Liverpool Skylilne

Sport and Exercise Sciences

Prof Jatin Burniston

Prof Jatin Burniston

Telephone: 0151 904 6265

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ORCID
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Biography

My research interests centre on the use of proteomics to study muscle adaptation in the context of exercise training and the health benefits of exercise against non-communicable diseases and ageing. I established the first proteomics facility with a specific focus on exercise physiology and we published the first work reporting proteomic analysis of the responses of muscle to exercise training.

I strive to continue pioneering the field of exercise proteomics, and I consider myself a champion of the application of non-targeted '-omic' research in exercise physiology.

I serve on the Editorial Board of the American Physiological Society (APS) journal, Physiological Genomics, and I am a Fellow of the European College of Sports Sciences (ECSS) and a member of the ECSS Scientific Committee.

I lead the MSc Exercise Physiology programme at LJMU and I deliver the “Molecular Exercise Physiology" module, which includes practical training in wet laboratory techniques including proteomics. I contributed to the indicative text in this area, entitled "Molecular Exercise Physiology: An Introduction" and I regularly deliver invited presentations at national and international conferences.

Degrees

2003, Liverpool John Moores University, United Kingdom, PhD
2000, University of Portsmouth, United Kingdom, BSc (Hons)

Academic appointments

Professor of Proteomics, Liverpool John Moores University, 2015 - present
Reader in Molecular Physiology, Research Institute for Sport & Exercise Sciences, Liverpool John Moores University, 2010 - 2015
Honorary Fellow, School of Clinical Sciences, University of Liverpool, 2010 - present

Publications

Highlighted publications

Burniston JG. 2009. Adaptation of the rat cardiac proteome in response to intensity-controlled endurance exercise. Proteomics, 9 :106-115 >DOI >Link

Holloway KV, O'Gorman M, Woods P, Morton JP, Evans L, Cable NT, Goldspink DF, Burniston JG. 2009. Proteomic investigation of changes in human vastus lateralis muscle in response to interval-exercise training. Proteomics, 9 :5155-5174 >DOI >Link

Burniston JG. 2009. Adaptation of the rat cardiac proteome in response to intensity-controlled endurance exercise. Proteomics, 9 :106-115 >DOI >Link

Holloway KV, O'Gorman M, Woods P, Morton JP, Evans L, Cable NT, Goldspink DF, Burniston JG. 2009. Proteomic investigation of changes in human vastus lateralis muscle in response to interval-exercise training. Proteomics, 9 :5155-5174 >DOI >Link

Burniston JG. 2009. Adaptation of the rat cardiac proteome in response to intensity-controlled endurance exercise. Proteomics, 9 :106-115 >DOI >Link

Holloway KV, O'Gorman M, Woods P, Morton JP, Evans L, Cable NT, Goldspink DF, Burniston JG. 2009. Proteomic investigation of changes in human vastus lateralis muscle in response to interval-exercise training. Proteomics, 9 :5155-5174 >DOI >Link

Burniston JG. 2008. Changes in the rat skeletal muscle proteome induced by moderate-intensity endurance exercise. Biochim Biophys Acta, 1784 :1077-1086 >DOI >Link

Burniston JG. 2008. Changes in the rat skeletal muscle proteome induced by moderate-intensity endurance exercise. Biochim Biophys Acta, 1784 :1077-1086 >DOI >Link

Burniston JG. 2008. Changes in the rat skeletal muscle proteome induced by moderate-intensity endurance exercise. Biochim Biophys Acta, 1784 :1077-1086 >DOI >Link

Journal article

Burniston JG, Connolly JB. 2010. Characterisation of isoform-specific tryptic peptides of rat cardiac myosin heavy chains using automated liquid chromatography-matrix assisted laser desorption ionisation (LC-MALDI) mass spectrometry. Int J Cardiol, 140 :363-366 >DOI >Link

Watt KI, Judson R, Medlow P, Reid K, Kurth TB, Burniston JG, Ratkevicius A, De Bari C, Wackerhage H. 2010. Yap is a novel regulator of C2C12 myogenesis. Biochem Biophys Res Commun, 393 :619-624 >DOI >Link

Burniston JG, Connolly JB. 2010. Characterisation of isoform-specific tryptic peptides of rat cardiac myosin heavy chains using automated liquid chromatography-matrix assisted laser desorption ionisation (LC-MALDI) mass spectrometry. Int J Cardiol, 140 :363-366 >DOI >Link

Watt KI, Judson R, Medlow P, Reid K, Kurth TB, Burniston JG, Ratkevicius A, De Bari C, Wackerhage H. 2010. Yap is a novel regulator of C2C12 myogenesis. Biochem Biophys Res Commun, 393 :619-624 >DOI >Link

Burniston JG, Connolly JB. 2010. Characterisation of isoform-specific tryptic peptides of rat cardiac myosin heavy chains using automated liquid chromatography-matrix assisted laser desorption ionisation (LC-MALDI) mass spectrometry. Int J Cardiol, 140 :363-366 >DOI >Link

Watt KI, Judson R, Medlow P, Reid K, Kurth TB, Burniston JG, Ratkevicius A, De Bari C, Wackerhage H. 2010. Yap is a novel regulator of C2C12 myogenesis. Biochem Biophys Res Commun, 393 :619-624 >DOI >Link

Burniston JG. 2009. Adaptation of the rat cardiac proteome in response to intensity-controlled endurance exercise. Proteomics, 9 :106-115 >DOI >Link

Holloway KV, O'Gorman M, Woods P, Morton JP, Evans L, Cable NT, Goldspink DF, Burniston JG. 2009. Proteomic investigation of changes in human vastus lateralis muscle in response to interval-exercise training. Proteomics, 9 :5155-5174 >DOI >Link

Morton JP, Holloway K, Woods P, Cable NT, Burniston J, Evans L, Kayani AC, McArdle A. 2009. Exercise training-induced gender-specific heat shock protein adaptations in human skeletal muscle. Muscle Nerve, 39 :230-233 >DOI >Link

Burniston JG. 2009. Adaptation of the rat cardiac proteome in response to intensity-controlled endurance exercise. Proteomics, 9 :106-115 >DOI >Link

Holloway KV, O'Gorman M, Woods P, Morton JP, Evans L, Cable NT, Goldspink DF, Burniston JG. 2009. Proteomic investigation of changes in human vastus lateralis muscle in response to interval-exercise training. Proteomics, 9 :5155-5174 >DOI >Link

Morton JP, Holloway K, Woods P, Cable NT, Burniston J, Evans L, Kayani AC, McArdle A. 2009. Exercise training-induced gender-specific heat shock protein adaptations in human skeletal muscle. Muscle Nerve, 39 :230-233 >DOI >Link

Burniston JG. 2009. Adaptation of the rat cardiac proteome in response to intensity-controlled endurance exercise. Proteomics, 9 :106-115 >DOI >Link

Holloway KV, O'Gorman M, Woods P, Morton JP, Evans L, Cable NT, Goldspink DF, Burniston JG. 2009. Proteomic investigation of changes in human vastus lateralis muscle in response to interval-exercise training. Proteomics, 9 :5155-5174 >DOI >Link

Morton JP, Holloway K, Woods P, Cable NT, Burniston J, Evans L, Kayani AC, McArdle A. 2009. Exercise training-induced gender-specific heat shock protein adaptations in human skeletal muscle. Muscle Nerve, 39 :230-233 >DOI >Link

Burniston JG. 2008. Changes in the rat skeletal muscle proteome induced by moderate-intensity endurance exercise. Biochim Biophys Acta, 1784 :1077-1086 >DOI >Link

Burniston JG. 2008. Changes in the rat skeletal muscle proteome induced by moderate-intensity endurance exercise. Biochim Biophys Acta, 1784 :1077-1086 >DOI >Link

Burniston JG. 2008. Changes in the rat skeletal muscle proteome induced by moderate-intensity endurance exercise. Biochim Biophys Acta, 1784 :1077-1086 >DOI >Link

Burniston JG, McLean L, Beynon RJ, Goldspink DF. 2007. Anabolic effects of a non-myotoxic dose of the beta2-adrenergic receptor agonist clenbuterol on rat plantaris muscle. Muscle Nerve, 35 :217-223 >DOI >Link

Burniston JG. 2007. Left ventricular assist devices and drug therapy in heart failure. N Engl J Med, 356 :870 >Link

Burniston JG, McLean L, Beynon RJ, Goldspink DF. 2007. Anabolic effects of a non-myotoxic dose of the beta2-adrenergic receptor agonist clenbuterol on rat plantaris muscle. Muscle Nerve, 35 :217-223 >DOI >Link

Burniston JG. 2007. Left ventricular assist devices and drug therapy in heart failure. N Engl J Med, 356 :870 >Link

Burniston JG, McLean L, Beynon RJ, Goldspink DF. 2007. Anabolic effects of a non-myotoxic dose of the beta2-adrenergic receptor agonist clenbuterol on rat plantaris muscle. Muscle Nerve, 35 :217-223 >DOI >Link

Burniston JG. 2007. Left ventricular assist devices and drug therapy in heart failure. N Engl J Med, 356 :870 >Link

Burniston JG, Clark WA, Tan L-B, Goldspink DF. 2006. Dose-dependent separation of the hypertrophic and myotoxic effects of the beta(2)-adrenergic receptor agonist clenbuterol in rat striated muscles. Muscle Nerve, 33 :655-663 >DOI >Link

Burniston JG, Tan L-B, Goldspink DF. 2006. Relative myotoxic and haemodynamic effects of the beta-agonists fenoterol and clenbuterol measured in conscious unrestrained rats. Exp Physiol, 91 :1041-1049 >DOI >Link

Connolly JB, Burniston JG. 2006. LC-MALDI investigation of membrane-enriched protein fraction of rat heart muscle MOLECULAR & CELLULAR PROTEOMICS, 5 :S12-S12 >Link

Burniston JG, Clark WA, Tan L-B, Goldspink DF. 2006. Dose-dependent separation of the hypertrophic and myotoxic effects of the beta(2)-adrenergic receptor agonist clenbuterol in rat striated muscles. Muscle Nerve, 33 :655-663 >DOI >Link

Burniston JG, Tan L-B, Goldspink DF. 2006. Relative myotoxic and haemodynamic effects of the beta-agonists fenoterol and clenbuterol measured in conscious unrestrained rats. Exp Physiol, 91 :1041-1049 >DOI >Link

Connolly JB, Burniston JG. 2006. LC-MALDI investigation of membrane-enriched protein fraction of rat heart muscle MOLECULAR & CELLULAR PROTEOMICS, 5 :S12-S12 >Link

Burniston JG, Clark WA, Tan L-B, Goldspink DF. 2006. Dose-dependent separation of the hypertrophic and myotoxic effects of the beta(2)-adrenergic receptor agonist clenbuterol in rat striated muscles. Muscle Nerve, 33 :655-663 >DOI >Link

Burniston JG, Tan L-B, Goldspink DF. 2006. Relative myotoxic and haemodynamic effects of the beta-agonists fenoterol and clenbuterol measured in conscious unrestrained rats. Exp Physiol, 91 :1041-1049 >DOI >Link

Connolly JB, Burniston JG. 2006. LC-MALDI investigation of membrane-enriched protein fraction of rat heart muscle MOLECULAR & CELLULAR PROTEOMICS, 5 :S12-S12 >Link

Burniston JG, Tan L-B, Goldspink DF. 2005. beta2-Adrenergic receptor stimulation in vivo induces apoptosis in the rat heart and soleus muscle. J Appl Physiol (1985), 98 :1379-1386 >DOI >Link

Burniston JG, Saini A, Tan L-B, Goldspink DF. 2005. Aldosterone induces myocyte apoptosis in the heart and skeletal muscles of rats in vivo. J Mol Cell Cardiol, 39 :395-399 >DOI >Link

Burniston JG, Saini A, Tan L-B, Goldspink DF. 2005. Angiotensin II induces apoptosis in vivo in skeletal, as well as cardiac, muscle of the rat. Exp Physiol, 90 :755-761 >DOI >Link

Burniston JG, Chester N, Clark WA, Tan L-B, Goldspink DF. 2005. Dose-dependent apoptotic and necrotic myocyte death induced by the beta2-adrenergic receptor agonist, clenbuterol. Muscle Nerve, 32 :767-774 >DOI >Link

Burniston JG, Ellison GM, Clark WA, Goldspink DF, Tan L-B. 2005. Relative toxicity of cardiotonic agents: some induce more cardiac and skeletal myocyte apoptosis and necrosis in vivo than others. Cardiovasc Toxicol, 5 :355-364 >Link

Burniston JG, Tan L-B, Goldspink DF. 2005. beta2-Adrenergic receptor stimulation in vivo induces apoptosis in the rat heart and soleus muscle. J Appl Physiol (1985), 98 :1379-1386 >DOI >Link

Burniston JG, Saini A, Tan L-B, Goldspink DF. 2005. Aldosterone induces myocyte apoptosis in the heart and skeletal muscles of rats in vivo. J Mol Cell Cardiol, 39 :395-399 >DOI >Link

Burniston JG, Saini A, Tan L-B, Goldspink DF. 2005. Angiotensin II induces apoptosis in vivo in skeletal, as well as cardiac, muscle of the rat. Exp Physiol, 90 :755-761 >DOI >Link

Burniston JG, Chester N, Clark WA, Tan L-B, Goldspink DF. 2005. Dose-dependent apoptotic and necrotic myocyte death induced by the beta2-adrenergic receptor agonist, clenbuterol. Muscle Nerve, 32 :767-774 >DOI >Link

Burniston JG, Ellison GM, Clark WA, Goldspink DF, Tan L-B. 2005. Relative toxicity of cardiotonic agents: some induce more cardiac and skeletal myocyte apoptosis and necrosis in vivo than others. Cardiovasc Toxicol, 5 :355-364 >Link

Burniston JG, Tan L-B, Goldspink DF. 2005. beta2-Adrenergic receptor stimulation in vivo induces apoptosis in the rat heart and soleus muscle. J Appl Physiol (1985), 98 :1379-1386 >DOI >Link

Burniston JG, Saini A, Tan L-B, Goldspink DF. 2005. Aldosterone induces myocyte apoptosis in the heart and skeletal muscles of rats in vivo. J Mol Cell Cardiol, 39 :395-399 >DOI >Link

Burniston JG, Saini A, Tan L-B, Goldspink DF. 2005. Angiotensin II induces apoptosis in vivo in skeletal, as well as cardiac, muscle of the rat. Exp Physiol, 90 :755-761 >DOI >Link

Burniston JG, Chester N, Clark WA, Tan L-B, Goldspink DF. 2005. Dose-dependent apoptotic and necrotic myocyte death induced by the beta2-adrenergic receptor agonist, clenbuterol. Muscle Nerve, 32 :767-774 >DOI >Link

Burniston JG, Ellison GM, Clark WA, Goldspink DF, Tan L-B. 2005. Relative toxicity of cardiotonic agents: some induce more cardiac and skeletal myocyte apoptosis and necrosis in vivo than others. Cardiovasc Toxicol, 5 :355-364 >Link

Goldspink DF, Burniston JG, Ellison GM, Clark WA, Tan L-B. 2004. Catecholamine-induced apoptosis and necrosis in cardiac and skeletal myocytes of the rat in vivo: the same or separate death pathways? Exp Physiol, 89 :407-416 >DOI >Link

Goldspink DF, Burniston JG, Ellison GM, Clark WA, Tan L-B. 2004. Catecholamine-induced apoptosis and necrosis in cardiac and skeletal myocytes of the rat in vivo: the same or separate death pathways? Exp Physiol, 89 :407-416 >DOI >Link

Goldspink DF, Burniston JG, Ellison GM, Clark WA, Tan L-B. 2004. Catecholamine-induced apoptosis and necrosis in cardiac and skeletal myocytes of the rat in vivo: the same or separate death pathways? Exp Physiol, 89 :407-416 >DOI >Link

Tan L-B, Burniston JG, Clark WA, Ng Y, Goldspink DF. 2003. Characterization of adrenoceptor involvement in skeletal and cardiac myotoxicity Induced by sympathomimetic agents: toward a new bioassay for beta-blockers. J Cardiovasc Pharmacol, 41 :518-525 >DOI >Link

Goldspink DF, Burniston JG, Tan L-B. 2003. Cardiomyocyte death and the ageing and failing heart. Exp Physiol, 88 :447-458 >Link

Tan L-B, Burniston JG, Clark WA, Ng Y, Goldspink DF. 2003. Characterization of adrenoceptor involvement in skeletal and cardiac myotoxicity Induced by sympathomimetic agents: toward a new bioassay for beta-blockers. J Cardiovasc Pharmacol, 41 :518-525 >DOI >Link

Goldspink DF, Burniston JG, Tan L-B. 2003. Cardiomyocyte death and the ageing and failing heart. Exp Physiol, 88 :447-458 >Link

Tan L-B, Burniston JG, Clark WA, Ng Y, Goldspink DF. 2003. Characterization of adrenoceptor involvement in skeletal and cardiac myotoxicity Induced by sympathomimetic agents: toward a new bioassay for beta-blockers. J Cardiovasc Pharmacol, 41 :518-525 >DOI >Link

Goldspink DF, Burniston JG, Tan L-B. 2003. Cardiomyocyte death and the ageing and failing heart. Exp Physiol, 88 :447-458 >Link

Burniston JG, Ng Y, Clark WA, Colyer J, Tan L-B, Goldspink DF. 2002. Myotoxic effects of clenbuterol in the rat heart and soleus muscle. J Appl Physiol (1985), 93 :1824-1832 >DOI >Link

Ng Y, Goldspink DF, Burniston JG, Clark WA, Colyer J, Tan LB. 2002. Characterisation of isoprenaline myotoxicity on slow-twitch skeletal versus cardiac muscle. Int J Cardiol, 86 :299-309 >DOI >Link

Burniston JG, Ng Y, Clark WA, Colyer J, Tan L-B, Goldspink DF. 2002. Myotoxic effects of clenbuterol in the rat heart and soleus muscle. J Appl Physiol (1985), 93 :1824-1832 >DOI >Link

Ng Y, Goldspink DF, Burniston JG, Clark WA, Colyer J, Tan LB. 2002. Characterisation of isoprenaline myotoxicity on slow-twitch skeletal versus cardiac muscle. Int J Cardiol, 86 :299-309 >DOI >Link

Burniston JG, Ng Y, Clark WA, Colyer J, Tan L-B, Goldspink DF. 2002. Myotoxic effects of clenbuterol in the rat heart and soleus muscle. J Appl Physiol (1985), 93 :1824-1832 >DOI >Link

Ng Y, Goldspink DF, Burniston JG, Clark WA, Colyer J, Tan LB. 2002. Characterisation of isoprenaline myotoxicity on slow-twitch skeletal versus cardiac muscle. Int J Cardiol, 86 :299-309 >DOI >Link

Conference publication

Burniston JG, McLean L, Beynon R, Goldspink D. 2006. Functional, cellular and molecular changes induced in the rat plantaris muscle by a low, non-myotoxic dose of the beta(2)-agonist clenbuterol FASEB JOURNAL, Experimental Biology 2006 Meeting 20 :A808-A808 >Link

Burniston JG, Tan L-B, Goldspink DF. 2006. Relative cardiotoxic and haemodynamic effects of the beta-agonists fenoterol and clenbuterol measured in conscious unrestrained rats JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 28th Annual International-Society-for-Heart-Research North American Section Meeting 40 :1010-1011 >DOI >Link

Burniston JG, McLean L, Beynon R, Goldspink D. 2006. Functional, cellular and molecular changes induced in the rat plantaris muscle by a low, non-myotoxic dose of the beta(2)-agonist clenbuterol FASEB JOURNAL, Experimental Biology 2006 Meeting 20 :A808-A808 >Link

Burniston JG, Tan L-B, Goldspink DF. 2006. Relative cardiotoxic and haemodynamic effects of the beta-agonists fenoterol and clenbuterol measured in conscious unrestrained rats JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 28th Annual International-Society-for-Heart-Research North American Section Meeting 40 :1010-1011 >DOI >Link

Burniston JG, McLean L, Beynon R, Goldspink D. 2006. Functional, cellular and molecular changes induced in the rat plantaris muscle by a low, non-myotoxic dose of the beta(2)-agonist clenbuterol FASEB JOURNAL, Experimental Biology 2006 Meeting 20 :A808-A808 >Link

Burniston JG, Tan L-B, Goldspink DF. 2006. Relative cardiotoxic and haemodynamic effects of the beta-agonists fenoterol and clenbuterol measured in conscious unrestrained rats JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 28th Annual International-Society-for-Heart-Research North American Section Meeting 40 :1010-1011 >DOI >Link

Burniston J, Tan LB, Goldspink D. 2003. Is the anabolic adrenergic agonist clenbuterol safe? JOURNAL OF SPORTS SCIENCES, 12th Commonwealth International Sport Conference 21 :312-313 >Link

Burniston J, Tan LB, Goldspink D. 2003. Is the anabolic adrenergic agonist clenbuterol safe? JOURNAL OF SPORTS SCIENCES, 12th Commonwealth International Sport Conference 21 :312-313 >Link

Burniston J, Tan LB, Goldspink D. 2003. Is the anabolic adrenergic agonist clenbuterol safe? JOURNAL OF SPORTS SCIENCES, 12th Commonwealth International Sport Conference 21 :312-313 >Link

Burniston JG, Tan LB, Goldspink DF. 2002. beta(2)-adrenergic receptor stimulation by clenbuterol in vivo induces apoptosis in the rat heart JOURNAL OF PHYSIOLOGY-LONDON, Conference of the Physiological-Society 543 :38P-39P >Link

Burniston JG, Tan LB, Goldspink DF. 2002. beta(2)-adrenergic receptor stimulation by clenbuterol in vivo induces apoptosis in the rat heart JOURNAL OF PHYSIOLOGY-LONDON, Conference of the Physiological-Society 543 :38P-39P >Link

Burniston JG, Tan LB, Goldspink DF. 2002. beta(2)-adrenergic receptor stimulation by clenbuterol in vivo induces apoptosis in the rat heart JOURNAL OF PHYSIOLOGY-LONDON, Conference of the Physiological-Society 543 :38P-39P >Link

Engagement & Impact

Conference organisation:

16th Congress of the European College of Sport Sciences, Member of local organising committee and Scientific committee, Invited symposium speaker, http://www.ecss-congress.eu/2011/

Editorial boards:

Journal of Integrated OMICS, Associate Editor, http://www.jiomics.com/index.php/jio

Organelles Proteomics, Editorial Advisory Board, http://www.degruyter.com/view/j/orpr

BioMed Research International, Invited lead guest editor for a special issue in cardiac proteomics, http://www.hindawi.com/journals/bmri/si/846423/cfp/

Proteomes, Associate Editor, http://www.mdpi.com/journal/proteomes

Physiological Genomics, Member of the Editorial Board, http://physiolgenomics.physiology.org/

External collaboration:

https://www.physiology.med.umich.edu/research/profiles/sbritton.htm, University of Michigan, Prof. Steve Briton Prof. Lauren Koch

http://207.96.13.115/research/faculty/bios/cgmr/Hoffman_E.aspx, Children's National Medical Center, Prof Eric Hoffman Dr Yi-Wen Chen Dr Yetrib Hathout

University of Jyvaskyla, Prof. Heikki Kainulainen

http://www.liv.ac.uk/ageing-and-chronic-disease/staff/john-wilding/, University of Liverpool, Prof. John Wilding

http://www.sthk.nhs.uk/pages/Departments.aspx?iPageId=7964, St Helens and Knowsley NHS Trust, Prof. Kevin Hardy

http://www.biology.ucr.edu/people/faculty/Garland.html, University of California-Riverside, Prof. Ted Garland

http://www.liv.ac.uk/infection-and-global-health/staff/jonathan-wastling/, University of Liverpool, Prof. Jonathan Wastling

University of Florida, Scott Powers

External PGR examinations performed:

Manchester Metropolitan University, PhD, Structure-Function Relationship and Plasticity in Old Mouse Muscle

External PGR Supervision - completed students:

Liverpool John Moores University, PhD

Fellowships:

Honorary Fellow, School of Clinical Sciences, University of Liverpool

Membership of professional bodies:

Full Member, Physiological Society, http://www.physoc.org/

Full member, Biochemical Society, http://www.biochemistry.org/

Full member, American Physiological Society, http://www.the-aps.org/

Research Grants Awarded:

Sub-contract on National Institutes of Health R01 AR064189, Mechanisms of exercise protection against ventilator-induced diaphragm dysfunction, Scott K Powers, Grant value (£): 20,000, Duration of research project: 0/6

Teaching qualification:

Fellow of the Higher Education Authority (FHEA)