT, 5-MeO-2-Me-ALCHT, and 5-MeO-2-Me-DIPT and their detectability in urine studied by GC-MS, LC-MSn, and LC-HR-MS/MS Drug Testing and Analysis, >DOI

Brandt SD, Kavanagh PV, Westphal F, Elliott SP, Wallach J, Stratford A, Nichols DE, Halberstadt AL. 2017. Return of the lysergamides. Part III: Analytical characterization of N-6-ethyl-6-norlysergic acid diethylamide (ETH-LAD) and 1-propionyl ETH-LAD (1P-ETH-LAD) DRUG TESTING AND ANALYSIS, 9 :1641-1649 >DOI >Link

Brunt TM, Atkinson AM, Nefau T, Martinez M, Lahaie E, Malzcewski A, Pazitny M, Belackova V, Brandt SD. 2017. Online test purchased new psychoactive substances in 5 different European countries: A snapshot study of chemical composition and price INTERNATIONAL JOURNAL OF DRUG POLICY, 44 :105-114 >DOI >Link

Power JD, Kavanagh P, McLaughlin G, Barry M, Dowling G, Brandt SD. 2017. 'APAAN in the neck' - A reflection on some novel impurities found in seized materials containing amphetamine in Ireland during routine forensic analysis DRUG TESTING AND ANALYSIS, 9 :966-976 >DOI >Link

Wagmann L, Brandt SD, Kavanagh PV, Maurer HH, Meyer MR. 2017. In vitro monoamine oxidase inhibition potential of alpha-methyltryptamine analog new psychoactive substances for assessing possible toxic risks TOXICOLOGY LETTERS, 272 :84-93 >DOI >Link

Shekar A, Aguilar JI, Galli G, Cozzi NV, Brandt SD, Ruoho AE, Baumann MH, Matthies HJG, Galli A. 2017. Atypical dopamine efflux caused by 3,4-methylenedioxypyrovalerone (MDPV) via the human dopamine transporter JOURNAL OF CHEMICAL NEUROANATOMY, 83 :69-74 >DOI >Link

McLaughlin G, Morris N, Kavanagh PV, Power JD, Dowling G, Twamley B, O'Brien J, Hessman G, Murphy B, Walther D, Partilla JS, Baumann MH, Brandt SD. 2017. Analytical characterization and pharmacological evaluation of the new psychoactive substance 4-fluoromethylphenidate (4F-MPH) and differentiation between the (±)-threo and (±)-erythro diastereomers Drug Testing and Analysis, 9 :347-357 >DOI

Klare H, Neudoerfl JM, Brandt SD, Mischler E, Meier-Giebing S, Deluweit K, Westphal F, Laussmann T. 2017. Analysis of six 'neuro-enhancing' phenidate analogs DRUG TESTING AND ANALYSIS, 9 :423-435 >DOI >Link

Michely JA, Brandt SD, Meyer MR, Maurer HH. 2017. Biotransformation and detectability of the new psychoactive substances N,N-diallyltryptamine (DALT) derivatives 5-fluoro-DALT, 7-methyl-DALT, and 5,6-methylenedioxy-DALT in urine using GC-MS, LC-MSn, and LC-HR-MS/MS ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409 :1681-1695 >DOI >Link

Caspar AT, Brandt SD, Stoever AE, Meyer MR, Maurer HH. 2017. Metabolic fate and detectability of the new psychoactive substances 2-(4-bromo-2,5-dimethoxypheny1)-N-[(2-methoxyphenyl)methyl]ethanamine (25B-NBOMe) and 2-(4-chloro-2,5-dimethoxypheny1)-N-[(2-methoxyphenyl)methyl]ethanamine (25C-NBOMe) in human and rat urine by GC-MS, LC-MSn, and LC-HR-MS/MS approaches JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 134 :158-169 >DOI >Link

Michely JA, Manier SK, Caspar AT, Brandt SD, Wallach J, Maurer HH. 2017. New Psychoactive Substances 3-Methoxyphencyclidine (3-MeO-PCP) and 3-Methoxyrolicyclidine (3-MeO-PCPy): Metabolic Fate Elucidated with Rat Urine and Human Liver Preparations and their Detectability in Urine by GC-MS, "LC-(High Resolution)-MSn" and "LC-(High Resolution)-MS/MS" CURRENT NEUROPHARMACOLOGY, 15 :692-712 >DOI >Link

McLaughlin G, Morris N, Kavanagh PV, Power JD, Dowling G, Twamley B, O'Brien J, Talbot B, Walther D, Partilla JS, Baumann MH, Brandt SD. 2017. Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone. Drug Test Anal, 9 :358-368 >DOI >Link

Kang H, Park P, Bortolotto ZA, Brandt SD, Colestock T, Wallach J, Collingridge GL, Lodge D. 2017. Ephenidine: A new psychoactive agent with ketamine-like NMDA receptor antagonist properties. Neuropharmacology, 112 :144-149 >DOI >Link

Brandt SD, Kavanagh PV, Westphal F, Elliott SP, Wallach J, Colestock T, Burrow TE, Chapman SJ, Stratford A, Nichols DE, Halberstadt AL. 2017. Return of the lysergamides. Part II: Analytical and behavioural characterization of N6 -allyl-6-norlysergic acid diethylamide (AL-LAD) and (2'S,4'S)-lysergic acid 2,4-dimethylazetidide (LSZ). Drug Test Anal, 9 :38-50 >DOI >Link

Brandt SD, Kavanagh PV, Dowling G, Talbot B, Westphal F, Meyer MR, Maurer HH, Halberstadt AL. 2017. Analytical characterization of N,N-diallyltryptamine (DALT) and 16 ring-substituted derivatives. Drug Test Anal, 9 :115-126 >DOI >Link

Power J, Kavanagh P, McLaughlin G, Dowling G, Barry M, OBrien J, Talbot B, Twamley B, Brandt S. 2017. Forensic analysis of P2P derived amphetamine synthesis impurities: identification and characterization of indene by-products DRUG TESTING AND ANALYSIS, 9 :446-452 >DOI >Link

Cohen PA, Venhuis BJ, Brandt SD. 2016. Advancing supplement science: challenges and solutions Drug testing and analysis, 8

Dowling G, Kavanagh PV, Talbot B, O’Brien J, Hessman G, McLaughlin G, Twamley B, Brandt SD. 2016. Outsmarted by nootropics? An investigation into the thermal degradation of modafinil, modafinic acid, adrafinil, CRL-40,940 and CRL-40,941 in the GC injector: formation of 1,1,2,2-tetraphenylethane and its tetra fluoro analog. Drug Testing and Analysis, >DOI

Wallach J, Kang H, Colestock T, Morris H, Bortolotto ZA, Collingridge GL, Lodge D, Halberstadt AL, Brandt SD, Adejare A. 2016. Pharmacological investigations of the dissociative ‘Legal Highs’ diphenidine, methoxphenidine and analogues PLoS One, 11 :e0157021-e0157021 >DOI

Elliott SP, Brandt SD, Smith C. 2016. The first reported fatality associated with the synthetic opioid 3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide (U-47700) and implications for forensic analysis Drug Testing and Analysis, >DOI

Franz F, Angerer V, Brandt SD, McLaughlin G, Kavanagh PV, Moosmann B, Auwärter V. 2016. In vitro metabolism of the synthetic cannabinoid 3,5-AB-CHMFUPPYCA and its 5,3-regioisomer and investigation of their thermal stability Drug Testing and Analysis, 9 :311-316 >DOI

Cohen PA, Venhuis BJ, Brandt SD. 2016. Advancing supplement science: challenges and solutions Drug Testing and Analysis, 8 :e1-e3 >DOI

McLaughlin G, Morris N, Kavanagh PV, Dowling G, Power JD, Twamley B, O'Brien J, Talbot B, Sitte HH, Brandt SD. 2016. Test purchase, synthesis and characterization of 3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and para-substituted isomers Drug Testing and Analysis, >DOI

Dinger J, Woods C, Brandt SD, Meyer MR, Maurer HH. 2016. Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class Toxicology Letters, 241 :82-94 >DOI

Brandt SD, Kavanagh PV, Westphal F, Stratford A, Elliott SP, Hoang K, Wallach J, Halberstadt AL. 2016. Return of the lysergamides. Part I: Analytical and behavioural characterization of 1-propionyl-d-lysergic acid diethylamide (1P-LSD). Drug Test Anal, 8 :891-902 >DOI >Link

Marusich JA, Antonazzo KR, Blough BE, Brandt SD, Kavanagh PV, Partilla JS, Baumann MH. 2016. The new psychoactive substances 5-(2-aminopropyl)indole (5-IT) and 6-(2-aminopropyl)indole (6-IT) interact with monoamine transporters in brain tissue NEUROPHARMACOLOGY, 101 :68-75 >DOI >Link

McLaughlin G, Morris N, Kavanagh PV, Power JD, Twamley B, O'Brien J, Talbot B, Dowling G, Brandt SD. 2016. The synthesis and characterization of the 'research chemical' N-(1-amino-3-methyl-1oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide(3,5-AB-CHMFUPPYCA) and differentiation from its 5,3-regioisomer DRUG TESTING AND ANALYSIS, 8 :920-929 >DOI >Link

Wallach J, Colestock T, Cicali B, Elliott SP, Kavanagh PV, Adejare A, Dempster NM, Brandt SD. 2016. Syntheses and analytical characterizations of N-alkyl-arylcyclohexylamines DRUG TESTING AND ANALYSIS, 8 :801-815 >DOI >Link

Schindler CW, Thorndike EB, Goldberg SR, Lehner KR, Cozzi NV, Brandt SD, Baumann MH. 2016. Reinforcing and neurochemical effects of the "bath salts" constituents 3,4-methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxy-N-methylcathinone (methylone) in male rats. Psychopharmacology, 10 :1981-1990 >DOI

McLaughlin G, Morris N, Kavanagh PV, Power JD, O'Brien J, Talbot B, Elliott SP, Wallach J, Hoang K, Morris H, Brandt SD. 2016. Test purchase, synthesis, and characterization of 2-methoxydiphenidine (MXP) and differentiation from its meta- and para-substituted isomers Drug Testing and Analysis, 8 :98-109 >DOI

Michely JA, Helfer AG, Brandt SD, Meyer MR, Maurer HH. 2015. Metabolism of the new psychoactive substances N,N-diallyltryptamine (DALT) and 5-methoxy-DALT and their detectability in urine by GC–MS, LC–MS n , and LC–HR–MS–MS Analytical and Bioanalytical Chemistry, 407 :7831-7842 >DOI

Caspar AT, Helfer AG, Michely JA, Auwärter V, Brandt SD, Meyer MR, Maurer HH. 2015. Studies on the metabolism and toxicological detection of the new psychoactive designer drug 2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOMe) in human and rat urine using GC-MS, LC-MSn, and LC-HR-MS/MS Analytical and Bioanalytical Chemistry, 407 :6697-6719 >DOI

Wallach J, Kavanagh PV, Mclaughlin G, Morris N, Power JD, Elliott SP, Mercier MS, Lodge D, Morris H, Dempster NM, Brandt SD. 2015. Preparation and characterization of the 'research chemical' diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers Drug Testing and Analysis, 7 :358-367 >DOI

Power JD, Kavanagh P, McLaughlin G, O'Brien J, Talbot B, Barry M, Twamley B, Dowling G, Brandt SD. 2015. Identification and characterization of an imidazolium by-product formed during the synthesis of 4-methylmethcathinone (mephedrone) Drug Testing and Analysis, 7 :894-902 >DOI

Brandt SD, Elliott SP, Kavanagh PV, Dempster NM, Meyer MR, Maurer HH, Nichols DE. 2015. Analytical characterization of bioactive N-benzyl-substituted phenethylamines and 5-methoxytryptamines Rapid Communications in Mass Spectrometry, 29 :573-584 >DOI

Welter J, Brandt SD, Kavanagh P, Meyer MR, Maurer HH. 2015. Metabolic fate, mass spectral fragmentation, detectability, and differentiation in urine of the benzofuran designer drugs 6-APB and 6-MAPB in comparison to their 5-isomers using GC-MS and LC-(HR)-MSn techniques Analytical and Bioanalytical Chemistry, 407 :3457-3470 >DOI

Elliott SP, Brandt SD, Wallach J, Morris H, Kavanagh PV. 2015. First Reported Fatalities Associated with the 'Research Chemical' 2-Methoxydiphenidine Journal of Analytical Toxicology, 39 :287-293 >DOI

Nichols DE, Sassano MF, Halberstadt AL, Klein LM, Brandt SD, Elliott SP, Fiedler WJ. 2015. N -Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT<inf>2</inf> Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues ACS Chemical Neuroscience, 6 :1165-1175 >DOI

McLaughlin G, Morris N, Kavanagh PV, Power JD, Twamley B, O'Brien J, Talbot B, Dowling G, Mahony O, Brandt SD, Patrick J, Archer RP, Partilla JS, Baumann MH. 2015. Synthesis, characterization, and monoamine transporter activity of the new psychoactive substance 3′,4′-methylenedioxy-4-methylaminorex (MDMAR) Drug Testing and Analysis, 7 :555-564 >DOI

Power JD, Kavanagh P, O'Brien J, Barry M, Twamley B, Talbot B, Dowling G, Brandt SD. 2015. Test purchase, identification and synthesis of 2-amino-1-(4-bromo-2, 5-dimethoxyphenyl)ethan-1-one (bk-2C-B) Drug Testing and Analysis, 7 :512-518 >DOI

Brandt SD, King LA, Evans-Brown M. 2014. The new drug phenomenon Brandt SD. Drug Testing and Analysis, 6 :587-597 >DOI

Brandt SD, Baumann MH, Partilla JS, Kavanagh PV, Power JD, Talbot B, Twamley B, Mahony O, O'Brien J, Elliott SP, Archer RP, Patrick J, Singh K, Dempster NM, Cosbey SH. 2014. Characterization of a novel and potentially lethal designer drug (±)-cis-para -methyl-4-methylaminorex (4,4'-DMAR, or ‘Serotoni’) Brandt SD. Drug Testing and Analysis, 6 :684-695 >DOI

Cosbey S, Kirk S, McNaul M, Peters L, Prentice B, Quinn A, Elliott S, Brandt S, Archer R. 2014. Multiple Fatalities Involving a New Designer Drug: Para-Methyl-4-Methylaminorex Journal of Analytical Toxicology, 38 :383-384 >DOI

Nasomjai P, Arpha K, Sodngam S, Brandt SD. 2014. Potential antimalarial derivatives from astraodorol Archives of Pharmacal Research, 37 :1538-1545 >DOI

Evans-Brown M, Kimergard A, McVeigh J, Chandler M, Brandt SD. 2014. BODYBUILDING SUPPLEMENTS Is the breast cancer drug tamoxifen being sold as a bodybuilding dietary supplement? BMJ-BRITISH MEDICAL JOURNAL, 348 >DOI >Link

Meyer MR, Caspar A, Brandt SD, Maurer HH. 2014. A qualitative/quantitative approach for the detection of 37 tryptamine-derived designer drugs, 5 β-carbolines, ibogaine, and yohimbine in human urine and plasma using standard urine screening and multi-analyte approaches Analytical and Bioanalytical Chemistry, 406 :225-237 >DOI

Herraiz T, Brandt SD. 2014. 5-(2-Aminopropyl)indole (5-IT): a psychoactive substance used for recreational purposes is an inhibitor of human monoamine oxidase (MAO) Brandt SD. Drug Testing and Analysis, 6 :607-613 >DOI

King LA, Ujváry I, Brandt SD. 2014. Drug laws and the 'derivative' problem Brandt SD. Drug Testing and Analysis, 6 :879-883 >DOI

Gaujac A, Dempster N, Navickiene S, Brandt SD, Andrade JBD. 2013. Determination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometry Talanta, 106 :394-398 >DOI

Wallach J, Adejare A, Paoli GD, Brandt SD. 2013. Preparation and analytical characterization of 1-(1-phenylcyclohexyl)piperidine (PCP) and 1-(1-phenylcyclohexyl)pyrrolidine (PCPy) analogues Drug Testing and Analysis, >DOI

Kanu AB, Brandt SD, Williams MD, Zhang N, Hill HH. 2013. Analysis of psychoactive cathinones and tryptamines by electrospray ionization atmospheric pressure ion mobility time-of-flight mass spectrometry Analytical Chemistry, 85 :8535-8542 >DOI

De Paoli G, Brandt SD, Wallach J, Archer RP, Pounder DJ. 2013. From the Street to the Laboratory: Analytical Profiles of Methoxetamine, 3-Methoxyeticyclidine and 3-Methoxyphencyclidine and their Determination in Three Biological Matrices Journal of Analytical Toxicology, 37 :277-283 >DOI

Gaujac A, Ford JL, Dempster NM, de Andrade JB, Brandt SD. 2013. Investigations into the polymorphic properties of N,N-dimethyltryptamine by X-ray diffraction and differential scanning calorimetry Microchemical Journal, 110 :146-157 >DOI

Elliott SP, Brandt SD, Freeman S, Archer RP. 2013. AMT (3-(2-aminopropyl)indole) and 5-IT (5-(2-aminopropyl)indole): An analytical challenge and implications for forensic analysis Drug Testing and Analysis, 5 :196-202 >DOI

Baumann MH, Partilla JS, Lehner KR, Thorndike EB, Hoffman AF, Holy M, Rothman RB, Goldberg SR, Lupica CR, Sitte HH, Brandt SD, Tella SR, Cozzi NV, Schindler CW. 2013. Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive ‘Bath Salts’ Products Neuropsychopharmacology, 38 :552-562 >DOI

Cozzi NV, Brandt SD, Daley PF, Partilla JS, Rothman RB, Tulzer A, Sitte HH, Baumann MH. 2013. Pharmacological examination of trifluoromethyl ring-substituted methcathinone analogs European Journal of Pharmacology, 699 :180-187 >DOI

Gaujac A, Navickiene S, Collins MI, Brandt SD, de Andrade JB. 2012. Analytical techniques for the determination of tryptamines and β-carbolines in plant matrices and in psychoactive beverages consumed during religious ceremonies and neo-shamanic urban practices. Drug testing and analysis, 4 :636-648

Passie T, Emrich HM, Karst M, Brandt SD, Halpern JH. 2012. Mitigation of post-traumatic stress symptoms by Cannabis resin: a review of the clinical and neurobiological evidence. Drug testing and analysis, 4 :649-659

Brandt SD, Passie T. 2012. Research on psychedelic substances. Drug testing and analysis, 4 :539-542

Passie T, Emrich HM, Karst M, Brandt SD, Halpern JH. 2012. Mitigation of post-traumatic stress symptoms by Cannabis resin: a review of the clinical and neurobiological evidence. Drug testing and analysis, 4 :649-659

Gaujac A, Navickiene S, Collins MI, Brandt SD, de Andrade JB. 2012. Analytical techniques for the determination of tryptamines and β-carbolines in plant matrices and in psychoactive beverages consumed during religious ceremonies and neo-shamanic urban practices. Drug testing and analysis, 4 :636-648

Passie T, Emrich HM, Karst M, Brandt SD, Halpern JH. 2012. Mitigation of post-traumatic stress symptoms by Cannabis resin: A review of the clinical and neurobiological evidence Brandt SD, Passie T. Drug Testing and Analysis, 4 :649-659 >DOI

Brandt SD, Passie T. 2012. Research on psychedelic substances Brandt SD, Passie T. Drug Testing and Analysis, 4 :539-542 >DOI

Gaujac A, Navickiene S, Collins MI, Brandt SD, Andrade JB. 2012. Analytical techniques for the determination of tryptamines and β-carbolines in plant matrices and in psychoactive beverages consumed during religious ceremonies and neo-shamanic urban practices Brandt SD, Passie T. Drug Testing and Analysis, 4 :636-648 >DOI

Baumann MH, Ayestas MA, Partilla JS, Sink JR, Shulgin AT, Daley PF, Brandt SD, Rothman RB, Ruoho AE, Cozzi NV. 2012. The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue Neuropsychopharmacology, 37 :1192-1203 >DOI

Brandt SD, Daley PF, Cozzi NV. 2012. Analytical characterization of three trifluoromethyl-substituted methcathinone isomers Drug Testing and Analysis, 4 :525-529 >DOI

Brandt SD, Tearavarich R, Dempster N, Cozzi NV, Daley PF. 2012. Synthesis and characterization of 5-methoxy-2-methyl-N,N-dialkylated tryptamines Drug Testing and Analysis, 4 :24-32 >DOI

De Paoli G, Brandt SD, Pounder DJ. 2011. Analytical characterization and rapid determination of 2-(diphenylmethyl)pyrrolidine in blood and application to an internet product Journal of Chromatography B, 879 :3771-3774 >DOI

Brandt SD, Freeman S, Sumnall HR, Measham F, Cole J. 2011. Analysis of NRG 'legal highs' in the UK: identification and formation of novel cathinones. Drug testing and analysis, 3 :569-575

Brandt SD. 2011. Special issue on illicit drugs Brandt SD. Drug Testing and Analysis, 3 :525-526 >DOI

De Paoli G, Brandt SD, Pounder DJ. 2011. Mephedrone. Banned but still available on the internet. BMJ, 342 :d1629 >Link

Sumnall H, Measham F, Brandt S, Cole J. 2011. Salvia divinorum use and phenomenology: results from an online survey Journal of Psychopharmacology, 25 :1496-1507 >DOI

Brandt SD, Sumnall HR, Measham F, Cole J. 2010. Analyses of second-generation 'legal highs' in the UK: initial findings. Drug Test Anal, 2 :377-382 >DOI >Link

Brandt SD, Martins CPB. 2010. Analytical methods for psychoactive N,N-dialkylated tryptamines TRAC-TREND ANAL CHEM, 29 :858-869 >DOI

Brandt SD, Wootton RCR, De Paoli G, Freeman S. 2010. The naphyrone story: The Alpha or Beta-naphthyl Isomer? Drug Testing and Analysis, 2 :496-502 >DOI

Brandt SD, Sumnall HR, Measham F, Cole J. 2010. Second generation mephedrone The confusing case of NRG-1 BRITISH MEDICAL JOURNAL, 341 >DOI >Link

Brandt SD, Moore SA, Freeman S, Kanu AB. 2010. Characterization of the synthesis of N,N-dimethyltryptamine by reductive amination using gas chromatography ion trap mass spectrometry. Drug Test Anal, 2 :330-338 >DOI >Link

Martins CP, Freeman S, Alder JF, Passie T, Brandt SD. 2010. Profiling psychoactive tryptamine-drug synthesis by focusing on detection using mass spectrometry TrAC Trends in Analytical Chemistry, 29 :285-296 >DOI

Kanu AB, Hampikian G, Brandt SD, Hill HH. 2010. Ribonucleotide and ribonucleoside determination by ambient pressure ion mobility spectrometry Analytica Chimica Acta, 658 :91-97 >DOI

Wainwright M, Brandt SD, Smith A, Styles A, Meegan K, Loughran C. 2010. Phenothiazinium photosensitisers VII: Novel substituted asymmetric N-benzylphenothiaziniums as photoantimicrobial agents Journal of Photochemistry and Photobiology B: Biology, 99 :74-77 >DOI

Martins CP, Freeman S, Alder JF, Brandt SD. 2009. Characterisation of a proposed internet synthesis of N,N-dimethyltryptamine using liquid chromatography/electrospray ionisation tandem mass spectrometry Journal of Chromatography A, 1216 :6119-6123 >DOI

Mansell D, Brandt SD, Nasima S, Turvey N, Alder JF, Freeman S, Schwalbe CH. 2009. Conformational Evaluation of Indol-3-yl- N -alkyl-glyoxalylamides and Indol-3-yl- N,N -dialkyl-glyoxalylamides Spectroscopy Letters, 42 :156-166 >DOI

Brandt SD, Tirunarayanapuram SS, Freeman S, Dempster N, Barker SA, Daley PF, Cozzi NV, Martins CPB. 2008. Microwave-accelerated synthesis of psychoactive deuterated N,N-dialkylated-[α,α,β,β-d4]-tryptamines Journal of Labelled Compounds and Radiopharmaceuticals, 51 :423-429 >DOI

Martins CP, Awan MA, Freeman S, Herraiz T, Alder JF, Brandt SD. 2008. Fingerprint analysis of thermolytic decarboxylation of tryptophan to tryptamine catalyzed by natural oils Journal of Chromatography A, 1210 :115-120 >DOI

Zainoor NM, Wainwright M, Dyas AM, Rostron C, Brandt S. 2008. An evaluation of the chemotaxonomy of Lignosus rhinocerus JOURNAL OF PHARMACY AND PHARMACOLOGY, 60 :A4-A5 >Link

Guy M, Freeman S, Alder J, Brandt S. 2008. The Henry reaction: spectroscopic studies of nitrile and hydroxylamine by-products formed during synthesis of psychoactive phenylalkylamines Open Chemistry, 6 >DOI

Brandt SD, Martins CP, Freeman S, Dempster N, Riby PG, Gartz J, Alder JF. 2008. Halogenated solvent interactions with N,N-dimethyltryptamine: Formation of quaternary ammonium salts and their artificially induced rearrangements during analysis Forensic Science International, 178 :162-170 >DOI

Brandt SD, Martins CP, Freeman S, Dempster N, Wainwright M, Riby PG, Alder JF. 2008. N,N-Dimethyltryptamine and dichloromethane: Rearrangement of quaternary ammonium salt product during GC–EI and CI-MS–MS analysis Journal of Pharmaceutical and Biomedical Analysis, 47 :207-212 >DOI

Schwalbe CH, Nasima S, Freeman S, Mansell D, Brandt SD, Alder JF. 2007. Molecular and supramolecular features of glyoxylamides Acta Crystallographica Section A, 63 :A197-A198

Zainoor NM, Wainwright M, Rostron C, Brandt S. 2007. Distribution of ergosterol in different parts of Lignosus rhinocerus JOURNAL OF PHARMACY AND PHARMACOLOGY, 59 :A59-A60 >Link

Brandt SD, Mansell D, Freeman S, Fleet IA, Alder JF. 2006. Analytical characterisation of the routes by thermolytic decarboxylation from tryptophan to tryptamine using ketone catalysts, resulting in tetrahydro-β-carboline formation Journal of Pharmaceutical and Biomedical Analysis, 41 :872-882 >DOI

Brandt SD, Freeman S, Fleet IA, Alder JF. 2005. Analytical chemistry of synthetic routes to psychoactive tryptamines : Part III. Characterisation of the Speeter and Anthony route to N,N-dialkylated tryptamines using CI-IT-MS-MS The Analyst, 130 :1258-1258 >DOI

Brandt SD, Freeman S, Fleet IA, McGagh P, Alder JF. 2005. Analytical chemistry of synthetic routes to psychoactive tryptamines : Part II. Characterisation of the Speeter and Anthony synthetic route to N,N-dialkylated tryptamines using GC-EI-ITMS, ESI-TQ-MS-MS and NMR The Analyst, 130 :330-330 >DOI

Brandt SD, Freeman S, McGagh P, Abdul-Halim N, Alder JF. 2004. An analytical perspective on favoured synthetic routes to the psychoactive tryptamines Journal of Pharmaceutical and Biomedical Analysis, 36 :675-691 >DOI

Brandt SD, Freeman S, Fleet IA, McGagh P, Alder JF. 2004. Analytical chemistry of synthetic routes to psychoactive tryptamines : Part I. Characterisation of the Speeter and Anthony synthetic route to 5-methoxy-N,N-diisopropyltryptamine using ESI-MS-MS and ESI-TOF-MS The Analyst, 129 :1047-1047 >DOI

Editorials and letter to the editor

Brandt SD, Kavanagh PV. 2017. Addressing the challenges in forensic drug chemistry DRUG TESTING AND ANALYSIS, 9 :342-346 >DOI >Link

Chapters

Brandt SD, Braithwaite RA, Evans-Brown M, Kicman AT. 2013. Aminoindane Analogues Dargan PI, Wood DM. Novel Psychoactive Substances. Classification, Pharmacology and Toxicology :261-283 Academic Press 978-0124158160

Brandt SD. 2011. CNS stimulants and CNS-active drugs affecting the serotonergic system Watson DG. Pharmaceutical Chemistry :347-387 9780443072321