Liverpool Skylilne

School of Biological and Environmental Sciences

Dr Rodrigo De Marco

Dr Rodrigo De Marco

Telephone: 0151 904 1893

ORCID

Biography

My research focuses on the structure, function and plasticity of behaviour, mostly in the context of neuroscience. I received a Licentiate degree and a PhD in Biology from the University of Buenos Aires. My postdoctoral work focused on cognition and neurophysiology. From 2010 until 2016, I was a Project Leader at the Max Planck Institute for Medical Research in Heidelberg. Later I was part of the University Medical Center of the Johannes Gutenberg University Mainz in Germany. I joined LJMU in February 2020.

Research
My first interests were in collective behaviour and group ergonomics. Hence my early passion for the honeybee, a pinnacle of sociability. I spent years studying Apis mellifera and discovered major trade-offs between gathering energy and information at individual and group levels. I also studied perceptual learning in mice and revealed how the interplay between visual discrimination and learning governs goal-directed choice. Additionally I conceived a behavioural assay, the L-maze, to test path integration in mice; alongside selective disruption of grid cell firing, the L-maze directly linked grid cell activity to path integration. More recently I have been studying positive development in zebrafish (Danio rerio). In doing so, I established newly developed behavioural assays, protocols for non-invasive optogenetics and high-throughput screens.

Teaching
I consider teaching essential to develop and sustain a healthy community. I encourage students to reflect on observation as a cornerstone of biology. I provide them continuously with a stimulus and let them develop their own thoughts on their own pace, and I know when to push and continue to push by demanding precise questions and answers. This helps them focus on the main points. Only then, they can ask, examine and start all over again. I like to see students being amazed when they discover a well-planned experiment proving their own hypothesis wrong. This is the point where grasping the process of science really begins. As a teacher, I focus on two concepts that matter greatly to me: maximum freedom when it comes to the decision on how to answer a question, and no freedom at all when it comes to the decision whether their answer holds true. I stimulate individual views by giving students constructive feedback and freedom to try their own approaches, and I reinforce the importance of self-consistent experiments and robust controls. All this while helping them gain confidence in their own work and ideas. As a mentor, I try my very best to extend my scientific integrity to every day teaching.

Languages

Spanish - Latin American
English
German
Italian

Degrees

University of Buenos Aires, Argentina, PhD
University of Buenos Aires, Argentina, Lic

Academic appointments

Senior Lecturer in Neuroscience, Liverpool John Moores University, 2020 - present
Project Leader, University Medical Center of the Johannes Gutenberg University Mainz, 2016 - 2019
Project Leader, Max Planck Institute for Medical Research, 2010 - 2016
Research Associate, Free University of Berlin, 2006 - 2008

Postgraduate training

Postdoctoral Fellow, Germany, Free University of Berlin, 2004 - 2006

Publications

Highlighted publications

Castillo-Ramírez L, Ryu S, De Marco RJ. 2019. Active behaviour during early development shapes glucocorticoid reactivity Scientific Reports, DOI Author Url Publisher Url Public Url

Gil M, Ancau M, Schlesiger MI, Neitz A, Allen K, De Marco RJ, Monyer H. 2017. Impaired path integration in mice with disrupted grid cell firing Nature Neuroscience, DOI Author Url Publisher Url Public Url

Ryu S, De Marco RJ. 2017. Performance on innate behaviour during early development as a function of stress level Scientific Reports, DOI Author Url Publisher Url Public Url

De Marco RJ, Thiemann T, Groneberg AH, Herget U, Ryu S. 2016. Optogenetically enhanced pituitary corticotroph cell activity post-stress onset causes rapid organizing effects on behaviour Nature Communications, DOI Author Url Publisher Url Public Url

Groneberg AH, Herget U, Ryu S, De Marco RJ. 2015. Positive taxis and sustained responsiveness to water motions in larval zebrafish Frontiers in Neural Circuits, DOI Author Url Publisher Url

De Marco RJ, Groneberg AH, Yeh C-M, Treviño M, Ryu S. 2014. The behavior of larval zebrafish reveals stressor-mediated anorexia during early vertebrate development Frontiers in Behavioral Neuroscience, DOI Author Url Publisher Url

Trevino M, Oviedo T, Jendritza P, Li S-B, Koehr G, De Marco RJ. 2013. Controlled variations in stimulus similarity during learning determine visual discrimination capacity in freely moving mice Scientific Reports, DOI Author Url Publisher Url

De Marco RJ. 2006. How bees tune their dancing according to their colony’s nectar influx: re-examining the role of the food-receivers’ ’eagerness’ Journal of Experimental Biology, DOI Author Url Publisher Url

Journal article

Castillo-Ramírez L, Ryu S, De Marco RJ. 2019. Active behaviour during early development shapes glucocorticoid reactivity Scientific Reports, DOI Author Url Publisher Url Public Url

Gil M, Ancau M, Schlesiger MI, Neitz A, Allen K, De Marco RJ, Monyer H. 2017. Impaired path integration in mice with disrupted grid cell firing Nature Neuroscience, DOI Author Url Publisher Url Public Url

Ryu S, De Marco RJ. 2017. Performance on innate behaviour during early development as a function of stress level Scientific Reports, DOI Author Url Publisher Url Public Url

De Marco RJ, Thiemann T, Groneberg AH, Herget U, Ryu S. 2016. Optogenetically enhanced pituitary corticotroph cell activity post-stress onset causes rapid organizing effects on behaviour Nature Communications, DOI Author Url Publisher Url Public Url

vom Berg-Maurer CM, Trivedi CA, Bollmann JH, De Marco RJ, Ryu S. 2016. The Severity of Acute Stress Is Represented by Increased Synchronous Activity and Recruitment of Hypothalamic CRH Neurons Journal of Neuroscience, DOI Author Url Publisher Url

Gutierrez-Triana JA, Herget U, Castillo-Ramirez LA, Lutz M, Yeh C-M, De Marco RJ, Ryu S. 2015. Manipulation of Interrenal Cell Function in Developing Zebrafish Using Genetically Targeted Ablation and an Optogenetic Tool Endocrinology, DOI Author Url Publisher Url

Groneberg AH, Herget U, Ryu S, De Marco RJ. 2015. Positive taxis and sustained responsiveness to water motions in larval zebrafish Frontiers in Neural Circuits, DOI Author Url Publisher Url

De Marco RJ, Groneberg AH, Yeh C-M, Treviño M, Ryu S. 2014. The behavior of larval zebrafish reveals stressor-mediated anorexia during early vertebrate development Frontiers in Behavioral Neuroscience, DOI Author Url Publisher Url

De Marco RJ, Groneberg AH, Yeh C-M, Castillo-Ramirez LA, Ryu S. 2013. Optogenetic elevation of endogenous glucocorticoid level in larval zebrafish Frontiers in Neural Circuits, DOI Author Url Publisher Url

Trevino M, Oviedo T, Jendritza P, Li S-B, Koehr G, De Marco RJ. 2013. Controlled variations in stimulus similarity during learning determine visual discrimination capacity in freely moving mice Scientific Reports, DOI Author Url Publisher Url

Treviño M, Aguilar-Garnica E, Jendritza P, Li S-B, Oviedo T, Köhr G, De Marco RJ. 2011. Discrimination learning with variable stimulus ’salience’ International Archives of Medicine, DOI Author Url Publisher Url

Gil M, De Marco RJ. 2010. Decoding information in the honeybee dance: revisiting the tactile hypothesis Animal Behaviour, DOI Author Url Publisher Url

Gil M, De Marco RJ. 2009. Honeybees learn the sign and magnitude of reward variations Journal of Experimental Biology, DOI Author Url Publisher Url

Gil M, Menzel R, De Marco RJ. 2009. Side-specific reward memories in honeybees Learning & Memory, DOI Author Url Publisher Url

Núñez JA, De Marco RJ. 2009. Functional Fractals in Biology Biological Theory, DOI Publisher Url

Seefeldt S, De Marco RJ. 2008. The response of the honeybee dance to uncertain rewards Journal of Experimental Biology, DOI Author Url Publisher Url

Gil M, Menzel R, De Marco RJ. 2008. Does an Insect’s Unconditioned Response to Sucrose Reveal Expectations of Reward? PLoS ONE, DOI Author Url Publisher Url

De Marco RJ, Gurevitz JM, Menzel R. 2008. Variability in the encoding of spatial information by dancing bees Journal of Experimental Biology, DOI Author Url Publisher Url

Gil M, De Marco RJ, Menzel R. 2007. Learning reward expectations in honeybees Learning & Memory, DOI Author Url Publisher Url

Núñez JA, De Marco RJ. 2007. Technology and the Foundations of Biology Biological Theory, DOI Publisher Url

Menzel R, De Marco RJ, Greggers U. 2006. Spatial memory, navigation and dance behaviour in Apis mellifera Journal of Comparative Physiology A, DOI Author Url Publisher Url

De Marco RJ. 2006. How bees tune their dancing according to their colony’s nectar influx: re-examining the role of the food-receivers’ ’eagerness’ Journal of Experimental Biology, DOI Author Url Publisher Url

Gil M, De Marco RJ. 2005. Apis mellifera bees acquire long-term olfactory memories within the colony Biology Letters, DOI Author Url Publisher Url

De Marco RJ, Menzel R. 2005. Encoding spatial information in the waggle dance Journal of Experimental Biology, DOI Author Url Publisher Url

De Marco RJ, Gil M, Farina WM. 2005. Does an increase in reward affect the precision of the encoding of directional information in the honeybee waggle dance? Journal of Comparative Physiology A, DOI Author Url Publisher Url

Gil M, De Marco RJ. 2005. Olfactory learning by means of trophallaxis in Apis mellifera Journal of Experimental Biology, DOI Author Url Publisher Url

De Marco RJ, Farina WM. 2003. Trophallaxis in forager honeybees (Apis mellifera): resource uncertainty enhances begging contacts? Journal of Comparative Physiology A, DOI Author Url Publisher Url

De Marco RJ, Farina WM. 2001. Changes in food source profitability affect the trophallactic and dance behavior of forager honeybees ( Apis mellifera L.) Behavioral Ecology and Sociobiology, DOI Author Url Publisher Url

De Marco RJ, Gürtler RE, Salomón OD, Chuit R. 1999. Small-Scale Field Trial of a Sensing Device for Detecting Peridomestic Populations ofTriatoma infestans(Hemiptera: Reduviidae) in Northwestern Argentina Journal of Medical Entomology, DOI Author Url Publisher Url

Book

Ryu S, De Marco RJ. Optogenetic Interpellation of Behavior Employing Unrestrained Zebrafish Larvae 9781493974153 DOI Publisher Url

De Marco RJ, Menzel R. Learning and Memory in Communication and Navigation in Insects 9780123705099 DOI Publisher Url