Liverpool Skylilne

Pharmacy and Biomolecular Sciences

Dr Steven Enoch

Dr Steven Enoch

Telephone: 0151 231 2164

Publications

Journal article

Cronin MTD, Enoch SJ, Hewitt M, Madden JC. 2011. Formation of mechanistic categories and local models to facilitate the prediction of toxicity. ALTEX, 28 :45-49 >DOI

Schwöbel JAH, Koleva YK, Enoch SJ, Bajot F, Hewitt M, Madden JC, Roberts DW, Schultz TW, Cronin MTD. 2011. Measurement and estimation of electrophilic reactivity for predictive toxicology. Chem Rev, 111 :2562-2596 >DOI >Link

Ellison CM, Sherhod R, Cronin MTD, Enoch SJ, Madden JC, Judson PN. 2011. Assessment of methods to define the applicability domain of structural alert models. J Chem Inf Model, 51 :975-985 >DOI >Link

Cronin MTD, Enoch SJ, Hewitt M, Madden JC. 2011. Formation of mechanistic categories and local models to facilitate the prediction of toxicity. ALTEX, 28 :45-49 >DOI

Schwöbel JAH, Koleva YK, Enoch SJ, Bajot F, Hewitt M, Madden JC, Roberts DW, Schultz TW, Cronin MTD. 2011. Measurement and estimation of electrophilic reactivity for predictive toxicology. Chem Rev, 111 :2562-2596 >DOI >Link

Ellison CM, Sherhod R, Cronin MTD, Enoch SJ, Madden JC, Judson PN. 2011. Assessment of methods to define the applicability domain of structural alert models. J Chem Inf Model, 51 :975-985 >DOI >Link

Cronin MTD, Enoch SJ, Hewitt M, Madden JC. 2011. Formation of mechanistic categories and local models to facilitate the prediction of toxicity. ALTEX, 28 :45-49 >DOI

Schwöbel JAH, Koleva YK, Enoch SJ, Bajot F, Hewitt M, Madden JC, Roberts DW, Schultz TW, Cronin MTD. 2011. Measurement and estimation of electrophilic reactivity for predictive toxicology. Chem Rev, 111 :2562-2596 >DOI >Link

Ellison CM, Sherhod R, Cronin MTD, Enoch SJ, Madden JC, Judson PN. 2011. Assessment of methods to define the applicability domain of structural alert models. J Chem Inf Model, 51 :975-985 >DOI >Link

Cronin MTD, Enoch SJ, Hewitt M, Madden JC. 2011. Formation of mechanistic categories and local models to facilitate the prediction of toxicity. ALTEX, 28 :45-49 >DOI

Schwöbel JAH, Koleva YK, Enoch SJ, Bajot F, Hewitt M, Madden JC, Roberts DW, Schultz TW, Cronin MTD. 2011. Measurement and estimation of electrophilic reactivity for predictive toxicology. Chem Rev, 111 :2562-2596 >DOI >Link

Ellison CM, Sherhod R, Cronin MTD, Enoch SJ, Madden JC, Judson PN. 2011. Assessment of methods to define the applicability domain of structural alert models. J Chem Inf Model, 51 :975-985 >DOI >Link

Hewitt M, Ellison CM, Enoch SJ, Madden JC, Cronin MTD. 2010. Integrating (Q)SAR models, expert systems and read-across approaches for the prediction of developmental toxicity. Reprod Toxicol, 30 :147-160 >DOI >Link

Enoch SJ, Roberts DW, Cronin MTD. 2010. Mechanistic category formation for the prediction of respiratory sensitization. Chem Res Toxicol, 23 :1547-1555 >DOI >Link

Enoch SJ, Cronin MTD. 2010. A review of the electrophilic reaction chemistry involved in covalent DNA binding. Crit Rev Toxicol, 40 :728-748 >DOI >Link

Hewitt M, Ellison CM, Enoch SJ, Madden JC, Cronin MTD. 2010. Integrating (Q)SAR models, expert systems and read-across approaches for the prediction of developmental toxicity. Reprod Toxicol, 30 :147-160 >DOI >Link

Enoch SJ, Roberts DW, Cronin MTD. 2010. Mechanistic category formation for the prediction of respiratory sensitization. Chem Res Toxicol, 23 :1547-1555 >DOI >Link

Enoch SJ, Cronin MTD. 2010. A review of the electrophilic reaction chemistry involved in covalent DNA binding. Crit Rev Toxicol, 40 :728-748 >DOI >Link

Hewitt M, Ellison CM, Enoch SJ, Madden JC, Cronin MTD. 2010. Integrating (Q)SAR models, expert systems and read-across approaches for the prediction of developmental toxicity. Reprod Toxicol, 30 :147-160 >DOI >Link

Enoch SJ, Roberts DW, Cronin MTD. 2010. Mechanistic category formation for the prediction of respiratory sensitization. Chem Res Toxicol, 23 :1547-1555 >DOI >Link

Enoch SJ, Cronin MTD. 2010. A review of the electrophilic reaction chemistry involved in covalent DNA binding. Crit Rev Toxicol, 40 :728-748 >DOI >Link

Hewitt M, Ellison CM, Enoch SJ, Madden JC, Cronin MTD. 2010. Integrating (Q)SAR models, expert systems and read-across approaches for the prediction of developmental toxicity. Reprod Toxicol, 30 :147-160 >DOI >Link

Enoch SJ, Roberts DW, Cronin MTD. 2010. Mechanistic category formation for the prediction of respiratory sensitization. Chem Res Toxicol, 23 :1547-1555 >DOI >Link

Enoch SJ, Cronin MTD. 2010. A review of the electrophilic reaction chemistry involved in covalent DNA binding. Crit Rev Toxicol, 40 :728-748 >DOI >Link

Jomova K, Kysel O, Madden JC, Morris H, Enoch SJ, Budzak S, Young AJ, Cronin MTD, Mazur M, Valko M. 2009. Electron transfer from all-trans beta-carotene to the t-butyl peroxyl radical at low oxygen pressure (an EPR spectroscopy and computational study) CHEMICAL PHYSICS LETTERS, 478 :266-270 >DOI >Link

Madden JC, Enoch SJ, Hewitt M, Cronin MTD. 2009. Pharmaceuticals in the environment: good practice in predicting acute ecotoxicological effects. Toxicol Lett, 185 :85-101 >DOI >Link

Enoch SJ, Roberts DW, Cronin MTD. 2009. Electrophilic reaction chemistry of low molecular weight respiratory sensitizers. Chem Res Toxicol, 22 :1447-1453 >DOI >Link

Hewitt M, Cronin MTD, Enoch SJ, Madden JC, Roberts DW, Dearden JC. 2009. In silico prediction of aqueous solubility: the solubility challenge. J Chem Inf Model, 49 :2572-2587 >DOI >Link

Cronin MTD, Bajot F, Enoch SJ, Madden JC, Roberts DW, Schwöbel J. 2009. The in chemico-in silico interface: challenges for integrating experimental and computational chemistry to identify toxicity. Altern Lab Anim, 37 :513-521 >DOI >Link

Ellison CM, Enoch SJ, Cronin MT, Madden JC, Judson P. 2009. Definition of the applicability domains of knowledge-based predictive toxicology expert systems by using a structural fragment-based approach. Altern Lab Anim, 37 :533-545 >DOI >Link

Enoch SJ, Cronin MTD, Madden JC, Hewitt M. 2009. Formation of Structural Categories to Allow for Read-Across for Teratogenicity QSAR & COMBINATORIAL SCIENCE, 28 :696-708 >DOI >Link

Aptula AO, Enoch SJ, Roberts DW. 2009. Chemical Mechanisms for Skin Sensitization by Aromatic Compounds with Hydroxy and Amino Groups CHEMICAL RESEARCH IN TOXICOLOGY, 22 :1541-1547 >DOI >Link

Jomova K, Kysel O, Madden JC, Morris H, Enoch SJ, Budzak S, Young AJ, Cronin MTD, Mazur M, Valko M. 2009. Electron transfer from all-trans beta-carotene to the t-butyl peroxyl radical at low oxygen pressure (an EPR spectroscopy and computational study) CHEMICAL PHYSICS LETTERS, 478 :266-270 >DOI >Link

Madden JC, Enoch SJ, Hewitt M, Cronin MTD. 2009. Pharmaceuticals in the environment: good practice in predicting acute ecotoxicological effects. Toxicol Lett, 185 :85-101 >DOI >Link

Enoch SJ, Roberts DW, Cronin MTD. 2009. Electrophilic reaction chemistry of low molecular weight respiratory sensitizers. Chem Res Toxicol, 22 :1447-1453 >DOI >Link

Hewitt M, Cronin MTD, Enoch SJ, Madden JC, Roberts DW, Dearden JC. 2009. In silico prediction of aqueous solubility: the solubility challenge. J Chem Inf Model, 49 :2572-2587 >DOI >Link

Cronin MTD, Bajot F, Enoch SJ, Madden JC, Roberts DW, Schwöbel J. 2009. The in chemico-in silico interface: challenges for integrating experimental and computational chemistry to identify toxicity. Altern Lab Anim, 37 :513-521 >DOI >Link

Ellison CM, Enoch SJ, Cronin MT, Madden JC, Judson P. 2009. Definition of the applicability domains of knowledge-based predictive toxicology expert systems by using a structural fragment-based approach. Altern Lab Anim, 37 :533-545 >DOI >Link

Enoch SJ, Cronin MTD, Madden JC, Hewitt M. 2009. Formation of Structural Categories to Allow for Read-Across for Teratogenicity QSAR & COMBINATORIAL SCIENCE, 28 :696-708 >DOI >Link

Aptula AO, Enoch SJ, Roberts DW. 2009. Chemical Mechanisms for Skin Sensitization by Aromatic Compounds with Hydroxy and Amino Groups CHEMICAL RESEARCH IN TOXICOLOGY, 22 :1541-1547 >DOI >Link

Jomova K, Kysel O, Madden JC, Morris H, Enoch SJ, Budzak S, Young AJ, Cronin MTD, Mazur M, Valko M. 2009. Electron transfer from all-trans beta-carotene to the t-butyl peroxyl radical at low oxygen pressure (an EPR spectroscopy and computational study) CHEMICAL PHYSICS LETTERS, 478 :266-270 >DOI >Link

Madden JC, Enoch SJ, Hewitt M, Cronin MTD. 2009. Pharmaceuticals in the environment: good practice in predicting acute ecotoxicological effects. Toxicol Lett, 185 :85-101 >DOI >Link

Enoch SJ, Roberts DW, Cronin MTD. 2009. Electrophilic reaction chemistry of low molecular weight respiratory sensitizers. Chem Res Toxicol, 22 :1447-1453 >DOI >Link

Hewitt M, Cronin MTD, Enoch SJ, Madden JC, Roberts DW, Dearden JC. 2009. In silico prediction of aqueous solubility: the solubility challenge. J Chem Inf Model, 49 :2572-2587 >DOI >Link

Cronin MTD, Bajot F, Enoch SJ, Madden JC, Roberts DW, Schwöbel J. 2009. The in chemico-in silico interface: challenges for integrating experimental and computational chemistry to identify toxicity. Altern Lab Anim, 37 :513-521 >DOI >Link

Ellison CM, Enoch SJ, Cronin MT, Madden JC, Judson P. 2009. Definition of the applicability domains of knowledge-based predictive toxicology expert systems by using a structural fragment-based approach. Altern Lab Anim, 37 :533-545 >DOI >Link

Enoch SJ, Cronin MTD, Madden JC, Hewitt M. 2009. Formation of Structural Categories to Allow for Read-Across for Teratogenicity QSAR & COMBINATORIAL SCIENCE, 28 :696-708 >DOI >Link

Aptula AO, Enoch SJ, Roberts DW. 2009. Chemical Mechanisms for Skin Sensitization by Aromatic Compounds with Hydroxy and Amino Groups CHEMICAL RESEARCH IN TOXICOLOGY, 22 :1541-1547 >DOI >Link

Jomova K, Kysel O, Madden JC, Morris H, Enoch SJ, Budzak S, Young AJ, Cronin MTD, Mazur M, Valko M. 2009. Electron transfer from all-trans beta-carotene to the t-butyl peroxyl radical at low oxygen pressure (an EPR spectroscopy and computational study) CHEMICAL PHYSICS LETTERS, 478 :266-270 >DOI >Link

Madden JC, Enoch SJ, Hewitt M, Cronin MTD. 2009. Pharmaceuticals in the environment: good practice in predicting acute ecotoxicological effects. Toxicol Lett, 185 :85-101 >DOI >Link

Enoch SJ, Roberts DW, Cronin MTD. 2009. Electrophilic reaction chemistry of low molecular weight respiratory sensitizers. Chem Res Toxicol, 22 :1447-1453 >DOI >Link

Hewitt M, Cronin MTD, Enoch SJ, Madden JC, Roberts DW, Dearden JC. 2009. In silico prediction of aqueous solubility: the solubility challenge. J Chem Inf Model, 49 :2572-2587 >DOI >Link

Cronin MTD, Bajot F, Enoch SJ, Madden JC, Roberts DW, Schwöbel J. 2009. The in chemico-in silico interface: challenges for integrating experimental and computational chemistry to identify toxicity. Altern Lab Anim, 37 :513-521 >DOI >Link

Ellison CM, Enoch SJ, Cronin MT, Madden JC, Judson P. 2009. Definition of the applicability domains of knowledge-based predictive toxicology expert systems by using a structural fragment-based approach. Altern Lab Anim, 37 :533-545 >DOI >Link

Enoch SJ, Cronin MTD, Madden JC, Hewitt M. 2009. Formation of Structural Categories to Allow for Read-Across for Teratogenicity QSAR & COMBINATORIAL SCIENCE, 28 :696-708 >DOI >Link

Aptula AO, Enoch SJ, Roberts DW. 2009. Chemical Mechanisms for Skin Sensitization by Aromatic Compounds with Hydroxy and Amino Groups CHEMICAL RESEARCH IN TOXICOLOGY, 22 :1541-1547 >DOI >Link

Enoch SJ, Cronin MTD, Schultz TW, Madden JC. 2008. Quantitative and mechanistic read across for predicting the skin sensitization potential of alkenes acting via Michael addition. Chem Res Toxicol, 21 :513-520 >DOI >Link

Enoch SJ, Cronin MTD, Schultz TW, Madden JC. 2008. An evaluation of global QSAR models for the prediction of the toxicity of phenols to Tetrahymena pyriformis. Chemosphere, 71 :1225-1232 >DOI >Link

Enoch SJ, Hewitt M, Cronin MTD, Azam S, Madden JC. 2008. Classification of chemicals according to mechanism of aquatic toxicity: an evaluation of the implementation of the Verhaar scheme in Toxtree. Chemosphere, 73 :243-248 >DOI >Link

Enoch SJ, Madden JC, Cronin MTD. 2008. Identification of mechanisms of toxic action for skin sensitisation using a SMARTS pattern based approach. SAR QSAR Environ Res, 19 :555-578 >DOI >Link

Enoch SJ, Cronin MTD, Schultz TW, Madden JC. 2008. Quantitative and mechanistic read across for predicting the skin sensitization potential of alkenes acting via Michael addition. Chem Res Toxicol, 21 :513-520 >DOI >Link

Enoch SJ, Cronin MTD, Schultz TW, Madden JC. 2008. An evaluation of global QSAR models for the prediction of the toxicity of phenols to Tetrahymena pyriformis. Chemosphere, 71 :1225-1232 >DOI >Link

Enoch SJ, Hewitt M, Cronin MTD, Azam S, Madden JC. 2008. Classification of chemicals according to mechanism of aquatic toxicity: an evaluation of the implementation of the Verhaar scheme in Toxtree. Chemosphere, 73 :243-248 >DOI >Link

Enoch SJ, Madden JC, Cronin MTD. 2008. Identification of mechanisms of toxic action for skin sensitisation using a SMARTS pattern based approach. SAR QSAR Environ Res, 19 :555-578 >DOI >Link

Enoch SJ, Cronin MTD, Schultz TW, Madden JC. 2008. Quantitative and mechanistic read across for predicting the skin sensitization potential of alkenes acting via Michael addition. Chem Res Toxicol, 21 :513-520 >DOI >Link

Enoch SJ, Cronin MTD, Schultz TW, Madden JC. 2008. An evaluation of global QSAR models for the prediction of the toxicity of phenols to Tetrahymena pyriformis. Chemosphere, 71 :1225-1232 >DOI >Link

Enoch SJ, Hewitt M, Cronin MTD, Azam S, Madden JC. 2008. Classification of chemicals according to mechanism of aquatic toxicity: an evaluation of the implementation of the Verhaar scheme in Toxtree. Chemosphere, 73 :243-248 >DOI >Link

Enoch SJ, Madden JC, Cronin MTD. 2008. Identification of mechanisms of toxic action for skin sensitisation using a SMARTS pattern based approach. SAR QSAR Environ Res, 19 :555-578 >DOI >Link

Enoch SJ, Cronin MTD, Schultz TW, Madden JC. 2008. Quantitative and mechanistic read across for predicting the skin sensitization potential of alkenes acting via Michael addition. Chem Res Toxicol, 21 :513-520 >DOI >Link

Enoch SJ, Cronin MTD, Schultz TW, Madden JC. 2008. An evaluation of global QSAR models for the prediction of the toxicity of phenols to Tetrahymena pyriformis. Chemosphere, 71 :1225-1232 >DOI >Link

Enoch SJ, Hewitt M, Cronin MTD, Azam S, Madden JC. 2008. Classification of chemicals according to mechanism of aquatic toxicity: an evaluation of the implementation of the Verhaar scheme in Toxtree. Chemosphere, 73 :243-248 >DOI >Link

Enoch SJ, Madden JC, Cronin MTD. 2008. Identification of mechanisms of toxic action for skin sensitisation using a SMARTS pattern based approach. SAR QSAR Environ Res, 19 :555-578 >DOI >Link

Hewitt M, Cronin MTD, Madden JC, Rowe PH, Johnson C, Obi A, Enoch SJ. 2007. Consensus QSAR models: do the benefits outweigh the complexity? J Chem Inf Model, 47 :1460-1468 >DOI >Link

Hewitt M, Cronin MTD, Madden JC, Rowe PH, Enoch SJ. 2007. Applying consensus models to heterogeneous datasets - Any benefit over single MLR models? DRUGS OF THE FUTURE, 32 :90-90 >Link

Hewitt M, Azam S, Enoch SJ, Madden JC, Cronin MTD. 2007. Prioritising chemicals for testing: Risk assessment based on predicted mechanism of toxic action DRUGS OF THE FUTURE, 32 :112-113 >Link

Hewitt M, Cronin MTD, Madden JC, Rowe PH, Johnson C, Obi A, Enoch SJ. 2007. Consensus QSAR models: do the benefits outweigh the complexity? J Chem Inf Model, 47 :1460-1468 >DOI >Link

Hewitt M, Cronin MTD, Madden JC, Rowe PH, Enoch SJ. 2007. Applying consensus models to heterogeneous datasets - Any benefit over single MLR models? DRUGS OF THE FUTURE, 32 :90-90 >Link

Hewitt M, Azam S, Enoch SJ, Madden JC, Cronin MTD. 2007. Prioritising chemicals for testing: Risk assessment based on predicted mechanism of toxic action DRUGS OF THE FUTURE, 32 :112-113 >Link

Hewitt M, Cronin MTD, Madden JC, Rowe PH, Johnson C, Obi A, Enoch SJ. 2007. Consensus QSAR models: do the benefits outweigh the complexity? J Chem Inf Model, 47 :1460-1468 >DOI >Link

Hewitt M, Cronin MTD, Madden JC, Rowe PH, Enoch SJ. 2007. Applying consensus models to heterogeneous datasets - Any benefit over single MLR models? DRUGS OF THE FUTURE, 32 :90-90 >Link

Hewitt M, Azam S, Enoch SJ, Madden JC, Cronin MTD. 2007. Prioritising chemicals for testing: Risk assessment based on predicted mechanism of toxic action DRUGS OF THE FUTURE, 32 :112-113 >Link

Hewitt M, Cronin MTD, Madden JC, Rowe PH, Johnson C, Obi A, Enoch SJ. 2007. Consensus QSAR models: do the benefits outweigh the complexity? J Chem Inf Model, 47 :1460-1468 >DOI >Link

Hewitt M, Cronin MTD, Madden JC, Rowe PH, Enoch SJ. 2007. Applying consensus models to heterogeneous datasets - Any benefit over single MLR models? DRUGS OF THE FUTURE, 32 :90-90 >Link

Hewitt M, Azam S, Enoch SJ, Madden JC, Cronin MTD. 2007. Prioritising chemicals for testing: Risk assessment based on predicted mechanism of toxic action DRUGS OF THE FUTURE, 32 :112-113 >Link

Chapters

Enoch SJ. 2010. The Use of Frontier Molecular Orbital Calculations in Predictive Toxicology Cronin M, Madden J. In Silico Toxicology Not Avail 9781849730044

Enoch SJ. 2010. The Use of Frontier Molecular Orbital Calculations in Predictive Toxicology Cronin M, Madden J. In Silico Toxicology Not Avail 9781849730044

Enoch SJ. 2010. The Use of Frontier Molecular Orbital Calculations in Predictive Toxicology Cronin M, Madden J. In Silico Toxicology Not Avail 9781849730044

Enoch SJ. 2010. The Use of Frontier Molecular Orbital Calculations in Predictive Toxicology Cronin M, Madden J. In Silico Toxicology Not Avail 9781849730044

Enoch SJ. 2009. The Use of Quantum Mechanics Derived Descriptors in Computational Toxicology Puzyn T, Leszczynski J, Cronin MTD. Recent Advances in QSAR Studies Springer Verlag 9781402097829

Enoch SJ. 2009. Chemical Category Formation and Read-Across for the Prediction of Toxicity Puzyn T, Leszczynski J, Cronin MTD. Recent Advances in QSAR Studies Springer Verlag 9781402097829

Enoch SJ. 2009. The Use of Quantum Mechanics Derived Descriptors in Computational Toxicology Puzyn T, Leszczynski J, Cronin MTD. Recent Advances in QSAR Studies Springer Verlag 9781402097829

Enoch SJ. 2009. Chemical Category Formation and Read-Across for the Prediction of Toxicity Puzyn T, Leszczynski J, Cronin MTD. Recent Advances in QSAR Studies Springer Verlag 9781402097829

Enoch SJ. 2009. The Use of Quantum Mechanics Derived Descriptors in Computational Toxicology Puzyn T, Leszczynski J, Cronin MTD. Recent Advances in QSAR Studies Springer Verlag 9781402097829

Enoch SJ. 2009. Chemical Category Formation and Read-Across for the Prediction of Toxicity Puzyn T, Leszczynski J, Cronin MTD. Recent Advances in QSAR Studies Springer Verlag 9781402097829

Enoch SJ. 2009. The Use of Quantum Mechanics Derived Descriptors in Computational Toxicology Puzyn T, Leszczynski J, Cronin MTD. Recent Advances in QSAR Studies Springer Verlag 9781402097829

Enoch SJ. 2009. Chemical Category Formation and Read-Across for the Prediction of Toxicity Puzyn T, Leszczynski J, Cronin MTD. Recent Advances in QSAR Studies Springer Verlag 9781402097829

Cronin MTD, Enoch SJ, Madden JC. 2007. Quantitative Structure-Activity Relationships for Skin Corrosivity and Sensitisation Roberts MS, Walters KA. Dermal absorption and toxicity assessment Informa HealthCare 9780849375910

Cronin MTD, Enoch SJ, Madden JC. 2007. Quantitative Structure-Activity Relationships for Skin Corrosivity and Sensitisation Roberts MS, Walters KA. Dermal absorption and toxicity assessment Informa HealthCare 9780849375910

Cronin MTD, Enoch SJ, Madden JC. 2007. Quantitative Structure-Activity Relationships for Skin Corrosivity and Sensitisation Roberts MS, Walters KA. Dermal absorption and toxicity assessment Informa HealthCare 9780849375910

Cronin MTD, Enoch SJ, Madden JC. 2007. Quantitative Structure-Activity Relationships for Skin Corrosivity and Sensitisation Roberts MS, Walters KA. Dermal absorption and toxicity assessment Informa HealthCare 9780849375910

Engagement & Impact

Award:

LUSH prize for science 2013, LUSH cosmetics

Editorial boards:

ATLA