Liverpool Skylilne

Sport and Exercise Sciences

Dr Thomas O'Brien

Dr Thomas O'Brien

Publications

Highlighted publications

Kalkman BM, Bar-On L, Cenni F, Maganaris CN, Bass A, Holmes G, Desloovere K, Barton GJ, O'Brien TD. 2018. Medial gastrocnemius muscle stiffness cannot explain the increased ankle joint range of motion following passive stretching in children with cerebral palsy EXPERIMENTAL PHYSIOLOGY, 103 :350-357 >DOI >Link

Noyes J, Spencer LH, Bray N, Kubis H-P, Hastings RP, Jackson M, O'Brien TD. 2017. Conceptualization of physical exercise and keeping fit by child wheelchair users and their parents. Journal of Advanced Nursing, :1111-1123 >DOI >Link

Apps C, Sterzing T, O'Brien T, Lake M. 2016. Lower limb joint stiffness and muscle co-contraction adaptations to instability footwear during locomotion Journal of Electromyography and Kinesiology, 31 :55-62 >DOI

Wilkinson TJ, Lemmey AB, Jones JG, Sheikh F, Ahmad YA, Chitale S, Maddison PJ, O'Brien TD. 2016. Can Creatine Supplementation Improve Body Composition and Objective Physical Function in Rheumatoid Arthritis Patients? A Randomized Controlled Trial Arthritis Care and Research, 68 :729-737 >DOI

King SL, Vanicek N, O'Brien TD. 2015. Gastrocnemius muscle architecture and Achilles tendon properties influence walking distance in claudicants with peripheral arterial disease. Muscle & nerve, >DOI

King SL, Vanicek N, O'Brien TD. 2015. Dynamic muscle quality of the plantarflexors is impaired in claudicants with peripheral arterial disease and associated with poorer walking endurance Journal of Vascular Surgery,

Kalkman B, Bar-On L, Cenni F, Maganaris C, Bass A, Holmes G, Deslovere K, Barton GJ, O'Brien T. Achilles tendon moment arm length is smaller in children with cerebral palsy than in typically developing children Journal of Biomechanics,

Lemmey AB, Wilkinson T, Clayton B, Sheikh F, Whale J, Jones H, Ahmed Y, Chitale S, Jones J, Maddison PJ, O'Brien TD. Tight control of disease activity fails to improve body composition or physical function in rheumatoid arthritis patients Rheumatology,

Journal article

King SL, Vanicek N, O'Brien TD. 2018. Joint moment strategies during stair descent in patients with peripheral arterial disease and intermittent claudication GAIT & POSTURE, 62 :359-365 >DOI >Link

Seaborne RA, Strauss J, Cocks M, Shepherd S, O'Brien TD, van Someren KA, Bell PG, Murgatroyd C, Morton JP, Stewart CE, Sharples AP. 2018. Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy Scientific Reports, 8 >DOI

Kalkman BM, Bar-On L, Cenni F, Maganaris CN, Bass A, Holmes G, Desloovere K, Barton GJ, O'Brien TD. 2018. Medial gastrocnemius muscle stiffness cannot explain the increased ankle joint range of motion following passive stretching in children with cerebral palsy EXPERIMENTAL PHYSIOLOGY, 103 :350-357 >DOI >Link

Apps C, Sterzing T, O'Brien T, Ding R, Lake M. 2017. Biomechanical locomotion adaptations on uneven surfaces can be simulated with a randomly deforming shoe midsole Footwear Science, 9 :65-77 >DOI

King SL, Vanicek N, O'Brien TD. 2017. Sagittal plane joint kinetics during stair ascent in patients with peripheral arterial disease and intermittent claudication GAIT & POSTURE, 55 :81-86 >DOI >Link

Noyes J, Spencer LH, Bray N, Kubis H-P, Hastings RP, Jackson M, O'Brien TD. 2017. Conceptualization of physical exercise and keeping fit by child wheelchair users and their parents. Journal of Advanced Nursing, :1111-1123 >DOI >Link

Long D, Dotan R, Pitt B, McKinlay B, O'Brien TD, Tokuno C, Falk B. 2017. The Electromyographic Threshold in Girls and Women. Pediatric Exercise Science, 29 :84-93 >DOI

Apps C, Sterzing T, O'Brien T, Lake M. 2016. Lower limb joint stiffness and muscle co-contraction adaptations to instability footwear during locomotion Journal of Electromyography and Kinesiology, 31 :55-62 >DOI

O'Brien TD, Noyes J, Spencer LH, Kubis H-P, Hastings RP, Whitaker R. 2016. Systematic review of physical activity and exercise interventions to improve health, fitness and well-being of children and young people who use wheelchairs. BMJ Open Sport Exerc Med, 2 :e000109-e000109 >DOI >Link

Wilkinson T, Lemmey A, Sheikh F, Ahmad Y, Chitale S, Jones J, Maddison P, O'Brien TD. 2016. Effects of oral creatine supplementation on body composition and objective physical function in rheumatoid arthritis patients. A randomised controlled trial World Biomedical Frontiers,

Dotan R, Jenkins G, O'Brien TD, Hansen S, Falk B. 2016. Torque-onset determination: Unintended consequences of the threshold method. Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology, 31 :7-13

Wilkinson TJ, Lemmey AB, Jones JG, Sheikh F, Ahmad YA, Chitale S, Maddison PJ, O'Brien TD. 2016. Can Creatine Supplementation Improve Body Composition and Objective Physical Function in Rheumatoid Arthritis Patients? A Randomized Controlled Trial Arthritis Care and Research, 68 :729-737 >DOI

Wilkinson TJ, Lemmey AB, O'Brien TD, Jones JG. 2015. Significant muscle loss following intramuscular corticosteroid injection used to treat active rheumatoid arthritis: a case report Journal of Rheumatology and Orthopedics, 2 :2-2 >DOI

Pitt B, Dotan R, Millar J, Long D, Tokuno C, O’Brien T, Falk B. 2015. The electromyographic threshold in boys and men European Journal of Applied Physiology, 115 :1273-1281 >DOI

Alcock L, O'Brien TD, Vanicek N. 2015. Biomechanical demands of the 2-step transitional gait cycles linking level gait and stair descent gait in older women JOURNAL OF BIOMECHANICS, 48 :4191-4197 >DOI >Link

King SL, Vanicek N, O'Brien TD. 2015. Gastrocnemius muscle architecture and Achilles tendon properties influence walking distance in claudicants with peripheral arterial disease. Muscle & nerve, >DOI

King SL, Vanicek N, O'Brien TD. 2015. Dynamic muscle quality of the plantarflexors is impaired in claudicants with peripheral arterial disease and associated with poorer walking endurance Journal of Vascular Surgery,

O'Brien TD, Noyes J, Spencer LH, Kubis H-P, Edwards RT, Bray N, Whitaker R. 2015. Well-being, health and fitness of children who use wheelchairs: Feasibility study protocol to develop child-centred 'keep-fit' exercise interventions JOURNAL OF ADVANCED NURSING, 71 :430-440 >DOI >Link

Alcock L, O'Brien TD, Vanicek N. 2015. Age-related changes in physical functioning: correlates between objective and self-reported outcomes PHYSIOTHERAPY, 101 :204-213 >DOI >Link

Wilkinson TJ. 2014. Oral creatine supplementation: A potential adjunct therapy for rheumatoid arthritis patients World Journal of Rheumatology, 4 :22-22 >DOI

O'Brien TD, Noyes J, Spencer LH, Kubis HP, Hastings RP, Edwards RT, Bray N, Whitaker R. 2014. 'Keep fit' exercise interventions to improve health, fitness and well-being of children and young people who use wheelchairs: Mixed-method systematic review protocol Journal of Advanced Nursing, 70 :2942-2951 >DOI

O'Brien TD, Noyes J, Spencer LH, KUBIS HP, HASTINGS RP, EDWARDS RT, BRAY N, WHITAKER R. 2014. ‘Keep fit’ exercise interventions to improve health, fitness and wellbeing of children and young people who use wheelchairs: Mixed- method systematic review protocol Journal of Advanced Nursing,

Alcock L, Vanicek N, O'Brien TD. 2013. Biomechanical demands differentiate transitioning vs. continuous stair ascent gait in older women Clinical Biomechanics, >DOI

Alcock L, Vanicek N, O'Brien TD. 2013. Alterations in gait speed and age do not fully explain the changes in gait mechanics associated with healthy older women. Gait Posture, 37 :586-592 >DOI >Link

Herzog W, Sartorio A, Lafortuna CL, Kanehisa H, Fukunaga T, Dotan R, Falk B, Wood LE, Tonson A, Le Fur Y, Cozzone PJ, Bendahan D, Tolfrey K, Morse CI, O'Brien TD, Reeves ND, Baltzopoulos V, Jones DA, Maganaris CN, Lambertz D, Grosset J-F, Perot C. 2011. Commentaries on Viewpoint: can muscle size fully account for strength differences between children and adults? J Appl Physiol (1985), 110 :1750-1753 >DOI >Link

O'Brien TD, Reeves ND, Baltzopoulos V, Jones DA, Maganaris CN. 2011. Quantification of human muscle specific tension in vivo: A methodologically challenging and some times impossible exercise Journal of Applied Physiology, 110 :1752-1753 >DOI

O'Brien TD, Reeves ND, Baltzopoulos V, Jones DA, Maganaris CN. 2010. In vivo measurements of muscle specific tension in adults and children Experimental Physiology, 95 :202-210 >DOI

O'Brien TD, Reeves ND, Baltzopoulos V, Jones DA, Maganaris CN. 2010. Mechanical properties of the patellar tendon in adults and children. J Biomech, 43 :1190-1195 >DOI >Link

O'Brien TD, Reeves ND, Baltzopoulos V, Jones DA, Maganaris CN. 2010. Muscle-tendon structure and dimensions in adults and children. J Anat, 216 :631-642 >DOI >Link

O'Brien TD, Reeves ND, Baltzopoulos V, Jones DA, Maganaris CN. 2009. Strong relationships exist between muscle volume, joint power and whole-body external mechanical power in adults and children. Exp Physiol, 94 :731-738 >DOI >Link

O'Brien TD, Reeves ND, Baltzopoulos V, Jones DA, Maganaris CN. 2009. The effects of agonist and antagonist muscle activation on the knee extension moment-angle relationship in adults and children. Eur J Appl Physiol, 106 :849-856 >DOI >Link

O'Brien TD, Reeves ND, Baltzopoulos V, Jones DA, Maganaris CN. 2009. Moment arms of the knee extensor mechanism in children and adults. J Anat, 215 :198-205 >DOI >Link

O'Brien TD, Reeves ND, Baltzopoulos V, Jones DA, Maganaris CN. 2008. Assessment of voluntary muscle activation using magnetic stimulation. Eur J Appl Physiol, 104 :49-55 >DOI >Link

Kalkman B, Bar-On L, Cenni F, Maganaris C, Bass A, Holmes G, Deslovere K, Barton GJ, O'Brien T. Achilles tendon moment arm length is smaller in children with cerebral palsy than in typically developing children Journal of Biomechanics,

Lemmey AB, Wilkinson T, Clayton B, Sheikh F, Whale J, Jones H, Ahmed Y, Chitale S, Jones J, Maddison PJ, O'Brien TD. Tight control of disease activity fails to improve body composition or physical function in rheumatoid arthritis patients Rheumatology,

Other

Apps C, Sterzing T, O'Brien T, Lake M. 2017. A shoe with random midsole deformations increases ankle joint variability and muscle activations during the forward lunge Footwear Science, 9 :S62-S63 >DOI

Bar-On L, Kalkman B, Cenni F, O'Brien T, Holmes G, Bass A, Barton GJ, Maganaris C, Schless S, Molenaers G, Desloovere K. 2016. Muscle and tendon properties during fast passive stretch are different in stiff and spastic muscles in children with spastic cerebral palsy Gait and Posture, 49(S2) :11-12

kalkman B, Bar-On L, Cenni F, Holmes G, Bass A, Maganaris C, Barton G, Desloovere K, O'Brien T. 2016. Passive muscle and tendon properties during ankle joint rotation in children with cerebral palsy Gait and Posture, 49(S2) :133-134

Kalkman B, Bar-On L, Cenni F, Holmes G, Bass A, Barton GJ, Maganaris C, Desloovere K, O'Brien T. 2016. The effect of cerebral palsy on Achilles tendon moment arm length Gait and Posture, 49(S2) :135-135

Editorial/letter to the editor

O'Brien TD. 2016. Musculoskeletal Proportionality, Biomechanical Considerations, and Their Contribution to Movement in Adults and Children PEDIATRIC EXERCISE SCIENCE, 28 :210-216 >DOI >Link

O'Brien TD. 2015. Biomechanics and Exercise PEDIATRIC EXERCISE SCIENCE, 27 :34-38 >DOI >Link

O'Brien TD. Commentary on: Child-Adult Differences in Muscle Activation Pediatr Exerc Sci,

Conference publication

Wilkinson TJ, Lemmey AB, Sheikh F, Ahmad Y, Chitale S, Jones J, Maddison P, O'Brien TD. 2015. CAN CREATINE SUPPLEMENTATION IMPROVE BODY COMPOSITION AND OBJECTIVE PHYSICAL FUNCTION IN RHEUMATOID ARTHRITIS PATIENTS? A RANDOMIZED CONTROLLED TRIAL RHEUMATOLOGY, Annual Meeting of the British-Society-for-Rheumatology and British-Health-Professionals-in-Rheumatology 54 :82-82 >Link

Cook RE, Mathew RG, O'Brien TD, Caine R, Jones JG, Ahmad Y, Lemmey AB. 2015. DEVELOPING AN INSTRUCTIONAL EXERCISE DVD FOR RHEUMATOID ARTHRITIS PATIENTS RHEUMATOLOGY, Annual Meeting of the British-Society-for-Rheumatology and British-Health-Professionals-in-Rheumatology 54 :144-144 >Link

Alcock L, O'Brien TD, vanicek N. 2011. The effects of healthy ageing processes on the functional measures of level gait

Pain M, O'Brien TD. 2010. Active force enhancement as a source of stretch shorten cycle enhancement? American Society of Biomechanic

Foster RJ, Kalkman BM, Ray E, Maganaris C, Barton G, Baltzopoulos V, Holmes G, Bass A, Trinca D, O'Brien T. Centre of mass control during stair descent in children with cerebral palsy European Academy of Childhood Disability

King SL, O'Brien TD, Vanicek N. Gastrocnemii structure and specific tension in claudicants with peripheral arterial disease European College of Sports Science

King S, O'Brien TD, Vanicek N. ISOMETRIC AND ISOKINETIC STRENGTH PROFILES OF CLAUDICANTS WITH PERIPHERAL ARTERIAL DISEASE European Society of Movement Analysis in Adults and Children Abstract 037 :65-65

Alcock L, O'Brien TD, Vanicek N. KNEE AND ANKLE MECHANICS DIFFERENTIATE BETWEEN THE TRANSITIONAL STEPS OF STAIR DESCENT IN OLDER WOMEN Abstract 015, European Society of Movement Analysis in Adults and Children :40-40

O'Brien TD. In vivo mechanical properties of the patellar tendon in adults and pre-pubertal children European College of Sport Sciences

Pain M, O'Brien TD. Stretch-shorten cycle enhancement decays with increased coupling time during jumping and iso-velocity knee extensions World Congress of Biomechanics

O'Brien TD. Are adult muscles intrinsically stronger than those of children? International Society of Biomechanics

Alcock L, O'Brien TD, Vanicek N. Musculoskeletal changes in gait variables associated with stair ascent in healthy older women. In the proceedings of the XXIII Congress of the International Society of Biomechanics

Engagement & Impact

Award:

Best presentaiton, BASES Biomechanics group

Experimental Physiology Early Career Author’s Prize

External collaboration:

Bangor University, Andy Lemmey

Loughborough University, Matt Pain

Brock University, Bareket Falk

University of Sydney, Natalie Vanicek

External PGR Supervision - completed students:

University of Hull, PhD

Membership of professional bodies:

Full member, International Society of Biomechanics

Other invited event:

British Society of Surgery in CP, Liverpool, Invited talk. Title: Muscle Architecture and Cerebral Palsy

Musculoskeletal system function across the lifespan: implications for improving performance and preventing injuries, Brunel University London, Invited speaker on developmental changes in muscle

Golden Horseshoe Paediatric Research Meeting, St Catherine's, Canada, Invited speaker on scaling of muscle and tendon with growth and maturation

Research Grants Awarded:

Alder Hey-LJMU match funded PhD studentship competition, Muscle responses to stretching and developing effective interventions in children with cerebral palsy, Costis Maganaris, Gabor Barton,, Grant value (£): £76,473 secured from Alder hey, Duration of research project: 3 years

Action Medical Research, The Role of Morphology and Mechanical Properties of Tendon and its Insertion in the Development of Osgood-Schlatter and Sever's Diseases, Grant value (£): 119,385

National Insitute for Social Care and Health Research, The welling, health and fitness of children with mobility impairments, Grant value (£): 208000

Betsi Cadwaldar University Health Board, Can creatine supplementation improve body composition and physical function in rheumatoid arthritis patients? A pilot randomised control trial, Grant value (£): 17,290