PhD title: Inhibition of adipose tissue lipolysis during exercise to enhance the effectiveness of a walking programme to improve insulin sensitivity in people with pre-diabetes.
PhD start date: 14th November 2018
Project description: For my first project I will investigate GLUT4 translocation during a hyperinsulinemic-euglycemic clamp (HEC) to show that with high free fatty acid availability, GLUT4 translocation in skeletal muscle is impaired. My second study and third study will investigate whether a novel combined exercise and pharmacological intervention can improve insulin sensitivity and glycemic control in people with pre-diabetes.
Biography: I have been at LJMU for the past 7 years in the Sport and Exercise department, completing both my undergraduate degree followed by my MSc in Exercise Physiology. I am now in the final year of my PhD. Outside of academia, I enjoy running, and really good coffee.
2021, Liverpool John Moores University, United Kingdom, PhD - Exercise Metabolism
2018, Liverpool John Moores University, United Kingdom, Master of Science in Exercise Physiology - Distinction
2017, Liverpool John Moores University, United Kingdom, Bachelor of Science in Sport and Exercise Science - 2:1
Barrett J. 2023. The Importance of Intramuscular Triglyceride Turnover on Skeletal Muscle Insulin Sensitvity Shepherd S, Strauss J, Wagenmakers A, Cuthbertson D. Public Url
Malik Z, Bowden Davies K, Hall E, Barrett J, Pullinger S, Erskine RM, Shepherd SO, Iqbal Z, Edwards BJ, Burniston JG. 2020. Diurnal differences in human muscle isometric force and rate of force development in vivo are associated with differential phosphorylation of sarcomeric M-band proteins. Proteomes, 8 DOI Author Url Publisher Url Public Url
Burniston J, Barrett J, Bennett S, Stead C, Louis J, Close G, Lisboa P. 2020. Dynamic Proteome Profiling of Protein Fractional and Molar Synthesis Rates in Human Muscle
The effects of chronic low frequency stimulation on the synthesis and degradation of Creatine Kinase in rat tibialis anterior., BASES Student Conference 2017, Plymouth, Oral presentation. 2017