Dr Manlio Vinciguerra

Nursing and Allied Health

Journal article

Vinciguerra M, Dobrev D, Nattel S. 2024. Atrial fibrillation: pathophysiology, genetic and epigenetic mechanisms The Lancet Regional Health - Europe, 37 DOI Author Url Publisher Url

Chiodi V, Rappa F, Lo Re O, Chaldakov GN, Lelouvier B, Micale V, Domenici MR, Vinciguerra M. 2023. Deficiency of histone variant macroH2A1.1 is associated with sexually dimorphic obesity in mice Scientific Reports, 13 DOI Author Url Publisher Url

Tsoneva DK, Vinciguerra M. 2023. Epigenetics and companion diagnostics: opportunities and challenges Epigenomics, 15 :835-838 DOI Author Url Publisher Url

Liorni N, Napoli A, Castellana S, Giallongo S, Řeháková D, Re OL, Koutná I, Mazza T, Vinciguerra M. 2023. Integrative CUT&Tag-RNA-Seq analysis of histone variant macroH2A1-dependent orchestration of human induced pluripotent stem cell reprogramming Epigenomics, 15 :863-877 DOI Author Url Publisher Url

Ajoolabady A, Pratico D, Vinciguerra M, Lip GYH, Franceschi C, Ren J. 2023. Inflammaging: mechanisms and role in the cardiac and vasculature Trends in Endocrinology and Metabolism, 34 :373-387 DOI Author Url Publisher Url

Mainas G, Santamaria P, Ide M, Longo V, Vinciguerra M, Nart J, Nibali L. 2023. Could dietary restrictions affect periodontal disease? A systematic review Clinical Oral Investigations, DOI Author Url Publisher Url Public Url

Proietti R, Maranho Neto GA, Kunzova S, Re OL, Ahola-Olli A, Heliste J, Gonzalez-Rivas JP, Vinciguerra M. 2023. Pharmacogenomic profile of a central European urban random population-Czech population Al-Eitan L. PLoS ONE, 18 DOI Author Url Publisher Url Public Url

Proietti R, Rivera-Caravaca JM, López-Gálvez R, Harrison SL, Marín F, Underhill P, Shantsila E, McDowell G, Vinciguerra M, Davies R, Giebel C, Lane DA, Lip GYH. 2023. Cerebrovascular, Cognitive and Cardiac Benefits of SGLT2 Inhibitors Therapy in Patients with Atrial Fibrillation and Type 2 Diabetes Mellitus: Results from a Global Federated Health Network Analysis Journal of Clinical Medicine, 12 DOI Author Url Publisher Url Public Url

Sanfilippo C, Castrogiovanni P, Vinciguerra M, Imbesi R, Ulivieri M, Fazio F, Cantarella A, Nunnari G, Di Rosa M. 2023. Neuro-immune deconvolution analysis of OAS3 as a transcriptomic central node in HIV-associated neurocognitive disorders Journal of the Neurological Sciences, 446 DOI Author Url Publisher Url

Sanfilippo C, Castrogiovanni P, Vinciguerra M, Imbesi R, Ulivieri M, Fazio F, Blennow K, Zetterberg H, Di Rosa M. 2023. A sex-stratified analysis of neuroimmune gene expression signatures in Alzheimer’s disease brains GeroScience, 45 :523-541 DOI Author Url Publisher Url

Tsoneva DK, Ivanov MN, Conev NV, Manev R, Stoyanov DS, Vinciguerra M. 2023. Circulating Histones to Detect and Monitor the Progression of Cancer International Journal of Molecular Sciences, 24 DOI Author Url Publisher Url Public Url

Buzova D, Frohlich J, Zapletalova D, Raffaele M, Lo Re O, Tsoneva DK, Sterba J, Cerveny J, Vinciguerra M. 2023. Detection of cell-free histones in the cerebrospinal fluid of pediatric central nervous system malignancies by imaging flow cytometry Frontiers in Molecular Biosciences, 10 DOI Author Url Publisher Url

Tsoneva DK, Ivanov MN, Vinciguerra M. 2023. Liquid Liver Biopsy for Disease Diagnosis and Prognosis Journal of Clinical and Translational Hepatology, 11 :1520-1541 DOI Author Url Publisher Url

Vinciguerra M, Olier I, Ortega-Martorell S, Lip GYH. 2022. New use for an old drug: Metformin and atrial fibrillation. Cell reports. Medicine, 3 DOI Author Url Publisher Url Public Url

Frohlich J, Raffaele M, Skalova H, Leire E, Pata I, Pata P, Gorbunova V, Vinciguerra M. 2022. Human centenarian-associated SIRT6 mutants modulate hepatocyte metabolism and collagen deposition in multilineage hepatic 3D spheroids. Geroscience, DOI Author Url Publisher Url Public Url

Braghini MR, Lo Re O, Romito I, Fernandez-Barrena MG, Barbaro B, Pomella S, Rota R, Vinciguerra M, Avila MA, Alisi A. 2022. Epigenetic remodelling in human hepatocellular carcinoma Journal of Experimental and Clinical Cancer Research, 41 DOI Author Url Publisher Url

Vinciguerra M. 2022. Profiling of cell-free DNA methylation and histone signatures in pediatric NAFLD: A pilot study Hepatology Communications, 6 :3311-3323 DOI Author Url Publisher Url Public Url

Frohlich J, Kovacovicova K, Raffaele M, Virglova T, Cizkova E, Kucera J, Bienertova-Vasku J, Wabitsch M, Peyrou M, Bonomini F, Rezzani R, Chaldakov GN, Tonchev AB, Di Rosa M, Blavet N, Hejret V, Vinciguerra M. 2022. GDF11 inhibits adipogenesis and improves mature adipocytes metabolic function via WNT/β-catenin and ALK5/SMAD2/3 pathways Cell Proliferation, 55 DOI Author Url Publisher Url

Vinciguerra M. 2022. Telomere oxidative lesions and cell senescence Nature Aging, 2 :690 DOI Publisher Url

Menghini R, Hoyles L, Cardellini M, Casagrande V, Marino A, Gentileschi P, Davato F, Mavilio M, Arisi I, Mauriello A, Montanaro M, Scimeca M, Barton RH, Rappa F, Cappello F, Vinciguerra M, Moreno-Navarrete JM, Ricart W, Porzio O, Fernández-Real JM, Burcelin R, Dumas ME, Federici M. 2022. ITCH E3 ubiquitin ligase downregulation compromises hepatic degradation of branched-chain amino acids Molecular Metabolism, 59 DOI Author Url Publisher Url

Vinciguerra M. 2022. Blocking eicosanoid signalling prevents severe COVID-19 Nature Aging, 2 :369 DOI Publisher Url

Vinciguerra M. 2022. Flawed translation leads to premature aging Nature Aging, 2 :276 DOI Publisher Url

Giallongo S, Řeháková D, Biagini T, Lo Re O, Raina P, Lochmanová G, Zdráhal Z, Resnick I, Pata P, Pata I, Mistrík M, De Magalhães JP, Mazza T, Koutná I, Vinciguerra M. 2022. Histone Variant macroH2A1.1 Enhances Nonhomologous End Joining-dependent DNA Double-strand-break Repair and Reprogramming Efficiency of Human iPSCs Stem Cells, 40 :35-48 DOI Publisher Url

Raffaele M, Kovacovicova K, Biagini T, Lo Re O, Frohlich J, Giallongo S, Nhan JD, Giannone AG, Cabibi D, Ivanov M, Tonchev AB, Mistrik M, Lacey M, Dzubak P, Gurska S, Hajduch M, Bartek J, Mazza T, Micale V, Curran SP, Vinciguerra M. 2022. Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects GeroScience, 44 :463-483 DOI Author Url Publisher Url

Raffaele M, Vinciguerra M. 2022. The costs and benefits of senotherapeutics for human health The Lancet. Healthy Longevity, 3 :e67-e77 DOI Publisher Url Public Url

Vinciguerra M. 2022. Urolithin A improves physical performance in middle age Nature Aging, DOI Publisher Url

Raffaele M, Kovacovicova K, Frohlich J, Lo Re O, Giallongo S, Oben JA, Faldyna M, Leva L, Giannone AG, Cabibi D, Vinciguerra M. 2021. Mild exacerbation of obesity- and age-dependent liver disease progression by senolytic cocktail dasatinib + quercetin Cell Communication and Signaling, 19 DOI Author Url Publisher Url

Romito I, Porru M, Braghini MR, Pompili L, Panera N, Crudele A, Gnani D, De Stefanis C, Scarsella M, Pomella S, Levi Mortera S, de Billy E, Conti AL, Marzano V, Putignani L, Vinciguerra M, Balsano C, Pastore A, Rota R, Tartaglia M, Leonetti C, Alisi A. 2021. Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects Journal of Experimental and Clinical Cancer Research, 40 DOI Author Url Publisher Url

Rivas Serna IM, Sitina M, Stokin GB, Medina-Inojosa JR, Lopez-Jimenez F, Gonzalez-Rivas JP, Vinciguerra M. 2021. Lipidomic profiling identifies signatures of poor cardiovascular health Metabolites, 11 DOI Author Url Publisher Url

Cabibi D, Napolitano C, Giannone AG, Micciulla MC, Porcasi R, Coco RL, Bosco L, Vinciguerra M, Capra G. 2021. Predictive role of the p16 immunostaining pattern in atypical cervical biopsies with less common high risk hpv genotypes Diagnostics, 11 DOI Author Url Publisher Url

Mishra A, Mirzaei H, Guidi N, Vinciguerra M, Mouton A, Linardic M, Rappa F, Barone R, Navarrete G, Wei M, Brandhorst S, Di Biase S, Morgan TE, Ram Kumar S, Conti PS, Pellegrini M, Bernier M, de Cabo R, Longo VD. 2021. Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan Nature Metabolism, 3 :1342-1356 DOI Author Url Publisher Url

Chiodi V, Domenici MR, Biagini T, De Simone R, Tartaglione AM, Di Rosa M, Lo Re O, Mazza T, Micale V, Vinciguerra M. 2021. Systemic depletion of histone macroH2A1.1 boosts hippocampal synaptic plasticity and social behavior in mice FASEB Journal, 35 DOI Author Url Publisher Url

Crudele A, Dato S, Re OL, Maugeri A, Sanna P, Giallongo S, Oben J, Panera N, De Rango F, Mosca A, Rose G, Passarino G, Alisi A, Vinciguerra M. 2021. Pediatric Non-Alcoholic Fatty Liver Disease Is Affected by Genetic Variants Involved in Lifespan/Healthspan Journal of Pediatric Gastroenterology and Nutrition, 73 :161-168 DOI Author Url Publisher Url Public Url

Giallongo S, Lo Re O, Lochmanová G, Parca L, Petrizzelli F, Zdráhal Z, Mazza T, Vinciguerra M. 2021. Phosphorylation within intrinsic disordered region discriminates histone variant macroh2a1 splicing isoforms—macroh2a1.1 and macroh2a1.2 Biology, 10 DOI Author Url Publisher Url

Sanfilippo C, Castrogiovanni P, Imbesi R, Lazzarino G, Di Pietro V, Li Volti G, Tibullo D, Barbagallo I, Lazzarino G, Avola R, Musumeci G, Fazio F, Vinciguerra M, Di Rosa M. 2021. Sex-dependent monoamine oxidase isoforms expression patterns during human brain ageing Mechanisms of Ageing and Development, 197 DOI Author Url Publisher Url

Frohlich J, Mazza T, Sobolewski C, Foti M, Vinciguerra M. 2021. GDF11 rapidly increases lipid accumulation in liver cancer cells through ALK5-dependent signaling Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1866 DOI Author Url Publisher Url

Frohlich J, Chaldakov GN, Vinciguerra M. 2021. Cardio-and neurometabolic adipobiology: Consequences and implications for therapy International Journal of Molecular Sciences, 22 DOI Author Url Publisher Url

Vasile VC, Meeusen JW, Medina Inojosa JR, Donato LJ, Scott CG, Hyun MS, Vinciguerra M, Rodeheffer RR, Lopez-Jimenez F, Jaffe AS. 2021. Ceramide Scores Predict Cardiovascular Risk in the Community Arteriosclerosis, Thrombosis and Vascular Biology, 41 :1558-1569 DOI Author Url Publisher Url

Giallongo S, Rehakova D, Raffaele M, Lo Re O, Koutna I, Vinciguerra M. 2021. Redox and Epigenetics in Human Pluripotent Stem Cells Differentiation Antioxidants and Redox Signaling, 34 :335-349 DOI Author Url Publisher Url

Auffray C, Balling R, Blomberg N, Bonaldo MC, Boutron B, Brahmachari S, Bréchot C, Cesario A, Chen SJ, Clément K, Danilenko D, Meglio AD, Gelemanović A, Goble C, Gojobori T, Goldman JD, Goldman M, Guo YK, Heath J, Hood L, Hunter P, Jin L, Kitano H, Knoppers B, Lancet D, Larue C, Lathrop M, Laville M, Lindner AB, Magnan A, Metspalu A, Morin E, Ng LFP, Nicod L, Noble D, Nottale L, Nowotny H, Ochoa T, Okeke IN, Oni T, Openshaw P, Oztürk M, Palkonen S, Paweska JT, Pison C, Polymeropoulos MH, Pristipino C, Protzer U, Roca J, Rozman D, Santolini M, Sanz F, Scambia G, Segal E, Serageldin I, Soares MB, Sterk P, Sugano S, Superti-Furga G, Supple D, Tegner J, Uhlen M, Urbani A, Valencia A, Valentini V, van der Werf S, Vinciguerra M, Wolkenhauer O, Wouters E. 2021. COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight F1000Research, 9 :1-18 DOI Publisher Url

Frohlich J, Vinciguerra M. 2020. Candidate rejuvenating factor GDF11 and tissue fibrosis: friend or foe? GeroScience, 42 :1475-1498 DOI Author Url Publisher Url

Serna IMR, Romito I, Maugeri A, Re OL, Giallongo S, Mazzoccoli G, Oben JA, Volti GL, Mazza T, Alisi A, Vinciguerra M. 2020. A lipidomic signature complements stemness features acquisition in liver cancer cells International Journal of Molecular Sciences, 21 :1-18 DOI Author Url Publisher Url

Vinciguerra M, Masotti A, Alisi A. 2020. Editorial: Role of Epigenetic Modifications on Diet-Induced Metabolic Diseases Frontiers in Genetics, 11 DOI Publisher Url

Maugeri A, Hlinomaz O, Agodi A, Barchitta M, Kunzova S, Bauerova H, Sochor O, Medina-Inojosa JR, Lopez-Jimenez F, Vinciguerra M, Stokin GB, González-Rivas JP. 2020. Is drinking alcohol really linked to cardiovascular health? Evidence from the kardiovize 2030 project Nutrients, 12 :1-12 DOI Author Url Publisher Url

Buzova D, Maugeri A, Liguori A, Napodano C, Lo Re O, Oben J, Alisi A, Gasbarrini A, Grieco A, Cerveny J, Miele L, Vinciguerra M. 2020. Circulating histone signature of human lean metabolic-associated fatty liver disease (MAFLD) Clinical Epigenetics, 12 DOI Author Url Publisher Url

Raffaele M, Kovacovicova K, Bonomini F, Rezzani R, Frohlich J, Vinciguerra M. 2020. Senescence-like phenotype in post-mitotic cells of mice entering middle age Aging, 12 :13979-13990 DOI Author Url Publisher Url

Maugeri A, Barchitta M, Kunzova S, Bauerova H, Agodi A, Vinciguerra M. 2020. The association of social and behavioral factors with dietary risks in adults: Evidence from the Kardiovize Brno 2030 study Nutrition, Metabolism and Cardiovascular Diseases, 30 :896-906 DOI Author Url Publisher Url

Giallongo S, Di Rosa M, Caltabiano R, Longhitano L, Reibaldi M, Distefano A, Re OL, Amorini AM, Puzzo L, Salvatorelli L, Palmucci S, Tibullo D, Russo A, Longo A, Lazzarino G, Li Volti G, Vinciguerra M. 2020. Loss of macroH2A1 decreases mitochondrial metabolism and reduces the aggressiveness of uveal melanoma cells Aging, 12 :9745-9760 DOI Author Url Publisher Url

Calimport SRG, Bentley BL, Stewart CE, Pawelec G, Scuteri A, Vinciguerra M, Slack C, Chen D, Harries LW, Marchant G, Alexander Fleming G, Conboy M, Antebi A, Small GW, Gil J, Lakatta EG, Richardson A, Rosen C, Nikolich K, Wyss-Coray T, Steinman L, Montine T, de Magalhães JP, Campisi J, Church G. 2020. The inherent challenges of classifying senescence−−Response Science, 368 :595-596 DOI Author Url Publisher Url

Robinson EL, da Costa Gomes CP, Potočnjak I, Hellemans J, Betsou F, de Gonzalo-Calvo D, Stoll M, Yilmaz MB, Ágg B, Beis D, Carmo-Fonseca M, Enguita FJ, Dogan S, Tuna BG, Schroen B, Ammerlaan W, Kuster GM, Carpusca I, Pedrazzini T, Emanueli C, Martelli F, Devaux Y, Acharya S, Aghagolzadeh P, Albinsson S, Allaer D, Andova A, Angione C, Arnal JF, Arslan S, Lustrek M, Maegdefessel L, Marchese M, Martino F, Mazzanti C, Meli A, Tonczar JM, Murri M, Niculescu LS, Backs J, Nielsen N, Nossent AY, Novella S, Novokmet N, O'brien T, Oliveira C, Orbe J, Paes A, Papaneophytou C, Badimon L, Perez-Pomares J, Pinet F, Popescu O, Potocnjak I, Rizanov A, Ruberto F, Pipaon GS, Sahoo S, Baker A, Somoza AS, Sanchez-Madrid F, Sasson S, Scholz M, Semenovykh D, Simionescu M, Soares A, Sopic M, Sorensen A, Barbalata T, Spinetti G, Squire I, Srivastava P, Stancu CS, Benic MS, Stefanizzi FM, Steffens S, Stellos K, Thum T, Barbosa P, Tikhomirov R, Toledo M, Trbusic M, Chalot S, Turkieh A, Van Der Bent ML, Ingen EV, Rooij EV, Vanhaverbeke M, Varga Z, Bartekova M, Verjans R, Vilahur G, Vinciguerra M, Vindis C, Wac K, Whittaker A, Xuereb A, Zangi L, Zhang L, Bashiardes E. 2020. A year in the life of the EU-CardioRNA COST action: CA17129 catalysing transcriptomics research in cardiovascular disease Non-coding RNA, 6 DOI Publisher Url

Kunzova S, Maugeri A, Medina-Inojosa J, Lopez-Jimenez F, Vinciguerra M, Marques-Vidal P. 2020. Determinants of Metabolic Health Across Body Mass Index Categories in Central Europe: A Comparison Between Swiss and Czech Populations Frontiers in Public Health, 8 DOI Publisher Url

Medina-Inojosa JR, Vinciguerra M, Maugeri A, Kunzova S, Sochor O, Movsisyan N, Geda YE, Stokin GB, Lopez-Jimenez F. 2020. Prevalence of ideal cardiovascular health in a Central European community: results from the Kardiovize Brno 2030 Project European Journal of Preventive Cardiology, 27 :441-443 DOI Author Url Publisher Url

Mazzoccoli G, Vinciguerra M, Carbone A, Relógio A. 2020. The circadian clock, the immune system, and viral infections: The intricate relationship between biological time and host-virus interaction Pathogens, 9 DOI Author Url Publisher Url

Maugeri A, Vinciguerra M. 2020. The effects of meal timing and frequency, caloric restriction, and fasting on cardiovascular health: An overview Journal of Lipid and Atherosclerosis, 9 :140-152 DOI Author Url Publisher Url

Lo Re O, Mazza T, Giallongo S, Sanna P, Rappa F, Luong TV, Li Volti G, Drovakova A, Roskams T, van Haele M, Tsochatzis E, Vinciguerra M. 2020. Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+FoxP3+ regulatory T cells activation Theranostics, 10 :910-924 DOI Author Url Publisher Url

Movsisyan NK, Vinciguerra M, Medina-Inojosa JR, Lopez-Jimenez F. 2020. Cardiovascular diseases in central and Eastern Europe: A call for more surveillance and evidence-based health promotion Annals of Global Health, 86 DOI Author Url Publisher Url

Frohlich J, Kovacovicova K, Mazza T, Emma MR, Cabibi D, Foti M, Sobolewski C, Oben JA, Peyrou M, Villarroya F, Soresi M, Rezzani R, Cervello M, Bonomini F, Alisi A, Vinciguerra M. 2020. GDF11 induces mild hepatic fibrosis independent of metabolic health Aging, 12 :20024-20039 DOI Author Url Publisher Url

Lo Re O, Maugeri A, Hruskova J, Jakubik J, Kucera J, Bienertova-Vasku J, Oben JA, Kubala L, Dvorakova A, Ciz M, Vinciguerra M. 2019. Obesity-induced nucleosome release predicts poor cardio-metabolic health Clinical Epigenetics, 12 DOI Author Url Publisher Url

Maugeri A, Hruskova J, Jakubik J, Hlinomaz O, Medina-Inojosa JR, Barchitta M, Agodi A, Vinciguerra M. 2019. How dietary patterns affect left ventricular structure, function and remodelling: evidence from the Kardiovize Brno 2030 study Scientific Reports, 9 DOI Author Url Publisher Url

Kovacovicova K, Vinciguerra M. 2019. Isolation of senescent cells by iodixanol (OptiPrep) density gradient-based separation Cell Proliferation, 52 DOI Author Url Publisher Url

Mazzoccoli G, Miele L, Marrone G, Mazza T, Vinciguerra M, Grieco A. 2019. A role for the biological clock in liver cancer Cancers, 11 DOI Publisher Url

Saeidifard F, Medina-Inojosa JR, West CP, Olson TP, Somers VK, Bonikowske AR, Prokop LJ, Vinciguerra M, Lopez-Jimenez F. 2019. The association of resistance training with mortality: A systematic review and meta-analysis European Journal of Preventive Cardiology, 26 :1647-1665 DOI Author Url Publisher Url

Bereshchenko O, Lo Re O, Nikulenkov F, Flamini S, Kotaskova J, Mazza T, Le Pannérer MM, Buschbeck M, Giallongo C, Palumbo G, Li Volti G, Pazienza V, Cervinek L, Riccardi C, Krejci L, Pospisilova S, Stewart AF, Vinciguerra M. 2019. Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome Clinical Epigenetics, 11 DOI Author Url Publisher Url

Salvatorelli L, Puzzo L, Bartoloni G, Palmucci S, Longo A, Russo A, Reibaldi M, Vinciguerra M, Li Volti G, Caltabiano R. 2019. Immunoexpression of macroH2A in uveal melanoma Applied Sciences (Switzerland), 9 DOI Publisher Url

Mazzoccoli G, Keshavarzian A, Vinciguerra M. 2019. Hedgehog signaling keeps liver clock in check Journal of Hepatology, 70 :1054-1056 DOI Author Url Publisher Url

Giallongo S, Re OL, Vinciguerra M. 2019. Macro histone variants: Emerging rheostats of gastrointestinal cancers Cancers, 11 DOI Publisher Url

Maugeri A, Hruskova J, Jakubik J, Barchitta M, Re OL, Kunzova S, Medina-Inojosa JR, Agodi A, Sciacca S, Vinciguerra M. 2019. Independent effects of hypertension and obesity on left ventricular mass and geometry: Evidence from the cardiovision 2030 study Journal of Clinical Medicine, 8 DOI Publisher Url

Maugeri A, Hruskova J, Jakubik J, Kunzova S, Sochor O, Barchitta M, Agodi A, Bauerova H, Medina-Inojosa JR, Vinciguerra M. 2019. Dietary antioxidant intake decreases carotid intima media thickness in women but not in men: A cross-sectional assessment in the Kardiovize study Free Radical Biology and Medicine, 131 :274-281 DOI Author Url Publisher Url

Vinciguerra S, Vinciguerra M. 2019. Smart devices and healthy aging Nutrition and Healthy Aging, 5 :13-19 DOI Publisher Url

da Costa Gomes CP, Ágg B, Andova A, Arslan S, Baker A, Barteková M, Beis D, Betsou F, Wettinger SB, Bugarski B, Condorelli G, da Silva GJJ, Danilin S, de Gonzalo-Calvo D, Buil A, Carmo-Fonseca M, Enguita FJ, Felekkis K, Ferdinandy P, Gyöngyösi M, Hackl M, Karaduzovic-Hadziabdic K, Hellemans J, Heymans S, Hlavackova M, Hoydal MA, Jankovic A, Jusic A, Kardassis D, Kerkelä R, Kuster GM, Lakkisto P, Leszek P, Lustrek M, Maegdefessel L, Martelli F, Novella S, O'Brien T, Papaneophytou C, Pedrazzini T, Pinet F, Popescu O, Potočnjak I, Robinson E, Sasson S, Scholz M, Simionescu M, Stoll M, Varga ZV, Vinciguerra M, Xuereb A, Yilmaz MB, Emanueli C, Devaux Y. 2019. Catalyzing transcriptomics research in cardiovascular disease: The CardioRNA COST action CA17129 Non-coding RNA, 5 DOI Publisher Url

Lo Re O, Mazza T, Vinciguerra M. 2018. Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults Frontiers in Genetics, 9 DOI Publisher Url

Maugeri A, Medina-Inojosa JR, Kunzova S, Agodi A, Barchitta M, Sochor O, Lopez-Jimenez F, Geda YE, Vinciguerra M. 2018. Sleep duration and excessive daytime sleepiness are associated with obesity independent of diet and physical activity Nutrients, 10 DOI Author Url Publisher Url

Lo Re O, Douet J, Buschbeck M, Fusilli C, Pazienza V, Panebianco C, Castracani CC, Mazza T, Li Volti G, Vinciguerra M. 2018. Histone variant macroH2A1 rewires carbohydrate and lipid metabolism of hepatocellular carcinoma cells towards cancer stem cells Epigenetics, 13 :829-845 DOI Author Url Publisher Url

Maugeri A, Kunzova S, Medina-Inojosa JR, Agodi A, Barchitta M, Homolka M, Kiacova N, Bauerova H, Sochor O, Lopez-Jimenez F, Vinciguerra M. 2018. Association between eating time interval and frequency with ideal cardiovascular health: Results from a random sample Czech urban population Nutrition, Metabolism and Cardiovascular Diseases, 28 :847-855 DOI Author Url Publisher Url

Agodi A, Maugeri A, Kunzova S, Sochor O, Bauerova H, Kiacova N, Barchitta M, Vinciguerra M. 2018. Association of dietary patterns with metabolic syndrome: Results from the kardiovize brno 2030 study Nutrients, 10 DOI Author Url Publisher Url

Hruskova J, Maugeri A, Podroužková H, Štípalová T, Jakubík J, Barchitta M, Medina-Inojosa JR, Homolka M, Agodi A, Kunzova S, Sochor O, Lopez-Jimenez F, Vinciguerra M. 2018. Association of cardiovascular health with epicardial adipose tissue and intima media thickness: The Kardiovize study Journal of Clinical Medicine, 7 DOI Publisher Url

Lo Re O, Panebianco C, Porto S, Cervi C, Rappa F, Di Biase S, Caraglia M, Pazienza V, Vinciguerra M. 2018. Fasting inhibits hepatic stellate cells activation and potentiates anti-cancer activity of Sorafenib in hepatocellular cancer cells Journal of Cellular Physiology, 233 :1202-1212 DOI Author Url Publisher Url

Lo Re O, Fusilli C, Rappa F, Van Haele M, Douet J, Pindjakova J, Rocha SW, Pata I, Valčíková B, Uldrijan S, Yeung RS, Peixoto CA, Roskams T, Buschbeck M, Mazza T, Vinciguerra M. 2018. Induction of cancer cell stemness by depletion of macrohistone H2A1 in hepatocellular carcinoma Hepatology, 67 :636-650 DOI Author Url Publisher Url

Maugeri A, Oben JA, Vinciguerra M. 2018. Protein-Rich or Amino-Acid Only Diets Entrain the Liver Clock: Time to Scrap Insulin? EBioMedicine, 28 :9-10 DOI Author Url Publisher Url

Bienertova-Vasku J, Vinciguerra M, Buzga M, Villaroya F. 2018. Adipokines as biomarkers in health and disease Disease Markers, 2018 DOI Author Url Publisher Url

Maugeri A, Mazzone MG, Giuliano F, Vinciguerra M, Basile G, Barchitta M, Agodi A. 2018. Curcumin Modulates DNA Methyltransferase Functions in a Cellular Model of Diabetic Retinopathy Oxidative Medicine and Cellular Longevity, 2018 DOI Author Url Publisher Url

Movsisyan NK, Vinciguerra M, Lopez-Jimenez F, Kunzová Š, Homolka M, Jaresova J, Cífková R, Sochor O. 2018. Kardiovize Brno 2030, a prospective cardiovascular health study in central Europe: Methods, baseline findings and future directions European Journal of Preventive Cardiology, 25 :54-64 DOI Author Url Publisher Url

Kovacovicova K, Skolnaja M, Heinmaa M, Mistrik M, Pata P, Pata I, Bartek J, Vinciguerra M. 2018. Senolytic cocktail dasatinib+quercetin (D+Q) does not enhance the efficacy of senescence-inducing chemotherapy in liver cancer Frontiers in Oncology, 8 DOI Publisher Url

Re OL, Vinciguerra M. 2017. Histone macroH2A1: A chromatin point of intersection between fasting, senescence and cellular regeneration Genes, 8 DOI Publisher Url

Cordero P, Li J, Nguyen V, Pombo J, Maicas N, Novelli M, Taylor PD, Samuelsson AM, Vinciguerra M, Oben JA. 2017. Developmental programming of obesity and liver metabolism by maternal perinatal nutrition involves the melanocortin system Nutrients, 9 DOI Author Url Publisher Url

Panebianco C, Oben JA, Vinciguerra M, Pazienza V. 2017. Senescence in hepatic stellate cells as a mechanism of liver fibrosis reversal: a putative synergy between retinoic acid and PPAR-gamma signalings Clinical and Experimental Medicine, 17 :269-280 DOI Author Url Publisher Url

Pindjakova J, Sartini C, Re OL, Rappa F, Coupe B, Lelouvier B, Pazienza V, Vinciguerra M. 2017. Gut dysbiosis and adaptive immune response in diet-induced obesity vs. Systemic inflammation Frontiers in Microbiology, 8 DOI Author Url Publisher Url

Volti GL, Avola R, Vinciguerra M. 2017. Commentary: Fasting-mimicking diet reduces HO-1 to promote T cell-mediated tumor cytotoxicity Frontiers in Oncology, 7 DOI Author Url Publisher Url

Soeda J, Cordero P, Li J, Mouralidarane A, Asilmaz E, Ray S, Nguyen V, Carter R, Novelli M, Vinciguerra M, Poston L, Taylor PD, Oben JA. 2017. Hepatic rhythmicity of endoplasmic reticulum stress is disrupted in perinatal and adult mice models of high-fat diet-induced obesity International Journal of Food Sciences and Nutrition, 68 :455-466 DOI Author Url Publisher Url

Di Biase S, Shim HS, Kim KH, Vinciguerra M, Rappa F, Wei M, Brandhorst S, Cappello F, Mirzaei H, Lee C, Longo VD. 2017. Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy PLoS Biology, 15 DOI Author Url Publisher Url

Bellanti F, Iannelli G, Blonda M, Tamborra R, Villani R, Romano A, Calcagnini S, Mazzoccoli G, Vinciguerra M, Gaetani S, Giudetti AM, Vendemiale G, Cassano T, Serviddio G. 2017. Alterations of Clock Gene RNA Expression in Brain Regions of a Triple Transgenic Model of Alzheimer's Disease Journal of Alzheimer's Disease, 59 :615-631 DOI Author Url Publisher Url

Pazienza V, Panebianco C, Rappa F, Memoli D, Borghesan M, Cannito S, Oji A, Mazza G, Tamburrino D, Fusai G, Barone R, Bolasco G, Villarroya F, Villarroya J, Hatsuzawa K, Cappello F, Tarallo R, Nakanishi T, Vinciguerra M. 2016. Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis Epigenetics and Chromatin, 9 :1-19 DOI Author Url Publisher Url

Burhan I, Furini G, Lortat-Jacob H, Atobatele AG, Scarpellini A, Schroeder N, Atkinson J, Maamra M, Nutter FH, Watson P, Vinciguerra M, Johnson TS, Verderio EAM. 2016. Interplay between transglutaminases and heparan sulphate in progressive renal scarring Scientific Reports, 6 DOI Author Url Publisher Url

Jueliger S, Lyons J, Cannito S, Pata I, Pata P, Shkolnaya M, Lo Re O, Peyrou M, Villarroya F, Pazienza V, Rappa F, Cappello F, Azab M, Taverna P, Vinciguerra M. 2016. Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma Epigenetics, 11 :709-720 DOI Author Url Publisher Url

Mazzoccoli G, Tarquini R, Valoriani A, Oben J, Vinciguerra M, Marra F. 2016. Management strategies for hepatocellular carcinoma: old certainties and new realities Clinical and Experimental Medicine, 16 :243-256 DOI Author Url Publisher Url

Soeda J, Mouralidarane A, Cordero P, Li J, Nguyen V, Carter R, Kapur SR, Pombo J, Poston L, Taylor PD, Vinciguerra M, Oben JA. 2016. Maternal obesity alters endoplasmic reticulum homeostasis in offspring pancreas Journal of Physiology and Biochemistry, 72 :281-291 DOI Author Url Publisher Url

Mazzoccoli G, Miele L, Oben J, Grieco A, Vinciguerra M. 2016. Biology, Epidemiology, Clinical aspects of hepatocellular Carcinoma and the role of Sorafenib Current Drug Targets, 17 :783-799 DOI Author Url Publisher Url

Vinciguerra M, Mazzoccoli G. 2016. Aryl hydrocarbon receptor-fibroblast growth factor 21 dissociation of fatty liver from insulin resistance: A timely matter? Hepatology, 63 :1396-1397 DOI Author Url Publisher Url

Mazzoccoli G, Rubino R, Tiberio C, Giuliani F, Vinciguerra M, Oben J, De Cata A, Tarquini R, De Cosmo S, Liu S, Cai Y. 2016. Clock gene expression in human and mouse hepatic models shows similar periodicity but different dynamics of variation Chronobiology International, 33 :181-190 DOI Author Url Publisher Url

Morgan ML, Sigala B, Soeda J, Cordero P, Nguyen V, Mckee C, Mouraliderane A, Vinciguerra M, Oben JA. 2016. Acetylcholine induces fibrogenic effects via M2/M3 acetylcholine receptors in non-alcoholic steatohepatitis and in primary human hepatic stellate cells Journal of Gastroenterology and Hepatology (Australia), 31 :475-483 DOI Author Url Publisher Url

Borghesan M, Fusilli C, Rappa F, Panebianco C, Rizzo G, Oben JA, Mazzoccoli G, Faulkes C, Pata I, Agodi A, Rezaee F, Minogue S, Warren A, Peterson A, Sedivy JM, Douet J, Buschbeck M, Cappello F, Mazza T, Pazienza V, Vinciguerra M. 2016. DNA Hypomethylation and histone variant macroH2A1 synergistically attenuate chemotherapy-induced senescence to promote hepatocellular carcinoma progression Cancer Research, 76 :594-606 DOI Author Url Publisher Url

Mazzoccoli G, Colangelo T, Panza A, Rubino R, De Cata A, Tiberio C, Valvano MR, Pazienza V, Merla G, Augello B, Trombetta D, Storlazzi CT, Macchia G, Gentile A, Tavano F, Vinciguerra M, Bisceglia G, Rosato V, Colantuoni V, Sabatino L, Piepoli A. 2016. Deregulated expression of cryptochrome genes in human colorectal cancer Molecular Cancer, 15 DOI Author Url Publisher Url

Balasus D, Way M, Fusilli C, Mazza T, Morgan MY, Cervello M, Giannitrapani L, Soresi M, Agliastro R, Vinciguerra M, Montalto G. 2016. The association of variants in PNPLA3 and GRP78 and the risk of developing hepatocellular carcinoma in an Italian population Oncotarget, 7 :86791-86802 DOI Author Url Publisher Url

Mazzoccoli G, Laukkanen MO, Vinciguerra M, Colangelo T, Colantuoni V. 2016. A Timeless Link Between Circadian Patterns and Disease Trends in Molecular Medicine, 22 :68-81 DOI Author Url Publisher Url

Re OL, Vinciguerra M. 2016. Macrohistone H2A1 takes the center stage in cancer research as a regulator of stemness Translational Cancer Research, 5 :S747-S750 DOI Publisher Url

Rahimi M, Ng EP, Bakhtiari K, Vinciguerra M, Ahmad HA, Awala H, Mintova S, Daghighi M, Bakhshandeh Rostami F, De Vries M, Motazacker MM, Peppelenbosch MP, Mahmoudi M, Rezaee F. 2015. Zeolite Nanoparticles for Selective Sorption of Plasma Proteins Scientific Reports, 5 DOI Author Url Publisher Url

Demolli S, Doebele C, Doddaballapur A, Lang V, Fisslthaler B, Chavakis E, Vinciguerra M, Sciacca S, Henschler R, Hecker M, Savant S, Augustin HG, Kaluza D, Dimmeler S, Boon RA. 2015. MicroRNA-30 mediates anti-inflammatory effects of shear stress and KLF2 via repression of angiopoietin 2 Journal of Molecular and Cellular Cardiology, 88 :111-119 DOI Author Url Publisher Url

Agodi A, Barchitta M, Quattrocchi A, Maugeri A, Canto C, Marchese AE, Vinciguerra M. 2015. Low fruit consumption and folate deficiency are associated with LINE-1 hypomethylation in women of a cancer-free population Genes and Nutrition, 10 DOI Author Url Publisher Url

Mouralidarane A, Soeda J, Sugden D, Bocianowska A, Carter R, Ray S, Saraswati R, Cordero P, Novelli M, Fusai G, Vinciguerra M, Poston L, Taylor PD, Oben JA. 2015. Maternal obesity programs offspring non-alcoholic fatty liver disease through disruption of 24-h rhythms in mice International Journal of Obesity, 39 :1339-1348 DOI Author Url Publisher Url

Agodi A, Barchitta M, Quattrocchi A, Maugeri A, Vinciguerra M. 2015. DAPK1 promoter methylation and cervical cancer risk: A systematic review and a meta-analysis PLoS ONE, 10 DOI Author Url Publisher Url

Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, De Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y, Vijg J, Vinciguerra M, Fontana L. 2015. Interventions to slow aging in humans: Are we ready? Aging Cell, 14 :497-510 DOI Author Url Publisher Url

Brandhorst S, Choi IY, Wei M, Cheng CW, Sedrakyan S, Navarrete G, Dubeau L, Yap LP, Park R, Vinciguerra M, Di Biase S, Mirzaei H, Mirisola MG, Childress P, Ji L, Groshen S, Penna F, Odetti P, Perin L, Conti PS, Ikeno Y, Kennedy BK, Cohen P, Morgan TE, Dorff TB, Longo VD. 2015. A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan Cell Metabolism, 22 :86-99 DOI Author Url Publisher Url

Vinciguerra M. 2015. Nitric oxide as a protector from nonalcoholic fatty liver disease Hepatology, 61 :2115-2116 DOI Author Url Publisher Url

Podrini C, Koffas A, Choksh S, Vinciguerra M, Lelliott CJ, White JK, Adissu HA, Williams R, Greco A. 2015. MacroH2A1 isoforms are associated with epigenetic markers for activation of lipogenic genes in fat-induced steatosis FASEB Journal, 29 :1676-1687 DOI Author Url Publisher Url

Mazza T, Fusilli C, Saracino C, Mazzoccoli G, Tavano F, Vinciguerra M, Pazienza V. 2015. Functional impact of autophagy-related genes on the homeostasis and dynamics of pancreatic cancer cell lines IEEE/ACM Transactions on Computational Biology and Bioinformatics, 12 :667-678 DOI Author Url Publisher Url

Tavano F, Pazienza V, Fontana A, Burbaci FP, Panebianco C, Saracino C, Lombardi L, De Bonis A, Di Mola FF, Di Sebastiano P, Piepoli A, Vinciguerra M, Fracavilla M, Giuliani F, Rubino R, Andriulli A, Mazzoccoli G. 2015. SIRT1 and circadian gene expression in pancreatic ductal adenocarcinoma: Effect of starvation Chronobiology International, 32 :497-512 DOI Author Url Publisher Url

Sheedfar F, Vermeer M, Pazienza V, Villarroya J, Rappa F, Cappello F, Mazzoccoli G, Villarroya F, Van Der Molen H, Hofker MH, Koonen DP, Vinciguerra M. 2015. Genetic ablation of macrohistone H2A1 leads to increased leanness, glucose tolerance and energy expenditure in mice fed a high-fat diet International Journal of Obesity, 39 :331-338 DOI Author Url Publisher Url

Vinciguerra M. 2015. Protein intake, chronic liver diseases, and hepatocellular carcinoma Hepatology, 61 :730 DOI Author Url Publisher Url

D'Aronzo M, Vinciguerra M, Mazza T, Panebianco C, Saracino C, Pereira SP, Graziano P, Pazienza V. 2015. Fasting cycles potentiate the efficacy of gemcitabine treatment in in vitro and in vivo pancreatic cancer models Oncotarget, 6 :18545-18557 DOI Author Url Publisher Url

Mazzoccoli G, Mazza T, Vinciguerra M, Castellana S, Scarpa M. 2015. The biological clock and the molecular basis of lysosomal storage diseases 18 :93-105 DOI Author Url Publisher Url

Rahimi M, Vinciguerra M, Daghighi M, özcan B, Akbarkhanzadeh V, Sheedfar F, Amini M, Mazza T, Pazienza V, Motazacker MM, Mahmoudi M, De Rooij FWM, Sijbrands E, Peppelenbosch MP, Rezaee F. 2015. Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans Oncotarget, 6 :29818-29832 DOI Author Url Publisher Url

Sanjabi B, Dashty M, Özcan B, Akbarkhanzadeh V, Rahimi M, Vinciguerra M, Van Rooij F, Al-Lahham S, Sheedfar F, Van Kooten TG, Spek CA, Rowshani AT, Van Der Want J, Klaassen R, Sijbrands E, Peppelenbosch MP, Rezaee F. 2015. Lipid droplets hypertrophy: A crucial determining factor in insulin regulation by adipocytes Scientific Reports, 5 DOI Author Url Publisher Url

McKee C, Sigala B, Soeda J, Mouralidarane A, Morgan M, Mazzoccoli G, Rappa F, Cappello F, Cabibi D, Pazienza V, Selden C, Roskams T, Vinciguerra M, Oben JA. 2015. Amphiregulin activates human hepatic stellate cells and is upregulated in non alcoholic steatohepatitis Scientific Reports, 5 DOI Author Url Publisher Url

Mazzoccoli G, Dagostino MP, Vinciguerra M, Ciccone F, Paroni G, Seripa D, Addante F, Montella RC, De Cosmo S, Sera F, Greco A. 2014. An association study between epicardial fat thickness and cognitive impairment in the elderly American Journal of Physiology - Heart and Circulatory Physiology, 307 :H1269-H1276 DOI Author Url Publisher Url

Barchitta M, Quattrocchi A, Maugeri A, Vinciguerra M, Agodi A. 2014. LINE-1 hypomethylation in blood and tissue samples as an epigenetic marker for cancer risk: A systematic review and meta-analysis PLoS ONE, 9 DOI Author Url Publisher Url

Vinciguerra M. 2014. Normalization of a NAFLD gene expression signature Hepatology, 60 :1445-1445 DOI Author Url Publisher Url

Borghesan M, Mazzoccoli G, Sheedfar F, Oben J, Pazienza V, Vinciguerra M. 2014. Histone variants and lipid metabolism Biochemical Society Transactions, 42 :1409-1413 DOI Author Url Publisher Url

Pazienza V, Pomara C, Cappello F, Calogero R, Carrara M, Mazzoccoli G, Vinciguerra M. 2014. The TRPA1 channel is a cardiac target of mIGF-1/SIRT1 signaling American Journal of Physiology - Heart and Circulatory Physiology, 307 :H939-H944 DOI Author Url Publisher Url

Tavano F, Fontana A, Pellegrini F, Burbaci FP, Rappa F, Cappello F, Copetti M, Maiello E, Lombardi L, Graziano P, Vinciguerra M, di Mola FF, di Sebastiano P, Andriulli A, Pazienza V. 2014. Modeling interactions between Human Equilibrative Nucleoside Transporter-1 and other factors involved in the response to gemcitabine treatment to predict clinical outcomes in pancreatic ductal adenocarcinoma patients Journal of Translational Medicine, 12 DOI Author Url Publisher Url

Planavila A, Villarroya F, Vinciguerra M. 2014. Nutrilent sgnaling and cardiovascular aging Heart and Metabolism, :4-7

de Matthaeis A, Greco A, Dagostino MP, Paroni G, Fontana A, Vinciguerra M, Mazzoccoli G, Seripa D, Vendemiale G. 2014. Effects of hypercapnia on peripheral vascular reactivity in elderly patients with acute exacerbation of chronic obstructive pulmonary disease Clinical Interventions in Aging, 9 :871-878 DOI Author Url Publisher Url

Vinciguerra M, Tevy MFL, Mazzoccoli G. 2014. A ticking clock links metabolic pathways and organ systems function in health and disease Clinical and experimental medicine, 14 :133-140 DOI Author Url Publisher Url

Mazzoccoli G, Vinciguerra M, Papa G, Piepoli A. 2014. Circadian clock circuitry in colorectal cancer World Journal of Gastroenterology, 20 :4197-4207 DOI Author Url Publisher Url

Carter R, Mouralidarane A, Soeda J, Ray S, Pombo J, Saraswati R, Novelli M, Fusai G, Rappa F, Saracino C, Pazienza V, Poston L, Taylor PD, Vinciguerra M, Oben JA. 2014. Non-alcoholic fatty pancreas disease pathogenesis: A role for developmental programming and altered circadian rhythms PLoS ONE, 9 DOI Author Url Publisher Url

Mazzoccoli G, Tevy MF, Borghesan M, Vergini MRD, Vinciguerra M. 2014. Caloric restriction and aging stem cells: The stick and the carrot? Experimental Gerontology, 50 :137-148 DOI Author Url Publisher Url

Mazzoccoli G, Longhitano C, Vinciguerra M. 2014. Cardio-hepatic metabolic derangements and valproic acid Current Clinical Pharmacology, 9 :165-170 DOI Author Url Publisher Url

Rizzo M, Montalto G, Vinciguerra M. 2014. Exploring lipid-related treatment options for the treatment of NASH Current Vascular Pharmacology, 12 :741-744 DOI Author Url Publisher Url

Mazzoccoli G, De Cata A, Piepoli A, Vinciguerra M. 2014. The circadian clock and the hypoxic response pathway in kidney cancer Tumor Biology, 35 :1-7 DOI Author Url Publisher Url

Mazzoccoli G, Vinciguerra M, Oben J, Tarquini R, De Cosmo S. 2014. Non-alcoholic fatty liver disease: The role of nuclear receptors and circadian rhythmicity Liver International, 34 :1133-1152 DOI Author Url Publisher Url

Sheedfar F, Sung MMY, Aparicio-Vergara M, Kloosterhuis NJ, Miquilena-Colina ME, Vargas-Castrillón J, Febbraio M, Jacobs RL, de Bruin A, Vinciguerra M, García-Monzón C, Hofker MH, Dyck JRB, Koonen DPY. 2014. Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease Aging, 6 :281-295 DOI Author Url Publisher Url

Pazienza V, Borghesan M, Mazza T, Sheedfar F, Panebianco C, Williams R, Mazzoccoli G, Andriulli A, Nakanishi T, Vinciguerra M. 2014. SIRT1-metabolite binding histone macroH2A1.1 protects hepatocytes against lipid accumulation Aging, 6 :35-47 DOI Author Url Publisher Url

Panza A, Votino C, Gentile A, Valvano MR, Colangelo T, Pancione M, Micale L, Merla G, Andriulli A, Sabatino L, Vinciguerra M, Prattichizzo C, Mazzoccoli G, Colantuoni V, Piepoli A. 2014. Peroxisome proliferator-activated receptor γ-mediated induction of microRNA-145 opposes tumor phenotype in colorectal cancer Biochimica et Biophysica Acta - Molecular Cell Research, 1843 :1225-1236 DOI Author Url Publisher Url

Vinciguerra M, Mazzoccoli G, Piccoli C, Tataranni T, Andriulli A, Pazienza V. 2013. Exploitation of host clock gene machinery by hepatitis viruses B and C World Journal of Gastroenterology, 19 :8902-8909 DOI Author Url Publisher Url

Sheedfar F, Biase SD, Koonen D, Vinciguerra M. 2013. Liver diseases and aging: Friends or foes? Aging Cell, 12 :950-954 DOI Author Url Publisher Url

Mazzoccoli G, Tomanin R, Mazza T, D'Avanzo F, Salvalaio M, Rigon L, Zanetti A, Pazienza V, Francavilla M, Giuliani F, Vinciguerra M, Scarpa M. 2013. Circadian transcriptome analysis in human fibroblasts from Hunter syndrome and impact of iduronate-2-sulfatase treatment BMC Medical Genomics, 6 DOI Author Url Publisher Url

Bonny O, Vinciguerra M, Gumz ML, Mazzoccoli G. 2013. Molecular bases of circadian rhythmicity in renal physiology and pathology Nephrology Dialysis Transplantation, 28 :2421-2431 DOI Author Url Publisher Url

Sigala B, McKee C, Soeda J, Pazienza V, Morgan M, Lin CI, Selden C, Vander Borght S, Mazzoccoli G, Roskams T, Vinciguerra M, Oben JA. 2013. Sympathetic Nervous System Catecholamines and Neuropeptide Y Neurotransmitters Are Upregulated in Human NAFLD and Modulate the Fibrogenic Function of Hepatic Stellate Cells PLoS ONE, 8 DOI Author Url Publisher Url

Pazienza V, Niro GA, Fontana R, Vinciguerra M, Andriulli A. 2013. Advance in molecular diagnostic tools for hepatitis B virus detection Clinical Chemistry and Laboratory Medicine, 51 :1707-1717 DOI Author Url Publisher Url

Vinciguerra M. 2013. Old age and steatohepatitis: A dangerous liaison? Hepatology, 58 :830-831 DOI Author Url Publisher Url

Panza A, Pazienza V, Ripoli M, Benegiamo G, Gentile A, Valvano MR, Augello B, Merla G, Prattichizzo C, Tavano F, Ranieri E, Sebastiano PD, Vinciguerra M, Andriulli A, Mazzoccoli G, Piepoli A. 2013. Interplay between SOX9, β-catenin and PPARγ activation in colorectal cancer Biochimica et Biophysica Acta - Molecular Cell Research, 1833 :1853-1865 DOI Author Url Publisher Url

Planavila A, Redondo I, Hondares E, Vinciguerra M, Munts C, Iglesias R, Gabrielli LA, Sitges M, Giralt M, Van Bilsen M, Villarroya F. 2013. Fibroblast growth factor 21 protects against cardiac hypertrophy in mice Nature Communications, 4 DOI Author Url Publisher Url

Anderson G, Beischlag TV, Vinciguerra M, Mazzoccoli G. 2013. The circadian clock circuitry and the AHR signaling pathway in physiology and pathology Biochemical Pharmacology, 85 :1405-1416 DOI Author Url Publisher Url

Benegiamo G, Vinciguerra M, Guarnieri V, Niro G, Andriulli A, Pazienza V. 2013. Hepatitis delta virus induces specific DNA methylation processes in Huh-7 liver cancer cells FEBS Letters, 587 :1424-1428 DOI Author Url Publisher Url

Tevy MF, Giebultowicz J, Pincus Z, Mazzoccoli G, Vinciguerra M. 2013. Aging signaling pathways and circadian clock-dependent metabolic derangements Trends in Endocrinology and Metabolism, 24 :229-237 DOI Author Url Publisher Url

Podrini C, Borghesan M, Greco A, Pazienza V, Mazzoccoli G, Vinciguerra M. 2013. Redox homeostasis and epigenetics in non-alcoholic fatty liver disease (NAFLD) Current Pharmaceutical Design, 19 :2737-2746 DOI Author Url Publisher Url

Benegiamo G, Mazzoccoli G, Cappello F, Rappa F, Scibetta N, Oben J, Greco A, Williams R, Andriulli A, Vinciguerra M, Pazienza V. 2013. Mutual Antagonism between Circadian Protein Period 2 and Hepatitis C Virus Replication in Hepatocytes PLoS ONE, 8 DOI Author Url Publisher Url

Rappa F, Greco A, Podrini C, Cappello F, Foti M, Bourgoin L, Peyrou M, Marino A, Scibetta N, Williams R, Mazzoccoli G, Federici M, Pazienza V, Vinciguerra M. 2013. Correction: Immunopositivity for histone MacroH2A1 isoforms marks steatosis-associated hepatocellular carcinoma (PLoS ONE) PLoS ONE, 8 DOI Publisher Url

Vinciguerra M. 2013. Targeting chromatin remodelers to treat hepatocellular carcinoma Hepatology, 57 :1287 DOI Author Url Publisher Url

Sciacca S, Pilato M, Mazzoccoli G, Pazienza V, Vinciguerra M. 2013. Anti-correlation between longevity gene SirT1 and Notch signaling in ascending aorta biopsies from patients with bicuspid aortic valve disease Heart and Vessels, 28 :268-275 DOI Author Url Publisher Url

Rappa F, Greco A, Podrini C, Cappello F, Foti M, Bourgoin L, Peyrou M, Marino A, Scibetta N, Williams R, Mazzoccoli G, Federici M, Pazienza V, Vinciguerra M. 2013. Immunopositivity for Histone MacroH2A1 Isoforms Marks Steatosis-Associated Hepatocellular Carcinoma PLoS ONE, 8 DOI Author Url Publisher Url

Mazza T, Castellana S, Andriulli A, Auffray C, Vinciguerra M, Pazienza V. 2013. Affinity analysis of differentially expressed genes in hepatocytes expressing HCV core genotype 1b or 3a BioSystems, 114 :64-68 DOI Author Url Publisher Url

Vinciguerra M, Borghesan M, Pazienza V, Piepoli A, Palmieri O, Tarquini R, Tevy MF, De Cata A, Mazzoccoli G. 2013. The transcriptional regulators, the immune system and the the circadian clock. Journal of biological regulators and homeostatic agents, 27 :9-22 Author Url

Vinciguerra M. 2013. Paracrine mechanisms, signaling and epigenetics in repairing damaged tissue Recent Patents on Regenerative Medicine, 3 :1-4 DOI Publisher Url

Mazzoccoli G, Francavilla M, Pazienza V, Benegiamo G, Piepoli A, Vinciguerra M, Giuliani F, Yamamoto T, Takumi T. 2012. Differential patterns in the periodicity and dynamics of clock gene expression in mouse liver and stomach Chronobiology International, 29 :1300-1311 DOI Author Url Publisher Url

Pazienza V, Vinciguerra M, Mazzoccoli G. 2012. PPARs signaling and cancer in the gastrointestinal system PPAR Research, DOI Author Url Publisher Url

Planavila A, Dominguez E, Navarro M, Vinciguerra M, Iglesias R, Giralt M, Lope-Piedrafita S, Ruberte J, Villarroya F. 2012. Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart Journal of Molecular and Cellular Cardiology, 53 :521-531 DOI Author Url Publisher Url

Pazienza V, Tavano F, Benegiamo G, Vinciguerra M, Burbaci FP, Copetti M, Di Mola FF, Andriulli A, Di Sebastiano P. 2012. Correlations among PPARγ, DNMT1, and DNMT3B expression levels and pancreatic cancer PPAR Research, DOI Author Url Publisher Url

Benegiamo G, Vinciguerra M, Mazzoccoli G, Piepoli A, Andriulli A, Pazienza V. 2012. DNA methyltransferases 1 and 3b expression in Huh-7 cells expressing HCV core protein of different genotypes Digestive Diseases and Sciences, 57 :1598-1603 DOI Author Url Publisher Url

Fontana L, Vinciguerra M, Longo VD. 2012. Growth factors, nutrient signaling, and cardiovascular aging Circulation Research, 110 :1139-1150 DOI Author Url Publisher Url

Mazzoccoli G, Francavilla M, Giuliani F, Aucella F, Vinciguerra M, Pazienza V, Piepoli A, Benegiamo G, Liu S, Cai Y. 2012. Clock gene expression in mouse kidney and testis: Analysis of periodical and dynamical patterns Journal of Biological Regulators and Homeostatic Agents, 26 :303-311 Author Url

Mazzoccoli G, Cai Y, Liu S, Francavilla M, Giuliani F, Piepoli A, Pazienza V, Vinciguerra M, Yamamoto T, Takumi T. 2012. REV-ERBα and the clock gene machinery in mouse peripheral tissues: A possible role as a synchronizing hinge Journal of Biological Regulators and Homeostatic Agents, 26 :265-276 Author Url

Deblon N, Bourgoin L, Veyrat-Durebex C, Peyrou M, Vinciguerra M, Caillon A, Maeder C, Fournier M, Montet X, Rohner-Jeanrenaud F, Foti M. 2012. Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats British Journal of Pharmacology, 165 :2325-2340 DOI Author Url Publisher Url

Mazzoccoli G, Pazienza V, Panza A, Valvano MR, Benegiamo G, Vinciguerra M, Andriulli A, Piepoli A. 2012. ARNTL2 and SERPINE1: Potential biomarkers for tumor aggressiveness in colorectal cancer Journal of Cancer Research and Clinical Oncology, 138 :501-511 DOI Author Url Publisher Url

Vinciguerra M, Santini MP, Martinez C, Pazienza V, Claycomb WC, Giuliani A, Rosenthal N. 2012. mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart Aging Cell, 11 :139-149 DOI Author Url Publisher Url

Pazienza V, Piepoli A, Panza A, Valvano MR, Benegiamo G, Vinciguerra M, Andriulli A, Mazzoccoli G. 2012. SIRT1 and the clock gene machinery in colorectal cancer Cancer Investigation, 30 :98-105 DOI Author Url Publisher Url

Mazzoccoli G, Sothern RB, Francavilla M, Giuliani F, Carughi S, Muscarella LA, Fazio VM, Parrella P, Vinciguerra M, Tarquini R. 2012. Hormone and cytokine circadian alteration in non-small cell lung cancer patients International Journal of Immunopathology and Pharmacology, 25 :691-702 DOI Author Url Publisher Url

Mazzoccoli G, Pazienza V, Vinciguerra M. 2012. Clock genes and clock-controlled genes in the regulation of metabolic rhythms Chronobiology International, 29 :227-251 DOI Author Url Publisher Url

Tonkin J, Villarroya F, Puri PL, Vinciguerra M. 2012. SIRT1 signaling as potential modulator of skeletal muscle diseases Current Opinion in Pharmacology, 12 :372-376 DOI Author Url Publisher Url

Bolasco G, Calogero R, Carrara M, Al Banchaabouchi M, Bilbao D, Mazzoccoli G, Vinciguerra M. 2012. Cardioprotective mIGF-1/SIRT1 signaling induces hypertension, leukocytosis and fear response in mice Aging, 4 :402-416 DOI Author Url Publisher Url

Boon RA, Seeger T, Heydt S, Fischer A, Hergenreider E, Horrevoets AJG, Vinciguerra M, Rosenthal N, Sciacca S, Pilato M, Van Heijningen P, Essers J, Brandes RP, Zeiher AM, Dimmeler S. 2011. MicroRNA-29 in aortic dilation: Implications for aneurysm formation Circulation Research, 109 :1115-1119 DOI Author Url Publisher Url

Ripoli M, Barbano R, Balsamo T, Piccoli C, Brunetti V, Coco M, Mazzoccoli G, Vinciguerra M, Pazienza V. 2011. Hypermethylated levels of E-cadherin promoter in Huh-7 cells expressing the HCV core protein Virus Research, 160 :74-81 DOI Author Url Publisher Url

Clément S, Peyrou M, Sanchez-Pareja A, Bourgoin L, Ramadori P, Suter D, Vinciguerra M, Guilloux K, Pascarella S, Rubbia-Brandt L, Negro F, Foti M. 2011. Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets Hepatology, 54 :38-49 DOI Author Url Publisher Url

Mazzoccoli G, Sothern RB, Greco A, Pazienza V, Vinciguerra M, Liu S, Cai Y. 2011. Time-related dynamics of variation in core clock gene expression levels in tissues relevant to the immune system International Journal of Immunopathology and Pharmacology, 24 :869-879 DOI Author Url Publisher Url

Vinciguerra M, Musaro A, Rosenthal N. 2010. Regulation of muscle atrophy in aging and disease Advances in Experimental Medicine and Biology, 694 :211-233 DOI Author Url Publisher Url

Zanchi A, Maillard M, Jornayvaz FR, Vinciguerra M, Deleaval P, Nussberger J, Burnier M, Pechere-Bertschi A. 2010. Effects of the peroxisome proliferator-activated receptor (PPAR)-γ agonist pioglitazone on renal and hormonal responses to salt in diabetic and hypertensive individuals Diabetologia, 53 :1568-1575 DOI Author Url Publisher Url

Pazienza V, Vinciguerra M, Andriulli A, Mangia A. 2010. Hepatitis C virus core protein genotype 3a increases SOCS-7 expression through PPAR-γ in Huh-7 cells Journal of General Virology, 91 :1678-1686 DOI Author Url Publisher Url

Vinciguerra M, Hede M, Rosenthal N. 2010. Comments on Point:Counterpoint: IGF is/is not the major physiological regulator of muscle mass. IGF-1 is a major regulator of muscle mass during growth but not for adult myofiber hypertrophy. Journal of applied physiology (Bethesda, Md. : 1985), 108 :1829-1830 DOI Author Url Publisher Url

Vinciguerra M, Fulco M, Ladurner A, Sartorelli V, Rosenthal N. 2010. SirT1 in muscle physiology and disease: Lessons from mouse models DMM Disease Models and Mechanisms, 3 :298-303 DOI Author Url Publisher Url

Vinciguerra M, Santini MP, Claycomb WC, Ladurner AG, Rosenthal N. 2010. Local IGF-1 isoform protects cardiomyocytes from hypertrophic and oxidative stresses via SirT1 activity Aging, 2 :43-62 DOI Author Url Publisher Url

Vinciguerra M, Sgroi A, Veyrat-Durebex C, Rubbia-Brandt L, Buhler LH, Foti M. 2009. Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog(PTEN) via microRNA-21 up-regulation in hepatocytes Hepatology, 49 :1176-1184 DOI Author Url Publisher Url

Vinciguerra M, Carrozzino F, Peyrou M, Carlone S, Montesano R, Benelli R, Foti M. 2009. Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN Journal of Hepatology, 50 :1132-1141 DOI Author Url Publisher Url

Veyrat-Durebex C, Montet X, Vinciguerra M, Gjinovci A, Meda P, Foti M, Rohner-Jeanrenaud F. 2009. The Lou/C rat: A model of spontaneous food restriction associated with improved insulin sensitivity and decreased lipid storage in adipose tissue American Journal of Physiology - Endocrinology and Metabolism, 296 DOI Author Url Publisher Url

Vinciguerra M. 2009. Aldosterone, but not increased Na+ influx or NF-kappaB activation, increases kidney-specific WNK1 gene expression in renal collecting duct cells. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, 41 :67-70 DOI Author Url Publisher Url

Leroy V, De Seigneux S, Agassiz V, Hasler U, Rafestin-Oblin ME, Vinciguerra M, Martin PY, Féraille E. 2009. Aldosterone activates NF-κB in the collecting duct Journal of the American Society of Nephrology, 20 :131-144 DOI Author Url Publisher Url

Cederroth CR, Vinciguerra M, Gjinovci A, Kühne F, Klein M, Cederroth M, Caille D, Suter M, Neumann D, James RW, Doerge DR, Wallimann T, Meda P, Foti M, Rohner-Jeanrenaud F, Vassalli JD, Nef S. 2008. Dietary phytoestrogens activate AMP-Activated protein kinase with improvement in lipid and glucose metabolism Diabetes, 57 :1176-1185 DOI Author Url Publisher Url

Vinciguerra M, Foti M. 2008. PTEN at the crossroad of metabolic diseases and cancer in the liver Annals of Hepatology, 7 :192-199 DOI Author Url Publisher Url

Vinciguerra M, Veyrat-Durebex C, Moukil MA, Rubbia-Brandt L, Rohner-Jeanrenaud F, Foti M. 2008. PTEN Down-Regulation by Unsaturated Fatty Acids Triggers Hepatic Steatosis via an NF-κBp65/mTOR-Dependent Mechanism Gastroenterology, 134 :268-280 DOI Author Url Publisher Url

Cederroth CR, Vinciguerra M, Kühne F, Madani R, Doerge DR, Visser TJ, Foti M, Rohner-Jeanrenaud F, Vassalli JD, Nef S. 2007. A phytoestrogen-rich diet increases energy expenditure and decreases adiposity in mice Environmental Health Perspectives, 115 :1467-1473 DOI Author Url Publisher Url

De Gottardi A, Vinciguerra M, Sgroi A, Moukil M, Ravier-Dall'Antonia F, Pazienza V, Pugnale P, Foti M, Hadengue A. 2007. Microarray analyses and molecular profiling of steatosis induction in immortalized human hepatocytes Laboratory Investigation, 87 :792-806 DOI Author Url Publisher Url

Vinciguerra M, Foti M. 2006. PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling Archives of Physiology and Biochemistry, 112 :89-104 DOI Author Url Publisher Url

Hasler U, Vinciguerra M, Vandewalle A, Martin PY, Féraille E. 2005. Dual effects of hypertonicity on aquaporin-2 expression in cultured renal collecting duct principal cells Journal of the American Society of Nephrology, 16 :1571-1582 DOI Author Url Publisher Url

Vinciguerra M, Hasler U, Mordasini D, Roussel M, Capovilla M, Ogier-Denis E, Vandewalle A, Martin PY, Feraille E. 2005. Cytokines and sodium induce protein kinase A-dependent cell-surface Na,K-ATPase recruitment via dissociation of NF-κB/IκB/protein kinase A catalytic subunit complex in collecting duct principal cells Journal of the American Society of Nephrology, 16 :2576-2585 DOI Author Url Publisher Url

Vinciguerra M, Mordasini D, Vandewalle A, Feraille E. 2005. Hormonal and nonhormonal mechanisms of regulation of the Na,K-pump in collecting duct principal cells Seminars in Nephrology, 25 :312-321 DOI Author Url Publisher Url

Vinciguerra M, Arnaudeau S, Mordasini D, Rousselot M, Bens M, Vandewalle A, Martin PY, Hasler U, Feraille E. 2004. Extracellular hypotonicity increases Na,K-ATPase cell surface expression via enhanced Na+ influx in cultured renal collecting duct cells Journal of the American Society of Nephrology, 15 :2537-2547 DOI Author Url Publisher Url

Vinciguerra M, Deschênes G, Hasler U, Mordasini D, Rousselot M, Doucet A, Vandewalle A, Martin PY, Féraille E. 2003. Intracellular Na+ controls cell surface expression of Na,K-ATPase via a cAMP-independent PKA pathway in mammalian kidney collecting duct cells Molecular Biology of the Cell, 14 :2677-2688 DOI Author Url Publisher Url

Féraille E, Mordasini D, Gonin S, Deschênes G, Vinciguerra M, Doucet A, Vandewalle A, Summa V, Verrey F, Martin PY. 2003. Mechanism of control of Na,K-ATPase in principal cells of the mammalian collecting duct Annals of the New York Academy of Sciences, 986 :570-578 DOI Author Url Publisher Url

Chapters

Giallongo S, Lo Re O, Resnick I, Raffaele M, Vinciguerra M. 2023. Gene Editing and Human iPSCs in Cardiovascular and Metabolic Diseases Advances in Experimental Medicine and Biology 1396 :275-298 DOI Author Url Publisher Url

Giallongo S, Lo Re O, Vinciguerra M. 2022. DNA damage and histone variants Epigenetics and DNA Damage :33-53 9780323910828 DOI Publisher Url

Cordero P, Vinciguerra M, Oben JA. 2019. Maternal perinatal nutrition and offspring programming Principles of Nutrigenetics and Nutrigenomics: Fundamentals of Individualized Nutrition :121-127 9780128045879 DOI Publisher Url

Vinciguerra M, Lionetti V, Ventura C, Rosenthal N. 2012. Cardiac versus non-cardiac stem cells to repair the heart: The role of autocrine/paracrine signals Advances in Stem Cell Research :367-382 9781617799396 DOI Publisher Url

Other

Romito I, Porru M, Braghini MR, Pompili L, Panera N, Crudele A, Gnani D, De Stefanis C, Scarsella M, Pomella S, Mortera SL, de Billy E, Conti AL, Marzano V, Putignani L, Vinciguerra M, Balsano C, Pastore A, Rota R, Tartaglia M, Leonetti C, Alisi A. 2022. Correction to: Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects (Journal of Experimental & Clinical Cancer Research, (2021), 40, 1, (364), 10.1186/s13046-021-02154-8) Journal of Experimental and Clinical Cancer Research, 41 DOI Author Url Publisher Url

Calimport SRG, Bentley BL, Stewart C, Pawelec G, Scuteri A, Vinciguerra M, Slack C, Chen D, Harries LW, Marchant G, Fleming GA, Conboy M, Antebi A, Small GW, Gil J, Lakatta EG, Richardson A, Rosen C, Nikolich K, Wyss-Coray T, Steinman L, Montine T, de Magalhaes JP, Campisi J, Church G. 2019. To help aging populations, classify organismal senescence SCIENCE, 366 :576-+ DOI Author Url Publisher Url

Howitt-Dring H. Editor Howitt-Dring L. Writing in Practice: The Journal of Creative Writing Research,

Editorial/letter to the editor

Raffaele M, Vinciguerra M. 2022. Targeting anxiety and senescence with senolytics Aging, 14 :2438-2439 DOI Author Url Publisher Url

Books (authored)

Vinciguerra M, Sanchez P. 2020. Molecular Nutrition: Mother and Infant :1-431 9780128138625 DOI Publisher Url

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