Liverpool Skylilne

Pharmacy and Biomolecular Sciences

Dr Touraj Ehtezazi

Dr Touraj Ehtezazi

Publications

Journal Articles

Ehtezazi T, Algellay M, Islam Y, Roberts M, Dempster NM, Sarker SD. 2017. The Application of 3D Printing in the Formulation of Multilayered Fast Dissolving Oral Films. J Pharm Sci, >DOI >Link

Ehtezazi T, Davies MJ, Seton L, Morgan MN, Ross S, Martin GD, Hutchings IM. 2015. Optimizing the primary particle size distributions of pressurized metered dose inhalers by using inkjet spray drying for targeting desired regions of the lungs. Drug Dev Ind Pharm, 41 :279-291 >DOI >Link

Ehtezazi T, Dempster NM, Martin GD, Hoath SD, Hutchings IM. 2014. Development of high-throughput glass inkjet devices for pharmaceutical applications Journal of Pharmaceutical Sciences, 103 :3733-3742 >DOI

Jones RW, Chaudary S, Ehtezazi T, Sheikh M. 2014. Review of core principles and best practice in the teaching of aseptic manufacturing in UK schools of pharmacy European Journal of Parenteral and Pharmaceutical Sciences, 19 :170-178

Ehtezazi T, Dempster NM, Martin GD, Hoath SD, Hutchings IM. 2014. Development of High-Throughput Glass Inkjet Devices for Pharmaceutical Applications JOURNAL OF PHARMACEUTICAL SCIENCES, 103 :3733-3742 >DOI >Link

Ehtezazi T, Turner MA. 2013. The application of mechanical aerosol delivery systems in an in vitro model of mechanically ventilated neonates. Recent Pat Drug Deliv Formul, 7 :174-183 >Link

Ehtezazi T. 2012. Recent patents in pressurised metered dose inhalers. Recent Pat Drug Deliv Formul, 6 :31-44 >Link

Roberts M, Ehtezazi T, Compernolle A, Amin K. 2011. The effect of spray drying on the compaction properties of hypromellose acetate succinate. Drug Dev Ind Pharm, 37 :268-273 >DOI >Link

Ehtezazi T, Saleem I, Shrubb I, Allanson DR, Jenkinson ID, O'Callaghan C. 2010. The interaction between the oropharyngeal geometry and aerosols via pressurised metered dose inhalers. Pharm Res, 27 :175-186 >DOI >Link

Ehtezazi T, Allanson DR, Jenkinson ID, Shrubb I, O'Callaghan C. 2008. Investigating improving powder deagglomeration via dry powder inhalers at a low inspiratory flow rate by employing add-on spacers. J Pharm Sci, 97 :5212-5221 >DOI >Link

Ehtezazi T, Allanson DR, Jenkinson ID, O'Callaghan C. 2006. Effect of oropharyngeal length in drug lung delivery via suspension pressurized metered dose inhalers. Pharm Res, 23 :1364-1372 >DOI >Link

Patel J, Ehtezazi T, Dyas AM, Riby P, Larhrib H. 2005. Dextran as a carrier for dry powder inhalation formulations JOURNAL OF PHARMACY AND PHARMACOLOGY, 57 :S96-S96 >Link

Ehtezazi T, Kodjaian K, Larhrib H. 2005. Use of corrugated gelatin particles in dry powder inhalation aerosols JOURNAL OF PHARMACY AND PHARMACOLOGY, 57 :S86-S87 >Link

Ehtezazi T, Horsfield MA, Barry PW, Goodenough P, O'callaghan C. 2005. Effect of device inhalational resistance on the three-dimensional configuration of the upper airway. J Pharm Sci, 94 :1418-1426 >DOI >Link

Ehtezazi T, Southern KW, Allanson D, Jenkinson I, O'Callaghan C. 2005. Suitability of the upper airway models obtained from MRI studies in simulating drug lung deposition from inhalers. Pharm Res, 22 :166-170 >Link

Ehtezazi T, Horsfield MA, Barry PW, O'Callaghan C. 2004. Dynamic change of the upper airway during inhalation via aerosol delivery devices. J Aerosol Med, 17 :325-334 >DOI >Link

Ehtezazi T, Rungsardthong U, Stolnik S. 2003. Thermodynamic analysis of polycation-DNA interaction applying titration microcalorimetry LANGMUIR, 19 :9387-9394 >DOI >Link

Rungsardthong U, Ehtezazi T, Bailey L, Armes SP, Garnett MC, Stolnik S. 2003. Effect of polymer ionization on the interaction with DNA in nonviral gene delivery systems. Biomacromolecules, 4 :683-690 >DOI >Link

Ehtezazi T, Govender T, Stolnik S. 2000. Hydrogen bonding and electrostatic interaction contributions to the interaction of a cationic drug with polyaspartic acid. Pharm Res, 17 :871-878 >Link

Ehtezazi T, Washington C. 2000. Controlled release of macromolecules from PLA microspheres: using porous structure topology. J Control Release, 68 :361-372 >Link

Govender T, Riley T, Ehtezazi T, Garnett MC, Stolnik S, Illum L, Davis SS. 2000. Defining the drug incorporation properties of PLA-PEG nanoparticles. Int J Pharm, 199 :95-110 >Link

Ehtezazi T, Washington C, Melia CD. 2000. First order release rate from porous PLA microspheres with limited exit holes on the exterior surface. J Control Release, 66 :27-38 >Link

Ehtezazi T, Washington C, Melia CD. 1999. Determination of the internal morphology of poly (D,L-lactide) microspheres using stereological methods. J Control Release, 57 :301-314 >Link

Govender T, Ehtezazi T, Stolnik S, Illum L, Davis SS. 1999. Complex formation between the anionic polymer (PAA) and a cationic drug (procaine HCI): characterization by microcalorimetric studies. Pharm Res, 16 :1125-1131 >Link

Ehtezazi T, Melia CD, Washington C. 1997. Obtaining pore size distributions within porous microspheres using stereological methods Proceedings of the Controlled Release Society, :629-630

Ghassabian S, Ehtezazi T, Forutan SM, Mortazavi SA. 1996. Dexamethasone-loaded magnetic albumin microspheres: Preparation and in vitro release INTERNATIONAL JOURNAL OF PHARMACEUTICS, 130 :49-55 >DOI >Link

Posters

Ehtezazi T, Turner M, Alzoubi T. 2010. An in Vitro Model to Simulate More Realistic Aerosol Lung Deposition in Mechanically Ventilated Neonates. Drug Delivery to the Lungs XXI

Ehtezazi T, Turner M. 2009. Reducing the Amount of Alcohol Delivered to Neonates via Pressurised Metered Dose Inhalers Containing Alcohol. Drug Delivery to the Lungs XX, London, Dec 2009

Harrington L, Versteed HK, Ehtezazi T, O’Callaghan C, Barry PW, Horsfield MA. 2001. Comparison of the development of a pharmaceutical aerosol in USP and “biological” throats using computational fluid dynamics.

Ehtezazi T, Horsfield MA, Barry PW, O’Callaghan C. 2001. Smoothing the stepwise structure of the upper airway reconstructed from the rapid MR scans. Drug Delivery to the Lungs. 2001, XII

Ehtezazi T, Horsfield MA, Barry PW, O’Callaghan C. 2000. 3D Reconstruction of the Upper Airway During Inhalation from Drug Delivery Systems. DDL, London, Dec, 2001

Ehtezazi T, Melia CD, Washington C. 1997. Using Stereological Methods to Determine the Pore Size Distribution of Microspheres The 24th International Symposium on Controlled Release of Bioactive Materials : proceedings 1997 : Stockholmsmässan, Stockholm, Sweden, June 15-19, 1997

Chapters

Hugo WB, Denyer SP, Hodges NA, Gorman SP, Ford JL. 2004. Hugo and Russell's pharmaceutical microbiology :323-345 Wiley-Blackwell 9780632064670

Conference Publication (journal proceedings)

Sindu S, Ehtezazi T. 2003. Reformulation of magnesium sulphate paste BPC

Ehtezazi T, Washington C, Melia CD. 1999. Effect of thickening agents in porous PLA microspheres on the release of macromolecules Proceedings of the Controlled Release Society, :685-686

Ehtezazi T, Govender T, Jenssen D, Stolnik S, Davis SS. 1999. The role of hydrogen binding in complex formation between cationic drugs and poly (aspartic acid) Proceedings of the Controlled Release Society, :659-660

Ehtezazi T, Washington C, Melia CD. 1998. Limited surface access of porous PLA microspheres Proceedings of the Controlled Release Society, :707-708

Engagement & Impact

Award:

Award title: Developing novel pressurised metered dose inhalers, Awarding body: Coster (Italy)

Award title: Immobilisation of rhDNase on biodegradable microspheres, Awarding body: GenenTech

Research Grants Awarded:

AstraZeneca foundations, The Effect of the Upper Airway on the Deposition of Inhaled Medication, Prfessor Christopher O'Callaghan, Grant value (£): £20,000, Duration of research project: 12 Month

Novartis Vaccines, Optimising aseptic procedures, Profesdsor James Ford, Grant value (£): £114,750, Duration of research project: 12 month

Janssen Pharmaceutical NV, Beerse, Belgium, The effects of spray drying on the compaction properties of hypromellose acetate succinate, Dr Matt-Roberts, Grant value (£): £17,400

3M Healthcare, Development of inkjet spray drying for inhalers., Grant value (£): 60,000, Duration of research project: 36 month